Meiosis Poker

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The key takeaways are that meiosis produces gametes with half the normal number of chromosomes and involves two cell division phases (meiosis I and meiosis II) to achieve this.

The overall process of meiosis involves an interphase where chromosomes are replicated, then two division phases (meiosis I and meiosis II) where homologous chromosomes and then sister chromatids are separated into gametes.

The main differences between meiosis I and meiosis II are that in meiosis I, homologous chromosomes separate but sister chromatids remain attached, while in meiosis II, sister chromatids separate but homologous chromosomes have already done so in meiosis I.

Meiosis Poker

 Obtain one deck of playing cards.


 Group the cards by number (i.e. find all the 2’s, all the jacks, etc.)
 Select four groups of cards to work with (i.e. Jack, King, Queen, Ace).
 Separate the cards by color

The red suites will represent chromosomes from the mother.


The black suites will represent chromosomes from the father.
The different suites (diamonds, hearts, etc.) represent genetic information
passed on to the parents from the grandparents.

Please fill in all blanks before turning lab in. You may use external resources
(textbook/worksheets) if needed.

Begin by selecting four red cards (all different) and four black cards (all different).
Line them up in a parallel line. You should end up with four different numbers (four
will be red and four will be black).

This is the G1 phase of interphase I. Each card represents a single chromosome. This
diploid (2n) cell has four pair of chromosomes. Every cell has two copies of each
chromosome, one from each parent.

Draw a picture

Add the additional red and black cards to their corresponding pair to simulate
chromosome replication. This is synthesis of interphase I. Each group of two
represents a sister chromatid. After an additional period of growth, division begins.

Draw a picture
During prophase I of meiosis I, the homologous chromosomes are paired together
into a tetrad (group of four). Simulate this by combining all of the suites together.
The chromosomes are packed very tightly together and crossover may occur at this
time.

Draw a picture

In Metaphase I of meiosis the tetrads line up on the equator of the cell. The
chromosomes are pulled apart in Anaphase I. Sister chromatids are still attached.
Simulate anaphase I by separating the cards into two piles. Do this randomly so that
you have some red suites and some black suites in each pile. In meiosis, a cell
membrane would form around these two groups of chromosomes, forming two
haploid (1n) daughter cells.

Draw a picture

Meiosis II (occurring in each of the new cells created above)

Interphase does NOT occur (no replication)


Prophase II: chromosomes are already paired with their duplicate.
Metaphase II: Chromosomes line up on equator (center) of cell.
Anaphase II: chromosomes are pulled apart. Simulate this by separating your cards
into four piles. Note that although you have one of each kind of card, there is a
random assortment color and suites. A cell membrane would appear around each of
these cells during telophase/cytokinesis. Meiosis is now complete. Four haploid (1n)
cells have been created from one diploid cell. These cells are called gametes.

Draw a picture
Post-lab questions

1. What is the benefit of starting with two copies of each chromosome in interphase
I?

2. Why isn’t there an interphase II in meiosis?

3. What would happen if there was an interphase II of meiosis?

4. How does crossover increase genetic diversity in organisms?

5. In the playing card model of meiosis, how could crossover be illustrated?

6. What do you notice about the composition of your final groups of cards in
anaphase II of meiosis?

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