Vision 2030: Indian Veterinary Research Institute
Vision 2030: Indian Veterinary Research Institute
Vision 2030: Indian Veterinary Research Institute
IndianVeterinaryResearchInstitute
Izatnagar243122(UP)India
Printed: June,2011
Publishedby: Prof.M.C.Sharma
Director,IVRI
PublicationCommittee:
Dr.J.M.Kataria Chairman
Jt.Director(Research)
Dr.V.P.Singh Member
Jt.Director(Academic)
Dr.D.N.Kamra Member
HD,Div.ofAnim.Nutrition
Dr.R.Somvanshi Member
HD,Div.ofPathology
Dr.S.K.Agarwal Member
HD,Div.ofAnim.Repro.
Dr.S.V.S.Malik Member
PS,Div.ofVety.Pub.Health
Dr.K.N.Bhilegaonkar Member
PS,Jt.DirectorateofRes.
Dr.G.TaruSharma Member
HD,Div.ofP&C
Dr.RupasiTiwari Member
Incharge,ATIC
ShriKundanSingh Member
Incharge,Comm.Centre
AllRightsReserved
2011,IndianVeterinaryResearchInstitute,Izatnagar
Printedby:
M/sBytes&Bytes,Bareilly
ii
Foreword
The diverse challenges and constraints as growing population,
increasing food, feed and fodder needs, natural resource
degradation, climate change, new parasites, slow growth in farm
income and newglobal trade regulations demand a paradigm shift
in formulating and implementing the agricultural research
programmes. The emerging scenario necessitates the institutions of
ICARtohaveperspectivevisionwhichcouldbetranslatedthrough
proactive,novelandinnovativeresearchapproachbasedoncutting
edgescience.Inthisendeavour,alloftheinstitutionsofICAR,have
revised and prepared respective Vision2030 documents
highlighting the issues and strategies relevant for the next twenty
years.
Livestock sector is an integrated component of agricultural
activitiesinthecountry.Duetorisingdemandforanimalproducts
andchangingfoodpreferencesofthenextgenerationconsumers,the
Indianlivestocksectorhastoimproveitsperformance.Therefore,to
makeitprofitable,theIndianVeterinaryResearchInstituteneedsto
develop innovative alternate livestock research system. Indian
Veterinary Research Institute, Izatnagar, is a premier Institute in
veterinary science and the technologies developed by the
scientists so far to improve animal health and production are
commendable.
iii
It is expected that the analytical approach and forward looking
conceptspresentedintheVision2030documentwillproveuseful
for the researchers, policymakers, and stakeholders to address the
future challenges for growth and development of the agricultural
sectorandensurefoodandincomesecuritywithahumantouch.
(S.Ayyappan)
Secretary,DepartmentofAgriculturalResearchandEducation
and
DirectorGeneral,IndianCouncilofAgriculturalResearch
iv
Preface
The Indian Veterinary Research Institute, Izatnagar is the premier
andoneoftheoldestinstitutionsinthefieldofveterinaryandanimal
sciences.Theinstitute,throughitssignificantcontributions,hascreated
a niche in R&D on animal health and production, generation of
technology, patents and their commercialization. The institutes
valuable and significant contributions in the areas of livestock health
protection, productivity enhancement, and products technology has
played a pivotal role in ushering white revolution, which led the
countrytoattainnumberonepositioninmilkproductionintheworld.
TheinstitutehasmaderemarkableprogressinthenewIPRregimewith
patentableresearchandcommercialtechnologytransfers.Theinstitute
hasalsoattainedacknowledgedexcellenceinpostgraduateveterinary
education.
The livestock population in India has increased from 292.8 million
in 1951 to 529.7 million in 2007, which includes 199.1 million cattle,
105.3 million buffaloes, 71.5 million sheep, 140.5 million goats, 11.3
million pigs, 0.6 million horses and ponies, 0.6 million mules and
donkeys, 0.5 million camels, 0.1 million yaks, 0.26 million mithun
besides489.0millionpoultry.Presentlythecountryisproducing112.5
milliontonnesofmilk,59.8billioneggsand6.3milliontonnesofmeat.
Therefore, the livestock sector has emerged as one of the key
components of agricultural growth in India. Role of livestock sector is
crucialtofulfillgrowingfooddemandwhichisexpectedtoincreaseby
40% by 2030 and shall almost be doubled by 2050. The increased
demandoflivestockproductscanbemetbyenhancingthenumbersof
animals, improving feed utilization efficiency, adopting better
reproductivestrategiesandimprovinghealthcoveragebasedonnewer
generation biotechnological vaccines and drugs. With increase in
economicdevelopmentofthecountryandsocialobligationsofnuclear
families,theneedforcompanionanimalsiscertainlygoingtoincrease
inthecomingdecades.
Climate change is likely to affect animal health and hence
productivity directly, by altering the homeostasis and other thermo
regulatoryresponsestomaintainthethermalbalanceandindirectlyby
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affectingsupplyoffeedandfodder,increasingvulnerabilitytodiseases
and pests. In the changing scenario of increasing global trade, food
demand,manpowerrequirement,adverseimpactofclimatechangeon
productivity of livestock and threat from emerging livestock and
zoonoticdiseases,livestocksectorisgoingtofacenumerouschallenges
whichneedtobeaddressedforcompositelivestockdevelopment.
