0514 Acute Otitis Media

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A
PAGE 2| Introduction To The
Guidelines: Acute Otitis
Media

PAGE 3| Assessment Of The


Guideline Methodology
Selected Guideline
PAGE 4| Recommendations,
With Discussion
PAGE 8| References
PAGE 9| CME Questions
Editors Note: To read more about this publication
and the background and methodologies for practice
guideline development, go to:
http://www.ebmedicine.net/introduction

Updated Guidelines For The


Diagnosis And Management Of
Acute Otitis Media

his issue of EM Practice Guidelines Update reviews the


2013 update of the guideline on the diagnosis and management of acute otitis media (AOM) for healthy children aged
6 months to 12 years. Published by the American Academy of
Pediatrics (AAP) and the American Academy of Family Physicians
(AAFP), the guideline authors emphasize the use of a specific,
stringent definition of AOM to limit unnecessary treatment with antibiotics in patients without a certain diagnosis. The management
recommendations outline which children should be treated with
antibiotics immediately and which children can be offered a watch
and wait approach. This review focuses on the recommendations
most relevant to pediatric emergency medicine practice.
Practice Guideline Impact
Emergency clinicians should make the diagnosis of AOM in
children who present with: (1) moderate to severe bulging of
the tympanic membrane (TM) or new-onset otorrhea not due
to acute otitis externa; or (2) mild bulging of the TM and recent (< 48 h) onset of ear pain or intense erythema of the TM.
The management of AOM should include assessment and
treatment of pain.
Emergency clinicians should prescribe immediate antibiotic
treatment for AOM for children with otorrhea, children with
severe symptoms, and children aged 6 months to 2 years
with bilateral AOM.
Emergency clinicians can either start immediate antibiotic
treatment or offer observation (if there is good follow-up) for
children aged 6 to 23 months with nonsevere unilateral AOM
and children aged 24 months with nonsevere unilateral or
bilateral AOM.

May/June 2014
Volume 6, Number 3
Author
Kimberly Kahne, MD

Pediatric Emergency Medicine Fellow, Department of Emergency Medicine,


Icahn School of Medicine at Mount Sinai, New York, NY

Editor-In-Chief
Sigrid Hahn, MD, MPH

Assistant Professor of Emergency Medicine, Department of Emergency


Medicine, Icahn School of Medicine at Mount Sinai, New York, NY

Editorial Board
Luke K. Hermann, MD

Associate Professor of Emergency Medicine, Director of Quality and Finance,


Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai,
New York, NY

Andy Jagoda, MD, FACEP

Professor and Chair, Department of Emergency Medicine, Icahn School of


Medicine at Mount Sinai, New York, NY

Eddy S. Lang, MDCM, CCFP (EM), CSPQ

Senior Researcher, Alberta Health Services; Associate Professor, University of


Calgary; Adjunct Professor, McGill University, Montreal, Quebec, Canada

Trevor Lewis, MD, FACEP

Medical Director, Emergency Department, Cook County Hospital; Associate


Professor of Emergency Medicine, Rush Medical College, Chicago, IL

Gregory M. Press, MD, RDMS

Emergency Ultrasound Director, Hutt Valley Hospital, Lower Hutt, New Zealand

Christopher Tainter, MD, RDMS

Critical Care Fellow, Department of Anesthesia, Critical Care, and Pain


Medicine, Massachusetts General Hospital/Harvard Medical School, Boston,
MA

Scott M. Silvers, MD

Chair, Department of Emergency Medicine, Mayo Clinic, Jacksonville, FL

Scott D. Weingart, MD, FCCM

Associate Professor, Department of Emergency Medicine, Director, Division of


ED Critical Care, Icahn School of Medicine at Mount Sinai, New York, NY

Prior to beginning this activity, see CME Information


on page 9.

