Calcium Gluconate Drug Study

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Name Of Drug

Dose, Route,
Freque
ncy

Generic Name:
Calcium
Gluconate

Dose:
1ampule

Brand Name:
Calgonate
Classification:
Electrolyte and
Water Balance

Route:
IV
Frequency:
Over 20
minutes.

Mechanism of
Action

Indication

Contraindication

Adverse Reaction

Nursing Responsibility

Calcium
Gluconate acts
like digitalis on
the heart,
increasing cardiac
muscle tone and
force of systolic
contractions
(positive
inotropic effect)

Negative calcium balance (As in


neonatal tetany,
hypoparathyroidism, vitamin D
deficiency, alkalosis). Also to
overcome cardiac toxicity of
hyperkalemia, for
cardiopulmonary resuscitation, to
prevent hypocalcemia during
transfusion of citrated blood. Also
as antidote for magnesium sulfate,
for acute symptoms of lead colic,
to decrease capillary permeability
in sensitivity reactions, and to
relieve muscle cramps from insect
bites or stings. Oral calcium may
be used to maintain normal
calcium balance during pregnancy,
lactation, and childhood growth
and to prevent primary
osteoporosis. Also an osteoporosis,
osteomalacia, chronic
hypoparathyroidism, rickets, and
as adjunct in treatment of
myasthenia gravis and EatonLambert syndrome.

Ventricular
fibrillation,
metastatic bone
disease, injection
into myocardium;
renal calculi,
hypercalcemia,
predisposition to
hypercalcemia
(hyperparathyroidis
m, certain
malignancies);
digitalis toxicity.

Body as a Whole:
tingling sensation.
With rapid IV,
sensations of heat
waves (peripheral
vasodilation),
fainting.
GI: PO
preparation:
constipation,
increased gastric
acid secretion.
CV: (with rapid
infusion)
hypotension,
bradycardia,
cardiac
arrhythmias,
cardiac arrest.
Skin: pain and
burning at IV site,
severe Vegas
thrombosis,
necrosis and
sloughing (with
extravasation).

Rapidly and
effectively
restores serum
calcium levels in
acute
hypocalcemia of
various origins;
also effective as a
cardiac stabilizer
under conditions
of hyperkalemia
or resuscitation.

Assess for
cutaneous burning
sensations and
peripheral vasodilation,
with moderate fall in
BP, during direct IV
injection.
Monitor ECG

during IV
administration to detect
evidence of
hypercalcemia:
decreased QT interval
associated with
inverted T-wave.
Lab tests:

determine levels of
calcium and
phosphorus and
magnesium frequently,
during sustained
therapy. Deficiencies
and other ions,
particularly
magnesium, frequently
coexist with calcium
ion depletion

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