The present document, IVRI Vision 2030 after revisiting the
priorities identified earlier for research, extension, education and
development in the veterinary and animal sciences articulates the
strategiestoovercomethechallengesandtapopportunitiespertaining
to livestock development in harmony with agriculture and allied
sectors.
I am grateful to the chairman and members of the committee for
IVRI Vision2030 for discharging the responsibility of preparation of
thisimportantdocument.Thedocumentadequatelyreflectsthevision
ofavibrantinstitutioncommittedtothetaskofnationbuildinginour
mandated areas of research, extension, education, technology
developmentandtransferinlivestocksector.
[M.C.Sharma]
Director
IVRI,Izatnagar
vi
Contents
1. Preamble 1
2. LivestockScenario 2
3. IndianVeterinaryResearchInstitute 7
4. IVRI2030 8
5. HarnessingScience 10
6. StrategicFramework 18
Epilogue 20
Annexure 21
vii
viii
Preamble
In India, the livestock production and agriculture are intrinsically linked,
eachonebeingdependentontheotherandbotharecrucialfortheoverallfood
security of the people. Livestock sector plays an important and vital role in
providing nutritive food rich in animal protein, in supplementing family
income and generating gainful employment in the rural sector, particularly
among the landless, small, marginal farmers and women, and thus is a
dependablebankonhoovesintimesofneed.Withthegallopinggrowthin
human population, the demand for crop and livestock production is ever
increasing. With the concept of Food Secure India, the significance of
livestockandpoultryproductsbecomesenormous.
ThecontributionoflivestocksectortoNationalGDPvariedfrom4.86.5%
during the last two decades (Working Group Report 2006). Accelerating the
GDPgrowthinlivestocksectorto67%,whichisequitable,benefitingmainly
the small and marginal farmers and landless labourers would be a major
sourceofincomeandprovideadditionalemploymentopportunitiestopeople
intheruralareas.Asustainableandfinanciallyviablelivestockfarming,which
will generate wealth and self employment through entrepreneurship, is the
needoftheday.
Theinstituteplayedanimportantroleasanapexcentreofanimalhealth
researchinthecountrybyprovidingtechnologies,interventionsandpackage
of practices for prevention and control of highly infectious animal diseases.
The incremental benefits accrued at national level on account of specific
researchinputsmadeavailablebyIVRIinclude,freedomfromrinderpestsince
1995; achieving zero status of CBPP; rapid response, timely control and strict
vigil on avian influenza; development of indigenous live modified vaccine
against PPR and a CELISA kit for PPR antibody detection and sandwich
ELISA kit for PPR antigen for control programme and seroepidemiology; a
safepotentlowvolumesaponifiedHSvaccinetominimizelossesonaccountof
morbidity and mortality. In the changing scenario of increasing global trade,
ever increasing food demand due to population pressure, adverse impact of
climatechangeonproductivityandreproductionoflivestockandthreatfrom
emerging, reemerging and transboundary livestock and zoonotic diseases,
livestocksectorisgoingtofacenumerouschallenges.
Vision2030documentoftheIVRIisablueprintforfutureprogrammesof
science,education,technologyandservices,whichhavebeenformulatedafter
revisiting the priorities identified earlier for research, education and
development in the veterinary and animal sciences under National
AgriculturalResearchSystem.
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IndianVeterinaryResearchInstitute
LivestockScenario
Globalfooddemandiseverincreasingandexpectedtobedoubledbythe
year 2050 due to exponential increase in population while the agricultural
productivity is declining, largely due to shrinking of resources particularly
cultivable land. Under such a situation, role of livestock sector to fulfill
growing food demand is of paramount importance in terms of nutritional
securityandemploymentgeneration.Thelivestocksectorhasemergedasone
ofthekeycomponentsofagriculturalgrowthindevelopingcountries.Itplays
a critical role in the socioeconomic development and welfare of Indias rural
populationnotonlyasasourceoffood(milk,meatandegg)butalsodraught
power,manure,hidesetc.Distributionoflivestockwealthismoreegalitarian
compared to land. Hence from the equity and livelihood perspective, it is
considered an important component in poverty alleviation programmes. The
Indianlivestocksectoristheendeavorofsmallholdersandisacenturiesold
traditionandover70%ofruralhouseholdsdependuponlivestockfarmingfor
supplementaryincome.Thissectorishighlygendersensitiveandabout90%of
the activities related to care and management of livestock are carried by
familys women folk. As a result of gradual transition from subsistence to
market system, the economic dimensions of livestock keeping have gained
significance.Thevalueofoutputfromlivestockandfisheriessectorstogether
at current prices is about `4,08,386 crore during 200910, which is about 29.7
percentofthevalueofoutputof`13,76,561crorefromagricultureandallied
sectors. Livestock in total contributes 3.93%(`2,41,177 crore) of national GDP
and 22.14% of the agricultural GDP. The contribution of milk in national
economy is higher (` 2,28,809 crore) than paddy (`1,35,307 crore), wheat
(`1,03,226 crore) and sugar cane (`37,366 crore). Animal husbandry sector
provideslargeselfemploymentopportunitiesandabout6.7%ofworkforcein
ruralareasisengagedinthissector.
