M Tech Biotech Curriculum

M. Tech.
(Biotechnology) Programme Code: MTB Duration 2 Years Full Time
Programme Structure And Curriculum & Scheme of Examination 2007
AMITY UNIVERSITY UTTAR PRADESH

GAUTAM BUDDHA NAGAR
PREAMBLE
Amity University aims to achieve academic excellence by providing multi-faceted education

to students and encourage them to reach the pinnacle of success. The University has designed a system that would provide rigorous academic programme with necessary skills to enable them to excel in their careers. This booklet contains the Programme Structure, the Detailed Curriculum and the Scheme of Examination. The Programme Structure includes the courses (Core & Elective), arranged semester wise. The importance of each course is defined in terms of credits attached to it. The credit units attached to each course has been further defined in terms of contact hours i.e. lecture Hours (L), Tutorial Hours (T), Practical Hours (P). Towards earning credits in terms of contact hours, 1 Lecture and 1 Tutorial per week are rated as 1 credit each and 2 Practical hours per week are rated as 1 credit. Thus, for example, an L-T-P structure of 3-0-0 will have 3 credits, 3-1-0 will have 4 credits, and 3-1-2 will have 5 credits. The Curriculum & Scheme of Examination of each course includes the course objectives, course contents, scheme of examination and the list of text & references. The scheme of examination defines the various components of evaluation and the weightage attached to each component. The different codes used for the components of evaluation and the weightage attached to them are: Components Case Discussion/ Presentation/ Analysis Home Assignment Project Seminar Viva Quiz Class Test Term Paper End Semester Examination Codes C H P S V Q CT TP EE Weightage (%) 10 - 15 5 - 10 10 - 15 5 - 10 5 - 10 5 - 10 20 10 - 15 60
It is hoped that it will help the students study in a planned and a structured manner and promote effective learning. Wishing you an intellectually stimulating stay at Amity University.
September 2007
PROGRAMME OBJECTIVE
Biotechnology is the technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use.The main objective of this programme is to provide a balanced and comprehensive knowledge of the basic as well as applied sciences related to Biotechnology that would enhance the basic aptitude of each student and prepare them to take up the challenges in the varied and multifaceted applications of Biotechnology. It will empower the students with the latest tools, techniques and awareness in biotechnology and will facilitate comprehensive learning combining the scientific and technological aspects
PROGRAMME STRUCTURE
FIRST SEMESTER
Course Code MTBBT 10101 MTBBT 10102 MTBBT 10103 MTBBT 10104 MTBPL 10121 MTBPL 10122 MTBPL 10123 MTBTP 10130 MTBBS 10101 MTBBS 10102 MTBFR 10101 MTBGR 10101 MTBSH 10101 MTBJP 10101 MTBCE 10101 Course Title Biochemistry & Metabolic Regulation Advanced Microbial Technology Instrumentation in Biotechnology Bioinformatics Biochemistry & Microbiology Lab. Instrumentation in Biotechnology Lab Bioinformatics Lab Term Paper - I Communicational Skills- I Behavioural Science- I Foreign Language - I French German Spanish Japanese Chinese TOTAL Lecture (L) Hours Per Week 4 4 4 3 1 1 2 Tutorial (T) Hours Per Week 1 1 1 Practical (P) Hours Per Week 4 2 2 Total Credits 4 4 4 4 2 2 2 3 1 1 2 Page No.
29
SECOND SEMESTER
MTBBT 10201 MTBBT 10202 MTBBT 10203 MTBBT 10204 MTBBT 10205 MTBBT 10206 MTBBT 10207 MTBBT 10208 MTBBT 10209 MTBPL 10221 MTBPL 10222 MTBTP 10230 MTBBS10201 MTBBS10202 MTBFR 10201 MTBGR 10201 MTBSH 10201 MTBJP 10201 MTBCE 10201 Cell & Molecular Biology Recombinant DNA Technology Bioprocess Technology Elective-I (any one) Artificial Neural Networks Biosensors Environmental Biotechnology Agriculture Biotechnology Fundamentals of Computers and IPR, Biosafety & Bioethics Cell, Molecular Biology & Recombinant DNA Technology Lab Bioprocess Technology Lab Term Paper - II Communicational Skills- II Behavioural Science- II Foreign Language - II French German Spanish Japanese Chinese TOTAL
Programming in C
4 4 4 4
4 4 4 4
1 1 2
1 1 -
4 4 -
3 3 3 1 1 2
29
SUMMER PROJECT: 8 - 10 WEEKS THIRD SEMESTER

MTBBT 20301 MTBBT 20302 MTBBT 20303 Immunology and Immunotechnology Enzymology and Enzyme Technology Drug Design and Development 4 4 4 4 4 4
MTBBT 20304 MTBBT 20305 MTBBT 20306 MTBBT 20307 MTBBT 20308 MTBBT 20309
Elective - II (any one) Pollution Prevention Fundamentals Drug Delivery Systems Bio-energy Engineering Advanced Food Technology Industrial Safety and Management Advanced Animal and Plant Cell Technology Immunology and Immunotechnology Lab Enzymology and Enzyme Technology Lab Term Paper - III Communicational Skills- III Behavioural Science- III Foreign Language - III French German Spanish Japanese Chinese Summer Project Evaluation TOTAL
MTBPL 20321 MTBPL 20322 MTBTP 20330 MTBBS 20301 MTBBS 20302 MTBFR 20301 MTBGR 20301 MTBSH 20301 MTBJP 20301 MTBCE 20301 MTBPR 20370
1 1 2
1 1 -
4 4 -
3 3 3 1 1 2
9 38
FOURTH SEMESTER
MTBBT 20401 MTBBT 20402 MTBBT 20403 MTBPL 20421 MTBBS 20401 MTBBS 20402 MTBFR 20401 MTBGR 20401 MTBSH 20401 MTBJP 20401 MTBCE 20401 MTBPR 20470 Genomics and Proteomics Pharmaceutical Technology Bioprocess Plant Design Genomics and Proteomics Lab Communicational Skills- IV Behavioural Science- IV Foreign Language - IV French German Spanish Japanese Chinese Project (12 - 16 weeks) TOTAL 4 4 4 1 1 2 4 4 4 4 2 1 1 2
16 34
BIOCHEMISTRY AND METABOLIC REGULATION

Course Code: Course Objective:
The objectives of the Metabolic Biochemistry course are to provide a comprehensive understanding of human metabolism in areas of enzymology and protein structure and function; energy releasing and energy consuming metabolic processes; the regulation of synthesis and breakdown of sugars, lipids, nucleic acids, and amino acids which is necessary for further work in the biochemical/biomedical and biotechnology areas.
MTBBT 10101
Credit Units: 04
Course Contents:
Module I Structure of Biomolecules, Metabolism of Carbohydrates, Lipids, Proteins, Amino acids and Nucleic acids. Module II Photosynthesis in Microorganisms; Role of chlorophylls, carotenoids and phycobilins; Calvin cycle; Chemolithotrophy; hydrogen- iron-nitrite-oxidizing bacteria; nitrate and sulfate reduction; methanogenesis and acetogenesis; Bacterial fermentations. Module III Modes of Regulation: Different levels of regulation - protein synthesis/degradation, allosteric regulation, reversible covalent modification, proteolytic processing, Requirements for ATP in synthesis and degradation cycle, Reversibility of the different methods of regulation, Consequences of misregulation Module IV Regulation of metabolic pathways: Glycolysis/glycogenolysis, Phosphogluconate/Citric Acid Cycle, Oxidative Phosphorylation, Fatty acid oxidation, Fatty Acid Biosynthesis, Amino Acid Oxidation, Regulation of Metabolism for the production of Primary and Secondary Metabolites with case studies
Examination Scheme:
Components Weight age (%) H 10 S/Q/V 10 CT 20 EE 60
Text & References:

Text: Principles of Biochemistry by A. Lehninger revised by Nelson and Cox. Biochemistry by Mathews, Van Holde and Ahern. IIIrd Edition. References: Biochemistry by White, Handler and R.B.Smith 7th Ed. 1983 Biochemistry by L.Stryer Third Edition. Biochemistry by Voet and Voet. Fundamentals of Biochemistry by Conn and Stumph.
ADVANCED MICROBIAL TECHNOLOGY

An introduction to microorganisms, their morphology, reproduction, cultivation, metabolism, genetics, ecology of microorganisms and their relationships to health and environment
MTBBT 10102
Credit Units: 04
Course Contents:
Module I Introduction (bacteria, fungi, algae, protozoa and viruses), Contribution of Scientists, Kochs Postulates, methods in Microbiology -Principles of microbial nutrition, Culture media, Theory and practice of sterilization, pure culture techniques, Enrichment culture techniques and Microbial lab techniques. Module II Prokaryotic structure and function - Microbial nutrition and growth - Arithmatic and Geomatric Growth expression, mathematical expression of growth, growth curve, measurement of growth and growth yields, synchronous growth, continuous culture, Diauxic growth, culture collection and maintenance of cultures. Module III Microbial evolution, systematics and taxonomy - new approaches to bacterial taxonomy, classification including ribotyping, characteristics of primary domains, taxonomy, nomenclature and Bergey's manual, ribosomal RNA sequencing, microbial regulation of gene expression (attenuation and negative regulation with e.g. trp and lac operon), transfer of genetic material: plasmids, transposons, transduction, transformation and conjugation . Module IV Host-parasite relationship -Normal micro flora of skin, oral cavity, gastrointestinal tract; entry of pathogens into the host, types of toxins (Exo, endo, entro) and their mode of actions, Plant -Microbe Interactions, Microbial pathogenesis -Disease reservoirs; Epidemiological terminologies; Infectious disease transmission Module V Chemotherapy/antibiotics -Antimicrobial agents, sulfa drugs, antibiotics -penicillin and cephalosporins, broad spectrum antibiotics, antibiotics from prokaryotes. antifungal antibiotics; mode of action, resistance to antibiotics
Examination Scheme:
Text & References:

Text: Microbiology VI Edition, M.J. Pelczar, E.C.S. Chan and N.R. Kreig, Tata McGraw Hill. Microbiology by Prescott. References: General Microbiology, R.Y. Stanier, J.L. Ingraham, M.L.Wheelis and P.R. Painter, Macmillian Principles of Microbiology, R.M. Atlas, Wm C. Brown Publisher. The microbes An Introduction to their Nature and Importance, P.V. Vandenmark and B.L. Batzing, Benjamin Cummings. The Microbial World, Roger Y. Stanier, Prentice Hall Microbiology, Tortora, Funke and Chase, Benzamin & Cummings
INSTRUMENTATION IN BIOTECHNOLOGY
Course Code:
Course Objective:
To demonstrate a thorough knowledge of the equipment and operating modes of instrumentation systems used in the area of biotechnology and critically discuss the limitations and biohazards of the equipment and techniques employed in biotechnology
MTBBT 10103
Credit Units: 04
Course Contents:
Module I Ultracentrifugation: Sedimentation equilibrium and sedimentation velocity methods, Analytical and Preparative centrifuges, application of density gradient and differential centrifugation. Module II Gel electrophoresis: Agarose and Polyacrylamide , Two -dimensional electrophoresis, Isoelectric focussing, Capillary electrophoresis, Pulse-field gel electrophoresis, Immunoelectrophoresis. Module III TLC gas chromatography, gel filtration, ion-exchange chromatography, affinity chromatography and HPLC, FPLC. Module IV UV and visible Spectroscopy, Spectrofluorimetry, Atomic absorption spectrophotometry, Mass Spectrometry, Infrared and Raman Spectroscopy, Mossbauer, MALDITOF, Nuclear Magnetic Resonance and Electron Spin Resonance Spectroscopy, Magnetic Resonance Imaging. X -Ray diffraction, Electron diffraction, Neutron Diffraction. Module V Optical and Electron Microscopy, Transmission and Scanning Electron Microscopy, Tunneling Electron Microscopy, Atomic Force Microscopy, Polarization and Fluorescence microscopy. Module VI Radio tracers, GM Counter, Proportional and Scintillation Counters, Autoradiography, Radio -immunoassay.
Examination Scheme:
Text & References:

Text:
Practical Biochemistry, Principles & Techniques by Keith Wilson and John Walker. Biophysical Chemistry by David Friefelder.
References:
Microscopic Techniques in Biotechnology by Michael Hoppert Principles & Practice of Bioanalysis by Richard F. Venn Advanced Instrumentation, Data Interpretation, and Control of Biotechnological Processes by J.F. 4.Van Impe, Kluwer Academic Crystal Structure Analysis by J.P. Glusker and K.N. Trueblood, Oxford University Press Crystallography made Crystal Clear by G. Rhodes, Academic Press NMR Spectroscopy: Basic Principles, Concepts and Applications in Chemistry by H. Gunter, John Wiley and Sons Ltd. 8. Principles of Physical Biochemistry by K.E. Van Holde, Prentice Hall.
BIOINFORMATICS
Course Code:
Course Objective:
The objective is to describe data models and database management systems with an emphasis on biologically important techniques to store various data on DNA sequencing structures, genetic mapping, phylogenetic analysis. Multiple sequence alignment, protein structure prediction, and comparative genome analysis.
MTBBT 10104
Credit Units: 04
Course Contents :
Module I Introduction and overview: The NCBI, sequence databases, sequence retrieval, sequence file formats, submitting DNA and protein sequences, sequence assembly. Module II Exact string matching -classical comparison based methods, semi numerical string matching, suffix trees construction and application, Databases and rapid sequence analysis Blast and Fasta , sequence comparison by statistical content; Dynamic programming alignment -The number of alignments, shortest and longest paths in a network, global distance and similarity alignments, Fitting one sequence onto the other, trace backs, parametric sequence comparison . Module III Global and local alignments, scoring matrices-pam and blosum and gap penalties, filtering, position specific scoring matrices, internet resources , uses of multiple sequence alignment programs and methods pattern searching programs, family and superfamily representation, profit analysis. Module IV Trees-representation of sequences, tree interpretation, Distance additive, ultrameric and nonadditive distances, tree building methods, phylogenetic analysis, parsimony, Bootstrap, maximum likelihood trees , estimating the rate of change, likelihood and trees; analysis software. Module V Annotation, ESTs databases, comparative genome analysis clustering, gene discovery, protein identification, physical properties, motifs and patterns, structure, folding classes, structure classification; Structure databases PDB and MMDB, visualizing structural information, Docking of Molecules, structure prediction in proteins, prediction of buried residues in proteins, RNA secondary structure minimum free-energy structures, Genome analysis, genome rearrangements with inversions, gene identification, gene expression, expression analysis, gene identification and functional classification.
Examination Scheme:
Text & References:

Text: Essentials of Genomics and Bioinformaticsby C.W. Sensen, John Wiley and Sons Bioinformatics: Sequence and Genome Analysis by D.W. Mount, Cold Spring Harbor Laboratory Press. Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins by A.D. Baxevanis and B.F.F Ouellette, Wiley interscience. References: Algorithms on Strings, Trees, and Sequences: Computer Science and Computational Biology by D. Gusfield, Cambridge University Press Sequence Analysis in Molecular Biology: Treasure Trove or Trivial Pursuit by G. Von Heijne and G. Von Heijne, Academic Press. Computational Molecular Biology: An Algorithmic Approach by P.A. Pevzner, MIT Press Computer Methods for Macromolecular Sequence Analysis by R.F. Doolittle, J.N, Abelson, M.I. Simon, Academic press Essentials of Genomics and Bioinformatics C.W. Sensen, John Wiley and Sons Inc.
Introduction to Computational Biology: Maps, Sequences and Genomes by M. Waterman, Chapman and Hall Sequence Analysis in Molecular Biology: Treasure Trove or Trivial Pursuit by G. V. Heijne and G.V. Heijne, Academic Press
BIOCHEMISTRY AND MICROBIOLOGY LAB

