Contents Hyoscine-N-butylbromide

Indications Spasmolytic in the treatment of biliary tract disorders, dysmenorrhea, GI spasms, nocturnal enuresis or conditions
associated w/ visceral spasms.
Dosage Adult & childn >12 yr 1-2 amp by slow IV infusion/IM/SC tid-qid. Max: 100 mg daily.

Contraindications Brain lesions in childn. Cardiopathy esp cardiac arrhythmia, congestive cardiac insufficiency, coronary artery disease &
mitral stenosis. Down syndrome; esophagitis due to reflux; fever; obstructive disease of the GI tract eg achalasia &
pyloroduodenal stenosis; closed & open angle glaucoma; acute hemorrhage w/ CV instability; hepatic dysfunction;
hiatal hernia associated to reflux esophagitis; HTN; hyperthyroidism; intestinal atonia in elderly or weak patients or
those w/ paralytic ileus. Chronic pulmonary disease esp in breastfeeding infants, small childn & weak patients.
Myasthenia gravis; autonomous neuropathy; non-obstructive prostatic hypertrophy or urinary retention; propensity to
obstructive uropathy eg obstruction of the bladder neck due to prostatic hypertrophy; pyloric obstruction; renal
dysfunction; spastic paralysis in childn; tachycardia; gravidic toxemia; ulcerous colitis; xerostomia.
Special Precautions May impair ability to drive or operate machinery. Pregnancy & lactation. Childn. Elderly. Parenteral administration
before labor.
Adverse Drug Reactions Blurred or changes in vision, confusion, drowsiness, dryness of the mouth, nose or throat, fever, hallucinations,
trembling, fatigue, unusual excitement, nervousness, irritation, difficulty in breathing, vertigo, clumsiness or instability,
tachycardia, muscular weakness, burning sensation, dryness or reddening of the skin.
View ADR Monitoring Website
Drug Interactions Antacids or adsorbent antidiarrheals, antimyasthenics, cyclopropane, haloperidol, ketoconazole, metoclopramide,
opiate analgesics, KCl, CNS depressants, lorazepam.
View more drug interactions with Losil
Pregnancy Category (US
FDA)

Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other)
and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given
only if the potential benefit justifies the potential risk to the foetus.

MIMS Class Antispasmodics

ATC Classification A03BB01 - Butylscopolamine ; Belongs to the class of belladonna alkaloids, semisynthetic, quaternary ammonium
compounds. Used in the treatment of functional gastrointestinal disorders.
Poison Schedule Rx

Amoxicillin is an antibiotic that belongs to a class of antibiotics called penicillins. Common infections that amoxicillin is used to treat include infections of the middle
ear, tonsils, throat, larynx (laryngitis), bronchi (bronchitis), lungs (pneumonia), urinary tract, skin, and gonorrhea. It is important to be aware of its effect on pregnancy
and nursing mothers, as well as common side effects on the user.

BRAND NAME(S): Amoxil

USES: Amoxicillin is a penicillin-type antibiotic used to treat a wide variety of bacterial infections.

HOW TO USE: Take this medication by mouth with or without food, usually every 8 or 12 hours, or as directed by your doctor. The dosage is based on
your medical condition and response to therapy. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore,
take this drug at evenly spaced intervals. Continue to take this medication until the full-prescribed amount is finished even if symptoms disappear after a
few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection. Inform your doctor if
your condition persists or worsens.

SIDE EFFECTS: Nausea, vomiting or diarrhea may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Tell your
doctor immediately if any of these highly unlikely but very serious side effects occur: dark urine, persistent nausea or vomiting, stomach/abdominal pain,
yellowing eyes or skin, easy bruising or bleeding, persistent sore throat or fever. This medication may rarely cause a severe intestinal condition
(pseudomembranous colitis) due to a resistant bacteria. This condition may occur weeks after treatment has stopped. Do not use anti-diarrhea products
or narcotic pain medications if you have the following symptoms because these products may make them worse. Tell your doctor immediately if you
develop: persistent diarrhea, abdominal or stomach pain/cramping, or blood/mucus in your stool. Use of this medication for prolonged or repeated
periods may result in oral thrush or a new vaginal yeast infection (oral or vaginal fungal infection). Contact your doctor if you notice white patches in your
mouth, a change in vaginal discharge or other new symptoms. A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if
it occurs. Symptoms of a serious allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above,
contact your doctor or pharmacist.
 GENERIC NAME: MEFENAMIC ACID - ORAL (meff-en-AM-ick acid)

BRAND NAME(S): Ponstel

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: This medication relieves pain and reduces inflammation. It is used to treat headaches, menstrual cramps, muscle aches, dental pain and athletic
injuries.

HOW TO USE: Take with food or milk to minimize stomach upset. This medication is most effective in relieving menstrual pain if taken at the earliest
sign of pain. Take this medication with 6 to 8 ounces (180-240ml) of water. Do not lie down for at least 30 minutes after taking this drug. This medication
should not be taken for more than 7 days at a time.

SIDE EFFECTS: Stomach upset is the most common side effect. Others include nausea, loss of appetite, dizziness, drowsiness, diarrhea, and
headache. If any of these effects persist or worsen, contact your doctor or pharmacist promptly. Inform your doctor promptly if you develop: yellowing of
the eyes, fever with or without chills, vision changes. If you notice any of the following unlikely but very serious side effects, stop taking this drug and
consult your doctor or pharmacist immediately: black stools, persistent stomach/ abdominal pain, vomit that looks like coffee grounds. An allergic
reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, severe
dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor your medical history, especially of: liver or kidney disease, blood disorders, ulcers, heart disease, alcohol use, high
blood pressure, eye disease, allergies (especially drug allergies). Use caution when performing tasks requiring alertness. Limit alcohol intake as it may
intensify the drowsiness effect of this medication. This medicine may cause stomach bleeding. Daily use of alcohol, especially when combined with this
medicine, may increase your risk for stomach bleeding. Check with your doctor or pharmacist for more information. Do not take aspirin without
consulting your doctor. Check the ingredients of any nonprescription medication you may be taking since many cough-and-cold formulas contain aspirin.
Infrequently, this medication may increase the skin's sensitivity to sunlight. If this happens to you, avoid prolonged sun exposure, wear protective
clothing and use a sunscreen. Avoid sunlamps. Caution is advised when this drug is used in the elderly. This medication should be used during
pregnancy only if clearly needed. Discuss the risks and benefits with your doctor. Use of this drug in the last 6 months of pregnancy is not
recommended. It is unknown if this drug is excreted into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription drugs you may use, especially of: "blood thinners" such as warfarin,
other arthritis medication, water pills, lithium. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national
poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include severe
stomach pain, coffee ground-like vomit, dark stool, ringing in the ears, change in amount of urine, unusually fast or slow heartbeat, muscle weakness,
slow or shallow breathing, confusion, severe headache or loss of consciousness.

NOTES: Do not share this drug with others.

MISSED DOSE: If you miss a dose, take it as soon as remembered; do not take if it is almost time for the next dose. Instead, skip the missed dose and
resume your usual dosing schedule. Do not "double-up" the dose to catch up.

STORAGE: Store at room temperature away from moisture and sunlight. Do not store in the bathroom.