Livestockresources
India possess 530 million livestock, which includes 199.08 million cattle,
105.34 million buffaloes, 71.5 million sheep, 140.5 million goats, 11.34 million
pigs, 0.61 million horses and ponies, 0.57 million mules and donkeys, 0.52
million camels, 0.08 million yaks, 0.26 million mithun besides 489 million
poultry(18thLivestockCensus,2007).Indiaranksfirstwithrespecttobuffalo,
second in cattle and goats, third in sheep and fifth in poultry population in
comparison to the world livestock and poultry population. Total Livestock
populationinIndiahasincreasedfrom292.8millionin1951to530millionin
2007attherateof1.06%.Incontrast,populationofhorsesandponies,camels,
pigs,mulesanddonkeyshasshownatrendofnegativegrowth.
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Contributionoflivestock
Livestock sector not only provides essential protein and nutrition to
humandietthroughmilk,eggs,meat,rawmaterial/byproductssuchashides
andskin,blood,boneandfatetc.butalsoplaysanimportantroleinutilization
of nonedible agricultural byproducts. India continues to be the largest
producer of milk in the world (15.70% of total milk) having 112.5 million
tonnes production with 263 g/day/capita availability (200910). The milk
production followed quadratic trend during 197980 to 200910. If the same
trendcontinuesthemilkproductionwillreachtoalevelof135milliontonnes
by201516.Crossbredcattle,indigenouscattle,buffaloesandgoatscontribute
about22.86,20.25,53.37and3.52%,respectivelytototalmilkproduction.The
averagedailymilkyieldofindigenouscattleisquitelow(2.1kg)ascompared
to crossbred cattle (6.9 kg) and buffalo (4.6 kg). So far the fullest production
potential of our livestock could not be tapped and there isan urgent need to
enhance the levels through genetic improvement along with modern
husbandryandhealthpractices.
Poultry development in the country has shown steady progress over the
yearsbyproducing59,844millioneggsin200910asagainst1,832millioneggs
in 195051 with the availability of 51 eggs per head per year in 200910 in
contrast to 5 eggs in 195051. The egg production in India has witnessed an
exponential growth during 197980 to 200910 and is expected to touch the
levelof83,200millioneggsbytheyear201516.
Indiaproducedabout63lakhtonnesofmeatintheyear2009against16.96
lakh tonnes in 1961 with an annual growth rate of 2.01%. Buffalo contributes
maximum (33.66%) followed by cattle (20.90%) and poultry (17.13%) in the
total meat production of the country. The total meat production has shown
logistictrendwithanannualgrowthrateof5.4%.
Duringtheyear200910,thetotalwoolproductionwas43.2millionkgas
comparedto27.5millionkgin195051.Indiacontributed2.2%oftotalworlds
wool production and Rajasthan is the highest contributor (29%) to the wool
productionofthecountry.
Among the animal byproducts, 9.17 lakh tonnes of hides and 1.89 lakh
tonnesskinswereproducedduringtheyear200809,whichis10.53and6.36%,
respectively,ofthetotalworldproduction.
Livestockproduction
Indian cattle and buffalo milch breeds have inherent capability of heat
tolerance,resistancetodiseasesandabilitytothriveunderextremenutritional
and environmental stress. Considering the importance of these indigenous
breedsinthenationaleconomy,Governmentisundertakingseriousstepsfor
their development and conservation. The cattle and buffalo genetic resources
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ofIndiaarerepresentedby30indigenousbreedsofcattleincludingRathi,Gir,
Kankrej, Tharparkar, Sahiwal, Deoni, Halliker and Hariana and 10 breeds of
buffaloesincludingMurrah,Jaffarabadi,MehsanaandSurti.Conservationand
propagation of these indigenous breeds using modern biotechnological tools
includingartificialinsemination(AI)needstobefocusedinordertogradually
replace our huge nondescript population to augment productivity. This
would require bringing maximum breedable bovine population under the
umbrella of artificial insemination. The essential prerequisites would be
owners awareness programmes and strengthening the AI infrastructure. The
statisticsrelatedtoprogressofAIgivessatisfactionthatsemenproductionin
the country has increased from 22 million straws (19992000) to 50.52 million
straws (200910) and the number of inseminations has increased from 20
millionto44million.Theoverallconceptionratehasalsoincreasedfrom20to
35%,however,infertilityneedstobekeptatbareminimumasitcontinuesto
beamajorbottleneckintherapidgeneticimprovementbesidescausinghuge
economiclosses.
Adequateavailabilityoffeedandfoddertolivestockisvitalforincreasing
the productivity and also for sustaining the initiatives taken for genetic
improvement.Optimumandefficientutilizationoffeedandfodderresources
holdsakeyforsuccessfulcommerciallivestockproduction.Alargegapexists
betweendemandandsupplyoffeedandfodderinthecountry.