Course Code: Course Contents:
Module I Preparation of culture media for cultivation of specific microorganism. Isolation of microbes from air, soil and water samples, their identification by staining techniques simple staining, differential Gram staining, lacto phenol cotton blue staining for fungi Module II Biochemical test Indole test, methyl red test, voges proskaeur test, citrate utilization, starch hydrolysis, protease, catalase test and oxidase test. Identification of microbes in water samples; standard plate count, presumptive and confirmed coli form test, BOD and COD Module III Proteins: Identification of protein by Biuret test, quantitation of protein by Bradford method, Separation of proteins by SDS-PAGE, Enzyme: Determination of serum alkaline phosphatase activity Module IV Nucleic Acid: Biochemical estimation of DNA, RNA. Separation of DNAsamples on Agarose gel. Carbohydrate: Color reactions of different type of carbohydrates, Biochemical estimation of blood sugar Lipids: Blood Cholesterol estimation.
MTBPL 10121
Credit Units: 02
Examination Scheme:
Major Experiments: Minor Experiments: Spotting: Viva: Records: Total: 40 20 10 20 10 100
Note: Minor variation could be there depending on the examiner.
INSTRUMENTATION IN BIOTECHNOLOGY LAB

To demonstrate the techniques used in the biotechnology for purification, characterization and identification of the proteins and other biotechnologically important products
MTBPL 10122
Credit Units: 02
Course Contents:
Module I Cell disruption techniques: homogenization, sonication Module II Centrifugation low speed and high speed. Module III Spectrophotometer techniques: Visible and UV spectrophotometry Module IV Chromatography -ion exchange, gel filtration and affinity columns, fraction collection, monitoring UV absorbance. Applications in enzyme purification. Module V Techniques for removal of salt/solvent from a sample -desalting, dialysis, ultrafiltration, speedvac, lyophilization etc. Module VI Electrophoresis 1 D (Polyacryamide gel electrophoresis and agarose) and 2D. Isoelectric focusing. Module VII Polarization and fluorescence microscopy
Examination Scheme:
BIOINFORMATICS LAB
To demonstrate the techniques and soft wares used for sequence analysis, alignment, structure prediction of the proteins and other compounds and finding the phylogenetic relationships
MTBPL 10123
Credit Units: 02
Course Content:
Module I Basics of sequence analysis Retrieving a sequence-nucleic acid/Protein Module II Local and Global Alignment- concepts Pair wise sequence alignment, Multiple sequence alignment Dynamic Programming Smith Watermann Algorithm Needleman Wunsch Algorithm Module III Motif and pattern searching, Structure prediction, Protein structure classification resources, Structure superposition tools, Energy minimization and Simulated annealing Module IV Phylogenetic prediction and analysis Module V Docking small molecules/peptides in active site of protein. Use of automated docking procedures. Free energy calculation. Module VI Finding transcription regulatory signals
Examination Scheme:
TERM PAPER - I
Course Code: MTBTP 10130 Credit Units: 03
A term (or research) paper is primarily a record of intelligent reading in several sources on a particular subject. The students will choose the topic at the beginning of the session in consultation with the faculty assigned. The progress of the paper will be monitored regularly by the faculty. At the end of the semester the detailed paper on the topic will be submitted to the faculty assigned. The evaluation will be done by Board of examiners comprising of the faculties.
GUIDELINES FOR TERM PAPER The procedure for writing a term paper may consist of the following steps:
1. 2. 3. 4. 5. 6. Choosing a subject Finding sources of materials Collecting the notes Outlining the paper Writing the first draft Editing & preparing the final paper
1. Choosing a Subject
The subject chosen should not be too general.
2. Finding Sources of materials

a) The material sources should be not more than 10 years old unless the nature of the paper is such that it involves examining older writings from a historical point of view. b) Begin by making a list of subject-headings under which you might expect the subject to be listed. c) The sources could be books and magazine articles, news stories, periodicals, scientific journals etc.
3. Collecting the notes

Skim through sources, locating the useful material, then make good notes of it, including quotes and information for footnotes. a) Get facts, not just opinions. Compare the facts with author's conclusion. b) In research studies, notice the methods and procedures, results & conclusions. c) Check cross references.
4. Outlining the paper

a) Review notes to find main sub-divisions of the subject. b) Sort the collected material again under each main division to find sub-sections for outline so that it begins to look more coherent and takes on a definite structure. If it does not, try going back and sorting again for main divisions, to see if another general pattern is possible.
5. Writing the first draft

Write the paper around the outline, being sure that you indicate in the first part of the paper what its purpose is. You may follow the following: a) statement of purpose b) main body of the paper c) statement of summary and conclusion Avoid short, bumpy sentences and long straggling sentences with more than one main idea.
6. Editing & Preparing the final Paper

a) Before writing a term paper, you should ensure you have a question which you attempt to answer in your paper. This question should be kept in mind throughout the paper. Include only information/ details/ analyses of relevance to the question at hand. Sometimes, the relevance of a particular section may be clear to you but not to your readers. To avoid this, ensure you briefly explain the relevance of every section. b) Read the paper to ensure that the language is not awkward, and that it "flows" properly. c) Check for proper spelling, phrasing and sentence construction. d) Check for proper form on footnotes, quotes, and punctuation. e) Check to see that quotations serve one of the following purposes: (i) Show evidence of what an author has said. (ii) Avoid misrepresentation through restatement. (iii) Save unnecessary writing when ideas have been well expressed by the original author. f) Check for proper form on tables and graphs. Be certain that any table or graph is self-explanatory.
Term papers should be composed of the following sections: 1) Title page 2) Table of contents 3) Introduction 4) Review 5) Discussion & Conclusion 6) References 7) Appendix Generally, the introduction, discussion, conclusion and bibliography part should account for a third of the paper and the review part should be two thirds of the paper.
Discussion
The discussion section either follows the results or may alternatively be integrated in the results section. The section should consist of a discussion of the results of the study focusing on the question posed in the research paper.
Conclusion
The conclusion is often thought of as the easiest part of the paper but should by no means be disregarded. There are a number of key components which should not be omitted. These include: a) summary of question posed b) summary of findings c) summary of main limitations of the study at hand d) details of possibilities for related future research
References:
From the very beginning of a research project, you should be careful to note all details of articles gathered. The bibliography should contain ALL references included in the paper. References not included in the text in any form should NOT be included in the bibliography. The key to a good bibliography is consistency. Choose a particular convention and stick to this.
Conventions:
Monographs Crystal, D. (2001), Language and the internet. Cambridge: Cambridge University Press.
Edited volumes
Gass, S./Neu, J. (eds.) (1996), Speech acts across cultures. Challenges to communication in a second language. Berlin/ NY: Mouton de Gruyter. [(eds.) is used when there is more than one editor; and (ed.) where there is only one editor. In German the abbreviation used is (Hrsg.) for Herausgeber].
Edited articles
Schmidt, R./Shimura, A./Wang, Z./Jeong, H. (1996), Suggestions to buy: Television commercials from the U.S., Japan, China, and Korea. In: Gass, S./Neu, J. (eds.) (1996), Speech acts across cultures. Challenges to communication in a second language. Berlin/ NY: Mouton de Gruyter: 285-316.
Journal articles:
McQuarrie, E.F./Mick, D.G. (1992), On resonance: A critical pluralistic inquiry into advertising rhetoric. Journal of consumer research 19, 180-197.
Electronic book:
Chandler, D. (1994), Semiotics for beginners [HTML document]. Retrieved [5.10.'01] from the World Wide Web, http://www.aber.ac.uk/media/Documents/S4B/.
Electronic journal articles:

Watts, S. (2000) Teaching talk: Should students learn 'real German'? [HTML document]. German as a Foreign Language Journal [online] 1. Retrieved [12.09.'00] from the World Wide Web, http://www.gfl-journal.com/.
Other websites:
Verterhus, S.A. (n.y.), Anglicisms in German car advertising. The problem of gender assignment [HTML document]. Retrieved [13.10.'01] from the World Wide Web, http://olaf.hiof.no/~sverrev/eng.html.
Unpublished papers:
Takahashi, S./DuFon, M.A. (1989), Cross-linguistic influence in indirectness: The case of English directives performed by native Japanese speakers. Unpublished paper, Department of English as a Second Language,
University of Hawai'i at Manoa, Honolulu.
Unpublished theses/ dissertations:

Mhl, S. (1996), Alltagssituationen im interkulturellen Vergleich: Realisierung von Kritik und Ablehnung im Deutschen und Englischen. Unpublished MA thesis, University of Hamburg. Walsh, R. (1995), Language development and the year abroad: A study of oral grammatical accuracy amongst adult learners of German as a foreign language. Unpublished PhD dissertation, University College Dublin.
Appendix
The appendix should be used for data collected (e.g. questionnaires, transcripts, ...) and for tables and graphs not included in the main text due to their subsidiary nature or to space constraints in the main text.
Assessment Scheme:
Continuous Evaluation: (Based on abstract writing, interim draft, general approach, research orientation, readings undertaken etc.) Final Evaluation: (Based on the organization of the paper, objectives/ problem profile/ issue outlining, comprehensiveness of the research, flow of the idea/ ideas, relevance of material used/ presented, outcomes vs. objectives, presentation/ viva etc.) 40%
60%
COMMUNICATION SKILLS I
The Course is designed to give an overview of the four broad categories of English Communication thereby enhance the learners communicative competence.
MTBBS 10101
Credit Units: 01
Course Contents:
Module I: Listening Skills Effective Listening: Principles and Barriers Listening Comprehension on International Standards Module II: Speaking Skills Pronunciation and Accent Reading excerpts from news dailies & magazines Narrating Incident; Story telling. Extempore & Role Plays Module III: Reading Skills Vocabulary: Synonyms, antonyms, diminutives, homonyms, homophones Idioms & phrases Foreign words in English Module IV: Writing Skills Writing Paragraphs Prcis Writing Letter writing Coherence and structure Essay writing Module V: Activities News reading Picture reading Movie magic Announcements
Examination Scheme:
Components Weightage % C 10 CT 20 P 10 EE 60
Text & References:

Working in English, Jones, Cambridge Business Communication, Raman Prakash, Oxford Speaking Personally, Porter-Ladousse, Cambridge Speaking Effectively, Jermy Comfort, et.al, Cambridge
BEHAVIOURAL SCIENCE - I (SELF-DEVELOPMENT AND INTERPERSONAL SKILLS)

This course aims at imparting an understanding of: Self and the process of self exploration Learning strategies for development of a healthy self esteem Importance of attitudes and their effect on work behavior Effective management of emotions and building interpersonal competence.
MTBBS 10102
Credit Units: 01
Course Contents:
Module I: Understanding Self Formation of self concept Dimension of Self Components of self Self Competency Module II: Self-Esteem: Sense of Worth Meaning and Nature of Self Esteem Characteristics of High and Low Self Esteem Importance & need of Self Esteem Self Esteem at work Steps to enhance Self Esteem Module III: Emotional Intelligence: Brain Power Introduction to EI Difference between IQ, EQ and SQ Relevance of EI at workplace Self assessment, analysis and action plan Module IV: Managing Emotions and Building Interpersonal Competence Need and importance of Emotions Healthy and Unhealthy expression of emotions Anger: Conceptualization and Cycle Developing emotional and interpersonal competence Self assessment, analysis and action plan Module V: Leading Through Positive Attitude Understanding Attitudes Formation of Attitudes Types of Attitudes Effects of Attitude on Behavior Perception Motivation Stress Adjustment Time Management Effective Performance Building Positive Attitude Module VI: End-of-Semester Appraisal Viva based on personal journal Assessment of Behavioral change as a result of training Exit Level Rating by Self and Observer
Text & References:

Towers, Marc: Self Esteem, 1st Edition 1997, American Media
Pedler Mike, Burgoyne John, Boydell Tom, A Managers Guide to Self-Development: Second edition, McGraw-Hill Book company. Covey, R. Stephen: Seven habits of Highly Effective People, 1992 Edition, Simon & Schuster Ltd., Khera Shiv: You Can Win, 1st Edition, 1999, Macmillan Gegax Tom, Winning in the Game of Life: 1st Edition, Harmony Books Chatterjee Debashish, Leading Consciously: 1998 1st Edition, Viva Books Pvt.Ltd., Dr. Dinkmeyer Don, Dr. Losoncy Lewis, The Skills of Encouragement: St. Lucie Press. Singh, Dalip, 2002, Emotional Intelligence at work; First Edition, Sage Publications. Goleman, Daniel: Emotional Intelligence, 1995 Edition, Bantam Books Goleman, Daniel: Working with E.I., 1998 Edition, Bantam Books.
FRENCH - I
To familiarize the students with the French language with the phonetic system with the syntax with the manners with the cultural aspects
MTBFR 10101
Credit Units: 02
Course Contents:
Module A: pp. 01 to 37: Units 1, 2, Unit 3 Objectif 1,2 Only grammar of Unit 3: objectif 3, 4 and 5 Contenu lexical : Unit 1 : Dcouvrir la langue franaise : (oral et crit) 1. se prsenter, prsenter quelquun, faire la connaissance des autres, formules de politesse, rencontres 2. dire/interroger si on comprend 3. Nommer les choses Unit 2 : Faire connaissance 1. donner/demander des informations sur une personne, premiers contacts, exprimer ses gots et ses prfrences 2. Parler de soi: parler du travail, de ses activits, de son pays, de sa ville. Unit 3 : Organiser son temps 1. dire la date et lheure Contenu grammatical : organisation gnrale de la grammaire article indfini, dfini, contract nom, adjectif, masculin, fminin, singulier et pluriel ngation avec de , "moi aussi", "moi non plus" interrogation : Inversion, est-ce que, qui, que, quoi, quest-ce que, o, quand, comment, quel(s), quelle(s) Interro-ngatif : rponses : oui, si, non 6. pronom tonique/disjoint- pour insister aprs une prposition 7. futur proche 1. 2. 3. 4. 5.
Examination Scheme:
Components Weightage (%) V 10 H 10 CT 20 EE 60
Text & References:

le livre suivre : Campus: Tome 1
GERMAN - I
To enable the students to converse, read and write in the language with the help of the basic rules of grammar, which will later help them to strengthen their language. To give the students an insight into the culture, geography, political situation and economic opportunities available in Germany
MTBGR 10101
Credit Units: 02
Course Contents:
Module I: Introduction Self introduction: heissen, kommen, wohnwn, lernen, arbeiten, trinken, etc. All personal pronouns in relation to the verbs taught so far. Greetings: Guten Morgen!, Guten Tag!, Guten Abend!, Gute Nacht!, Danke sehr!, Danke!, Vielen Dank!, (es tut mir Leid!), Hallo, wie gehts?: Danke gut!, sehr gut!, prima!, ausgezeichnet!, Es geht!, nicht so gut!, so la la!, miserabel! Module II: Interviewspiel To assimilate the vocabulary learnt so far and to apply the words and phrases in short dialogues in an interview game for self introduction. Module III: Phonetics Sound system of the language with special stress on Dipthongs Module IV: Countries, nationalities and their languages To make the students acquainted with the most widely used country names, their nationalitie and the language spoken in that country. Module V: Articles The definite and indefinite articles in masculine, feminine and neuter gender. All Vegetables, Fruits, Animals, Furniture, Eatables, modes of Transport Module VI: Professions To acquaint the students with professions in both the genders with the help of the verb sein. Module VII: Pronouns Simple possessive pronouns, the use of my, your, etc. The family members, family Tree with the help of the verb to have Module VIII: Colours All the color and color related vocabulary colored, colorful, colorless, pale, light, dark, etc. Module IX: Numbers and calculations verb kosten The counting, plural structures and simple calculation like addition, subtraction, multiplication and division to test the knowledge of numbers. Wie viel kostet das? Module X: Revision list of Question pronouns W Questions like who, what, where, when, which, how, how many, how much, etc.
Examination Scheme:
Components Weightage (%) CT-1 15 CT-2 15 H-1 + V-1 10 EEI 60
Text & References:

Wolfgang Hieber, Lernziel Deutsch Hans-Heinrich Wangler, Sprachkurs Deutsch Schulz Griesbach , Deutsche Sprachlehre fr Auslnder P.L Aneja , Deutsch Interessant- 1, 2 & 3
Rosa-Maria Dallapiazza et al, Tangram Aktuell A1/1,2 Braun, Nieder, Schme, Deutsch als Fremdsprache 1A, Grundkurs
SPANISH I
To enable students acquire the relevance of the Spanish language in todays global context, how to greet each other. How to present / introduce each other using basic verbs and vocabulary
MTBSH 10101
Credit Units: 02
Course Contents:
Module I A brief history of Spain, Latin America, the language, the cultureand the relevance of Spanish language in todays global context. Introduction to alphabets Module II Introduction to Saludos (How to greet each other. How to present / introduce each other). Goodbyes (despedidas) The verb llamarse and practice of it. Module III Concept of Gender and Number Months of the years, days of the week, seasons. Introduction to numbers 1-100, Colors, Revision of numbers and introduction to ordinal numbers. Module IV Iintroduction to SER and ESTAR (both of which mean To Be).Revision of Saludos and Llamarse. Some adjectives, nationalities, professions, physical/geographical location, the fact that spanish adjectives have to agree with gender and number of their nouns. Exercises highlighting usage of Ser and Estar. Module V Time, demonstrative pronoun (Este/esta, Aquel/aquella etc) Module VI Introduction to some key AR /ER/IR ending regular verbs.
Examination Scheme:
Components Weightage (%) C-1 10 CT 20 V 10 EEI 60
Text & References:

Espaol, En Directo I A Espaol Sin Fronteras
JAPANESE - I
To enable the students to learn the basic rules of grammar and Japanese language to be used in daily life that will later help them to strengthen their language.
MTBJP 10101
Credit Units: 02
Course Contents:
Module I: Salutations Self introduction, Asking and answering to small general questions Module II: Cardinal Numbers Numerals, Expression of time and period, Days, months Module III: Tenses Present Tense, Future tense Module IV: Prepositions Particles, possession, Forming questions Module V: Demonstratives Interrogatives, pronoun and adjectives Module VI: Description Common phrases, Adjectives to describe a person Module VII: Schedule Time Table, everyday routine etc. Module VIII: Outings Going to see a movie, party, friends house etc.
Learning Outcome
Students can speak the basic language describing above mentioned topics
Methods of Private study /Self help

Handouts, audio-aids, and self-do assignments and role-plays will support classroom teaching
Examination Scheme:
Text & References:

Text: Teach yourself Japanese. References: Shin Nihongo no kiso 1
CHINESE I
There are many dialects spoken in China, but the language which will help you through wherever you go is Mandarin, or Putonghua, as it is called in Chinese. The most widely spoken forms of Chinese are Mandarin, Cantonese, Gan, Hakka, Min, Wu and Xiang. The course aims at familiarizing the student with the basic aspects of speaking ability of Mandarin, the language of Mainland China. The course aims at training students in practical skills and nurturing them to interact with a Chinese person.
MTBCE 10101
Credit Units: 02
Course Contents:
Module I Show pictures, dialogue and retell. Getting to know each other. Practicing chart with Initials and Finals. (CHART The Chinese Phonetic Alphabet Called Hanyu Pinyin in Mandarin Chinese.) Practicing of Tones as it is a tonal language. Changes in 3rd tone and Neutral Tone. Module II Greetings Let me Introduce The modal particle ne. Use of Please qing sit, have tea .. etc. A brief self introduction Ni hao ma? Zaijian! Use of bu negative. Module III Attributives showing possession How is your Health? Thank you Where are you from? A few Professions like Engineer, Businessman, Doctor, Teacher, Worker. Are you busy with your work? May I know your name? Module IV Use of How many People in your family? Use of zhe and na. Use of interrogative particle shenme, shui, ma and nar. How to make interrogative sentences ending with ma. Structural particle de. Use of Nin when and where to use and with whom. Use of guixing. Use of verb zuo and how to make sentences with it. Module V Family structure and Relations. Use of you mei you. Measure words Days and Weekdays. Numbers. Maps, different languages and Countries.
Examination Scheme:
Components Weightage (%) V 10 H 10 CT 20 EEI 60
Text & References:

Elementary Chinese Reader Part I Lesson 1-10
CELL AND MOLECULAR BIOLOGY

Course Code: Course Objectives:
The object of the present course is to develop basic knowledge and skills in cell and molecular biology and to understand the structure and function of the cellular and sub cellular components of cells and tissues with the help of recent techniques. This course will help students to get an understanding of cell function at the molecular level including the fundamentals of DNA They will become aware of the complexity and harmony of the cell. Applications of cellular and molecular biology in Biotechnology will also be presented.
MTBBT 10201
Credit Units: 04
Course Contents:
Module I Protein targeting - Chemical and physical properties of cell membranes and their major components, significance of these properties to membrane structure, integral and peripheral membrane proteins, biosynthesis of membrane and secreted proteins; targeting of proteins to membranes. Module II Membrane transport/Cell Cycle - Mechanisms for transport of small molecules across the membrane, including simple diffusion, facilitative diffusion, primary and secondary active transport, action of ionophores. Cell cycle and the events associated with each stage, control of the cell cycle and the proteins involved; know the role of the cyclins and cyclin-dependent kinases, cell cycle checkpoints, methods for synchronizing the cell cycle in cell populations. Module III Intracellular Signaling I -define growth, growth factor, growth factor receptor, mitogen, receptor, effector, second messenger, action of hormones and other biologically active agents that act via receptors in the nucleus and/or cytoplasm. Intracellular Signaling II - the intracellular signaling cascades triggered by hormone binding to these receptor, G proteins signalling, the action of Ca 2+ and diacylglycerol as second messengers. Module IV Replication: Replication of DNA, Role of DNA polymerases & proteins involved in DNA replication, Compare and contrast eukaryote and prokaryote DNA replication, telomeres, telomerase and altered telomerase function in aging and disease. Recombination & Repair: Mutations and types of site mutations: substitution, transition, transversion, insertion, deletion, tautomer, frameshift and nonsense mutation. Repair mechanisms: dimer repair, excision repair, mismatch repair, trans-lesion repair, and recombinational repair. Module V Transcription - RNA transcription and the proteins required for each step, maturation of the RNA transcript derived from a eukaryotic gene, structure of prokaryote and eukaryote promoter and the function of promoter sequences, inhibitors of prokaryote and eukaryote transcription and their mechanisms of action. Concept of operon, inducer, operator and polycistronic transcript, expression of the lac operon and trp operon in E. coli, catabolite repression, leader peptide and attenuator site, enhancer and transcription factors, four common DNAbinding motifs found in transcription factors, mRNA stability and alternative splicing in gene expression Module VI Translation: Genetic code and the concept of colinearity of the gene and protein, components required for translation, basic steps involved in initiation, elongation, and termination of protein translation, inhibitors of protein translation. Compare and contrast the spatial and temporal differences in prokaryotic and eukaryotic transcription and translation
Examination Scheme:
Text & References:

Text: Molecular Cell Biology by Bruce Albert Molecular Biology by Lodish Darnell and Baltimore Molecular Biology of the gene by Watson et al 4th ed.
References: Genes VIII by Benjamin Lewis Genetics by Ursula Goodenough Cytogenetics by lGarl P. Swanson, Mertz & Young Biochemistry by Stryer Genome by T.A. Brown, John Willey and Sons Inc.
RECOMBINANT DNA TECHNOLOGY

A complete understanding of molecular techniques like DNA sequencing, restriction mapping, PCR for the cloning and expression of genes implication can be obtained through the course. The successful application of biotechnology largely depends on these advanced molecular techniques.
MTBBT 10202
Credit Units: 04
Course Contents:
Module I Basic tools, specialized enzymes and specialized cloning vectors (e.g. Antarctic Phosphatase), Specialized cloning vectors (e.g. TOPO, TA, Gateway) Module II Gene isolation: Expression libraries and their screening, Techniques for analysis of genomic libraries (e.g. 3 RACE, 5 RACE, chromosome walking, chromosome jumping), T-DNA and transposon mediated gene traps Module III Heterologous gene expression (bacteria and yeast): Advances in engineering of genes (codon optimization, translational enhancers, mRNA stabilizing factors), vectors (targeting signals, selection markers, purification and solubility tags) and hosts for overexpression and analysis Module IV Studying gene regulation and control: In-vitro transcription translation, run-on assays, protein-protein and protein-DNA interactions, promoter characterization, differential display. Manipulation of gene expression: Genome wide mutagenesis, gene silencing, RNAi, aptamers, constitutive and tissue specific promoters, expression enhancing elements, terminator technology Module V Automation and robotic advances in RDT: DNA & protein isolation (alternatives to conventional methods) and sequencing (example from Human Genome Project and other sequencing projects), PCR machines, imaging and gel documentation Module VI Laboratory, industrial and environmental applications of RDT: High throughput research, disease diagnosis and cure, forensics, DNA vaccines, drug discovery, maintaining genetic diversity, transgenic technology, markerfree GMOs
Examination Scheme:
Text & References:

Text: Recombinant DNA by J.D. Watson et al., W.H. Freeman and Company Recombinant DNA Technology by T. A. Brown Genes to Clone by Winnaker References: Principles of Gene Manipulation: An Introduction to Genetic Engineering by R.W. Old and S. B Primrose, Blackwell Science Inc Molecular Biotechnology: Principles and Applications of Recombinant DNA by B.R. Grick and J.J. Pasternak, ASM Press Molecular and Cellular Cells Methods in Biology and Medicine by P.B. Kaufman, W. Wu, D. Kim and C.J. Cseke, CRC Press. Milestones in Biotechnology: Classic Papers on Genetic Engineering by J.A. Bavies and W.S. Reznikoff, Butterworth Heinemann. Gene Expression Technology by D.V. Goeddel in Methods in Methods in Enzymology, Academic Press Inc. DNA Cloning: A Practical Approach by D.M. Glover and B.D. Hames, IRL Press.
BIOPROCESS TECHNOLOGY
The present course aims to aware about the requirements for large-scale cultivation of microbes for production of industrially important products with purification and characterization of these bioproducts using different techniques
MTBBT 10203
Credit Units: 04
Course Contents:
Module I Introduction to Bioprocess Technology, Microbial growth kinetics. Module II Substrates for bioconversion processes and design of media, sterilization; Cell culture techniques; Inoculum development and aseptic transfers. Bioreactors Types and Design, different types of pumps, valves, valves and line materials, piping convections etc. used in Biochemical Processes Module III Process technology for the production of primary metabolites, e.g. Bakers yeast, ethanol, citric acid, amino acids (lysine and glutamic acid). Microbial production of industrial enzymes (glucose isomerase, cellulase, amylase, lipase, protease) and secondary metabolites (penicillins, cephalosporins and streptomycin). Biomass ( SCP and mushroom) production from agro-residues. Enzyme and Enzyme kinetics: Key characteristics of an enzyme, enzymes as catalysts, basic concepts of thermodynamics as they apply to chemical reactions, Michaelis-Menten equation, reversible and irreversible enzyme inhibition, effects of competitive and noncompetitive inhibitors on the K mand Vmax of the treated enzyme, allosteric enzyme, kinetics of allosteric enzymes to enzymes observing Michaelis- Menten kinetics, Catalytic strategies used in enzyme reactions. Module IV Characteristics of bioproducts, Conditioning of broth, Mechanical separation, Filtration, Centrifugation, Cell disruption techniques, Protein precipitation and separation Module V Aqueous-two-phase extraction; Adsorption-desorption processes; Membrane based separation: Dialysis, Electro dialysis, Micro filtration, Ultra filtration
Examination Scheme:
Text & References:

Text: Biotechnology. A Textbook of Industrial Microbiology, W. Crueger and a. Crueger, Sinauer Associates. Principles of Fermentation Technology, P.F. Stanbury and A. Whitaker, Pergamon Press Bioseparations: Downstream Processing for Biotechnology, P.A. Belter et al, John Wiley and Sons Inc. References: Bioprocess Technology: Fundamentals and Applications, KTH, Stockholm. Biochemical Engineering Kinetics, Mass Transport, Reactors and Gene Expression, W.F. Veith, John Wiley and Sons Inc. Biochemical Engineering, S. Aiba, A.E. Humphrey and N.F. Millis, University of Tokyo Press Bioprocess Engineering, B.K. Lydersen, K.L. Nelson, B.K. Lyderson and N. DElia, John Wiley and Sons Inc. Process Engineering in Biotechnology, A.T. Jackson, Prentice Hall Practical Biochemistry, Principles & Techniques, Keith Wilson and John Walker Biotreatment, Downstream Processing and Modelling (Advances in Biochemical Engineering / Biotechnology, Vol 56), T. Scheper et al, Springer Verlag Chromatographic and Membrane Processes in Biotechnology, C.A. Costa and J.S. Cabral, Kluwer Academic Publisher Downstream Processing, J.P. Hamel, J.B. Hunter and S.K. Sikdar, American Chemical Society Protein Purification, M.R. Lodisch, R.C. Wilson, C.C. Painton and S.E. Builder, American Chemical Society
ARTIFICIAL NEURAL NETWORKS

Course Code: Course objective:
This course will enable the students to gain knowledge about a relatively newer area of science. The course is designed to model the different technical properties, applications, besides the closely related aspects of artificial neural networks.
MTBBT 10204
Credit Units: 04
Course Contents:
Module I Historical background, Why is learning hard?. Module II Memorization, generalization and function approximation, Linear Associators, Perceptrons and Capacity, Multilayer neural networks, Maximum Likelihood and Gradient Descent learning, Stochastic gradient descent for supervised learning. Module III The back propagation algorithm, Aspects of Learning Theory and Generalization, Bias vs. variance, Overtraining, pruning and regularization, VC dimension and how much data is enough?. Module IV Neural networks and analog VLSI, Selected Applications.
Examination Scheme:
Text & References:

Text: Neural Networks: A Comprehensive Foundation by S. Haykin, Prentice Hall. References: Neutral Networks for Pattern Recognition by C. Bishop, Oxford University Press.
BIOSENSORS
Course Code: Course objectives:
On completion of the module students should Be able to Appreciate the basic configuration and distinction among biosensor systems, To gain an understanding of general biosensor principles and terms, To be able to design, model, simulate, fabricate, and test a biosensor, To gain an overall knowledge of biosensor types, applications, requirements, and capabilities to allow improved interaction with physicians, clinicians, and biomedical engineers, and to enable the student to conduct biomedical engineering research.
MTBBT 10205
Credit Units: 04
Course Contents:
Module I Introduction to MEMS Module II Biosensors: Definition, History, Properties of biosensors, Design features of Biosensors, The Biological Component, Signal Transduction: Amperometric Biosensors, Potentiometric Biosensors, Detection of H+ cation, Detections of NH4+ cation, Detection of CN- anion, Calorimetric biosensors, Optical Biosensors, Measuring the change in light reflectance, Measuring luminescence, Pizo-electric biosensors, Immunosensors, Commercial examples of biosensors. Biosensors markets- Opportunities and obstacles. Module III Biomedical sensors: Sensors and transducers: an overview, measurement systems, Classification of Biomedical sensors and transducers, who do we need Biomedical sensors and Transducers? Important Design considerations and system calibration, the future of Biosensors and Transducers, Sensing Layer: The importance of computers in sensors and Transducer technology, Recent Engineering Solutions to Health care using Biosensors and Transducers, Modern health care solutions.
Examination Scheme:
Text & References:

Text: Affinity Biosensors: Techniques and Protocol by K.R. Rogers and A. Mulchandani, Humana Press. Biosensors and their Applications by V.C. Yang and T.T. Ngo, Plenum Publishing Corporation. Chemical Sensors and Biosensors by B.R. Eggins, John Wiley and Sons Inc. References: Sensors and Sensing in Biology and Engineering by F.G. Barth, wt al, Springer Verlag. Biosensors by Minh Canh. Tran Biosensors: Theory and Applications by Donald G. Buerk Enzyme and Microbial Biosensors: : Techniques and Protocols - by Kim R.Rogers, Ashok Mulchandani Biosensors in Environmental Monitoring - by Ursula Bilitewski, Anthony P. F. Turner. Biosensors: Microelectrochemical Devices - by Marc J. C. Lambrechts Biosensors with Fiberoptics - by Donald Lee Wise, Lemuel B. Wingard Biosensors and Their Applications - by That Tjien Ngo, Victor Chi-Min Yang Thermal Biosensors, Bioactivity, Bioaffinity -by Prakash K. Bhatia Novel Approaches in Biosensors and Rapid Diagnostic Assays - by Zvi Liron, Avraham Bromberg, Morly Fisher Biosensors - by Anthony E. G. Cass.
ENVIRONMENTAL BIOTECHNOLOGY
Course Code: Course objective:
To introduce the students to regenerate clean environment using biotechnology as the key tool and provide them the insight for eco-friendly approach along with the concept of sustainable development.
MTBBT 10206
Credit Units: 04
Course Contents:
Module I Environmental components, Natural resources, Ecosystem and its diversity, Environmental pollution and its major impacts, Global warming and greenhouse effect, Global Ozone Problem, Acid rain, Eutrophication, Land degradation, Biomagnification Module II Non-renewable and renewable energy resources, concept of clean fuel technology, Biomass energy and biofuels Module III Biodegradation and bioremediation of major pollutants, Biomineralisation: Use of microbial technology for mining Module IV Waste water engineering: Treatment of municipal wastes and industrial effluents with special focus on use of biological methods, Advanced waste water treatments Module V Bioassessment of environmental quality: Biosensors and biomarkers, Biofertilizers, Biopesticides and Vermi composting Module VI Environmental impact assessment and Environmental audit, Related case studies from Indian market
Examination Scheme:
Text & References:

Text: Environmental Science, S.C. Santra Environmental Biotechnology, Pradipta Kumar Mohapatra References: Environmental Biotechnology Concepts and Applications by Hans-Joachim Jordening and Jesef Winter Waste Water Engineering by Metcalf and Eddy. Publisher: Tata McGraw hill Environmental Microbiology: Methods and Protocols by Alicia L. Ragout De Spencer, John F.T. Spencer Introduction to Environmental Biotechnology by Milton Wainwright Principles of Environmental Engineering by Gilbert Masters
AGRICULTURE BIOTECHNOLOGY
This course is designed to cover key concepts in the structure and manipulation of DNA and inheritance of genes, traditional plant breeding, current impact of biotechnology on crop production and its commercial applications. Regeneration of plants through in vitro techniques offers a practical strategy for micro propagation.
MTBBT 10207
Credit Units: 04
Course Contents:
Module I Plant Tissue Culture: Sterilization; Nutrient medium; Callus & Suspension culture; canning, regulation; somatic embryogenesis, anther culture; ovary culture; meristem culture; somatic hybridization, embryo culture; in vitro pollination. Cyropreservation and slow growth culture Module II Plant Biotech: Agar culture; suspension culture; biochemical production; microprapagation; virus free culture; somaclonal variation; haploid plants, embryo rescue; somatic hybrids; cybrids, germplasm conservation, molecular markers & maps. Module III Transgenic Plants: Gene Construct; vectors (Plasmid vectors; Plant virus vector), Transformation; agroinfection; directgene transfer; inheritance of transgenic. Module IV Application : Insect resistance; virus resistance; seed protein quality; suppression of endogenous genes; male sterility; biochemical ; problems gene transfer; safety regulation and transgenic plants. Module V Stress Resistance Plant: Salt tolerance, freezing tolerances, chilling tolerance, and drought & food tolerance. Module VI Crops-packages practice. Principle of crop production.
Examination Scheme:
Text & References:

Text: Plant Cell & Tissue Culture for the production of Food Ingredients bt T-J Fu, G. Singh and W.R. Curtis. Kluwer
Adacemic/Plenum Press Plant Biotechnology and Transgenic Plants, K.M.O. Caldenty, W.H. Barz and H.L. Wills, Marcel Dekker
References: An Introduction to Plant Tissue Culture, M.K. Razdan, Oxford and IBH Publishing Experiments in Plant Tissue Culture, J.H. Dodds and L.K. Roberts, Cambridge University Press Plant Biotechnology, J. Hammond, P. McGarvy and V. Yusibov, Springer Verlag. Plant Tissue Culture: Theory & Practice, S.S. Bhojwani and M.K. Razdan, Elsevier Health Sciences
FUNDAMENTALS OF COMPUTERS AND PROGRAMMING IN C

The main objectives of the course are to demonstrate familiarity with computer, show understanding of computer hardware and software, display basic understanding of computer programming processes, develop understanding of computer file management and protection principles, explain Internet, LAN and digital media fundamentals, define information systems analysis and design concepts, identify and demonstrate use of database concepts.
MTBBT 10208
Credit Units: 04
Course Contents:
Module I Introduction to Digital Computer: Major components of a Digital Computer - Number system - Binary codes Fixed and Floating Point representation - Logic gates - Flip flops - Registers - Input and Output Devices. Module II Introduction to programming: Flow charts and algorithms - Fundamentals of 'C' Language - Typical structure of a C Program. Module III Data Types: Variables - Constants - Arithmetic expressions - Use of operators - program examples. Module IV Decision making in C: Relational operators - Logical operators - Precedence of operators - IF and IF ... ELSE statements Looping concepts in C _ WHILE loop - DO ... WHILE and FOR loops - Programming examples. Functions: User defined Functions - Local and Global variables - Parameters - Programming examples. Module V Arrays: BREAK statement - Strings and character arrays - examples.. Pointers: Concept of Pointers - The Indirection operator - Use of Pointers in arrays - Programming examples. Module VI Structures : The period operator - Arrays of structures - Arrays within structures - Structures within structures Pointers to structures - The arrow operator - Programming examples.
Examination Scheme:
Text & References:

Text: Fundamentals of Computers by V.Rajaraman C Programming" by G. Kochan References: Computer Fundamentals by B.Ram. The Spirit of C" by Mullish Cooper.
IPR, BIOSAFETY AND BIOETHICS

The objectives of the course are to explain the fundamental principles of IPR issues and examine information policy issues from different perspectives. Students will study and assess policy groups, intellectual property rights, access to information and research policy issues that usually include plant, animal and microbial genetic engineering products
MTBBT 10209
Credit Units: 04
Course Contents:
Module I Objectives of Intellectual Property Rights, origin and evolution of IPR, tangible and intangible property; concept and classification of intellectual property: Copyrights and related rights, Patent, Industrial Design, Trademarks and Geographical indications, Rights of traditional Knowledge and Protection of Plant varieties Module II IPR : National and international perspective , TRIPS and WIPO Module III Patent: basic criterion for patentability, patentable subjects, patentable inventions, patent acquisition, infringement of patent, discovery Vs invention, product patenting Vs process patenting, special issue in biotechnology patent, Patenting laws in Indian and international perspective, Case study: Basmati case, Neem controversy, Turmeric Case Module IV Biosafety: definition and requirement; biosafety in relation to human health, environment, transgenic research and applications, biosafety laws, guidelines and conventions, biosafety regulation: principles and practices in microbial and biomedical labs, guidelines for research involving DNA molecule ; Regulation bodies at National and International level Module V Legal and socioeconomic impact of the products and techniques in Biotechnology, Bioethics in plant, animal and microbial genetic engineering, Ethical issues in healthcare, Biopiracy and ethical conflicts
Examination Scheme:
Text & References:

Text: Coyles information highway handbook; A Practical File on the New Information Order, American Library Association, 2000. American Indian Cultural & Research Journal (UCLA) References: Refer to Periodicals, Industry directories, Articles and report in journals on the regulatory issues, Biotechnology series by Rehm & Reed.
CELL, MOLECULAR BIOLOGY & RECOMBINANT DNA TECHNOLOGY LAB

Course Code:
Course Objective:
The laboratory experiments in Recombinant DNA Technology would certainly help to comprehend the theoretical aspects of the subject.
MTBPL 10221
Credit Units: 03
Course Contents:
Module I Isolation of plasmid and chromosomal DNA, Restriction digestion of plasmid DNA and construction of restriction map, Ligation and Cloning in plasmid /phagemid vectors. Module II Preparation and Transformation of competent cells by CaCl2 method. Module III Blotting and Hybridization techniques. Module IV DNA amplification by PCR method Module V Gene expression in E.coli and Analysis of gene product, Reporter Gene assay/ (Gus/CAT/b-GAL) Module VI Site-directed mutagenesis
Examination Scheme:
BIOPROCESS TECHNOLOGY LAB

The present course aims to acquaint the students with lab-scale cultivation of microbes for production of industrially important products with the concept of scale up processes and to extract different bioproducts during their characterization.
MTBPL 10222
Credit Units: 03
Course Contents:
Module I Isolation of industrially important micro organisms for microbial processes. Module II Determination of growth curve of a supplied micro organism and also determine substrate degradation profile and to compute specific growth rate and growth yield from the data obtained. Module III Comparative studied of ethanol production using different substrates, Production and estimation of alkaline protease, Microbial production of antibiotics (Penicillin) Module IV Conventional filtration and membrane based filtration, Aqueous two-phase separation, Ion exchange chromatography, Gel Permeation chromatography
Examination Scheme:
TERM PAPER - II
1. 2. 3. 4. 5. Choosing a subject Finding sources of materials Collecting the notes Outlining the paper Writing the first draft 6. Editing & preparing the final paper

d) The material sources should be not more than 10 years old unless the nature of the paper is such that it involves examining older writings from a historical point of view. e) Begin by making a list of subject-headings under which you might expect the subject to be listed. f) The sources could be books and magazine articles, news stories, periodicals, scientific journals etc.

Skim through sources, locating the useful material, then make good notes of it, including quotes and information for footnotes. d) Get facts, not just opinions. Compare the facts with author's conclusion. e) In research studies, notice the methods and procedures, results & conclusions. f) Check cross references.

c) Review notes to find main sub-divisions of the subject. d) Sort the collected material again under each main division to find sub-sections for outline so that it begins to look more coherent and takes on a definite structure. If it does not, try going back and sorting again for main divisions, to see if another general pattern is possible.


g) Before writing a term paper, you should ensure you have a question which you attempt to answer in your paper. This question should be kept in mind throughout the paper. Include only information/ details/ analyses of relevance to the question at hand. Sometimes, the relevance of a particular section may be clear to you but not to your readers. To avoid this, ensure you briefly explain the relevance of every section. h) Read the paper to ensure that the language is not awkward, and that it "flows" properly. i) Check for proper spelling, phrasing and sentence construction. j) Check for proper form on footnotes, quotes, and punctuation. k) Check to see that quotations serve one of the following purposes: (iv) Show evidence of what an author has said. (v) Avoid misrepresentation through restatement. (vi) Save unnecessary writing when ideas have been well expressed by the original author. l) Check for proper form on tables and graphs. Be certain that any table or graph is self-explanatory.
Discussion
Conclusion
The conclusion is often thought of as the easiest part of the paper but should by no means be disregarded. There are a number of key components which should not be omitted. These include: e) summary of question posed f) summary of findings g) summary of main limitations of the study at hand h) details of possibilities for related future research
References:
Conventions:
Edited volumes
Edited articles
Journal articles:
Electronic book:

Other websites:
Unpublished papers:
Unpublished theses/ dissertations:

Appendix
Assessment Scheme:
60%
COMMUNICATION SKILLS - II
To enrich the understanding of English language and communication, structure, style, usage, and vocabulary for global business purposes.
MTBBS 10201
Credit Units: 01
Course Contents:
Module I: Fundamentals of Communication Role and purpose of communication: 7 Cs of communication Barriers to effective communication Enhancing listening Forms of Communication: one-to-one, informal and formal Module II: Verbal Communication (Written) Business Letter Social correspondence Writing resume and Job applications Module III: Speaking skills Conversational English Guidelines to give an effective presentation Activities to include: Presentations by students Just a minute
Examination Scheme:
Components Weightage % C CT P EE
10
20
10
60
Text & References:

Business Communication, Raman Prakash, Oxford Textbook of Business Communication, Ramaswami S, Macmillan Speaking Personally, Porter-Ladousse, Cambridge
BEHAVIOURAL SCIENCE - II (BEHAVIOURAL COMMUNICATION AND RELATIONSHIP MANAGEMENT)

This course aims at imparting an understanding of: Process of Behavioral communication Aspects of interpersonal communication and relationship Management of individual differences as important dimension of IPR
MTBBS 10202
Credit Units: 01
Course Contents:
Module I: Behavioral Communication Scope of Behavioral Communication Process Personal, Impersonal and Interpersonal Communication Guidelines for developing Human Communication skills Relevance of Behavioral Communication in relationship management Module II: Managing Individual Differences in Relationships Principles Types of issues Approaches Understanding and importance of self disclosure Guidelines for effective communication during conflicts Module III: Communication Climate: Foundation of Interpersonal Relationships Elements of satisfying relationships Conforming and Disconfirming Communication Culturally Relevant Communication Guideline for Creating and Sustaining Healthy Climate Module IV: Interpersonal Communication Imperatives for Interpersonal Communication Models Linear, Interaction and Transaction Patterns Complementary, Symmetrical and Parallel Types Self and Other Oriented Steps to improve Interpersonal Communication Module V: Interpersonal Relationship Development Relationship circle Peer/ Colleague, Superior and Subordinate Initiating and establishing IPR Escalating, maintaining and terminating IPR Direct and indirect strategies of terminating relationship Model of ending relationship Module VI: End-of-Semester Appraisal Viva based on personal journal Assessment of Behavioral change as a result of training Exit Level Rating by Self and Observer
Text & References:

Vangelist L. Anita, Mark N. Knapp, Inter Personal Communication and Human Relationships: Third Edition, Allyn and Bacon Julia T. Wood. Interpersonal Communication everyday encounter Simons, Christine, Naylor, Belinda: Effective Communication for Managers, 1997 1st Edition Cassell Harvard Business School, Effective Communication: United States of America Beebe, Beebe and Redmond; Interpersonal Communication, 1996; Allyn and Bacon Publishers.
FRENCH - II
To enable the students to overcome the fear of speaking a foreign language and take position as a foreigner speaking French. To make them learn the basic rules of French Grammar.
MTBFR 10201
Credit Units: 02
Course Contents:
Module A : pp.38 47 : Unit 3 : Objectif 3, 4, 5. 6 Module B: pp. 47 to 75 Unit 4, 5 Contenu lexical: Unit 3 : Organiser son temps 1. donner/demander des informations sur un emploi du temps, un horaire SNCF Imaginer un dialogue 2. rdiger un message/ une lettre pour i) prendre un rendez-vous/ accepter et confirmer/ annuler ii) inviter/accepter/refuser 3. Faire un programme dactivits imaginer une conversation tlphonique/un dialogue Propositions- interroger, rpondre Unit 4: Dcouvrir son environnement 1. situer un lieu 2. sorienter, sinformer sur un itinraire. 3. Chercher, dcrire un logement 4. connatre les rythmes de la vie Unit 5 : sinformer 1. demander/donner des informations sur un emploi du temps pass. 2. donner une explication, exprimer le doute ou la certitude. 3. dcouvrir les relations entre les mots 4. savoir sinformer Contenu grammatical: 1. Adjectifs dmonstratifs 2. Adjectifs possessifs/exprimer la possession laide de : i. de ii. A+nom/pronom disjoint 3. Conjugaison pronominale ngative, interrogative construction l'infinitif 4. Impratif/exprimer lobligation/linterdiction laide de il faut. / il ne faut pas 5. pass compos 6. Questions directes/indirectes
Examination Scheme:
Text & References:

GERMAN II
To enable the students to converse, read and write in the language with the help of the basic rules of grammar, which will later help them to strengthen their language. To give the students an insight into the culture, geography, political situation and economic opportunities available in Germany Introduction to Grammar to consolidate the language base learnt in Semester I
MTBGR 10201
Credit Units: 02
Course Contents:
Module I: Everything about Time and Time periods Time and times of the day. Weekdays, months, seasons. Adverbs of time and time related prepositions Module II: Irregular verbs Introduction to irregular verbs like to be, and others, to learn the conjugations of the same, (fahren, essen, lessen, schlafen, sprechen und hnliche). Module III: Separable verbs To comprehend the change in meaning that the verbs undergo when used as such Treatment of such verbs with separable prefixes Modules IV: Reading and comprehension Reading and deciphering railway schedules/school time table Usage of separable verbs in the above context Module V: Accusative case Accusative case with the relevant articles Introduction to 2 different kinds of sentences Nominative and Accusative Module VI: Accusative personal pronouns Nominative and accusative in comparison Emphasizing on the universal applicability of the pronouns to both persons and objects Module VII: Accusative prepositions Accusative propositions with their use Both theoretical and figurative use Module VIII: Dialogues Dialogue reading: In the market place At the Hotel
Examination Scheme:
Text & References:

Wolfgang Hieber, Lernziel Deutsch Hans-Heinrich Wangler, Sprachkurs Deutsch Schulz Griesbach , Deutsche Sprachlehre fr Auslnder P.L Aneja , Deutsch Interessant- 1, 2 & 3 Rosa-Maria Dallapiazza et al, Tangram Aktuell A1/1,2 Braun, Nieder, Schme, Deutsch als Fremdsprache 1A, Grundkurs
SPANISH II
To enable students acquire more vocabulary, grammar, Verbal Phrases to understand simple texts and start describing any person or object in Simple Present Tense.
MTBSH 10201
Credit Units: 02
Course Contents:
Module I Revision of earlier modules. Module II Some more AR/ER/IR verbs. Introduction to root changing and irregular AR/ER/IR ending verbs Module III More verbal phrases (eg, Dios Mio, Que lastima etc), adverbs (bueno/malo, muy, mucho, bastante, poco). Simple texts based on grammar and vocabulary done in earlier modules. Module IV Posessive pronouns Module V Writing/speaking essays like my friend, my house, my school/institution, myself.descriptions of people, objects etc, computer/internet related vocabulary
Examination Scheme:
Text & References:

Espaol, En Directo I A, Espaol Sin Fronteras
JAPANESE - II
To enable the students to converse in the language with the help of basic particles and be able to define the situations and people using different adjectives.
MTBJP 10201
Credit Units: 02
Course Contents:
Module I: Verbs Transitive verbs, intransitive verbs Module II: More prepositions More particles, articles and likes and dislikes. Module III: Terms used for instructions No parking, no smoking etc. Module IV: Adverbs Different adverbial expression. Module V: Invitations and celebrations Giving and receiving presents, Inviting somebody for lunch, dinner, movie and how to accept and refuse in different ways Module VI: Comprehensions Short essay on Family, Friend etc. Module VII: Conversations Situational conversations like asking the way, At a post office, family Module VIII: Illness Going to the doctor, hospital etc.
Learning Outcome
Students can speak the language describing above-mentioned topics.

Handouts, audio-aids, and self-do assignments. Use of library, visiting and watching movies in Japan and culture center every Friday at 6pm.
Examination Scheme:
Text & References:

Text: Teach yourself Japanese References: Shin Nihongo no kiso 1
CHINESE II
Chinese is a tonal language where each syllable in isolation has its definite tone (flat, falling, rising and rising/falling), and same syllables with different tones mean different things. When you say, ma with a third tone, it mean horse and ma with the first tone is Mother. The course aims at familiarizing the student with the basic aspects of speaking ability of Mandarin, the language of Mainland China. The course aims at training students in practical skills and nurturing them to interact with a Chinese person.
MTBCE 10201
Credit Units: 02
Course Contents:
Module I Drills Practice reading aloud Observe Picture and answer the question. Tone practice. Practice using the language both by speaking and by taking notes. Introduction of basic sentence patterns. Measure words. Glad to meet you. Module II Where do you live? Learning different colors. Tones of bu Buying things and how muchit costs? Dialogue on change of Money. More sentence patterns on Days and Weekdays. How to tell time. Saying the units of time in Chinese. Learning to say useful phrases like 8:00, 11:25, 10:30 P.M. everyday, afternoon, evening, night, morning 3:58, one hour, to begin, to end .. etc. Morning, Afternoon, Evening, Night. Module III Use of words of location like-li, wais hang, xia Furniture table, chair, bed, bookshelf,.. etc. Description of room, house or hostel room.. eg what is placed where and how many things are there in it? Review Lessons Preview Lessons. Expression yao, xiang and yaoshi (if). Days of week, months in a year etc. I am learning Chinese. Is Chinese difficult? Module IV Counting from 1-1000 Use of chang-chang. Making an Inquiry What time is it now? Where is the Post Office? Days of the week. Months in a year. Use of Preposition zai, gen. Use of interrogative pronoun duoshao and ji. Whose??? Sweater etc is it? Different Games and going out for exercise in the morning. Module V The verb qu Going to the library issuing a book from the library Going to the cinema hall, buying tickets Going to the post office, buying stamps Going to the market to buy things.. etc Going to the buy clothes . Etc. Hobby. I also like swimming. Comprehension and answer questions based on it.
Examination Scheme:
Components Weightage (%) V 10 H 10 CT 20 EEI 60
Text & References:

Elementary Chinese Reader Part I Lesson 11-20
IMMUNOLOGY AND IMMUNOTECHNOLOGY

Course Code: MTBBT 20301 Course Objective:
Role of antibody engineering in biomedical applications and the importance of immuno genetics in disease processes, tissue transplantation and immune regulation are some of the areas of attributes of this course which can help the students to understand the biotechnology related to human kind.
Credit Units: 04
Course Content
Module I Phylogeny of Immune System, Types of immunity clonal nature of immune response. Organization and structure of lymphoid organs. Antibody structure and function. Major histocompatibilty: Complex BCR and TCR, generation of antibody diversity, Complement system Module II Cells of the immune system: hematopoiesis and differentiation, antigen processing and presentation, activation of B and T lymphocytes, cytokines and their role in immune regulation, T cell regulation and MHC restriction,immunological tolerance. Module III Cell mediated toxicity, Hypersensitivity, Autoimmunity, Vaccines: General considerations, ideotype network hypothesis Module IV Tumor immunology, Transplantation immunology, Immunotheropy. Module V Immuno diffusion, immuno-electrophoresis, ELISA, RIA, fluorescence activated cell sorter, (FACS) Hybridoma technology and its application
Examination Scheme:
Text & References:

Text: Immunology by J. Kubey Fence Creek Publishing (Blackwell). Immunology by Ivan Riott References: Basic Immunology, A.K. Abbas and A.H. Lichtman, Saunders W.B. Company Fundamentals of Immunology, W. Paul, Lippincott Williams and Wilkins Immunology, W.L. Anderson, Fence Creek Publishing (Blackwell). Immunology: A Short Course, E. Benjamin, R. Coico and G. Sunshine, Wiley-Leiss Inc. Immunology, Roitt, Mosby Yearbook Inc.
ENZYMOLOGY AND ENZYME TECHNOLOGY

The course aims to provide an understanding of the principles and application of proteins, secondary metabolites and enzyme biochemistry in therapeutic applications and clinical diagnosis. The theoretical understanding of biochemical systems would certainly help to interpret the results of laboratory experiments.
MTBBT 20302
Credit Units: 04
Course Contents:
Module I Enzymes: General characteristics of enzymes, Mechanism of action of few enzymes: lysozyme, ribozymes, chymotrypsin and alcohol dehydrogenase. Module II Enzyme Kinetics: Single substrate steady state kinetics; Multisubstrate systems , Enzyme Inhibitors as therapeutic agents, active site, Isozyme and multienzyme complex . Module III Applications of enzymes: clinical and Industrial, Enzyme Immobilization and its applications. Module IV Enzyme Reactors: reactors for batch/continuous enzymatic processing, Choice of reactor type: idealized enzyme reactor systems; Mass Transfer in Enzyme Reactors: Steady state analysis of mass transfer and biochemical reaction in enzyme reactors. Module V Bio-process Design: Physical parameters, reactor operational stability; Immobilized cells. Module VI Challenges and future trends: Catalytic antibodies, Thermostable enzymes with special references to amylases, lipases and proteases.
Examination Scheme:
Text & References:

Text: Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady State Enzyme Systems by I.H. Segel, Wiley-Interscience Enzyme Technology by M.F. Chaplin and C. Bucke, Cambridge University Press. References: Biotechnological Innovations in Chemical Synthesis by R.C.B. Currell, V.D. Mieras, Biotol Partners Staff, Butterworth Heinemann. Enzymes: A Practical Introduction to Structure, Mechanism and Data Analysis by R.A. Copeland, John Wiley and Sons Inc. Enzymes Biochemistry, Biotechnology, Clinical Chemistry by Trevor Palmer Industrial Enzymes & their applications by H. Uhlig, John Wiley and Sons Inc.
DRUG DESIGN AND DEVELOPMENT

The aim of the course is to identify and design drugs that could be potentially useful in the identification of the candidate drugs, which have efficacy in cell culture or animal models, and thus the most effective compounds could be employed based on the above results for being moved through preclinical studies to clinical trials.
MTBBT 20303
Credit Units: 04
Course Contents:
Module I Drug targets classification: DNA, RNA, Protein modifications/events, post-translational, processing enzymes, G protein coupled receptors (monomeric transmembrane proteins), small molecule receptors, neuropeptide receptors, ion channels (monomeric multi-transmembrane) proteins, ligand-gated ion channels (oligomeric transmembrane proteins), transporters (multi-transmembrane proteins). Module II Introduction to drug discovery and development, target discovery and validation strategies: Genomics (new target discovery), biological activity directed and other types of screening, natural products, combinatorial chemistry. Pharmacakinetics and Tonicological considerasation. Module III Computer Aided drug design, Structure-based design: de novo design methodologies: docking. Module IV Design and development of combinatorial libraries for new lead generation: The molecular diversity problem, drug characterization principles of equilibria, diffusion and kinetics, preformulation: pKa, partition coefficient, solubility, dissolution, chemical stability, and permeability, optimization of ADME characteristics, physicochemical properties calculation, Linear Free energy, Hanseh equation, Hammett euation, chemiometrics in drug design. Module V QSAR:Statistical techniques behind QSAR, classical QSAR, molecular descriptors 3D QSAR and COMFA, drug design to discovery and development
Examination Scheme:
Text & References:

Text: Introduction to Biophysical Methods for Protein and Nucleic Acid Research by J.A. Glasel and M.P. Deutscher, Academic Press Principles of Drug Action by W.B. Pratt and P. Taylor, Churchill Livingston. References: Principles of Medicinal Chemistry by W.O. Foye, T.L. Lemke, and D.A. Williams, Williams and Wilkins. Side Effects and Drug Desig by E.J. Lien, Marcel Dekker The Anticancer Drugs by W.B. Pratt, R.W. Ruddon, W.D. Ensminger, and J. Maybaum, Oxford University Press.
POLLUTION PREVENTION FUNDAMENTALS

To develop an understanding of the methods and impacts of waste minimization including waste pollution prevention and recycling, obtain an overview of relevant environmental laws and regulations governing waste management, understand the phenomena and environmental impact of green-house gases and alternative energy sources to reduce the effect of global warming.
MTBBT 20304
Credit Units: 04
Course Contents:
Module I Pollution Prevention In Industries: Environment friendly chemical processes-Properties and fates of environmental contaminants- Regulations for clean environment and implications for industries Improved Manufacturing Operations. Module II Life Cycle Assessment and Environmental Audit: Life cycle assessment and pollution prevention economicsHazard and risk Analysis - Pollution prevention planning - Design for the environment. Module III Conservation Of Materials And Energy: Water energy and reagent conservation Residuals management Economic Recovery and Recycling of Wastes - Case studies. Module IV Total Quality Environment Management and Ems 14000: Municipal pollution prevention programmes Environment Management System-14000- Systematic, Structured and Documented Response to Environmental Issues- Auditable and Time Targeted Environmental Improvement Programs. Module V Hierarchy Of Environment Management Practices: Waste-specific pollution prevention: waste pre - generation focus on minimization / recycling, Waste-specific pollution control treatment: pre generation focus on disposal/ recycling- Waste-specific Post-release-to environment focus: recycling/ remediation
Examination Scheme:
Text & References:

Text: Pollution Prevention: Fundamentals and Practice by Bishop P., McGraw-Hill International Edition, McGraw-Hill book Co, Singapore Green Chemistry: Theory and Practice by P.T.Anastas and J.C. Warner,, Oxford UniversityPress. N.Y. References: Chemical Technology for better Environment by T.K. Roy, (Editor), Allied publishers Ltd, Chennai Pollution Prevention through Process Integration: Systematic Design Tools by El Halwagy, M.M, Academic Press, N.Y.
DRUG DELIVERY SYSTEMS

The course is to help the students in developing a detailed understanding of drug delivery system. After the completion of this course, the students are expected to be completely familiar with the different drug related aspects of a living body.
Credit Units: 04
Course Contents:
Module I Basic concepts of Drug Delivery: Introductory lecture , Concepts of Bio availability, Process of drug absorption, Pharmacokinetic processes, Timing for optimal therapy, Drug delivery considerations for the new biotherapeutics. Module II Advanced Drug Delivery and Targeting: Basic terminologies in drug delivery and drug targeting, Drug release, Drug targeting, Doses forms, Various routes of administration of drugs (just introduction), Strategies for enhanced therapeutic efficacies (Basic principles). Module III Drug administration: Parenteral delivery- intravenous, inrtamuscular, interperetoneal. Oral delivery and systemic delivery through oral route- structure and physiology of Gastro Intestinal tract, impediments against oral availability, advantages and disadvantages of oral drug delivery. Current technologies and new and emerging technologies in oral delivery. Nasal and pulmonary delivery, Ophthalmic delivery structure and physiology of eye, topical and intraocular drug delivery, Drug targeting to CNS- Blood- Brain barrier, physiological and physiochemical factors for delivering to CNS, current and new technologies in CNS delivery. Module IV Delivery of Genetic material:Basic principles of gene expression, Viral and nonviral vectors in gene delivery, Clinical applications of gene therapy and antisense therapy. Module V New generation technologies in Drug delivery and targeting: Nanotechnology / Nanobiotechnology, Use of biosensors and challenge of chronopharmacology, Microchips and controlled drug delivery, genetically engineered cell implants in drug delivery.
Examination Scheme:
Text & References:

Text: Drug Delivery and Targeting by A.M. Hillery, A.W. Lloyd and J. Swarbrick, Harwood Academic Publisher. Drug Delivery: Engineering Principles for Drug Therapy (Topics in Chemical Engineering), by W.M. Saltzman, Oxford University Press. References: Handbook of Biodegradable Polymers (Drug Targeting and Delivery), by A.J. Domb, J. Kost and D.M. Wiseman, Dunitz Martin Ltd. Pharmaceutical Dosage Forms and Drug Delivery System by H.C. Ansel, L.V. Allen and N.G. Popovich, Lippincott Williams and Wilkins Publisher.
BIO-ENERGY ENGINEERING
The goal is to introduce students to biotechnology and tools that enable engineers and process scientists to connect innovations in industrial microorganisms and bioprocess unit operations to the engineering fundamentals, fundamentals of systems biology, and biological tools for design, modeling and evaluation of manufacturing facilities for the production of biofuels, bioproducts and biotherapeutics using a case study approach combined with computer modeling.
Credit Units: 04
Course Contents:
Module I Biomass Sources, Characteristics & Preparation: Biomass Sources and Classification. Chemical composition and properties of different biomass materials and bio-fuels Sugar cane molasses and other sources for fermentation ethanol-Sources and processing of oils and fats for liquid fuels- Energy plantations -Preparation of woody biomass: Size reduction, Briquetting of loose biomass, Drying, Storage and Handling of Biomass. Module II Biogas, Technology: Feedstock for biogas production, Aqueous wastes containing biodegradable organic matter, animal residues-. Microbial and biochemical aspects- Operating parameters for biogas production Kinetics and mechanism - Dry and wet fermentation. Digesters for rural application-High rate digesters for industrial waste water treatment. Module III Bio-Ethanol and Bio-Diesel Technology: Production of Fuel Ethanol By Fermentation Of Sugars. Gasohol as a Substitute for Leaded Petrol. - Trans-Esterification of Oils to Produce Bio-Diesel. Module IV Pyrolysis and Gasification of Biomass: Thermo-chemical conversion of ligno-cellulose biomass - Biomass processing for liquid fuel production - Pyrolysis of biomass-Pyrolysis regime, effect of particle size, temperature, and products obtained. Thermo-chemical gasification principles: Effect of pressure, temperature and of introducing steam and oxygen. Design and operation of Fixed and Fluidized Bed Gasifiers. Module V Combustion Of Biomass And Cogeneration Systems: Combustion Of Woody Biomass: Theory, Calculations And Design Of Equipments. Cogeneration In Biomass Processing Industries. Case Studies: Combustion of Rice Husk, Use of Bagasse for Cogeneration.
Examination Scheme:
Text & References:

Text: Fuels from Biomass and Wastes by D.L. Klass and G.M. Emert, Ann Arbor Science pub. Inc. Michigan, Biotechnology and Alternative Technologies for Utilization of Biomass or Agricultural Wastes by A. Chakraverthy, Oxford & IBH publishing Co., New Delhi,
References: Biogas Systems: Principles and Applications by K.M.Mital, New Age International Publishers (p) Ltd., Biomass Energy Systems,by P.Venkata Ramana and S.N.Srinivas,Tata Energy Research Institute, New Delhi, 1996. Bio-gas Technology by Khandelwal K.C. and Mahdi, Tata McGraw-Hill pub. Co. Ltd., New Delhi Advances in bio-gas Technology by O.P. Chawla, I.C.A.R., New Delhi. 1970.
ADVANCED FOOD TECHNOLOGY

The purpose of the Food Technology major is to produce professionals with a wide range of pertinent knowledge and skills in food chemistry, food microbiology and safety, quantitative skills, engineering and processing, marketing and consumer research
MTBBT 20307
Credit Units: 04
Course Contents:
Module I Processing and preservation technologies used in the food industry: heating, drying and baking, irradiation (infrared, microwave and radio frequency), concentration, freezing, chemical preservation, chilling, fermentation, a combination of those technologies Module II Micro-organisms and their metabolites for food, feed and fuel, development and application of food enzymes : fungal amylases, alpha-amylase, pectinase, amyloglucosidase and catalase. Technology for improvement of the quality of fruit juice through enzymatic treatment, Food spoilage and food poisoning micro-organisms Module III Pre- and post-harvest technologies for extension of storage life and better handling and transportation of fresh fruits and vegetables, to sustain freshness and reduce spoilage Module IV Development of environment-friendly packaging materials based on product characteristics and performance properties of packaging materials, and finished package forms, process schedules for thermal processing of foods in cans, glass, tin-free steel and aluminium containers, and retortable pouches based on heat penetration studies and sterilization value Module V Food Safety in food service Establishment and other food areas
Examination Scheme:
Text & References:

Text: Food Technology by Fraziar Food Microbiology, 2nd edition by Adams and Moss. References: Evaluation Of Certain Food Additives And Contaminants, (WHO Technical Report Series 901) World Health Organization, Avenue Appia 20, 1211 Geneva 27, Switzerland International Journal of Food Science & Technology, Blackwell synergy publication Bioterrorism and Food Safety by Rasco and Bledsoe.
INDUSTRIAL SAFETY AND MANAGEMENT

Course addresses management and engineering design concepts required for process safety in chemical and biotechnology systems, with pharmaceutical manufacturing applications. Content focuses on sound engineering principles and practices as they apply to industrial situations, project design, risk mitigation, process and equipment integrity, and engineering codes and standards.
Credit Units: 04
Course Contents:
Module I Hazards: Chemical hazards classification. Radiation hazards and control of exposure to radiation. Types of fire and fire prevention methods. Mechanical hazards. Electrical hazards Module II Psychology and Hygiene: Industrial psychology Industrial hygiene. Safety in plant site selection and plant layout. Industrial lighting and ventilation. Industrial noise. Module III Occupational diseases and control: Occupational diseases and prevention methods. Safe housekeeping, Instrumentation for safe operation. Personal protective equipments. Safety in chemical operations and processes. Module IV Management: Safety organization safety committee safety education and training. Management process. Philosophy and need for Industrial safety. Role of Government in Industrial safety. Module V Laws: Factory Act. ESI Act, Environmental Act. Workment - comperation Act. Advantages of adopting safety laws.
Examination Scheme:
Text & References:

Text: Guide for Safety in the Chemical laboratory second edition, Manufacturing Chemists Allocation. Van vostrand Reinhold Company, New York. Safety and Accident Prevention in Chemical Operation 2nd Edn., H.H.Fawcett & W.S .Wood Wiley Interscience, References: Industrial Safety and Laws by Indian School of Labour Education, Madras.
ADVANCED ANIMAL AND PLANT CELL TECHNOLOGY

The application of Plant Biotechnology covers major areas related to commercial applications. Regeneration of plants through in vitro techniques offers a practical strategy for micro propagation. Importance will also be given to areas like in vitro fertilization, animal cell and tissue culture, hormone vaccine and important enzyme production through animal biotechnology.
MTBBT 20309
Credit Units: 04
Course Contents :
ADVANCED ANIMAL CELL TECHNOLOGY Module I Brief history of animal cell and organ culture,Cultivation of animal cell en masse in bioreactor, methods for scale-up, immobilized cell culture, insect cell culture, somatic cell culture, organ culture, and embryo culture. Module II Valuable products from cell culture, Production of recombinant tissue-plasminogen-activator, blood factor VIII, erythropoietin, insulin, somatostatin, somatotropin. Module III Hybridoma technology, Monoclonal antibodies- production and application, Stem cell technology, custom made animals and tissue engineering ADVANCED PLANT CELL TECHNOLOGY Module IV Brief introduction to various tissue culture techniques, Cell Cultures, regeneration and preservation: Plant regeneration through meristem, callus (somatic embryogenesis) and anthers. Protoplast culture and somatic hybridization. Production, preservation and use of somatic embryos. Artificial Seeds and Cybrids. Module V Induction & utilization of somatic variants; Secondary metabolite production through cell cultures. Principles and the technology, pharmaceutical, secondary metabolites & beverage production; Commercialization of tissue culture technology (Micropropagation). Plant cell reactors. Immobilized plant cell reactors Module VI Engineering of Chloroplast and mitochondrial genomes and their applications, Biotransformation by plant cells.
Examination Scheme:
Text & References:

Text: Plant Biotechnology, J. Hammond, P.McGarvy and V. Yusibov, Springer Verlag. Experiments in Plant Tissue Culture, J.H. Dodds and L.K. Roberts, Cambridge University Press Culture of Animal Cells, R.I Freshney, Wiley-Leiss References: An Introduction to Plant Tissue Culture, M.K. Razdan, Oxford and IBH Publishing Plant Biotechnology and Transgenic Plants, K.M.O. Caldenty, W.H. Barz and H.L. Wills, Marcel Dekker Plant Cell & Tissue Culture for the Production of Food Ingredients, T-J Fu, G. Singh and W.R. Curtis, Kluwer Adacemic/Plenum Press Plant Tissue Culture: Theory & Practice, S.S. Bhojwani and M.K. Razdan, Elsevier Health Sciences Animal Cell Culture Techniques, M. Clynes, Springer Verlag Cell Culture LabFAx, M. Butler and M. Dawson, Bios scientific Publications Ltd. Cell Growth and Division A Practical approach, R. Basega, IRL Press Comprehensive Biotechnology, Moo-Young, Alan T. Bullm Howard Dalton, Panima Publication
IMMUNOLOGY AND IMMUNOTECHNOLOGY LAB

Course Code: MTBPL 20321 Credit Units: 03
Course Objective: The objectives of the course is to understand the principles of immune function and immunization and to provide advanced training in modern cellular and molecular immunology, with emphasis on the interface between the basic and clinical aspects of the subject. Course Contents:
Module I Blood film preparation and identification of cells, Identification of blood group, Isolation of serum. Module II Lymphoid organs and their microscopic organization. Module III WIDAL Test, Radial Immuno Diffusion Test, Ouchterlony Double diffusion Test, ELISA:- DOT, SANDWICH Module IV Purification of IgG through affinity chromatography Module V Immunohistochemistry
Examination Scheme:
ENZYMOLOGY AND ENZYME TECHNOLOGY LAB

To integrate the practical aspects of enzymology with the kinetic theories to provide a mechanistic overview of enzyme activity and regulation in cells
MTBPL 20322
Credit Units: 03
Course Contents:
Module I Isolation of Enzymes from plant and microbial sources. Module II Enzyme assay; activity and specific activity determination of amylase, acid phosphatase, cellulase, protease. Module III Production of enzyme on industrial scale using solid and liquid-state fermentation. Module IV Purification of enzyme by ammonium sulphate fractionation, ion-exchange, gel permeation chromatography. Module V Enzyme Kinetics: Determination of Michaelis-Menten constant (Km) and Maximum Velocity (Vmax), Temperature optima and pH optima of an enzyme. Module VI Enzyme immobilization and its effect on enzyme activity
Examination Scheme:
TERM PAPER - III

1. 2. 3. 4. 5. Choosing a subject Finding sources of materials Collecting the notes Outlining the paper Writing the first draft 6. Editing & preparing the final paper

g) The material sources should be not more than 10 years old unless the nature of the paper is such that it involves examining older writings from a historical point of view. h) Begin by making a list of subject-headings under which you might expect the subject to be listed. i) The sources could be books and magazine articles, news stories, periodicals, scientific journals etc.

Skim through sources, locating the useful material, then make good notes of it, including quotes and information for footnotes. g) Get facts, not just opinions. Compare the facts with author's conclusion. h) In research studies, notice the methods and procedures, results & conclusions. i) Check cross references.

e) f) Review notes to find main sub-divisions of the subject. Sort the collected material again under each main division to find sub-sections for outline so that it begins to look more coherent and takes on a definite structure. If it does not, try going back and sorting again for main divisions, to see if another general pattern is possible.


m) Before writing a term paper, you should ensure you have a question which you attempt to answer in your paper. This question should be kept in mind throughout the paper. Include only information/ details/ analyses of relevance to the question at hand. Sometimes, the relevance of a particular section may be clear to you but not to your readers. To avoid this, ensure you briefly explain the relevance of every section. n) Read the paper to ensure that the language is not awkward, and that it "flows" properly. o) Check for proper spelling, phrasing and sentence construction. p) Check for proper form on footnotes, quotes, and punctuation. q) Check to see that quotations serve one of the following purposes: (vii) Show evidence of what an author has said. (viii) Avoid misrepresentation through restatement. (ix) Save unnecessary writing when ideas have been well expressed by the original author. r) Check for proper form on tables and graphs. Be certain that any table or graph is self-explanatory.
Discussion
Conclusion
The conclusion is often thought of as the easiest part of the paper but should by no means be disregarded. There are a number of key components which should not be omitted. These include: i) summary of question posed j) summary of findings k) summary of main limitations of the study at hand l) details of possibilities for related future research
References:
Conventions:
Edited volumes
Edited articles
Journal articles:
Electronic book:

Other websites:
Unpublished papers:
Unpublished thesis/ dissertations:

Appendix
Assessment Scheme:
60%
COMMUNICATION SKILLS - III

To initiate the learners with the basic mechanics of writing skills and facilitate them with the core skills required for communication in the professional world.
MTBBS 20301
Credit Units: 01
Course Contents:
Module I: Mechanics and Semantics of Sentences Writing effective sentences Style and Structure Module II: Developing writing skills Inter - office communication: Business Letter; E mails; Netiquette Intra office communication: Memos, Notices, Circulars, Minutes Report Writing Module III: Business Presentations Planning, design and layout of presentation Information Packaging Audience analysis Audio visual aids Speaking with confidence Case Studies
Examination Scheme:
Text & References:

Krishnaswamy, N, Creative English for Communication, Macmillan Raman Prakash, Business Communication, Oxford.
BEHAVIOURAL SCIENCE - III (LEADING THROUGH TEAMS)

This course aims to enable students to: Understand the concept and building of teams Manage conflict and stress within team Facilitate better team management and organizational effectiveness through universal human values.
MTBBS 20302
Credit Units: 01
Course Contents:
Module I: Teams: An Overview Team Design Features: team vs. group Effective Team Mission and Vision Life Cycle of a Project Team Rationale of a Team, Goal Analysis and Team Roles Module II: Team & Sociometry Patterns of Interaction in a Team Sociometry: Method of studying attractions and repulsions in groups Construction of sociogram for studying interpersonal relations in a Team Module III: Team Building Types and Development of Team Building Stages of team growth Team performance curve Profiling your Team: Internal & External Dynamics Team Strategies for organizational vision Team communication Module IV: Team Leadership & Conflict Management Leadership styles in organizations Self Authorized team leadership Causes of team conflict Conflict management strategies Stress and Coping in teams Module V: Global Teams and Universal Values Management by values Pragmatic spirituality in life and organization Building global teams through universal human values Learning based on project work on Scriptures like Ramayana, Mahabharata, Gita etc. Module VI: End-of-Semester Appraisal Viva based on personal journal Assessment of Behavioral change as a result of training Exit Level Rating by Self and Observer
Text & References:

