Product Information: Stearamide
Product Information: Stearamide
Product Information: Stearamide
Stearamide
Item No. 21087
Laboratory Procedures
Stearamide is supplied as a crystalline solid. A stock solution may be made by dissolving the stearamide
in the solvent of choice. Stearamide is soluble in organic solvents such as ethanol, DMSO, and dimethyl
formamide, which should be purged with an inert gas. The solubility of stearamide in these solvents is
approximately 22, 20, and 14 mg/ml, respectively.
Further dilutions of the stock solution into aqueous buffers or isotonic saline should be made prior to
performing biological experiments. Ensure that the residual amount of organic solvent is insignificant,
since organic solvents may have physiological effects at low concentrations. Organic solvent-free aqueous
solutions of stearamide can be prepared by directly dissolving the crystalline solid in aqueous buffers. The
solubility of stearamide in PBS, pH 7.2, is approximately 50 µg/ml. We do not recommend storing the
aqueous solution for more than one day.
Description
Stearamide is a primary fatty acid amide that is often used in the synthesis of organic chemicals and
surfactants. Levels of stearamide are reported to be up-regulated in the serum of patients with hepatic
cirrhosis.1 Thus, it may be a potential biomarker for disordered fatty acid metabolism related to fatty liver
diseases.
Reference
1. Lian, J.-S., Liu, W., Hao, S.-R., et al. A serum metabonomic study on the difference between alcohol- and
HBV-induced liver cirrhosis by ultraperformance liquid chromatography coupled to mass spectrometry
plus quadrupole time-of-flight mass spectrometry. Chin. Med. J. (Engl.) 124(9), 1367-1373 (2011).