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Updated Guidelines For Diagnosis And Management Of Acute Otitis Media

Introduction To The Guidelines: Acute Otitis Media

The recommendations in the 2004 guideline to observe rather than


to treat with antibiotics were based on studies that used nonspecific
inclusion criteria that did not represent a patient population with highly
certain AOM. Furthermore, older studies tended to exclude very young
children with severe disease and those with recent antibiotic treatment
or recent diagnosis of AOM. Thus, the studies were not reflective of
the full spectrum of patients covered by these guidelines.8 The 2013
update relied upon studies with stringent diagnostic criteria to ensure
that the patients, indeed, had AOM, and, based on these stronger
data, actually expand the recommendations for which patients can be
observed without antibiotic treatment.

his issue of EM Practice Guidelines Update reviews the guideline


entitled The Diagnosis and Management of Acute Otitis Media,
published in Pediatrics in March 2013, available at:
http://pediatrics.aappublications.org/content/131/3/e964.long
AOM remains the leading condition for which antibiotics are prescribed
for children in the United States.1,2 It accounts for 13% of all emergency department (ED) visits and 30 million clinic visits by children,
making it the second most common diagnosis in the pediatric ED after
upper respiratory infections.3 In May 2004, the AAP and AAFP published the Clinical Practice Guideline: Diagnosis and Management of
Acute Otitis Media.4 This earlier guideline used a less-stringent definition of AOM that could have led to the misdiagnosis of children having
otitis media with effusion (OME) as having AOM. The 2004 guideline
also provided management recommendations for children with an
uncertain" diagnosis. The updated guidelines removed this category,
emphasizing the importance of good visualization of the TM and excellent otoscopic skills for accurate diagnosis to guide management.

The guideline authors acknowledge that the adherence to the 2004


guidelines was quite poor, and they comment that this, unfortunately,
parallels the impact of practice guidelines across specialties. They
highlight the need for increased dissemination of guideline content.
-- Kimberly Kahne, MD

The 2004 guideline was notable for recommending observation without


the use of antibiotics in select patients. Despite awareness and significant publicity of these 2004 recommendations, evidence has shown
that clinicians are hesitant to change their practice.5 Management of
AOM with watchful waiting rather than prescription of antibiotics did
not increase after the 2004 guideline publication.6 A 2007 study reported that up to 91% of ED patients received an antibiotic prescription
for AOM.7

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Updated Guidelines For Diagnosis And Management Of Acute Otitis Media

Assessment Of The Guideline Methodology

o create this guideline, the AAP and AAFP partnered with the
Agency for Healthcare Research and Quality and the Southern
California Evidence-Based Practice Center. Using an evidence
report created by these agencies, a multidisciplinary writing committee used BRIDGE-Wiz (Building Recommendations in a Developers
Guideline Editor) software to aid in crafting action-oriented recommendations and in determining the strength of the evidence. The relationship between the strength of the evidence and the recommendation is
shown in Table 1.

Table 1. Definition Of Evidence Quality Used In American Academy of


Pediatrics Recommendations

The author of this issue of EM Practice Guidelines Update, Kimberly


Kahne, MD, as well as the Editor-in-Chief, Sigrid Hahn, MD, MPH,
graded these guidelines using the Appraisal of Guidelines for Research and Education (AGREE) II instrument (available at
http://www.agreetrust.org/). This instrument is a checklist that allows
users to grade a guideline on 23 items in 6 domains, reflecting the
degree to which the guideline developers used unbiased, best-practice
methodology in developing the guideline and writing the recommendations. The results of the AGREE assessment are presented in Figure
1, with a percentile calculated for each domain (maximumof 100%).
The score for relevance to emergency medicine is not part of the
AGREE instrument, but reflects the judgment of the author and editor
of this issue.

Figure 1. AGREE Criteria For Acute Otitis Media Guidelines

Kimberly Kahne, MD; and Sigrid Hahn, MD, MPH

Abbreviation: AGREE, Appraisal of Guidelines for Research and Education.

