Adult Atopic Dermatitis Patients and Physical Exercise: A Swedish Questionnaire Study

Acta Derm Venereol 2014; 94: 185187
CLINICAL REPORT
Adult Atopic Dermatitis Patients and Physical Exercise: A Swedish

Questionnaire Study
Sol-Britt Lonne-Rahm1, Isabelle Sundstrm1, Klas Nordlind1 and Lars-Magnus Engstrm2
Dermatology and Venereology Unit, Department of Medicine, Solna, Karolinska University Hospital, Stockholm, and 2The Swedish School of Sport and
Health Sciences, Stockholm, Sweden
Physical activity promotes health and prevents disease.

When patients with atopic dermatitis (AD) undertake
exercise, the itch often gets worse due to sweating, and
this may reduce their engagement in physical exercise.
The aim of this study was to determine the level of physical exercise in patients with AD compared with a control group from a normal population. Our hypothesis
was that patients with AD have a lower level of physical
exercise due to their skin disease. A total of 110 patients
with AD and 196 subjects from a normal population, age
range 2034 years, answered a questionnaire. Eleven
patients with AD underwent an in-depth interview. The
patients with AD had the same level of physical exercise
and attitude to physical exercise as the normal population. Therefore, our hypothesis could not be confirmed.
In conclusion, the skin symptoms of AD do not appear to
be an obstacle to moderate physical exercise. Key words:
atopic dermatitis; adults; physical exercise; questionnaire.
with AD usually respond to sweating with generalized

itching (8). Sweating caused by exercise, fabrics, and
hot weather are the most common exacerbations in
patients with AD (9). In a study by Williams et al. (9)
sweating was the most common exacerbating item for
worsening of AD in children. In a study from Singapore
(10) the most common aggravating factors in schoolchildren were exercise, heat, and sweating.
In this study we examined whether patients with AD
engage in reduced levels of physical activity due to
their dermatitis, compared with a control group from
a normal population, by studying their exercise habits
and attitudes. The research questions, in comparing the
patient and control groups, investigated whether there
are differences in (i) exercise habits; (ii) motives for
exercise; (iii) exercise during childhood and adolescence; and (iv) satisfaction with physical performance.
Accepted Nov 6, 2012; Epub ahead of print Aug 27, 2013
MATERIALS AND METHODS
Acta Derm Venereol 2014; 94: 185187.
Patients and data collection
Sol-Britt Lonne-Rahm, Department of Dermatology, Karolinska University Hospital, Solna, SE-171 76 Stockholm,
Sweden. E-mail: [email protected]
Physical activity is a well-recognized approach to the

enhancement of general health (1). Regular physical
activity helps people to avoid weight gain and plays a
part in increasing well-being (2). Physical inactivity is
recognized as a significant, common, and preventable
risk factor for conditions such as coronary artery disease,
stroke, hypertension, and osteoporosis (3).
Atopic dermatitis (AD) is a common chronic skin
disease characterized by dry, itchy skin. AD affects
approximately 2% of the adult population worldwide
(4). The aetiology of AD is unknown, but it is probably
multifactorial, with interactions between several genetic
and environmental factors (5, 6).
A common assumption is that people with AD do
not exercise because of itching. Yet regular sports may
be of adjuvant therapeutic value in patients with AD (7).
Sweating due to cholinergic sweat gland activity predominantly serves thermoregulation, and is triggered,
among other factors, by physical stress. Individuals
2014 The Authors. doi: 10.2340/00015555-1556
Journal Compilation 2014 Acta Dermato-Venereologica. ISSN 0001-5555
The study was approved by the ethics board at Karolinska

University Hospital, regarding both the patients with AD and
the control group.
A questionnaire was sent to 271 consecutive patients in the
age range 1860 years, who had visited the Department of
Dermatology, Karolinska University Hospital, Solna during
the first half year of 2004, and who had received a diagnosis
of AD from a dermatologist who is a specialist in inflammatory
skin diseases at our department. The patients had been referred
by family doctors due to substantial problems with their AD.
The questionnaire comprised 36 questions; including subquestions (11). Five of these questions were of special interest
for the present study, and were analysed further. These included
educational level, exercise level, sports activities during childhood and adolescence, motives for exercise, and satisfaction
with their physical performance. The response rate for each
given item always reached 95%.
From the patient cohort we selected all those who were be
tween the ages of 20 and 34 years, a total of 110 individuals
(72 women and 38 men). The age range 2034 years constitutes
an active period with a minimum of co-morbidities. We then
compared these patients with a control group of 196 age- and
sex-matched subjects (114 women and 82 men).
The control group comprised participants drawn randomly
from the Swedish population and address registry, which includes all people registered as Swedish citizens. They came from
8 (out of 21) geographically defined representative regions of
Sweden. The study originally included 1,065 participants (with
79% response) (12).
Acta Derm Venereol 94
186
S.-B. Lonne-Rahm et al.
Previous studies have shown that physical activity is strongly

