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Photo: Riccardo Venturi

GLOBAL MDR-TB ERADICATION PROGRAMS

Setiawan Jati Laksono


TB Unit

World Health Organization


Outline
1. Global TB situation
2. Global DR TB Surveillance
3. Global DR TB response
4. Five Priority action to address The
Global MDR TB Crisis
Indonesia:
Sub National data only from 2 DRS in
Central Java 2006 and East Java 2009
Estimated 1.9% among new and 12% among
Previously treated TB cases
Indonesia:
# 10th with 6,800 cases
Indonesia:
1. Only 30% of previously treated and < 1% new cases tested
2. No national wide DRS surveillance/ survey
3. Planned for 2015-2016
Indonesia: 0.03%
Indonesia: <15% tested in 2013, 30% tested in 2014
Indonesia: 44%
9 cases from Indonesia
Role of GeneXpert for TB Control Program:
• Xpert MTB/RIF should be used rather than conventional microscopy,
culture and DST as the initial diagnostic test in adults and children
suspected of having MDR-TB or HIV associated TB.
• Xpert MTB/RIF may be used as a follow-on test to microscopy in adults
and children where MDR-TB and HIV is of lesser concern, especially in
further testing of smear-negative specimens.
• Xpert MTB/RIF may be used rather than conventional microscopy and
culture as the initial diagnostic test in all adults suspected with TB.
• Xpert MTB/RIF may be used rather than conventional microscopy and
culture as the initial diagnostic test in all children suspected of having TB
• Xpert MTB/RIF should be used in preference to conventional microscopy
and culture as the initial diagnostic test in testing cerebrospinal fluid
specimens from patients presumed to have TB meningitis
• Xpert MTB/RIF may be used as a replacement test for usual practice
(including conventional microscopy, culture, and/or histopathology) for
testing of specific nonrespiratory specimens (lymph nodes and other
tissues) from patients presumed to have extrapulmonary TB
PROMOTE
REACH
DETECT
TREATMENT
RETAIN
SUPPORT
CURE
PREVENT

MATUR NUWUN
Treatment standards:
Treatment standards:

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