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Updated Guidelines For Diagnosis And Management Of Acute Otitis Media

Selected Guideline Recommendations, With Discussion

he recommendations excerpted here are presented as they


appear in the original guidelines, including the strength of recommendation and the level of evidence. This review does not
include all recommendations provided in the original documents published by the AAP and the AAFP. Instead, it includes those recommendations most pertinent to emergency clinicians.

The guideline recommends the tools to help develop the appropriate


skills, including the following video:
http://www2.aap.org/sections/infectdis/video.cfm
These revised criteria were developed in reaction to criticisms of the
2004 definition, which lacked precision, and the fact that the guidelines
had a category of recommendations for patients with an uncertain
diagnosis, which many felt tacitly endorsed incomplete visualization
of the TM and poor otoscopic skills. The 2013 criteria were chosen to
achieve higher specificity while recognizing that the decreased sensitivity may exclude less severe presentations of AOM.

Diagnosis Of Acute Otitis Media


Key Action Statement 1A: Clinicians should diagnose AOM in
children who present with moderate to severe bulging of the TM
or new onset of otorrhea not due to acute otitis externa. (Evidence
Quality: Grade B. Strength: Recommendation)
Key Action Statement 1B: Clinicians should diagnose AOM in
children who present with mild bulging of the TM and recent (< 48
hours) onset of ear pain (holding, tugging, rubbing of the ear in a
nonverbal child) or intense erythema of the TM. (Evidence Quality:
Grade C, Strength: Recommendation)
Key Action Statement 1C: Clinicians should not diagnose AOM
in children who do not have middle ear effusion (based on pneumatic otoscopy and/or tympanometry). (Evidence Quality: Grade B,
Strength: Recommendation)

Pain Management For Acute Otitis Media


Key Action Statement 2: The management of AOM should include an assessment of pain. If pain is present, the clinician should
recommend treatment to reduce pain. (Evidence Quality: Grade B,
Strength: Strong Recommendation)
Editorial Comment: Kimberly Kahne, MD
Although many episodes of AOM are associated with pain,9 clinicians
often view it as a secondary complaint that may not require direct attention.10 Pain associated with AOM can be substantial and can last
longer in young children.11 Acetaminophen and ibuprofen are considered the mainstay of pain management for AOM.

Editorial Comment: Kimberly Kahne, MD


The challenging feature of these diagnostic criteria for many clinicians will be that they rely upon pneumatic otoscopy, and the guideline
authors call this the standard" tool for diagnosis. Although they acknowledge that many clinicians lack experience in removing cerumen
adequately or performing pneumatic otoscopy, an incomplete examination is no longer considered acceptable.

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Updated Guidelines For Diagnosis And Management Of Acute Otitis Media

Antibiotic Treatment Or Observation For Management For Acute


Otitis Media
Key Action Statement 3A: Severe AOM The clinician should
prescribe antibiotic therapy for AOM (bilateral or unilateral) in children aged > 6 months with severe signs or symptoms (ie, moderate or severe otalgia or otalgia for at least 48 hours, or temperature
39C [102.2F] or higher). (Evidence Quality: Grade B, Strength:
Strong Recommendation)
Key Action Statement 3B: Nonsevere bilateral AOM in young
children The clinician should prescribe antibiotic therapy for
bilateral AOM in children aged < 24 months without severe signs
or symptoms (ie, mild otalgia for < 48 hours, temperature < 39C
[102.2F]). (Evidence Quality: Grade B, Strength: Recommendation)
Key Action Statement 3C: Nonsevere unilateral AOM in young
children The clinician should either prescribe antibiotic therapy
or offer observation with close follow-up based on joint decisionmaking with the parent(s)/caregiver for unilateral AOM in children
aged 6 months to 23 months without severe signs or symptoms (ie,
mild otalgia for < 48 hours, temperature < 39C [102.2F]). When
observation is used, a mechanism must be in place to ensure
follow-up and begin antibiotic therapy if the child worsens or fails
to improve within 48 to 72 hours of onset of symptoms. (Evidence
Quality: Grade B, Strength: Recommendation)
Key Action Statement 3D: Nonsevere AOM in older children
The clinician should either prescribe antibiotic therapy or offer observation with close follow-up based on joint decision-making with
the parent(s)/caregiver for AOM (bilateral or unilateral) in children
aged 24 months without severe signs or symptoms (ie, mild otalgia for < 48 hours, temperature < 39C [102.2F]). When observation is used, a mechanism must be in place to ensure follow-up
and begin antibiotic therapy if the child worsens or fails to improve
within 48 to 72 hours of onset of symptoms. (Evidence Quality:
Grade B, Strength: Recommendation)

