Scribd Logo
Upload

Welcome to Scribd!

  • 28 views

    Pre-mRNA: 5' Capping Polyadenylation Intron Splicing

    Uploaded by

    Kayoung Heo
    This document summarizes pre-mRNA processing, which includes 5' capping, intron splicing, and polyadenylation. Introns are removed from pre-mRNA and exported from the nucleus as mature mRNA. These processing steps protect the mRNA from degradation and allow for translation in the cytoplasm.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    Pre-mRNA: 5' Capping Polyadenylation Intron Splicing

    Uploaded by

    Kayoung Heo
    28 views1 page
    This document summarizes pre-mRNA processing, which includes 5' capping, intron splicing, and polyadenylation. Introns are removed from pre-mRNA and exported from the nucleus as mature mRNA. These processing steps protect the mRNA from degradation and allow for translation in the cytoplasm.

    Original Description:

    Mindmap of post-transcriptional modification

    Original Title

    post-transcriptional modification

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    This document summarizes pre-mRNA processing, which includes 5' capping, intron splicing, and polyadenylation. Introns are removed from pre-mRNA and exported from the nucleus as mature mRNA. These processing steps protect the mRNA from degradation and allow for translation in the cytoplasm.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    28 views1 page

    Pre-mRNA: 5' Capping Polyadenylation Intron Splicing

    Uploaded by

    Kayoung Heo
    This document summarizes pre-mRNA processing, which includes 5' capping, intron splicing, and polyadenylation. Introns are removed from pre-mRNA and exported from the nucleus as mature mRNA. These processing steps protect the mRNA from degradation and allow for translation in the cytoplasm.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 1

    Kayoung

    Heo (100125802)

    Transcription

    Pre-mRNA 5

    5 UTR

    Exon

    Intron

    Exon

    Exon

    Intron

    3 UTR

    Pre-mRNA processing

    Intron splicing

    5 Capping

    Polyadenylation

    Pre-mRNA

    Happens during transcription


    Addition of 5 7-methyl guanosine
    cap

    Introns

    Exons

    Not expressed

    Expressed

    Removed by spliceosome
    (snRNP + pre-mRNA +
    other proteins)

    Recognized by
    translation initiation
    factors

    Poly-A polymerase adds Adenine


    ~ 200 bases long

    Makes up coding
    sequence

    Allow for alternative splicing

    Protection from degradation

    No poly-A
    recognition sites
    in ribonucleases

    Protection from degradation

    Increases mRNA stability


    After processing, mRNA exits nucleus with help of carrier
    molecules

    mRNA 5

    5 CAP 5 UTR

    Exon

    Exon

    Translation

    Exon

    Regulate
    transport to
    cytoplasm

    3 UTR

    Poly-A tail

    You might also like