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    SIMPIC Final Question 2015

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    Muhammad Bilal Saifulhaq
    A man suffered from a rash for three weeks. The causative agent was Penicilliosis marnefferi, a fungus found in humans. He lost 10kg in two months and was HIV positive. The phyllum of its natural reservoir is Chordata.

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    SIMPIC Final Question 2015

    Uploaded by

    Muhammad Bilal Saifulhaq
    3K views3 pages
    A man suffered from a rash for three weeks. The causative agent was Penicilliosis marnefferi, a fungus found in humans. He lost 10kg in two months and was HIV positive. The phyllum of its natural reservoir is Chordata.

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    A man suffered from a rash for three weeks. The causative agent was Penicilliosis marnefferi, a fungus found in humans. He lost 10kg in two months and was HIV positive. The phyllum of its natural reservoir is Chordata.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    3K views3 pages

    SIMPIC Final Question 2015

    Uploaded by

    Muhammad Bilal Saifulhaq
    A man suffered from a rash for three weeks. The causative agent was Penicilliosis marnefferi, a fungus found in humans. He lost 10kg in two months and was HIV positive. The phyllum of its natural reservoir is Chordata.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
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    A 35 years old man suffered from rash for three weeks.

    What is the phyllum of natural reservoir if


    this causative agent?
    Additional informations:
    Diffusely umbilicated papular rash over several areas of the body.
    Microscopic examination shows septate yeast.
    He has lost weight up to 10 kg in 2 months.
    Serology anti HIV positive.
    CD4 140 cells/mm3.
    Answers:
    Name of causative agent: Penicilliosis marnefferi
    Phyllum: Chordata
    --A 39 years old man suffered from fever and dyspnea for 1 week. What virulence factor of this
    causative pathogen plays an important role in immune evasion?
    Additional informations:
    Blood culture: found Gram positive cocci in clusters (2 samples)
    Answers:
    Name of causative agent: Staphylococcus aureus
    Diagnosis: Acute endokarditis
    Immune evasion strategy: Protein A
    --10 years old boy suffered from diarrhea for 3 days. What is the first line drug to treat the patient?
    Additional informations:
    Stool test: face like organisms with 2 nuclei
    Answers:
    Giardia lamblia
    Metronidazole
    --A 25 years old woman suffered from high grade fever for 1 day. What is major mechanism that the
    causative pathogen used to evade immune response?
    Additional informations:
    Blood test: WBC 20000 cells/mm3, 90% neutrophil
    Biochemical tests: Gram negative bacilli, lactose fermenting, negative oxidase test, positive Voges
    Proskauer test, non-motile
    Answers:
    Name of causative agent: Klebsiella pneumoniae or Klebsiella oxytoca
    Diagnosis: Klebsiella sepsis
    Immune evasion strategy: antiphagocytic trait
    --A 3 years old newborn boy had jaundice since birth. What is the estimated duration of infection
    caused by causative pathogen?

    Additional informations:
    HBsAg negative
    Anti-CMV IgM positive
    The baby was born as fullterm
    History of seizure 2 days ago
    CT scan result: brain intracranial calcification
    Answers:
    Name of causative agent: CMV
    Diagnosis: congenital CMV infection
    Duration of infection: lifelong
    --A 45 years old man suffered from... ...
    What is the natural reservoir of causative pathogen?
    Additional information:
    Bronchial wash culture showe no growth in CGB (canavanine glycine bromothymol blue) agar
    History as heavy smoker
    History of fully treated pulmonary TB 10 years ago
    Recent sputum acid fast stain showed no acid fast bacteria
    India ink preparation showed encapsulated yeast
    Answers:
    Name of causative agent: Cryptococcus neoformans
    Natural reservoir: soil contaminated by pigeon dropping
    --A 40 years old man suffered from progressive memory loss for 2 months. What is the natural
    reservoir of the causative pathogen?
    Additional informations:
    Negative Mycobacterial culture
    He has pigeon at home
    Diagnosed with Kaposi sarcoma
    Gram stain of LCS showes no bacteria
    Answers:
    Name of causative agent: HIV
    Diagnosis: HIV dementia
    Reservoir: human
    --A 35 years old man suffered from fever and headache for 3 days. What is the serotype that is most
    virulent?
    Additional informations:
    Negative Ag of Streptococcus pneumoniae
    Negative Ag of Haemophilus influenzae
    Blood test showed Gram positive cocci, alpha hemolyticus, with negative PYR test and negative
    bile esculin test
    Gram stain of blood showed Gram negative cocci in short chains
    He works as a butcher

    He also suffered from sensorineural hearing loss and neck stiffness


    Answers:
    Name of causative agent: Streptococcus suis
    The most virulent strain: serotype 2
    --A patients suffered from fever for 5 days. What is the organ that this causative agent resides?
    Additional informations:
    Sufferrd from diarrhea for 10 days
    Gram stain of the stool showed Gram negative bacilli, with negative oxidase test and positive
    citrate test
    Positive HAV IgA
    Answers:
    Name of causative agent: Salmonella enterica
    Diagnosis: typhoid fever
    Residing organ: gall bladder
    --A 30 years old man presented with rash for 1 week. What is the specific pathology of bone disease
    caused by this causative pathogen?
    Additional informations:
    Blood test showed no growth
    Positive anti measles IgG?
    Positive FTA-ABS test
    History of unsafe sex
    Also presents with painless ulcer on genetalia since 1 month ago
    Physical examination showes maculopapular rash on both palms
    Answers:
    Name of causative agent: Treponema pallidum
    Diagnosis: secondary syphillis
    Name of pathology: gumma

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