related to age as well as to education (13). In this respect, the patient
and control groups were quite comparable; having the same age
range (2034 years) and educational levels. Approximately onethird of both groups had university educations. The data collection
was also conducted using in-depth interviews with 11 individuals
(1 male and 10 females) with diagnoses of AD (see Appendix S11).
Statistical analysis
SPSS version 17 statistical software was used. The differences
between the groups regarding the investigated parameters were
tested using a c2 test, with the level of significance set at p<0.05.
RESULTS
After one reminder about the questionnaire the response
rate was 72%.
Physical exercise habits
Defining physical activity as engaging in more strenuous exercise at least once a week, it was found that 56%
of the female patient group reported that they were at
this level, compared with 50% of the control group.
The corresponding proportions among men were 58%
and 55%, respectively. Thus, there were no statistically
significant differences between the patient and control
groups (Table I), although there were some differences
regarding maximum effort.
The in-depth interview revealed that the patient group
exercised as much as the rest of the population. Many
patients avoided swimming and preferred to exercise
outside, where they would not become as sweaty (see
Appendix SI1).
We can therefore conclude that there were no differences between the groups, and no differences between
women and men in terms of physical activity.
Because there was only a slight difference between
the sexes, females and males are presented together in
analysing further parameters.
http://www.medicaljournals.se/acta/content/?doi=10.2340/00015555-1556
Table II. Sports activities during childhood and adolescence
Activity
Patient groupa
n=105
%
Control group
n=175
%
Active in a sports club

Active outside a sports club
Not active
Total
76
9
15
100
1
18
11
100
=4.84, df=2, p>0.05.
a 2
Motivation for exercise

Regarding motivation for exercise there were no differences between the patient and control groups. The
most important motives in both groups were: a sense
of well-being; to get fit; and the pleasure of exercising.
In the interviewed group the patients also confirmed
these motives and that sweating did not prevent them
from exercising.
Exercise during childhood and adolescence
There were no differences between patient and control
groups in terms of sports or recreational habits during
childhood and adolescence (Table II). The patients
participated in sports clubs during adolescence to the
same extent as the control group. Thus, in this respect
they appeared to have had a similar experience of physical activity during adolescence, which the interviews
also confirmed.
Satisfaction with physical performance
In a self-evaluation question about satisfaction with
their physical performance, there were no differences
between the groups. Somewhat more than half of the
respective groups were not satisfied with their physical
performance (Fig. 1).
DISCUSSION
In this study no differences were found between patients with AD and a control cohort regarding exercise
Table I. Physical exercise habits

Menb
Womena
Exercise
Patient group
n=70
%
Control group
n=114
%
Patient group
n=38
%
Control group
n=81
%
Very little
A few walks
Everyday exercise
Light physical activity at least once a week
More strenuous exercise, such as fast walking, at least once a week
Regular hard training or competition
Total
0
7
16
21
36
20
100
1
2
21
26
37
13
100
3
3
18
18
32
26
100
3
6
16
20
18
37
100
=6.30, df=5, p>0.05; b2=3.59, df=5, p>0.05.
a 2
Atopic dermatitis and exercise

60
Control group
Patients with AD
50
40
30
In conclusion, the skin symptoms of AD do not seem

to be an obstacle to moderate physical exercise. This
information will be of importance to dermatologists and
to patients of different ages with AD.
ACKNOWLEDGEMENTS
20
This study was funded by grants from the Asthma and Allergy
Foundation, the Finsen/Welander Foundation, and Karolinska
Institutet. The authors would like to thank Nurse Anna slund
for valuable assistance with the enquiries to the patients.
10
0
187
Completely
satisfied
Mostly
satisfied
Not satisfied
Not satisfied
at all
Fig. 1. Satisfaction with physical performance (%).
habits, motives for exercise, exercise during childhood

