Bronchial Asthma

Bronchial asthma
Alternate Names: Asthma - bronchial; Exercise induced asthma - bronchial

Causes and Risks:
Asthma is a disease in which inflammation of the airways causes airflow into and out of the lungs to
sometimes be restricted. When an asthma attack occurs, the muscles of the bronchial tree become tight
and the lining of the air passages swells, reducing airflow and producing the characteristic wheezing
sound. Mucus production is increased.
Most people with asthma have periodic wheezing attacks separated by symptom-free periods. Some
asthmatics have chronic shortness of breath with episodes of increased shortness of breath. Asthma
attacks can last minutes to days, and can become dangerous if the airflow becomes severely restricted.
In sensitive individuals, asthma symptoms can be triggered by inhaled allergens (allergy triggers) such as
pet dander, dust mites, cockroach allergens, molds, or pollens. Asthma symptoms can also be triggered by
respiratory infections, exercise, cold air, tobacco smoke and other pollutants, stress, food or drug
allergies. Aspirin and other non-steroidal anti-inflammatory medications (NSAIDS) provoke asthma in
some patients.
Bronchial asthma is found in 3-5% of adults and 7-10% of children. Half of the people with asthma
develop it before age 10 and most develop it before age 30. Asthma symptoms can decrease over time,
especially in children.
Many people with bronchial asthma have an individual and/or family history of allergies such as hay
fever (allergic rhinitis) or eczema. Others have no history of allergies or evidence of allergic problems.
Prevention:
Asthma symptoms can be substantially reduced by avoiding exposure to known allergens and respiratory
irritants. If an asthmatic is sensitive to dust mites, exposure can be reduced by encasing mattresses and
pillows in allergen-impermeable covers, removing carpets from bedrooms, and by vacuuming regularly.
Exposure to dust mites and mold can be reduced by lowering indoor humidity. If a person is allergic to an
animal that cannot be removed from the home, the animal should be kept out of the patient’s bedroom.
Filtering material can be placed over the heating outlets to trap animal dander. Exposure to cigarette
smoke, air pollution, industrial dusts, and irritating fumes should also be avoided.
Allergy desensitization may be helpful in reducing asthma symptoms and medication use, but the size of
the benefit compared to other treatments is not known.
Symptoms:
• wheezing
○ usually begins suddenly
○ is episodic
○ may be worse at night or in early morning
○ aggravated by exposure to cold air
○ aggravated by exercise
○ aggravated by heartburn (reflux)
○ resolves spontaneously
○ relieved by bronchodilators (drugs that open the airways)
• cough with or without sputum (phlegm) production
• shortness of breath that is aggravated by exercise
• breathing that requires increased work
• intercostal retractions (pulling of the skin between the ribs when breathing)
Emergency symptoms:
• extreme difficulty breathing
• bluish color to the lips and face
• severe anxiety
• rapid pulse
• sweating
• decreased level of consciousness (severe drowsiness or confusion) during an asthma attack
Additional symptoms that may be associated with this disease:
• nasal flaring
• coughing up blood
• chest pain
• breathing which temporarily stops
• tightness in the chest
• abnormal breathing pattern, in which exhalation (breathing out) takes more than twice as long as
inspiration (breathing in)
Signs and Tests:
Listening to the chest (auscultation) during an episode reveals wheezing. However, lung sounds are
usually normal between episodes.
Tests may include:
• pulmonary function tests
• chest X-ray
• allergy testing by skin testing or serum tests
• arterial blood gas
• eosinophil (a type of white blood cell) count
Treatment:
Treatment is aimed at avoiding known allergens and respiratory irritants and controlling symptoms
through medication. Allergens can sometimes be identified by noting which substances cause an allergic
reaction. Allergy testing can also be helpful in identifying allergens in patients with persistent asthma.
Common allergens include pet dander, dust mites, cockroach allergens, molds, and pollens. Common
respiratory irritants include tobacco smoke, pollution, and fumes from burning wood or gas.
A variety of medications for treatment of asthma are available. These include:

• anti-inflammatory medications
• inhaled corticosteroids (Azmacort, Vanceril, AeroBid, Flovent)
• oral or intravenous corticosteroids (such as prednisone, methylprednisolone, and hydrocortisone)
• leoukotriene inhibitors (Singulair, Accolate)
• nedocromil sodium
• bronchodilators
• short-acting (lasting a short time), inhaled or oral (Proventil, Alupent, Bronkosol, and others)
• long-acting (lasting a long time), inhaled (Serevent)
• cromolyn sodium (Intal), is used to prevent attacks, not for treatment during an attack
• aminophylline or theophylline
People with mild asthma (infrequent attacks) may use inhalers as needed. Those with significant asthma
(symptoms occurring more than twice per week) should be treated with anti-inflammatory medications,
preferably inhaled corticosteroids, and then with bronchodilators such as inhaled Alupent or Vanceril.
Acute severe asthma requires a medical evaluation and may require hospitalization, oxygen, and
intravenous medications.
A peak flow meter, a simple device to measure lung volume, can be used at home daily to check on lung
functions. This often helps determine when medication is needed or can be tapered in the case of an
exacerbation of symptoms. Peak flow values of 50-80% of an individual’s personal best indicate a
moderate asthma exacerbation, while values below 50% indicate a severe exacerbation.
Support Groups:
The stress caused by illness can often be helped by joining a support group, where members share
common experiences and problems. See asthma and allergy - support group.
Prognosis:
There is no cure for asthma, though symptoms sometimes decrease over time. With proper self
management and medical treatment, most people with asthma can lead normal lives.
Complications:
• respiratory fatigue
• pneumothorax
• death
• side effects of the medication used

Bronchial Asthma

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Bronchial asthma

Alternate Names: Asthma - bronchial; Exercise induced asthma - bronchial

A variety of medications for treatment of asthma are available. These include:

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