EM Practice Guidelines Update 2014

Editorial Comment: Kimberly Kahne, MD


Since the 2004 guideline, substantial research has been published on
the initial management of AOM, including randomized controlled trials
on antibiotic therapy versus placebo or no therapy.12-14 The evidencebased recommendations are summarized in Table 2.
Table 2. Recommendations For Initial Management For
Uncomplicated Acute Otitis Media
Unilateral AOM*
without otorrhea

Age

Otorrhea with
AOM*

Unilateral or
Bilateral AOM*
bilateral AOM* without otorwith severe
rhea

symptoms

6 mo 2y

Antibiotic
therapy

Antibiotic
therapy

Antibiotic therapy Antibiotic therapy


or additional
observation

2y

Antibiotic
therapy

Antibiotic
therapy

Antibiotic therapy or additional


observation

Antibiotic therapy
or additional
observation

*Applies only to children with well-documented AOM with high certainty of diagnosis.

A toxic-appearing child, persistent otalgia more than 48 h, temperature 39C (102.2F) in the

past 48 h, or if there is uncertain access to follow-up after the visit.

This plan of initial management provides an opportunity for shared decision-making with the

childs family for those categories appropriate for additional observation. If observation is offered,
a mechanism must be in place to ensure follow-up and the initiation of antibiotics if the child worsens or fails to improve within 48 to 72 h of AOM onset.
Abbreviation: AOM, acute otitis media.
Reproduced with permission from Pediatrics, Vol. 131, page e976, Copyright 2013 by the AAP.

These recommendations contrast with the 2004 guideline, which recommended antibiotic therapy for all children aged 6 months to 2 years
with a certain" diagnosis. Evidence has supported the safety of observation or delayed antibiotic usage in young children and is an appropriate management option when there is shared decision-making with the
parent.

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Updated Guidelines For Diagnosis And Management Of Acute Otitis Media

Editorial Comment: Kimberly Kahne, MD


Once the decision has been made to start antibiotics, the emergency
clinician must choose an antibiotic that will have a high likelihood of
being effective against the most likely bacterial pathogen, taking into
account cost, taste, convenience, and adverse effects.

Choice Of Antibiotics For Acute Otitis Media


Key Action Statement 4A: Clinicians should prescribe amoxicillin
for AOM when a decision to treat with antibiotics has been made
and the child has not received amoxicillin in the past 30 days or the
child does not have concurrent purulent conjunctivitis or the child
is not allergic to penicillin. (Evidence Quality: Grade B. Strength:
Recommendation)
Key Action Statement 4B: Clinicians should prescribe an antibiotic with additional beta-lactamase coverage for AOM when a
decision to treat with antibiotics has been made, and the child has
received amoxicillin in the last 30 days or has concurrent purulent
conjunctivitis, or has a history of recurrent AOM unresponsive to
amoxicillin. (Evidence Quality: Grade C. Strength: Recommendation)
Key Action Statement 4C: Clinicians should reassess the patient
if the caregiver reports that the childs symptoms have worsened
or failed to respond to the initial antibiotic treatment within 48 to
72 hours and determine whether a change in therapy is needed.
(Evidence Quality: Grade B. Strength: Recommendation)