Livestockhealth
Besides management, animal health plays a major role in the progress of
livestock industry. Occurrence of diseases causes heavy economic losses in
terms of livestock health and production. Introduction of exotic breeds have
increasedtheincidenceofdiseasesespeciallyFootandMouthDisease(FMD),
Haemorrhagic Septicaemia (HS), pestedespetits ruminants (PPR), Brucellosis,
Mastitis, Blood protozoon diseases etc. Unless we make sincere efforts to
controlandmanagecommondiseaseslikeFMD,HS,mastitisandBrucellosis,
we will be far away from achieving the targeted milk production of 160170
milliontonnesby2030.
TheeconomiclossduetoFMDistremendousasitcausesdeathofyoung
animals, reduction in milk yield and quality and quantity of meat, abortion,
infertilityandpoorqualityofsemen.FMDalsorestrictsthepossibleexportof
livestock and livestock products. In India alone 902 outbreaks of FMD
occurred during 200910 affecting more than 26,500 animals. HS in cattle,
buffaloes, sheep, goats and pigs accounted for 296 outbreaks. Mastitis is a
multi factorial problem of dairy animals affecting milk production adversely.
The loss caused by mastitis is due to reduced milk production, cost of
treatment and culling of animals. As per annual report of the Department of
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Vision2030
AnimalHusbandry,DairyingandFisheries,morethan26,300animalsmostly
cattlewereaffectedbymastitisintheyear200910.
The small ruminants like sheep and goats play critical role in socio
economicdevelopmentoftheruralpoor.Theseanimalsalsosufferwithmany
diseases of different origin, most importantly PPR and bluetongue. The
economiclossduetoPPRismainlythroughmortalityofadultpopulationand
poor carcass quality. During the year 200910, 184 outbreaks of PPR and 73
outbreaksofbluetonguehaveoccurredcausingheavyeconomiclosses.
Pig is an important livestock species, which plays crucial role in the
livelihoodinnortheasternstatesofthecountry.Thereareseveraldiseaseslike
FMD, swine fever and HS, which cause severe economic loss to the pig
industry.Duringtheyear200910,136outbreaksofswinefeverhaveoccurred
causingheavymortality.
Poultry industry is growing exponentially but it is under constant threat
fromvariousdiseaseslikeavianinfluenza,infectiousbursaldisease,Newcastle
disease (ND), chronic respiratory disease (CRD), salmonellosis, fowl pox and
coccidiosisetc.NDhasbeenthemostdangerouswithrespecttoincidenceand
death occurrence. During the year 200910 alone, 412 outbreaks of ND, 122
outbreaksoffowlpox,222outbreaksofCRDand348outbreaksofcoccidiosis
haveoccurredcausingheavyeconomiclossduetomortality,poorproduction
andcostinvolvedintheircontrol.
Climatechangeandlivestock
Oneoftheenvironmentalthreatswhichourplanetfacestodayistheglobal
climatechange.Thesechangesareharmfultobothhumanbeingsandanimals.
InterGovernmentalPanelonClimateChangehasprojectedthatbytheendof
this century global earth temperature is likely to increase by 1.84.00C. This
global climate change could potentially lead to scarcity of water and food
resources and may also cause spread of infectious diseases and heatrelated
deaths.Further,projectedclimaticchangesareexpectedtoincreasetherisksof
vectorborne and other diseases leading to change in pattern of disease
transmission. Due to increase in temperature and change in rainfall pattern,
thevectorpopulationswillbeexpendingtounforeseenareas(higheraltitude
or temperate zones). Bluetongue in Europe and Rift Valley Fever in goats in
East Africa are two documented examples of increased vectorborne disease
risk in goats associated with climate change. Further, microbial agents and
their vectors may be sensitive to factors such as temperature, humidity,
precipitation, surface water, wind and changes in vegetation and bound to
have an impact on heatrelated mortality and morbidity. It has been
hypothesized that under climatic variability and change, our livestock
populationisboundtobeaffectedbyemergingandreemerginginfections.
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IndianVeterinaryResearchInstitute
Technologicaladvancement
Recent advancement in molecular biology, biotechnology and
nanotechnology has revolutionized the field of animal disease diagnosis and
prophylaxis.Nowpensideandsensitiveserodiagnosticsusingsyntheticand
recombinantantigensareavailableformanydiseases,whichareveryusefulin
serosurveillance. Further, nucleic acid based diagnostics like PCR, Real time
PCR, probe based diagnostics for detection of important diseases like IBR,
FMD,HS,swinefeveretcarenowbeingusedroutinely.Manylaboratoriesare
working towards developing high throughput chip based diagnostics for
important diseases of livestock. Biotechnology/nanotechnology developments
have also revolutionized the field of vaccinology including vaccine delivery
system. Recombinant vaccines are being developed that have the advantages
ofbetterimmunityandlongshelflife.Biotechnologytoolsarealsobeingused
toimproveourindigenousbreedsusingtransgenicandstemcelltechnology.
Futureperspectives
Although animal sector is growing at satisfactory level, but to meet the
national demand of animal products, concerted efforts in terms of better
health, feed and fodder availability, and proper breeding management are
required to exploit this sector maximally. Efforts are to be made to conserve
and perpetuate our valuable germplasm, which are adaptable to adverse
climaticconditionsandresistanttovariousendemicdiseases.Livestocksector
holdskeytoovercomethefutureunemploymentproblemsinruralyouth.
