Diabetes Cheat Sheet

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Tips for Inpatient Diabetes Management

Types of insulins
Onset Peak Duration
Lispro, Aspart or
5-15 min 1-2 hours 3-4 hours
Glulisine (Apidra)
Regular 30-60 min 2-4 hours 4-6 hours
NPH/Lente 1-2 hours 4-8 hours 14-18 hours
Ultralente 2-4 hours Unpredictable 16-20 hours
Glargine 1-2 hours Flat 24 hours

Insulin patterns for patients eating meals


Strategy 1:
1. Determine 24 hr basal requirement: by multiplying 8 hr overnight requirement x 3 or 50%of the total insulin used/24 hrs
2. Reduce by 20% for safety (reduce by 40% if medically improving rapidly)
3. Give as Glargine once daily or NPH twice daily (see below)
4. Adjust basal based on AM glucose
5. Calculate meal doses using same basal requirement, give short-acting divided among meals (usually B 30%, L 30%, D 40%)
• If using NPH/regular, can increase AM NPH and give regular just at B, D (shown below, see insulin transition orders)
• Can give Lispro or Aspart after meal if PO intake uncertain

If 24 hr requirement unknown, start with 0.6-0.8 units/kg/day

3 injections a day – NPH in AM, HS, short-acting at breakfast and


dinner (minimum for Type 1 patients)

B L D HS

Basal-Bolus Insulin: Glargine + Short-acting Glargine

B L D HS

Prednisone Strategy 1: Increase premeal regular, particularly lunch and


dinner
1. Determine 24 hr requirement (e.g., from insulin drip)
2. Reduce by 20% for safety
3. Give either Glargine 40% acB OR NPH 25% acB, 15% at HS
(or determine HS NPH dose by overnight 8 hour insulin drip amt)
4. Give rapid acting 15% acB, 20% acL, 25% acD
B L D HS
Prednisone Strategy 2: AM, noon and hs NPH, premeal short-acting
1. Determine 8 hr overnight requirement (10 PM-6 AM) and daytime 16 hour requirement (6 AM-10 PM)
2. Reduce by 20% for safety
3. Give half of the daytime requirement as NPH, 25% acB and 25% acL
4. Give the 8 hr overnight requirement as NPH at HS
5. Give rest as rapid acting in equal doses acB, acL, acD

B L D HS B L D HS

If NPO for procedure:’ Give glargine (or ½ NPH), hold short-acting until eating
Lispro or Aspart

Glargine

8 12 6 10

Supplemental Insulin – See Supplementary Insulin Orders for standard scale


To calculate individualized scale:
Calculate sensitivity ratio:
Determine total daily dose (TDD)
Sensitivity ratio = 1700/TDD = amount 1 unit of insulin will drop BG
Adjust supplemental insulin scale based on response to this amt of insulin

Carb counting
Calculate Carb:Insulin ratio:
Determine total daily dose (TDD)
Carb:Insulin ratio is sensitivity ratio divided by 3 (1700/TDD)/3 = grams of carbohydrate covered by one unit of insulin

Enteral or parenteral nutrition (continuous)


Determine 24 hr requirement, give as glargine once (or twice) a day, NPH every 6-8 hours
Have D5 ready in case nutrition interrupted

Bolus tube feeds: Give 40% of 24 hr requirement as glargine, 60% as rapid-acting divided equally among boluses

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