There have been no changes to the recommendation for first-line antibiotic choice since the 2004 guideline, despite new data on the effects
of 7-valent pneumococcal conjugate vaccine (PCV7, Prevnar) and
the awareness of an increase in multidrug-resistant strains of pneumococci. High-dose amoxicillin (80-90 mg/kg per day in 2 divided doses)
yields middle ear fluid levels that exceed the minimum inhibitory
concentrations of all intermediate (and many highly resistant) strains of
Streptococcus pneumoniae. The 3 most common bacterial pathogens
in AOM remain S pneumoniae, nontypeable Haemophilus influenzae, and Moraxella catarrhalis. Since the introduction of PCV7, there
has been a shift towards H influenzae and non-PCV7 serotypes of S
pneumoniae. The antibiotic susceptibility pattern for S pneumoniae is
expected to continue to evolve with the use of 7-valent pneumococcal
conjugate vaccine (PCV13, Prevnar 13).
Tables 3 and 4 (page 7) show a number of medications that are clinically effective; however, amoxicillin remains first-line due to its effectiveness in combination with low cost, safety, acceptable taste, and
narrow microbiologic spectrum. Patients who have taken amoxicillin in
the previous 30 days, patients with concurrent conjunctivitis, or patients for whom coverage for beta-lactamase-positive H influenza and
M catarrhalis is desired should be started on amoxicillin-clavulanate
(Augmentin) at a dose of 90 mg/kg/day of amoxicillin with 6.4 mg/kg/
day of clavulanate. Alternative antibiotics vary in their efficacy against
AOM pathogens.
For children aged < 2 years and children with severe symptoms, a
standard 10-day course is recommended. A 7-day course may be recommended for children aged 2 through 5 years with mild or moderate
AOM. For children aged 6 years with mild to moderate symptoms, a
5- to 7-day course is adequate.

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Updated Guidelines For Diagnosis And Management Of Acute Otitis Media

Table 3. Recommended Antibiotics For (Initial Or Delayed) Treatment


Of Pediatric Acute Otitis Media
Recommended First-line
Treatment
Amoxicillin (80-90 mg/kg/day
in 2 divided doses)
or
Amoxicillin-clavulanate* (90
mg/kg/day of amoxicillin, with
6.4 mg/kg/day of clavulanate
[amoxicillin-to-clavulanate ratio, 14:1] in 2 divided doses)

Table 4. Recommended Antibiotics After 48-72 Hours Of Failure Of


Initial Antibiotic Treatment For Pediatric Acute Otitis Media

Alternative Treatment
(If Penicillin Allergy)



Recommended First-line
Treatment
Amoxicillin-clavulanate* (90
mg/kg/day of amoxicillin with
6.4 mg/kg/day of clavulanate
in 2 divided doses)
or
Ceftriaxone (50 mg IM or IV
for 3 days)

Cefdinir (14 mg/kg/day in 1


or 2 doses)
Cefuroxime (30 mg/kg/day in
2 divided doses)
Cefpodoxime (10 mg/kg/day
in 2 divided doses)
Ceftriaxone (50 mg IM or IV
per day for 1 or 3 days)

*May be considered in patients who have received amoxicillin in the previous 30 days or who
have the otitis-conjunctivitis syndrome.

Cefdinir, cefuroxime (Ceftin, Zinacef), cefpodoxime, and ceftriaxone (Rocephin) are highly

Alternative Treatment

Ceftriaxone, 3 days
Clindamycin (Cleocin),
30-40 mg/kg/day in 3 divided
doses, with or without a thirdgeneration cephalosporin

Failure of second antibiotic


Clindamycin (30-40
mg/kg/day in 3 divided doses)
plus third-generation cephalosporin
Tympanocentesis
Consult specialist

unlikely to be associated with cross-reactivity with penicillin allergy, on the basis of their distinct
chemical structures.

*May be considered in patients who have received amoxicillin in the previous 30 days or who

Abbreviations: IM, intramuscular; IV, intravenous

have the otitis-conjunctivitis syndrome.

Reproduced with permission from Pediatrics, Vol. 131, page e983, Copyright 2013 by the AAP.

Perform tympanocentesis/drainage if skilled in the procedure, or seek a consultation from an

otolaryngologist for tympanocentesis/drainage. If the tympanocentesis reveals


multidrug-resistant bacteria, seek an infectious disease specialist consultation.

Cefdinir, cefuroxime, cefpodoxime, and ceftriaxone are highly unlikely to be associated with

cross-reactivity with penicillin allergy on the basis of their distinct chemical structures.
Abbreviations: IM, intramuscular; IV, intravenous
Reproduced with permission from Pediatrics, Vol. 131, page e983, Copyright 2013 by the AAP.

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References
1. Grijalva CG, Nuorti JP, Griffin MR. Antibiotic prescription rates for
acute respiratory tract infections in US ambulatory settings. JAMA.
2009;302(7):758-766. (Survey)

10. Schecter NL. Management of pain associated with acute medical illness. In: Schechter NL, Berde CB, Yaster M, eds. Pain in Infants, Children, and Adolescents. Baltimore: Williams & Wilkins; 1993:537-538.
(Textbook chapter)

2. McCaig LF, Besser RE, Hughes JM. Trends in antimicrobial prescribing rates for children and adolescent. JAMA. 2002;287(23):30963102. (Survey)

11. Rovers MM, Glasziou P, Appelman CL, et al. Predictors of pain and/
or fever at 3 to 7 days for children with acute otitis media not treated
initially with antibiotics: a meta-analysis of individual patient data. Pediatrics. 2007;119(3):579-585. (Meta-analysis; 824 patients)

3. Pitts SR, Niska RW, Xu J, et al. National hospital ambulatory medical


care survey: 2006 emergency department summary. Natl Health Stat
Report. 2008;7:1-38. (Survey)

12. Hoberman A, Paradise JL, Rockette HE, et al. Treatment of acute


otitis media in children under 2 years of age. N Engl J Med.
2011;364(2):105-115. (Randomized trial; 291 patients)

4. American Academy of Pediatrics Subcommittee on Management of


Acute Otitis Media. Diagnosis and management of acute otitis media.
Pediatrics. 2004;113(5):1451-1465. (Clinical practice guidelines)

13. Thtinen PA, Laine MK, Huovinen P, et al. A placebo-controlled


trial of antimicrobial treatment for acute otitis media. N Engl J Med.
2011;364(2):116-126. (Randomized double-blind trial; 319 patients)

5. Vernacchio L, Vezina RM, Mitchell AA. Management of acute otitis


media by primary care physicians: trends since the release of the
2004 American Academy of Pediatrics/American Academy of Family
Physicians clinical practice guideline. Pediatrics. 2007;120(2):281287. (Survey)

14. Le Saux N, Gaboury I, Baird M, et al. A randomized, double-blind,


placebo-controlled noninferiority trial of amoxicillin for clinically diagnosed acute otitis media in children 6 months to 5 years of age.
CMAJ. 2005;172(3):335-341. (Randomized double-blind placebocontrolled noninferiority trial; 512 patients)

6. Coco A, Vernacchio L, Horst M, et al. Management of acute otitis


media after publication of the 2004 AAP and AAFP clinical practice
guideline. Pediatrics. 2010;125(2):214-220. (Survey)
7. Fischer T, Singer AJ, et al. National trends in emergency department
antibiotic prescribing for children with acute otitis media, 1996-2005.
Acad Emerg Med. 2007;14(12):1172-1175. (Retrospective database
study)
8. American Academy of Pediatrics Steering Committee on Quality Improvement and Management. Classifying recommendations for clinical
practice guidelines. Pediatrics. 2004;114(3)874-877. (Statement)
9. Hayden GF, Schwartz RH. Characteristics of earache among children
with acute otitis media. Am J Dis Child. 1985;139(7):721-723. (Prospective; 335 cases)