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Vision2030
IndianVeterinaryResearchInstitute
The Indian Veterinary Research Institute (IVRI), Izatnagar established on 9th
December 1889 as Imperial Bacteriological Laboratory, Pune is the premier
Institution for veterinary research and education. IVRI is the oldest institution
governed by Indian Council of Agricultural Research, which is an autonomous
organization under the Department of Agricultural Research and Education,
MinistryofAgriculture,GovernmentofIndia,NewDelhi.Theinstitute,throughits
significantcontributions,hascreatedanicheforitselfinR&Donanimalhealthand
production, technology generation, patents and technology comercialization. The
institute presently has 4 campuses, 3 regional stations and functions through 20
researchdivisions,besideCentresforAnimalDiseaseResearchandDiagnosisand
WildlifeConservation,ManagementandDiseaseSurveillanceandothersupporting
centralfacilities.TheinstituteacquiredDeemedUniversitystatusin1983andtoday
the university offers Masters programme in 22 disciplines, PhD programme in 20
disciplines and National diploma courses in 9 disciplines as a part of continuing
education for field veterinarians, besides several shortterm specialized training
coursestotheprofessionalsandvocationaltrainingstothefarmers.
Inits122yearsofeventfuljourney,theinstitutehasbeenthetorchbearerfor
pioneering research and quality postgraduate education in veterinary and animal
sciences. The institutes valuable and significant contributions in the areas of
livestock and poultry health protection, productivity enhancement, and products
technology have been highly rewarding to the nation. The creditable work carried
out at the institute on the promotion of integrated programmes of health care,
genetic improvement and nutrition has played a pivotal role in ushering white
revolution,whichledthecountrytoattainnumberonepositioninmilkproduction,
fourth in egg production and fifth in broiler production in the world. The
technologiesdevelopedbytheInstituteintheareaofanimalhealthhavehelpedto
protect our livestock and poultry against scourge of dreaded diseases and
infections.
Keepinginviewthepresentandfutureneeds,theinstituteisembarkingupon
extensive programmes of research in frontier areas to improve animal health and
productivity. In the scenario that is going to unfold, the institute will have the
followingmandate.
Mandate
1. To conduct research, provide postgraduate education and transfer of
technologiesinallareasofveterinaryandanimalscienceswithemphasis
onanimalhealthandproduction.
2. To act as National Referral Centre for veterinary type cultures, disease
diagnosis,biologicals,immunodiagnostics,etc.
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IndianVeterinaryResearchInstitute
IVRI2030
IndianVeterinaryResearchInstitutewiththeexcellenceinfrontierareasin
veterinary and animal science is ready and geared up to play pivotal role in
addressingthenationalgoalsofimprovedproductivity,profitability,stability
and sustainability in livestock sector. The institute will strive hard with the
concerted efforts to be global leader in veterinary science for the animal and
humanwelfare.
Vision
Striving for excellence in innovative research, human resource
development,technologygenerationandtransferforimprovedanimalowners
andloverswithacknowledgedleadershipamongtheworldnations.
Mission
Undertaking pioneering research in veterinary and animal sciences with
holisticapproach,promotinghighqualityeducationandtraining,developing
systems and technologies for better animal health care and production and
their transfer to endusers, functioning as an effective instrument for
nutritionalsecurity,povertyalleviationandruralconstruction.
Focus
Inordertokeeppacewiththesocietysneedsandscientificadvancesinthe
areaoflivestockandpoultryhealthandproduction,andforrealizationofthe
envisioned goals and to accomplish the mission of the IVRI, the major thrust
areaswillbe:
N Improving animal health by development of diagnostic kits, vaccines,
biologicals, natural and synthetic drugs, methodologies for surgical
disorders, biosafety measures for handling pathogens and recombinant
organisms,strategiesforeffectivecontrolofzoonotic,exoticandemerging
diseases, vectors and measures for combating toxicity and residue
problems.
N Creating excellence in clinical sciences with capacity building for super
specialitiesinmedicine,surgery,gynaecologyandobstetrics.
N Developmentofmoderndiagnosticmethodsandtherapeuticmanagement
ofnoninfectiousdiseaseslikemetabolicanddeficiencydiseases.
N Gainful utilization of potential of frontier areas like stem cells,
pharmacokinetics and nutrigenomics, transgenic animals, proteome
analysis, biosensor applications, targeted nanodelivery of drugs, sports
spacemedicine,IVFETT,etc.
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HarnessingScience
Indian Veterinary Research Institute continues to play a major role in
harnessingveterinaryandanimalscienceresearch,educationandextensionfor
the allround development of livestock sector, thus making the country self
reliantinimmunobiologicals,otherproductsandservices.Changingnatureof
livestock service delivery, growing economy, manpower requirements and
opportunities in the private sector provide both push and pull dynamics for
compositelivestockdevelopment.Amidsttheseglobalchangesandchallenges,
it is time that we reassess strengths, weakness and opportunities to fully
harnessthepowerofsciencetoaccomplishthesetgoals.