and adolescence, or satisfaction with their physical performance. This was shown in both the questionnaires
responses and the in-depth interviews.
Earlier studies (8, 9) have indicated that exercise and
sweating are significant worsening factors for AD symptoms in schoolchildren. Our study indicates that even in
that period there is no difference in sports or recreational
habits between patients with AD and controls. In our
study we have no information about the start of AD in
the patients. However, it is likely that the majority of
our adult patients had the diagnosis of AD as children.
We hypothesized that the patient population would
avoid exercise activities that lead to worsening of their
disease. Against this background the results of this study
are interesting because they show that a moderate level
of exercise is no obstacle for patients with AD.
The fact that the group of patients with AD did not
perceive their physical performance differently from the
control group also indicated that AD is not an obstacle
to an active lifestyle.
This study has some limitations. First, the climate is of
importance. The climate may have an impact on the skin
barrier and also may affect the type of exercise, in- or
outdoors. The Swedish climate is cold and dry for a substantial part of the year. Secondly, the level of exercise
activity in the Swedish population is generally rather
modest (only approximately 50% of the adult population
undertake physical exercise corresponding to at least a
brisk walk once a week), which may make it difficult
to measure any difference. Testing the patients with AD
at a higher level of indoor exercise might have given
other results, as many patients prefer to be outdoors
when engaging in sports. Another possible limitation
is that co-morbidity with asthma or hay fever was not
considered. In addition, it may have been of interest to
look at specific sport activities. However, such a study
would need a substantially increased cohort.
The authors declare no conflicts of interest.
REFERENCES
1. Haskell WL, Lee IM, Pate RR, Powell KE, Blair SN, Franklin
BA, et al. Physical activity and public health: updated recommendations for adults from the American College of Sports
Medicine and the American Heart Association. Circulation
2007; 116: 10811093.
2. Stear S. Health and fitness series 1. The importance of
physical activity for health. J Fam Health Care 2003; 13:
1013.
3. Booth FW, Lees SJ. Fundamental questions about genes,
inactivity, and chronic diseases. Physiol Genomics 2007;
28: 146157.
4. Leung DYM, Bieber T. Atopic dermatitis. Lancet 2003;
361: 151160.
5. Pastar Z, Lipozencic J, Ljubojevic S. Etiopathogenesis of
atopic dermatitis an overview. Acta Dermatovenerol Croat
2005; 13: 5462.
6. Morren MA, Przybilla B, Bamelis M, Heykants B, Reynaers
A, Degreef H. Atopic dermatitis: triggering factors. J Am
Acad Dermatol 1994; 31: 467473.
7. Salzer B, Schuch S, Rupprecht M, Hornstein OP. Group
sports as adjuvant therapy for patients with atopic eczema.
Hautarzt 1994; 45: 751755.
8. Stern UM, Salzer B, Schuch S, Hornstein OP. Sex-dependent differences in sweating of normal probands and
atopic patients in cardiovascular stress. Hautarzt 1998;
49: 209215.
9. Williams JR, Burr ML, Williams HC. Factors influencing atopic dermatitis a questionnaire survey of
schoolchildrens perceptions. Br J Dermatol 2004; 150:
11541161.
10. Tay YK, Kong KH, Khoo L, Goh CL, Giam YC. The prevalence and descriptive epidemiology of atopic dermatitis
in Singapore school children. Br J Dermatol 2002; 146:
101106.
11. Ekblom B, Engstrm LM, Ekblom O. Secular trends of
physical fitness in Swedish adults. Scand J Med Sci Sports
2007; 17: 267273.
12. Ekblom-Bak E, Hellenius ML, Ekblom O, Engstrm LM,
Ekblom B. Fitness and abdominal obesity are independently
associated with cardiovascular risk. J Int Med 2009; 266:
547557.
13. Engstrm L-M. Who is physically active? Culture capital
and sports participation from adolescence to middle age a
38-year follow-up study. Phys Educ Sports Pedagog 2008;
13: 319343.

Adult Atopic Dermatitis Patients and Physical Exercise: A Swedish Questionnaire Study

Uploaded by

Copyright:

Available Formats

Adult Atopic Dermatitis Patients and Physical Exercise: A Swedish Questionnaire Study

Uploaded by

Document Information

Original Title

Copyright

Available Formats

Share this document

Share or Embed Document

Sharing Options

Did you find this document useful?

Is this content inappropriate?

Copyright:

Available Formats

Adult Atopic Dermatitis Patients and Physical Exercise: A Swedish Questionnaire Study

Uploaded by

Copyright:

Available Formats

Acta Derm Venereol 2014; 94: 185187

Adult Atopic Dermatitis Patients and Physical Exercise: A Swedish

Physical activity promotes health and prevents disease.

with AD usually respond to sweating with generalized

Accepted Nov 6, 2012; Epub ahead of print Aug 27, 2013

MATERIALS AND METHODS

Acta Derm Venereol 2014; 94: 185187.

Patients and data collection

Physical activity is a well-recognized approach to the

The study was approved by the ethics board at Karolinska

S.-B. Lonne-Rahm et al.

Previous studies have shown that physical activity is strongly

Table II. Sports activities during childhood and adolescence

Active in a sports club

=4.84, df=2, p>0.05.

Motivation for exercise

Table I. Physical exercise habits

=6.30, df=5, p>0.05; b2=3.59, df=5, p>0.05.

Acta Derm Venereol 94

Atopic dermatitis and exercise

In conclusion, the skin symptoms of AD do not seem

Fig. 1. Satisfaction with physical performance (%).

habits, motives for exercise, exercise during childhood

The authors declare no conflicts of interest.

Acta Derm Venereol 94

You might also like