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    Research Impediments

    Uploaded by

    Don Nestor Razon Jr.
    The document summarizes research being conducted to develop an oral tablet dosage form containing the pigment nasunin extracted from eggplant peels. The researchers extracted nasunin using methanol and water filtration and tested the extract using HPLC. They also conducted studies on the preformulation of nasunin tablets and potential interactions with excipients, as well as toxicity studies using an unspecified animal species to identify any toxic effects of the drug product. The research is being performed at the University of Santo Tomas in Manila from 2016-2018.

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    Research Impediments

    Uploaded by

    Don Nestor Razon Jr.
    543 views1 page
    The document summarizes research being conducted to develop an oral tablet dosage form containing the pigment nasunin extracted from eggplant peels. The researchers extracted nasunin using methanol and water filtration and tested the extract using HPLC. They also conducted studies on the preformulation of nasunin tablets and potential interactions with excipients, as well as toxicity studies using an unspecified animal species to identify any toxic effects of the drug product. The research is being performed at the University of Santo Tomas in Manila from 2016-2018.

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    The document summarizes research being conducted to develop an oral tablet dosage form containing the pigment nasunin extracted from eggplant peels. The researchers extracted nasunin using methanol and water filtration and tested the extract using HPLC. They also conducted studies on the preformulation of nasunin tablets and potential interactions with excipients, as well as toxicity studies using an unspecified animal species to identify any toxic effects of the drug product. The research is being performed at the University of Santo Tomas in Manila from 2016-2018.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    543 views1 page

    Research Impediments

    Uploaded by

    Don Nestor Razon Jr.
    The document summarizes research being conducted to develop an oral tablet dosage form containing the pigment nasunin extracted from eggplant peels. The researchers extracted nasunin using methanol and water filtration and tested the extract using HPLC. They also conducted studies on the preformulation of nasunin tablets and potential interactions with excipients, as well as toxicity studies using an unspecified animal species to identify any toxic effects of the drug product. The research is being performed at the University of Santo Tomas in Manila from 2016-2018.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
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    Research impediments

    The nasunin pigment was extracted from the exocarp by maceration and filtration,

    dried, treated with methanol and distilled water, distilled again by using Sep-Pak C18 that

    is activated with methanol and distilled water and resuspended in a solution of

    trifluoracetic acid (TFA). The outcome of the extraction was tested using High

    performance liquid chromatography (HPLC). The extract of Solanum melongena L. peels

    was filtered by using a Sep-Pak C18 cartridge, obtaining a first elution in methanol

    (Solution B colored in brown) and a second in distilled water (Solution A colored in

    purple). Both eluates were dried and weighed. Were obtained, respectively, 0.6523 grams

    for the dry residue A and 0.2110 grams for the dry residue B. The two samples were

    resuspended and analyzed by HPLC (Zhang et al., 2004; Sadilova et al., 2006, as cited in

    Gallo et al., 2014).

    The study is conducted at the University of Santo Tomas at Espana Blvd, Sampaloc,

    Manila, Metro Manila during the 2nd semester of School year 2016-2017 up to the 1st

    semester of school year 2017-2018.

    The research is focused on the preformulation of Nasunin into an oral dosage form,

    tablet, and to determine the possible reactions of Nasunin with the excipients that are

    used to develop the dosage form. Toxicity studies are also included in the research to

    recognize any toxic effects produced by the drug product. The drug product was tested

    on ___(animal species to be used I not yet known)___ from ___(place where to buy

    animal not yet known)____.

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