Cefixime is a cephalosporin antibiotic used to treat infections. It works by inhibiting bacterial cell wall synthesis. It is 40-50% absorbed orally and distributed to bile, urine, and crosses the placenta. It is 20% excreted unchanged in urine and 60% eliminated nonrenally, some in feces. Nursing responsibilities include reviewing dosing and therapy length, instructing on administration and advising to complete the course and report side effects or worsening symptoms.
Cefixime is a cephalosporin antibiotic used to treat infections. It works by inhibiting bacterial cell wall synthesis. It is 40-50% absorbed orally and distributed to bile, urine, and crosses the placenta. It is 20% excreted unchanged in urine and 60% eliminated nonrenally, some in feces. Nursing responsibilities include reviewing dosing and therapy length, instructing on administration and advising to complete the course and report side effects or worsening symptoms.
Cefixime is a cephalosporin antibiotic used to treat infections. It works by inhibiting bacterial cell wall synthesis. It is 40-50% absorbed orally and distributed to bile, urine, and crosses the placenta. It is 20% excreted unchanged in urine and 60% eliminated nonrenally, some in feces. Nursing responsibilities include reviewing dosing and therapy length, instructing on administration and advising to complete the course and report side effects or worsening symptoms.
Cefixime is a cephalosporin antibiotic used to treat infections. It works by inhibiting bacterial cell wall synthesis. It is 40-50% absorbed orally and distributed to bile, urine, and crosses the placenta. It is 20% excreted unchanged in urine and 60% eliminated nonrenally, some in feces. Nursing responsibilities include reviewing dosing and therapy length, instructing on administration and advising to complete the course and report side effects or worsening symptoms.
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GENERIC NAME
CEFIXIME
BRAND NAME CLASSIFICATION MODE OF ACTION
Fixivin
DATE ORDERED DOSAGE INDICATION
CONTRAINDICATIONS ADVERSE EFFECTS
cephalosporin antibiotic
Cefixime binds to one or more of the penicillin-binding
proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death. Absorption: Only 40-50% is absorbed from the GI tract (oral); rate may be decreased if taken with food. Greater absorption from oral suspension than tablets. Distribution: Bile, urine (high concentrations); crosses the placenta. Protein-binding: 65%. Excretion: 20% of an oral dose excreted via urine unchanged; 60% nonrenal elimination; some is excreted via the feces from the bile. Substantially removed by dialysis. 07/26/13 (Post-operative) 100mg / 5ml; syrup, 1.5 ml BID To reduce the development of drug resistant bacteria and maintain the effectiveness of Suprax (cefixime) and other antibacterial drugs, Suprax should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria. Hypersensitivity to cephalosporin. Diarrhoea, nausea, vomiting, abdominal pain; headache, dizziness, thrombocytopenia, eosinophilia.
NURSING RESPONSIBILITIES
Review dosing schedule and prescribed length
of therapy with patient.
Instruct patient or caregiver to shake well before
measuring dose, and to measure and administer prescribed dose using dosing spoon, dosing syringe, or medicine cup.
Advise patient to take without regard to meals
but to take with food if GI upset occurs.
Instruct patient to complete entire course of
therapy even if symptoms of infection have disappeared.
Advise patient to discontinue therapy and
contact health care provider immediately if skin rash, hives, itching, or shortness of breath occur.
Advise patient to report the following signs of
superinfection to health care provider: black furry tongue, foul-smelling stools, vaginal itching or discharge, white patches in mouth.
Instruct patient to notify health care provider if
infection does not appear to improve or worsens.
Instruct patient to immediately report severe
diarrhea, diarrhea containing blood or pus, or severe abdominal cramping.