Developmentandimprovement
of immunoprophylactics for
effective control of existing,
emergingandexoticdiseasesof
animalsandpoultry
The disease control scenario in
the country is becoming complex
with the intensification of the
livestock and poultry production,
import of germplasm, unrestricted Goataffectedwithpestedespetitsruminants
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Vision2030
movementoflivestock,changesinecosystemduetoclimatechange,selection
pressure on the pathogens and emergence of new variants. This warrants
improvement of the existing vaccines and/or vaccination schedule and
development of new generation vaccines including subunit, genetically
engineered, edible, synthetic and combination vaccines with concurrent
development and improvement in vaccine delivery systems through use of
nanoparticle, adjuvants, liposomes, escheriosomes and immunomodulators.
The availability of improved, potent and efficacious vaccines meeting
international standards against major prevalent diseases will enable better
management,containmentandcontrolofthediseases.Thiswillensurebetter
preparedness to meet the SPS requirements for the international trade and
rapiddevelopmentofsustainablelivestockindustry.
Protectingandpromotinghumanhealth
The world today is plagued
AdVNtreated
with many infectious diseases, of
which the zoonotic diseases
contribute to the pool of emerging
diseasesintertransmissiblebetween
animals and human beings. There Control
have been serious outbreaks of
zoonotic diseases like avian and
swine influenza, Crimean Congo
haemorrhagic fever, Japanese
encephalitis, Nipha virus disease FluorescentfocireductioninBHK21cells
transducedwithadenovirusencodingsiRNA
and food borne infections and
againstRVNgeneofrabiesvirus
intoxications whose endemicity,
reservoirandseasonalpatterns,etc.areamatterofgrowingconcern.Further,
toxicologicalaspectsofresiduesofdrugs,pesticides,environmentalpollutants
andotherxenobioticsareofgreatconcerntobothlivestockwealthandhuman
life,aswellas,forprovidingwholesomefoodforhumanbeingsandanimals.
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Harnessingthepowerofcuttingedgetechnologyresearch
The biological research is
flooded with continuous flow of
dataemanatingfromtheconfluence
oftechnologicaladvancesinprotein
andnucleicacidanalyses,aswellas
imaging advances of cell biology.
Information at the level of genome,
transcriptome, proteome and
metabolome which provide distant
data sets for understanding
biological function of all living
Bonemarrowstemcells
organisms including animals and
thebiologicalagentsactingaspathogens.Theresearchinthefrontierareaslike
stem cells, pharmacokinetics and nutrigenomics, transgenic animals,
proteomeanalysis,siRNAtechnology,biosensorapplications,targetednano
delivery of drugs, IVFETT, etc. will be gainfully utilized for strengthening
researchefficiency.
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Vision2030
Developmentandstrengtheningbiosafetycapabilities
Anumberofanimalpathogensifnothandledproperlyinthelaboratories,
are likely to escape into the environment and may cause outbreaks. Some of
the animal pathogens, which are zoonotic in nature, may adversely affect
human health. The guidelines from concerned departments of Govt. of India
stipulateappropriatebiosafetyprecautionstobetakenwhilehandlinganimal
pathogensandrDNAproducts.Itis
therefore, necessary to develop and
strengthen the biosafety measures
(laboratorieshandlingriskgroupIII
and IV pathogens) at the institute
and modernize the laboratories
engagedinproductionofveterinary
biologicals, quality testing and
diagnosticserviceswithappropriate
GMP/GLP/biosafety compliant Biosafetylaboratory
facilitiesunderthenewSPSregime.
Strategiesforclimatechange
Climate change is likely to aggravate the stress condition in livestock,
thereby adversely affecting productivity and reproductive efficiency. It will
also have direct or indirect influence on the susceptibility of animals to
diseases as well as changing pattern of disease occurrence, especially vector
borne diseases. With the support from policy framework, the institute would
like to take lead role in mitigating the adverse effect of climate change by
strengthening research on allele mining for abiotic stress management,
geographic information system (GIS) based pathogenspecific bio
climatographs for reliable disease forecasting and monitoring and
physiological,nutritionalandmanagementalstrategies.
Geneticstudiesondiseaseresistanceindomesticspeciesoflivestock
Many diseases of domestic animals cannot be prevented/ eradicated by
conventional measures of hygiene and prophylaxis. Better solution to these
problemslieinidentificationandpropagationofgeneticallyresistantanimals
against bacterial, viral, parasitic, metabolic and reproductive diseases/
disorders.Manyofthesediseasescanbegeneticallycontrolled.
DNA markers for disease resistant genes and the ability to diagnose
specific genotypic markers that correlate with susceptible and resistant
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Productionoflaboratoryanimals
Production of laboratory animals has been one of the important
programmes in any biological research institution. There is a need to
intensify the production facilities for conventional laboratory animals and
create infrastructure, expertise, training needed for production of SPF
rodents,rabbits,chicks,andchickenembryos.DesignatedABSL4facilities
andinfrastructurebiosecurity,isolatorsandquarantinefacilitiesarealsoto
be established. Studies on inheritance pattern of fiber in mutant stock of
Angora rabbits and selection for genetic improvement in New Zealand
Whiterabbitsneedtobecarriedout.