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CME Questions
To take the CME test, visit: www.ebmedicine.net/G0514 or scan the QR code below with a smartphone:

1. Which of the following patients meets criteria for the diagnosis of AOM?
a. A 3-year-old girl with otorrhea and evidence of acute otitis externa on examination
b. A 3-year-old girl with mild bulging of the TM and complaints of ear pain for the past 24 hours
c. A 3-year-old girl with moderate erythema of the TM and complaints of ear pain for the past 24 hours
d. A 3-year-old girl with upper respiratory infection symptoms and complaints of right-sided otalgia
2. Which of the following patients meets criteria for the diagnosis of AOM?
a. A 6-month-old boy with mild bulging of the TM and ear-pulling for 2 weeks
b. A 6-month-old boy with mild bulging of the TM
c. A 6-year-old boy with severe bulging of the TM
d. None of the above
3. Which antibiotic should be initiated in a 15-month-old girl diagnosed with uncomplicated bilateral AOM?
a. Amoxicillin 45 mg/kg/day divided into 2 doses
b. Amoxicillin 80-90 mg/kg/day divided into 2 doses
c. Ceftriaxone 50 mg/kg intramuscular injection x 1
d. Clindamycin 30-40 mg/kg/day in divided into 3 doses
4. In which patient is observation an inappropriate form of management?
a. A 3-year-old with unilateral AOM and severe otalgia for 48 hours
b. A 10-month-old with unilateral AOM and fever to 38.5C for 48 hours
c. A 10-month-old with bilateral AOM and fever to 38.5C for 48 hours
d. A and B
e. A and C

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To contact the Editor-In-Chief, email Sigrid Hahn, MD, MPH at:


[email protected]

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Low-Risk Chest Pain In The ED: Current Guidelines

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Neck Trauma: Current Guidelines For Emergency Clinicians

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Unstable Angina And Non-ST-Elevation Myocardial Infarction In The ED: Current Guidelines

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Current Guidelines On Atrial Fibrillation In The ED

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Current Guidelines For Management of Acute Altitude Illness, Frostbite, And Snake Envenomation (Trauma CME)

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American Heart Association Guidelines For The Emergency Clinician: Cardiac Arrest In
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Percutaneous Coronary Intervention: Current Guidelines For The ED

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Current Guidelines For Evaluating And Managing Symptomatic Early Pregnancy In The ED

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Current Guideline For The Neurodiagnostic Evaluation Of The Child With A Simple Febrile
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Current Guidelines For The Evaluation And Management Of Community-Acquired Pneumonia In The ED

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Guidelines For The Evaluation And Management Of Upper Gastrointestinal Bleeding

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Guidelines For The Evaluation And Management Of Acute Cerebrovascular Syndrome Part
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Guidelines For The Management Of Pediatric Severe Sepsis And Septic Shock

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Updated
Guidelines
For Acute
Diagnosis
And
Management
Of AcuteGuidelines
Otitis Media
Benign
Benign
Paroxysmal
Positional
Vertigo
and
Otitis
Externa
the
Benign
Paroxysmal
Positional
Vertigo
And
Acute
Otitis
Externa
Inin
The
ED: Current
Current Guidelines
BenignParoxysmal
ParoxysmalPositional
PositionalVertigo
VertigoAnd
andAcute
AcuteOtitis
OtitisExterna
ExternaIn
inThe
the ED:

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based on strength of evidence.

Diagnosis and treatment recommendations solidly based in the current literature.
Diagnosis and treatment recommendations solidly based in the current literature.

Evidence-B
ased Appro
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ToEv
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, TN


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EM Practice
Practice Guidelines Update
Update 2014
EM
EM Practice Guidelines
Guidelines Update 2009
2009

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www.ebmedicine.net
May/June 2014
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