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    XSXCFW

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    Ikram Hikmatyar
    Fibrinolytics are indicated for acute myocardial infarction with symptoms for 6-12 hours, ST segment elevations on EKG in at least two leads, and no interventional management available. Absolute contraindications include previous hemorrhagic stroke, CVA in past year, intracranial neoplasm, active internal bleeding, suspected aortic dissection, and diabetic retinopathy. Streptokinase dose is 1.5 million units over 60 minutes and alteplase dose for >67kg is 100mg with 15mg initial IV bolus and 50mg infused over 30 minutes.

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    XSXCFW

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    Ikram Hikmatyar
    19 views2 pages
    Fibrinolytics are indicated for acute myocardial infarction with symptoms for 6-12 hours, ST segment elevations on EKG in at least two leads, and no interventional management available. Absolute contraindications include previous hemorrhagic stroke, CVA in past year, intracranial neoplasm, active internal bleeding, suspected aortic dissection, and diabetic retinopathy. Streptokinase dose is 1.5 million units over 60 minutes and alteplase dose for >67kg is 100mg with 15mg initial IV bolus and 50mg infused over 30 minutes.

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    Fibrinolytics are indicated for acute myocardial infarction with symptoms for 6-12 hours, ST segment elevations on EKG in at least two leads, and no interventional management available. Absolute contraindications include previous hemorrhagic stroke, CVA in past year, intracranial neoplasm, active internal bleeding, suspected aortic dissection, and diabetic retinopathy. Streptokinase dose is 1.5 million units over 60 minutes and alteplase dose for >67kg is 100mg with 15mg initial IV bolus and 50mg infused over 30 minutes.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    19 views2 pages

    XSXCFW

    Uploaded by

    Ikram Hikmatyar
    Fibrinolytics are indicated for acute myocardial infarction with symptoms for 6-12 hours, ST segment elevations on EKG in at least two leads, and no interventional management available. Absolute contraindications include previous hemorrhagic stroke, CVA in past year, intracranial neoplasm, active internal bleeding, suspected aortic dissection, and diabetic retinopathy. Streptokinase dose is 1.5 million units over 60 minutes and alteplase dose for >67kg is 100mg with 15mg initial IV bolus and 50mg infused over 30 minutes.

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    Fibrinolytics

    Indications:
    1. Symptoms compatible with acute myocardial infarction
    2. Time to treatment of 6 hours to 12 hours
    3. EKG with at least 1 mm ST segment elevations in at least two contiguous leads
    4. Interventional management is not available

    Contraindications to therapy:

    Absolute
    1. Previous hemorrhagic stroke at anytime
    2. Cardiovascular accident (CVA or stroke) in the past year
    3. Known intracranial neoplasm
    4. Active internal bleeding (exclude menses)
    5. Suspected aortic dissection
    6. Diabetic retinopathy

    Relative
    1. Significantly elevated blood pressure (>180/100 mm Hg)
    2. History of prior CVA
    3. Current use of anticoagulants (with an INR >2-3)
    4. Trauma within the past 2 weeks
    5. Known bleeding diathesis
    6. Prolonged cardiopulmonary resuscitation (>10 min)
    7. Major surgery in past 3 weeks
    8. Noncompressible vascular punctures
    9. Recent internal bleeding (2 to 4 weeks)
    10. Prior allergic reaction to fibrinolytic
    11. Pregnancy
    12. Active peptic ulcer disease
    13. History of chronic severe hypertension

    Dose

    Streptokinase - 1.5 million units over 60 min

    Alteplase - >67 kg: 100 mg; 15 mg initial IV bolus, 50 mg infused ove

    Fibrinolytics

    Indications:
    1. Symptoms compatible with acute myocardial infarction
    2. Time to treatment of 6 hours to 12 hours
    3. EKG with at least 1 mm ST segment elevations in at least two contiguous leads
    4. Interventional management is not available

    Contraindications to therapy:
    Absolute
    1. Previous hemorrhagic stroke at anytime
    2. Cardiovascular accident (CVA or stroke) in the past year
    3. Known intracranial neoplasm
    4. Active internal bleeding (exclude menses)
    5. Suspected aortic dissection
    6. Diabetic retinopathy

    Relative
    1. Significantly elevated blood pressure (>180/100 mm Hg)
    2. History of prior CVA
    3. Current use of anticoagulants (with an INR >2-3)
    4. Trauma within the past 2 weeks
    5. Known bleeding diathesis
    6. Prolonged cardiopulmonary resuscitation (>10 min)
    7. Major surgery in past 3 weeks
    8. Noncompressible vascular punctures
    9. Recent internal bleeding (2 to 4 weeks)
    10. Prior allergic reaction to fibrinolytic
    11. Pregnancy
    12. Active peptic ulcer disease
    13. History of chronic severe hypertension

    Dose

    Streptokinase - 1.5 million units over 60 min

    Alteplase - >67 kg: 100 mg; 15 mg initial IV bolus, 50 mg infused ove

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