Livestockproductionmanagement
Livestockmanagementalissues,specificallyrelatedtofeeding,housing,
behaviour,adaptationetc.areofutmostimportanceforimprovement ofthe
health, productivity and welfare of animals. Therefore, development of
managementalnormswithrespecttofeeding,breeding,housingandhealth
careneedtobeundertakenincattle,buffaloes,sheep,goats,pigsandother
livestock species for enhancing growth, reproduction and production
performance. Understanding animal behaviour and development of
appropriate modules are also required to enhance production and to
promoteanimalwelfare.Inmodernintensivemethodofanimalproduction,
modernization of livestock production units through electronic
identification, automation of various livestock farm activities including
livestock shelters and fodder production will have to be undertaken for
efficientutilizationofavailableresources.
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make them usable for the feeding of animals, monitoring and surveillance
oflivestockdiseasesspecifictotheregion.
Optimizednutritionforhealthyandimprovedlivestockproduction
Animalnutritionplaysavitalroleinlivestockproductionasitaccountsfor
morethan70%oftotalrecurringcostofproduction.Inadditiontomeetingthe
nutrientrequirementsofanimals,thereisaneedforprecisionfeedingtoavoid
wastageofnutrientsandmakingthelivestockproductionmoreeconomicand
ecofriendly.Considerableamountofmethaneisproducedbythelargeanimal
populationofthecountry.IndiabeingasignatorytoKyotoProtocol,isbound
to check release of green house gases to avoid further increase in global
warming.Therefore,effortswillbefocusedtoreducemethaneemissionbythe
ruminantsusingimprovedfeedingpracticesandtechnologies.
To make the livestock production self sustaining, economic and eco
friendly nutritional strategies viz., the search for newer unconventional feeds
including herbal and microbial feed additives, organic mineral supplements
for better bioavailability and improved health and production of designer
livestock products by modifying the rumen microbes using conventionaland
advancedbiotechniqueswouldbetakenup.Newerfeedsupplementsforpet
and domesticated animals ensuring their health, immunity and productivity
willbeaddressed.Specificdietfordifferentdiseaseconditionsoflivestockand
petanimalswillalsobedeveloped.
Basicandstrategicresearchforphysiologicalcapacitybuilding
The production efficiency of meat, milk, eggs and wool, the end
productsofphysiologicalprocessesinthebody,aregreatlydictatedbythe
integrated cell structure, function and gene expression. Environment and
climateasexternalcomponentsimpingethesephysiologicalfunctions,and
change in climate is likely to affect the animal health and production
directly (homeostasis and thermo regulatory responses) or indirectly
(supply of feed and fodder and increasing vulnerability to diseases and
pests).
To achieve superior and healthy livestock productivity, physiological
responses, genes and allele mining associated with abiotic stress tolerance
and immune competence under natural and controlled climatic stress
conditionsinlivestockadaptation,facilitationandameliorationofstressvia
newer generation biotechnological approaches are important areas which
needresearchattention.Applicationofgenebasedphysiologicalstrategies
in augmenting animal production and performance in farm animals,
modulationofphysiologicalfunctionsthroughnutrients,impactofdietary
energy level and body condition score on physiological resilience,
identificationofnovelgrowthpromoters,explorationofappliedmolecular
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Developmentofqualityandsafelivestockproducts
Therapidurbanizationandchangeinhumanlifestyledemandsconsumer
friendlylivestockproductssuchaslowcalorie,lowcholesterol,lowsalt,high
dietary fibre and fortified or fermented products suiting to their health
requirements. In the WTO era, wholesomeness parameters related to
microbiological standards, handling, processing practices, temperature abuse
indicatorsandresidualanalysisneedtobeaddressed.Thiscanbeachievedby
assessment of risks and development of rapid screening methods including
biosensors, development of simple technologies for quality enhancement of
meat from spent animals, field kits for meat speciation, sex identification,
protocolsforfoodsafetyassuranceandqualitycontrolwithspecialemphasis
on TQM, HACCP and productiontoconsumption approach. Newer
technologies for valueaddition, biopreservation, ecofriendly packaging and
quality control are required for effective utilization and improvement in
qualityaswellasshelflifeofmeatandmeatproducts.
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Humanresourcedevelopment
The institute has immensely contributed to higher veterinary education
andtraininginthecountryforoverelevendecades.Theexcellenceinresearch
and higher education achieved by the institute, received accolades nationally
and internationally. A vibrant academic atmosphere in IVRI would be
maintainedbya)strengtheningnicheareastowardsglobalcompetitiveness,b)
introducingnewspecializedcoursesintheemergingareaslikebiosecurityand
biosafety,bioengineeringandbioinformatics,sanitaryphytosanitarymeasures,
business and trade management, forensic sciences, biodiversity conservation,
information and communication technology, IPR management, etc. and c)
reorienting academic programmes, teaching methodologies (Multimedia
modules and ICT tools) and course curricula to meet emerging challenges.
Apart from the HRD services to the nation, the scientists are frequently
deputedtootherinstituteswithinandoutsidethecountryforimprovingtheir
knowledgeandscientificskills.
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StrategicFramework
Thefollowing5pointstrategywouldbeadoptedtoaccomplishthevision
andthegoalsoftheIndianVeterinaryResearchInstitute,andhencetoenhance
efficiency and effectiveness of veterinary research towards achieving better
healthandproductionoflivestock(AnnexureI).
1. Impetusonresearchonanimalhealth
N Developspecificandsensitiveserological,molecular,chipandbiosensor
based diagnostics for important bacterial, viral, fungal and parasitic
diseases.
N Develop new vaccines specially nuclear vaccines with appropriate
adjuvantandbetterdeliverysystem.
N Apply molecular tools for epidemiological studies on animal pathogens,
zoonotic diseases and drug resistance organisms/ anthelmintic resistant
parasites.
N Strengthen basic research on host pathogen interaction, functional
genomicsofpathogensandmucosalimmunity.
N Surveillance and diagnosis of diseases and develop methodologies for
forecastingtheincidence,mortality,productionandeconomiclosses.
N Emphasisondevelopingexcellenceandspecialityinclinicalservices.
N Pathology, pathogenesis and management of toxic, deficiency and
metabolicdiseasesofdomesticandpetanimals.
N Studiesontheeffectsofenvironmentalpollutantsandotherxenobioticson
animal health and production and development of strategies to counter
them.
N Geneticstudiesondiseaseresistanceinlivestock.
N Optimizednutritionforhealthyandimprovedlivestockproduction.
N FoodsafetyassuranceandqualitycontrolwithspecialemphasisonTQM,
HACCPandemergingpathogens.
N Newertechnologiesforvalueaddition,biopreservationandimprovement
inqualityaswellasshelflifeofmeatandmeatproducts.
2. Emphasisonqualityeducationforcompetenthumanresource
N Reorient academic programmes, teaching methodologies and course
curriculatomeetemergingchallenges,givingmoreemphasisonbusiness
oriented approach, utilizing multimedia modules for instructions, online
examinationsandnetworkbasedinstructionsanduseofdistancelearning
teachingmethodology.
N ManpowerplanningandimprovingHRDcompetence.
N Introduce new courses in the emerging areas like biosecurity and bio
safety, bioengineering and bioinformatics, livestock business
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5. Infrastructuredevelopment
N Development of modern veterinary polyclinic with clinical super
specialities.
N Biosafetyandbiosecurityfacilities.
N GMP/GLPcompliantlaboratories.
N Stateofartcommoninstrumentationfacility.
N Establishment of multimedia with audio visual facilities for disease
forecastingthroughradio,T.V.etc.
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Epilogue
IndianVeterinaryResearchInstituteismarchingaheadwithrenewedzeal
and is committed to make concerted efforts in veterinary and animal science
research, education and extension for sustained development of livestock
sector.
Theenvisagedreinforcementofresearchonqualitylivestockhealthcareis
expectedtohaveadirectanddecisiveimpactonanimalhealthandproduction
which influences human health favourably. The balanced diet to all human
population,withtheminimumrequirementforanimalproteinperpersonper
daywillbeprovidedtorealizetheconceptofFoodSecurity.
For effective implementation of the identified programmes, linkages will
befosteredwithnationalandinternationalR&Dinstitutionsononehandand
with the beneficiaries/farmers/industries through collaborative research,
consultancy, contract research and contract service, training, extension
activities,etc.ontheother.
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Annexure1:Strategicframework
Performance
Goal Approach
measures
Earlyandaccurate Develop specific and sensitive serological, Reduced
diagnosisof molecular, chip and biosensor based morbidityand
diseasesof diagnostics for important bacterial, viral, mortality of
livestock. fungalandparasiticdiseases. animals.
Apply molecular tools for epidemiological Reduced
studies on animal pathogens, zoonotic economic loss
diseases and drug resistant organisms/ tothefarming
anthelminticresistantparasites community.
Preventionand Surveillance and diagnosis of animal and Reduction in
controlof poultrydiseases. the incidence
bacterial,viral, Develop methodologies for forecasting the of diseases,
fungaland incidence,mortalityandmorbiditypattern hencereduced
parasiticdiseases. ofdiseaseconditions. morbidity,
mortality and
Strengthenbasicresearchonhostpathogen
better animal
interaction, functional genomics of
health.
pathogensandmucosalimmunity.
Conducting basic and applied research to
understand the genetic basis of hosts
resistance/ susceptibility against infectious
& parasitic diseases and reproductive
disordersindifferentlivestockspecies.
Develop vaccines with markers,
appropriate adjuvant and better delivery
system like nanodelivery against animal
diseases.
Achieving Development of nanoparticle based drug Earlyrecovery
excellencein deliverysystemandsafetyofnanoparticle from diseases,
clinicalservices. to overcome the difficulties in leading to
chemotherapy. reduced
Developmentofsafeandeffectivemodern convalescent,
therapeutics like nanomedicine and stem less cost of
celltherapy. treatment and
less economic
Developmentofdiagnosticandtherapeutic
loss to the
modalities for production, deficiency,
farmers.
toxicologicalandnoninfectiousdiseases.
Development of facility and expertise in
the areas of dental, ophthalmic,
neurosurgeryandcardiovascularsurgery.
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