Drug Study Cytotec

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DRUG STUDY

DRUG NAME DOSAGE, ROUTE, FREQUENCY


Generic Name: Misoprostol tab Brand Name: Cytotec PO (Adults): Antiulcer200 mcg 4 times daily with or after meals and at bedtime, or 400 mcg twice daily, with the last dose at bedtime. If intolerance occurs, dosage may be decreased to 100 mcg 4 times daily. Termination of Pregnancy400 mcg single dose two days after mifepristone if abortion has not occurred. -treatment for induced gastric ulcer. Acts as a prostaglandin analogue, decreasing gastric acid secretion (antisecretory effect) and increasing the production of protective mucus (cytoprotective effect) . Causes uterine contractions. Contraindicated in: Hypersensitivity to prostaglandins; Pregnancy or lactation (when used to prevent NSAID-induced gastric injury). CNS: headache. GI: abdominal pain, diarrhea, constipation, dyspepsia, flatulence, nausea, vomiting. GU: miscarriage, menstrual disorders.

INDICATION / ACTION

CONTRAINDICA TIONS

ADVERSE EFFECTS

NURSING RESPONSIBILI TIES


-Instruct patient to take medication as directed for the full course of therapy, even if feeling better. Take missed doses as soon as possible unless almost time for next dose; do not double doses. Emphasize that sharing of this medication may be dangerous. -Inform patient that misoprostol will cause spontaneous abortion. Women of childbearing age must be informed of this effect through verbal and written information and must use contraception throughout

DRUG STUDY
therapy. If pregnancy is suspected, the woman should stop taking misoprostol and immediately notify her health care professional. -Inform patient that diarrhea may occur. Health care professional should be notified if diarrhea persists for more than 1 wk. Also advise patient to report onset of black, tarry stools or severe abdominal pain. -Advise patient to avoid alcohol and foods that may cause an increase in GI irritation.

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