Organizational Behaviour, Davis, K. Hoover, Judhith D. Effective Small Group and Team Communication, 2002,Harcourt College Publishers LaFasto and Larson: When Teams Work Best, 2001, Response Books (Sage), New Delhi Dick, Mc Cann & Margerison, Charles: Team Management, 1992 Edition, viva books J William Pfeiffer (ed.) Theories and Models in Applied Behavioural Science, Vol 2, Group (1996); Pfeiffer & Company Smither Robert D.; The Psychology of Work and Human Performance, 1994, Harper Collins College Publishers
FRENCH - III
To provide the students with the know-how To master the current social communication skills in oral and in written. To enrich the formulations, the linguistic tools and vary the sentence construction without repetition.
MTBFR 20301
Credit Units: 02
Course Contents:
Module B: pp. 76 88 Unit 6 Module C: pp. 89 to103 Unit 7 Contenu lexical: Unit 6 : se faire plaisir 1. acheter : exprimer ses choix, dcrire un objet (forme, dimension, poids et matires) payer 2. parler de la nourriture, deux faons dexprimer la quantit, commander un repas au restaurant 3. parler des diffrentes occasions de faire la fte Unit 7 : Cultiver ses relations 1. matriser les actes de la communication sociale courante (Salutations, prsentations, invitations, remerciements) 2. annoncer un vnement, exprimer un souhait, remercier, sexcuser par crit. 3. caractriser une personne (aspect physique et caractre) Contenu grammatical : 1. accord des adjectifs qualificatifs 2. articles partitifs 3. Ngations avec de, nerien/personne/plus 4. Questions avec combien, quel 5. expressions de la quantit 6. neplus/toujours - encore 7. pronoms complments directs et indirects 8. accord du participe pass (auxiliaire avoir ) avec lobjet direct 9. Impratif avec un pronom complment direct ou indirect 10. construction avec que - Je crois que/ Je pense que/ Je sais que
Examination Scheme:
Text & References:

GERMAN - III
To enable the students to converse, read and write in the language with the help of the basic rules of grammar, which will later help them to strengthen their language. To give the students an insight into the culture, geography, political situation and economic opportunities available in Germany
MTBGR 20301
Credit Units: 02
Course Contents:
Module I: Modal verbs Modal verbs with conjugations and usage Imparting the finer nuances of the language Module II: Information about Germany (ongoing) Information about Germany in the form of presentations or Referat neighbors, states and capitals, important cities and towns and characteristic features of the same, and also a few other topics related to Germany. Module III: Dative case Dative case, comparison with accusative case Dative case with the relevant articles Introduction to 3 different kinds of sentences nominative, accusative and dative Module IV: Dative personal pronouns Nominative, accusative and dative pronouns in comparison Module V: Dative prepositions Dative preposition with their usage both theoretical and figurative use Module VI: Dialogues In the Restaurant, At the Tourist Information Office, A tlelphone conversation Module VII: Directions Names of the directions Asking and telling the directions with the help of a roadmap Module VIII: Conjunctions To assimilate the knowledge of the conjunctions learnt indirectly so far
Examination Scheme:
Text & References:

SPANISH III
To enable students acquire knowledge of the Set/definite expressions (idiomatic expressions) in Spanish language and to handle some Spanish situations with ease.
MTBSH 20301
Credit Units: 02
Course Contents:
Module I Revision of earlier semester modules Set expressions (idiomatic expressions) with the verb Tener, Poner, Ir. Weather Module II Introduction to Gustarand all its forms. Revision of Gustar and usage of it Module III Translation of Spanish-English; English-Spanish. Practice sentences. How to ask for directions (using estar) Introduction to IR + A + INFINITIVE FORM OF A VERB Module IV Simple conversation with help of texts and vocabulary En el restaurante En el instituto En el aeropuerto Module V Reflexives
Examination Scheme:
Text & References:

Espaol, En Directo I A Espaol Sin Fronteras -Nivel Elemental
JAPANESE - III
To enable the students to converse in the language with the help of basic verbs and to express themselves effectively and narrate their everyday short encounters. Students are also given projects on Japan and Japanese culture to widen their horizon further. Note: The Japanese script is introduced in this semester.
MTBJP 20301
Credit Units: 02
Course Contents:
Module I: Verbs Different forms of verbs: present continuos verbs etc Module II More Adverbs and adverbial expressions Module III: Counters Learning to count different shaped objects, Module IV: Tenses Past tense, Past continuous tense. Module V: Comparison Comparative and Superlative degree Module VI: Wishes and desires Expressing desire to buy, hold, possess. Usage in negative sentences as well. Comparative degree, Superlative degree. Module VII: Appointment Over phone, formal and informal etc.
Learning Outcome
Students can speak the language and can describe themselves and situations effectively They also gain great knowledge in terms of Japanese lifestyle and culture, which help them at the time of placements.

Handouts, audio-aids, and self-do assignments. Use of library, visiting and watching movies in Japan and culture center every Friday at 6pm.
Examination Scheme:
Text & References:

CHINESE III
Foreign words are usually imported by translating the concept into Chinese, the emphasis is on the meaning rather than the sound. But the system runs into a problem because the underlying name of personal name is often obscure so they are almost always transcribed according to their pronciation alone. The course aims at familiarizing the student with the basic aspects of speaking ability of Mandarin, the language of Mainland China. The course aims at training students in practical skills and nurturing them to interact with a Chinese person.
MTBCE 20301
Credit Units: 02
Course Contents:
Module I Drills Dialogue practice Observe picture and answer the question. Introduction of written characters. Practice reading aloud Practice using the language both by speaking and by taking notes. Character writing and stroke order Module II Measure words Position words e.g. inside, outside, middle, in front, behind, top, bottom, side, left, right, straight. Directional words beibian, xibian, nanbian, dongbian, zhongjian. Our school and its different building locations. What game do you like? Difference between hii and neng, keyi. Module III Changing affirmative sentences to negative ones and vice versa Human body parts. Not feeling well words e.g. ; fever, cold, stomach ache, head ache. Use of the modal particle le Making a telephone call Use of jiu and cal (Grammar portion) Automobiles e.g. Bus, train, boat, car, bike etc. Traveling, by train, by airplane, by bus, on the bike, by boat.. etc. Module IV The ordinal number di Mei the demonstrative pronoun e.g. mei tian, mei nian etc. use of to enter to exit Structural particle de (Compliment of degree). Going to the Park. Description about class schedule during a week in school. Grammar use of li and cong. Comprehension reading followed by questions. Module V Persuasion-Please dont smoke. Please speak slowly Praise This pictorial is very beautiful Opposites e.g. Clean-Dirty, Little-More, Old-New, Young-Old, Easy-Difficult, Boy-Girl, Black-White, BigSmall, Slow-Fast etc. Talking about studies and classmates Use of it doesnt matter Enquiring about a student, description about study method. Grammar: Negation of a sentence with a verbal predicate.
Examination Scheme:
Text & References:

Elementary Chinese Reader Part I, Part-2 Lesson 21-30
SUMMER PROJECT
Course Code: MTBPR 20370 Credit Units: 09
GUIDELINES FOR PROJECT FILE

Research experience is as close to a professional problem-solving activity as anything in the curriculum. It provides exposure to research methodology and an opportunity to work closely with a faculty guide. It usually requires the use of advanced concepts, a variety of experimental techniques, and state-of-the-art instrumentation. Research is genuine exploration of the unknown that leads to new knowledge which often warrants publication. But whether or not the results of a research project are publishable, the project should be communicated in the form of a research report written by the student. Sufficient time should be allowed for satisfactory completion of reports, taking into account that initial drafts should be critiqued by the faculty guide and corrected by the student at each stage. The File is the principal means by which the work carried out will be assessed and therefore great care should be taken in its preparation.
In general, the File should be comprehensive and include:

A short account of the activities that were undertaken as part of the project; A statement about the extent to which the project has achieved its stated goals. A statement about the outcomes of the evaluation and dissemination processes engaged in as part of the project; Any activities planned but not yet completed as part of the project, or as a future initiative directly resulting from the project; Any problems that have arisen that may be useful to document for future reference.
Report Layout
The report should contain the following components: Title or Cover Page. The title page should contain the following information: Project Title; Students Name; Course; Year; Supervisors Name.
Acknowledgements (optional)
Acknowledgment to any advisory or financial assistance received in the course of work may be given.
Abstract
A good "Abstract" should be straight to the point; not too descriptive but fully informative. First paragraph should state what was accomplished with regard to the objectives. The abstract does not have to be an entire summary of the project, but rather a concise summary of the scope and results of the project
Table of Contents
Titles and subtitles are to correspond exactly with those in the text.
Introduction
Here a brief introduction to the problem that is central to the project and an outline of the structure of the rest of the report should be provided. The introduction should aim to catch the imagination of the reader, so excessive details should be avoided.
Materials and Methods

This section should aim at experimental designs, materials used. Methodology should be mentioned in details including modifications if any.
Results and Discussion

Present results, discuss and compare these with those from other workers, etc. In writing these section, emphasis should be given on what has been performed and achieved in the course of the work, rather than discuss in detail what is readily available in text books. Avoid abrupt changes in contents from section to section and maintain a lucid flow throughout the thesis. An opening and closing paragraph in every chapter could be included to aid in smooth flow.
Note that in writing the various secions, all figures and tables should as far as possible be next to the associated text, in the same orientation as the main text, numbered, and given appropriate titles or captions. All major equations should also be numbered and unless it is really necessary never write in point form.
Conclusion
A conclusion should be the final section in which the outcome of the work is mentioned briefly.
Future prospects Appendices

The Appendix contains material which is of interest to the reader but not an integral part of the thesis and any problem that have arisen that may be useful to document for future reference.
References
This should include papers and books referred to in the body of the report. These should be ordered alphabetically on the author's surname. The titles of journals preferably should not be abbreviated; if they are, abbreviations must comply with an internationally recognised system. Examples: For research article: Voravuthikunchai SP, Lortheeranuwat A, Ninrprom T, Popaya W, Pongpaichit S, Supawita T. (2002) Antibacterial activity of Thai medicinal plants against enterohaemorrhagic Escherichia coli O157: H7. Clin Microbiol Infect , 8 (suppl 1): 116117. For book: Kowalski,M.(1976) Transduction of effectiveness in Rhizobium meliloti. SYMBIOTIC NITROGEN FIXATION PLANTS (editor P.S. Nutman IBP), 7: 63-67
ASSESSMENT OF THE PROJECT FILE

Essentially, marking will be based on the following criteria: the quality of the report, the technical merit of the project and the project execution. Technical merit attempts to assess the quality and depth of the intellectual efforts put into the project. Project execution is concerned with assessing how much work has been put in. The File should fulfill the following assessment objectives:
Range of Research Methods used to obtain information Execution of Research Data Analysis
Analyse Quantitative/ Qualitative information Control Quality
Draw Conclusions Examination Scheme:

Dissertation: Viva Voce: Total: 50 50 100
GENOMICS AND PROTEOMICS

Course Code: MTBBT 20401 Credit Units: 04
Course Objective: The course helps in developing a detailed understanding of eukaryotic genome complexity and organization. Current research on the molecular basis of the control of gene expression in eukaryotic has developed a detailed understanding of techniques of gene diagnostics and DNA profile to acquire the fundamental of genomics and bioinformatics, it is desirable to have in depth study on these lines. Course Contents:
GENOMICS Module I Introduction to Genomics: Anatomy of prokaryotic and eukaryotic genome. Contents of genomes, Repetitive DNA. Bioinformatics for the analysis of sequence data. Module II Transcriptomes: Genome expression; RNA Contents, genetic mapping, Microsatellite DNA markers, RFLP, DNA sequencing, PCR, Micro array: DNA micro array marker, random primers, computational methods. Module III Strategies for large-scale sequencing projects. The structure, function and evolution of the human genome. The human genome project. Human disease genes. PROTEOMICS Module IV Introduction to proteomics. Protein structure: secondary structural elements, super-secondary structure, domains, mechanisms of protein folding, tertiary folds. Formation of oligomers. Protein solubility and interaction with solvents and solutes. The activity of proteins. Protein engineering principles. Module V Fundamental methods used in proteomics, Relationship between protein structure and function. Post translational protein modifications. Protein protein interaction. Module VI Use of computer simulations and knowledge-based methods in the design process. De-novo design; making use of databases of sequence and structure.
Examination Scheme:
Text & References:

Text: Genomes II, T.A. Brown Recombinant DNA (Second Edition), James D. Watson and Mark Zoller References: A Primer of Genome Science, Greg Gibson and Spencer V. Muse Database Annotation in Molecular Biology: Principles and Practice, Arthur M. Lesk Gene Cloning and DNA Analysis An introduction (Fourth Edition), T.A. Brown Genes & Genomes, Maxine Singer and Paul Berg DNA : Structure and Function, Richard R. Sinden www.panimaText.com
PHARMACEUTICAL TECHNOLOGY
The main objectives are to cover representative pharmaceutical dosage forms, and general issues of formulation, production, quality requirements, validation and uses and to gain an understanding of the challenges associated with quality pharmaceutical manufacturing
MTBBT 20402
Credit Units: 04
Course Contents:
Module I Introduction to Physical Pharmaceutics - Metrology and Calculations, Module II Molecular structure, properties and States of Matter, Solutions, Phase Equilibra, Micromeritic and Powder Rheology, Surface and Interfacial Phenomena, Dispersion Systems, Diffusion & Dissolution, Kinetics and drug stability, Viscosity & Rheology Module III Polymer Science and Applications, Formulations and Development, Packaging Module IV Introduction to Industrial Processing, Transport Phenomena (Fluid Flow, Heat Transfer and Mass Transfer) Module V Particulate Technology (Particle Size, Size reduction, Size Separation, Powder Flow and Compaction), Unit Operations (Mixing, Evaporation, Filtration, Centrifugation, Extraction, Distillation, and Drying) Module VI Materials of Pharmaceutical Plant Construction, Good Manufacturing Practice (GMPs) Guidelines
Examination Scheme:
Text & References:

Text: Bentley's Pharmaceutics by E A Rawlins Pharmaceutical Sciences by Remington References: Physical Pharmacy by Alfred Martin. Cooper and Gunn's Tutorial Pharmacy
BIOPROCESS PLANT DESIGN

The objective of this paper is to include the application of chemical engineering principles/unit operations to bioprocess systems and the principles of disciplines of mechanical, electrical and industrial engineering to design a completely economically optimal process using living or subcomponent of cells.
MTBBT 20403
Credit Units: 04
Course Contents:
Module I Introduction; general design information; Mass and energy balance. Module II Flow sheeting; Piping and instrumentation; Materials of construction for bioprocess plants; Mechanical design of process equipment. Module III Vessels for biotechnology application; Design of fermenters; Design considerations for maintaining sterility of process streams processing equipment. Module IV Selection and specification of equipment for handling fluids and solids; Selection, specification, design of heat and mass transfer equipment used in bioprocess industries. Module V Design of facilities for cleaning of process equipment used in biochemical industries. Module VI Utilities of biotechnology production plants; Process economics; Bioprocess validation; Safety considerations; Case studies.
Examination Scheme:
Text & References:

Text: Applied Process Design for Chemical and Petrochemical Plants by E.E. Ludwig, Butterworth-Heinemann. Chemical Engineering by R.K. Sinnott, J.M. Coulson and J.F. Richardson, Butterworth-Heinemann. References: Chemical Engineers Handbook by R.H. Perry and D.W. Green, McGraw-Hill Manufacturing Facilities Design and Material Handling by F.E. Meyers and M.P. Stephens, Prentice Hall Plant Design and Economics for Chemical Engineers by M. Peters and K. Timmerhaus, McGraw-Hill Process Plant Layout and Piping Design by E. Bausbacher and R. Hunt, Prentice Hall PTR.
GENOMICS AND PROTEOMICS LAB

The course will serve to introduce students to the materials and methods of DNA and protein analysis and the computational tools developed for genomics and proteomics in a variety of species
MTBPL 20421
Credit Units: 02
Course Contents:
Module I Three dimensional Structures In silico study large molecular complexes RNA polymerase II, ribosome, unstructured proteins Module II DNA sequencing methods, gene finding tools and Genome annotation Module III Comparison of two given genomes, Analysis of 2D IEF data Module IV Micro array and Micro array data analysis, Inference of protein function from structure Module V Two-hybrid methods
Examination Scheme:
COMMUNICATION SKILLS - IV
To facilitate the learner with Academic Language Proficiency and make them effective users of functional language to excel in their profession. TOTAL CREDIT UNITS: 01
MTBBS 20401
Credit Units: 01
Course Contents:
Module I: Introduction to Speaking Skills Business Conversation Effective Public Speaking Art of Persuasion Module II: Speaking for Employment Types of Interview Styles of Interview Facing Interviews-Fundamentals and Practice Session Conducting Interviews- Fundamentals and Practice Session Question Answer on Various Dimensions Module III: Basic Telephony Skills Guidelines for Making a Call Guidelines for Answering a Call Telephone Word Groups Answering Systems and Voice-Mail Module IV: Work Place Speaking Team Briefing Conflict Management Negotiations Participation in Meetings Keynote Speeches
Examination Scheme:
Text & References:

Jermy Comfort, Speaking Effectively, et.al, Cambridge Krishnaswamy, N, Creative English for Communication, Macmillan Raman Prakash, Business Communication, Oxford. Taylor, Conversation in Practice.
BEHAVIOURAL SCIENCE - IV (PERSONAL AND PROFESSIONAL EXCELLENCE)

This course aims at imparting an understanding of: Build and leverage your professional reputation Maintain focus in pressure situations Make a balanced choice between professional and personal commitments
MTBBS 20402
Credit Units: 01
Course Contents:
Module I: Individual, Society and Nation Individual Differences and Dimensions of Personality Socialization Process Relating to the Nation: Values, Culture, Religion Sense of pride and Patriotism Managing Diversity Module II: Components of Excellence Personal Excellence: Identifying long-term choices and goals Uncovering the talent, strength & style Analyzing choke points in your personal processes by analysis in area of placements, events, seminars, conference, extracurricular activities, projects etc. Developing professional power: Goal-setting, time management, handling criticism, interruptions and time wasters Module III: Career Planning Knowing ones Interest and Aptitude Identifying available Resources Setting goals to maintain focus: Developing Positive attributes in personality Self-reliance and Employability skills Module IV: Stress Management for Healthy Living Meaning and Nature of Stress Stages of stress Causes and Consequences of stress: Personal, Organizational and Environmental Personal Styles and strategies of coping Module V: Professional Success Building independence & interdependence Reducing resistance to change Continued reflection (Placements, events, seminars, conferences, projects extracurricular Activities etc.) Module VI: End-of-Semester Appraisal Viva based on personal journal Assessment of Behavioral change as a result of training Exit Level Rating by Self and Observer
Text & References:

J William Pfeiffer (ed.) Theories and Models in Applied Behavioural Science, Vol 2, Group (1996); Pfeiffer & Company Smither Robert D.; The Psychology of Work and Human Performance, 1994, Harper Collins College Publishers Raman, A.T. (2003) Knowledge Management: A Resource Book. Excel Books, Delhi. Kamalavijayan, D. (2005). Information and Knowledge Management. Macmillan India Ltd. Delhi
FRENCH - IV
To enable students: To develop strategies of comprehension of texts of different origin To present facts, projects, plans with precision
MTBFR 20401
Credit Units: 02
Course Contents:
Module C: pp. 104 139 : Units 8,9 Contenu lexical : Unit 8 : Dcouvrir le pass 1. parler du pass, des habitudes et des changements. 2. parler de la famille, raconter une suite dvnements/prciser leur date et leur dure. 3. connatre quelques moments de lhistoire Unit 9 : Entreprendre 1. faire un projet de la ralisation: (exprimer un besoin, prciser les tapes dune ralisation) 2. parler dune entreprise 3. parler du futur Contenu grammatical : 1. Imparfait 2. Pronom en 3. Futur 4. Discours rapport au prsent 5. Pass rcent 6. Prsent progressif
Examination Scheme:
Text & References:

GERMAN - IV
To enable the students to converse, read and write in the language with the help of the basic rules of grammar, which will later help them to strengthen their language. To give the students an insight into the culture, geography, political situation and economic opportunities available in Germany. Introduction to Advanced Grammar Language and Professional Jargon
MTBGR 20401
Credit Units: 02
Course Contents:
Module I: Present perfect tense Present perfect tense, usage and applicability Usage of this tense to indicate near past Universal applicability of this tense in German Module II: Letter writing To acquaint the students with the form of writing informal letters. Module III: Interchanging prepositions Usage of prepositions with both accusative and dative cases Usage of verbs fixed with prepositions Emphasizing on the action and position factor Module IV: Past tense Introduction to simple past tense Learning the verb forms in past tense Making a list of all verbs in the past tense and the participle forms Module V: Reading a Fairy Tale Comprehension and narration Rotkppchen Froschprinzessin Die Fremdsprache Module VI: Genitive case Genitive case Explain the concept of possession in genitive Mentioning the structure of weak nouns Module VII: Genitive prepositions Discuss the genitive propositions and their usage: (whrend, wegen, statt, trotz) Module VIII: Picture Description Firstly recognize the persons or things in the picture and identify the situation depicted in the picture; Secondly answer questions of general meaning in context to the picture and also talk about the personal experiences which come to your mind upon seeing the picture.
Examination Scheme:
Text & References:

SPANISH - IV
To enable students acquire working knowledge of the language; to give them vocabulary, grammar, voice modulations/intonations to handle everyday Spanish situations with ease.
MTBSH 20401
Credit Units: 02
Course Contents:
Module I Revision of earlier semester modules Introduction to Present Continuous Tense (Gerunds) Module II Translation with Present Continuous Tense Introduction to Gustar, Parecer, Apetecer, doler Module III Imperatives (positive and negative commands of regular verbs) Module IV Coomercial/business vocabulary Module VI Simple conversation with help of texts and vocabulary En la recepcion del hotel En el restaurante En la agencia de viajes En la tienda/supermercado
Examination Scheme:
Text & References:

Espaol Sin Fronteras (Nivel Elemental)
JAPANESE - IV
To enable the students to comfortably interact using basic Japanese. Note: Teaching is done in roman as well as Japanese script, students will be taught katankana (another form of script) in this semester i.e. to be able to write all the foreign words in Japanese.
MTBJP 20401
Credit Units: 02
Course Contents:
Module I Comparison using adjectives, Making requests Module II Seeking permission Module III Practice of conversations on: Visiting people, Party, Meetings, After work, At a ticket vending machine etc Module IV Essays, writing formal letters
Learning Outcome
Students can speak the language describing above-mentioned topics.

Handouts, audio-aids, and self-do assignments, role-plays. Students are also encouraged to attend Japanese film festival and other such fairs and workshops organized in the capital from time to time.
Examination Scheme:
Text & References:

CHINESE IV
How many characters are there? The early Qing dynasty dictionary included nearly 50,000 characters the vast majority of which were rare accumulated characters over the centuries. An educate person in China can probably recognize around 6000 characters. The course aims at familiarizing the student with the basic aspects of speaking ability of Mandarin, the language of Mainland China. The course aims at training students in practical skills and nurturing them to interact with a Chinese person.
MTBCE 20401
Credit Units: 02
Course Contents:
Module I Dialogue Practice Observe picture and answer the question Pronunciation and intonation Character writing and stroke order. Electronic items Module II Traveling The Scenery is very beautiful Weather and climate Grammar question with bu shi . Ma? The construction yao le (Used to indicate that an action is going to take place) Time words yiqian, yiwai (Before and after). The adverb geng. Module III Going to a friend house for a visit meeting his family and talking about their customs. Fallen sick and going to the Doctor, the doctor examines, takes temperature and writes prescription. Aspect particle guo shows that an action has happened some time in the past. Progressive aspect of an actin zhengzai Also the use if zhe with it. To welcome someone and to see off someone . I cant go the airport to see you off etc. Module IV Shipment. Is this the place to checking luggage? Basic dialogue on Where do u work? Basic dialogue on This is my address Basic dialogue on I understand Chinese Basic dialogue on What job do u do? Basic dialogue on What time is it now? Module V Basic dialogue on What day (date) is it today? Basic dialogue on What is the weather like here. Basic dialogue on Do u like Chinese food? Basic dialogue on I am planning to go to China.
Examination Scheme:
Component s Weightage (%) V 10 H 10 CT 20 EE 60
Text & References:

Elementary Chinese Reader, Part-2 Lesson 31-38
PROJECT
Course Code: MTBPR 20470 Credit Units: 16
GUIDELINES FOR PROJECT FILE

Research experience is as close to a professional problem-solving activity as anything in the curriculum. It provides exposure to research methodology and an opportunity to work closely with a faculty guide. It usually requires the use of advanced concepts, a variety of experimental techniques, and state-of-the-art instrumentation. Research is genuine exploration of the unknown that leads to new knowledge which often warrants publication. But whether or not the results of a research project are publishable, the project should be communicated in the form of a research report written by the student. Sufficient time should be allowed for satisfactory completion of reports, taking into account that initial drafts should be critiqued by the faculty guide and corrected by the student at each stage. The File is the principal means by which the work carried out will be assessed and therefore great care should be taken in its preparation.
In general, the File should be comprehensive and include:

A short account of the activities that were undertaken as part of the project; A statement about the extent to which the project has achieved its stated goals. A statement about the outcomes of the evaluation and dissemination processes engaged in as part of the project; Any activities planned but not yet completed as part of the project, or as a future initiative directly resulting from the project; Any problems that have arisen that may be useful to document for future reference.
Report Layout
The report should contain the following components: Title or Cover Page. The title page should contain the following information: Project Title; Students Name; Course; Year; Supervisors Name.
Acknowledgements (optional)
Acknowledgment to any advisory or financial assistance received in the course of work may be given.
Abstract
A good "Abstract" should be straight to the point; not too descriptive but fully informative. First paragraph should state what was accomplished with regard to the objectives. The abstract does not have to be an entire summary of the project, but rather a concise summary of the scope and results of the project
Table of Contents
Titles and subtitles are to correspond exactly with those in the text.
Introduction
Here a brief introduction to the problem that is central to the project and an outline of the structure of the rest of the report should be provided. The introduction should aim to catch the imagination of the reader, so excessive details should be avoided.
Materials and Methods

This section should aim at experimental designs, materials used. Methodology should be mentioned in details including modifications if any.
Results and Discussion

Present results, discuss and compare these with those from other workers, etc. In writing these section, emphasis should be given on what has been performed and achieved in the course of the work, rather than discuss in detail what is readily available in text books. Avoid abrupt changes in contents from section to section and maintain a lucid flow throughout the thesis. An opening and closing paragraph in every chapter could be included to aid in smooth flow. Note that in writing the various secions, all figures and tables should as far as possible be next to the associated text, in the same orientation as the main text, numbered, and given appropriate titles or captions. All major equations should also be numbered and unless it is really necessary never write in point form.
Conclusion
A conclusion should be the final section in which the outcome of the work is mentioned briefly.
Future prospects Appendices

The Appendix contains material which is of interest to the reader but not an integral part of the thesis and any problem that have arisen that may be useful to document for future reference.
References:
This should include papers and books referred to in the body of the report. These should be ordered alphabetically on the author's surname. The titles of journals preferably should not be abbreviated; if they are, abbreviations must comply with an internationally recognised system. Examples: For research article: Voravuthikunchai SP, Lortheeranuwat A, Ninrprom T, Popaya W, Pongpaichit S, Supawita T. (2002) Antibacterial activity of Thai medicinal plants against enterohaemorrhagic Escherichia coli O157: H7. Clin Microbiol Infect , 8 (suppl 1): 116117. For book: Kowalski,M.(1976) Transduction of effectiveness in Rhizobium meliloti. SYMBIOTIC NITROGEN FIXATION PLANTS (editor P.S. Nutman IBP), 7: 63-67
ASSESSMENT OF THE PROJECT FILE

Essentially, marking will be based on the following criteria: the quality of the report, the technical merit of the project and the project execution. Technical merit attempts to assess the quality and depth of the intellectual efforts put into the project. Project execution is concerned with assessing how much work has been put in. The File should fulfill the following assessment objectives:
Range of Research Methods used to obtain information Execution of Research Data Analysis Analyse Quantitative/ Qualitative information Control Quality Draw Conclusions Assessment Scheme:
Continuous Evaluation: 40% (Based on punctuality, regularity of work, adherence to plan and methodology, refinements/ mid-course corrections etc. as reflected in the Project File.) Final Evaluation: 60% (Based on the Documentation in the file, Final report layout, analysis and results, achievement of objectives, presentation/ viva)

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M. Tech.

(Biotechnology) Programme Code: MTB Duration 2 Years Full Time

Programme Structure And Curriculum & Scheme of Examination 2007

AMITY UNIVERSITY UTTAR PRADESH

Amity University aims to achieve academic excellence by providing multi-faceted education

SUMMER PROJECT: 8 - 10 WEEKS THIRD SEMESTER

BIOCHEMISTRY AND METABOLIC REGULATION

Text & References:

ADVANCED MICROBIAL TECHNOLOGY

Text & References:

Text & References:

Text & References:

BIOCHEMISTRY AND MICROBIOLOGY LAB

Note: Minor variation could be there depending on the examiner.

INSTRUMENTATION IN BIOTECHNOLOGY LAB

Note: Minor variation could be there depending on the examiner.

Note: Minor variation could be there depending on the examiner.

2. Finding Sources of materials

3. Collecting the notes

4. Outlining the paper

5. Writing the first draft

6. Editing & Preparing the final Paper

Electronic journal articles:

University of Hawai'i at Manoa, Honolulu.

Unpublished theses/ dissertations:

Text & References:

BEHAVIOURAL SCIENCE - I (SELF-DEVELOPMENT AND INTERPERSONAL SKILLS)

Text & References:

Text & References:

Text & References:

Text & References:

Methods of Private study /Self help

Text & References:

Text & References:

CELL AND MOLECULAR BIOLOGY

Text & References:

RECOMBINANT DNA TECHNOLOGY

Text & References:

Text & References:

ARTIFICIAL NEURAL NETWORKS

Text & References:

Text & References:

Text & References:

Text & References:

FUNDAMENTALS OF COMPUTERS AND PROGRAMMING IN C

Text & References:

IPR, BIOSAFETY AND BIOETHICS

Text & References:

CELL, MOLECULAR BIOLOGY & RECOMBINANT DNA TECHNOLOGY LAB

Note: Minor variation could be there depending on the examiner.

BIOPROCESS TECHNOLOGY LAB

Note: Minor variation could be there depending on the examiner.

2. Finding Sources of materials

3. Collecting the notes

4. Outlining the paper

5. Writing the first draft

6. Editing & Preparing the final Paper

Electronic journal articles:

University of Hawai'i at Manoa, Honolulu.

Unpublished theses/ dissertations: