Scribd Logo
Upload

Welcome to Scribd!

  • 845 views

    Typhoid Fever Facts

    Uploaded by

    FactPalooza
    Random and neat facts about Typhoid Fever. That can also be found on http://www.FactPalooza.Com Along with many other cool and interesting random facts.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd

    Typhoid Fever Facts

    Uploaded by

    FactPalooza
    845 views2 pages
    Random and neat facts about Typhoid Fever. That can also be found on http://www.FactPalooza.Com Along with many other cool and interesting random facts.

    Copyright

    © Attribution Non-Commercial (BY-NC)

    Available Formats

    DOCX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Random and neat facts about Typhoid Fever. That can also be found on http://www.FactPalooza.Com Along with many other cool and interesting random facts.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    845 views2 pages

    Typhoid Fever Facts

    Uploaded by

    FactPalooza
    Random and neat facts about Typhoid Fever. That can also be found on http://www.FactPalooza.Com Along with many other cool and interesting random facts.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 2

    Typhoid fever

    • It is also known as Salmonella typhi or commonly


    just typhoid, is a common worldwide illness, transmitted by the
    ingestion of food or water contaminated with the feces of an
    infected person.
    • Around 430–424 BC, a devastating plague, which some
    believe to have been typhoid fever, killed one third of the
    population of Athens, including their leader Pericles.
    • The bacteria then perforate through the intestinal wall and
    are phagocytosed by macrophages.
    • The classic Widal test is negative in the first week.
    • In the second week of the infection, the patient lies
    prostrate with high fever in plateau around 40 °C (104 °F)
    and bradycardia (sphygmothermic dissociation), classically with
    a dicrotic pulse wave.
    • Delirium is frequent, frequently calm, but sometimes
    agitated.
    • The abdomen is distended and painful in the right lower
    quadrant where borborygmi can be heard.
    • Diarrhea can occur in this stage: six to eight stools in a
    day, green with a characteristic smell, comparable to pea soup.
    However, constipation is also frequent.
    • The spleen and liver are enlarged (hepatosplenomegaly) and
    tender, and there is elevation of liver transaminases.
    • The Widal reaction is strongly positive with anti O and
    anti H antibodies.
    • Blood cultures are sometimes still positive at this stage.
    (The major symptom of this fever is the fever usually rises in the
    afternoon up to the first and second week.)
    • In the third week of typhoid fever, a number of
    complications can occur intestinal hemorrhage due to bleeding in
    congested Peyer's patches; this can be very serious but is usually not
    fatal.
    • Sanitation and hygiene are the critical measures that can
    be taken to prevent typhoid.
    • Typhoid fever in most cases is not fatal.
    • It is caused by the bacterium Salmonella typhi
    • The organism is a Gram-negative short bacillus that is
    motile due to its peritrichous flagella. The bacterium grows best at
    37 °C/99 °F – human body temperature.
    • This fever received various names, such as gastric
    fever, abdominal typhus, infantile remittant fever, slow
    fever, nervous fever, pythogenic fever, etc.
    • Resistance to ampicillin, chloramphenicol, trimethoprim-
    sulfamethoxazole and streptomycin is now common, and these
    agents have not been used as first line treatment now for almost 20
    years.
    • The name of “typhoid " was given by Louis in 1829, as a
    derivative from typhus.
    • The impact of this disease falls sharply with the
    application of modern sanitation techniques.
    • Most developed countries saw declining rates of typhoid
    fever throughout the first half of the 20th century due to
    vaccinations and advances in public sanitation and hygiene.

    You might also like