Drug Study

DRUG NAME
Generic Name: olanzapine Brand Name: Zyprexa Classification:

DOSAGE & ROUTE OF THE DRUG
MECHANISM OF ACTION OF THE DRUG
INDICATION
CONTRAINDICA TION
ADVERSE REACTION / SIDE EFFECTS
NURSING RESPONSIBILITI ES
Dosage: 10mg
Mechanism of action not fully understood; blocks dopamine receptors in the brain, depresses the RAS; blocks serotonin receptor sites; anticholinergic, antihistaminic (H1), and alpha-adrenergic blocking activity may contribute to some of its therapeutic (and adverse) actions; produces fewer extrapyramidal effects than mostantipsychotics.
Treatment of schizophrenia
Route: Oral
Antipsychotic Dopaminergic blocker
Frequency: HS Timing: 7pm
Treatment of acute mixed or manic episodes associated with bipolar 1 disorder and maintenance of bipolar 1 disorder as monotherapy, or combined with lithium or valproate
Treatment of agitation associated with schizophrenia and bipolar 1 mania (injection)
Contraindicated with allergy to olanzapine, myelo proliferative disorder s, severe CNS depression, comatose states, lactation. Use cautiously in elderly or debilitated patients, or with CV or cerebrovascular disease, dehydration, seizure disorders, Alzheimers disease, prostate enlargement, narrow-angle glaucoma, history of paralytic ileus or breast cancer, pregnancy; phenylketonuria (if using orally disintegrating tablets, contain phenylalanine).
CNS: Somnolence, dizziness, nervousness, headache, aka thisia, personality disorders, tardi ve dyskinesia, neuroleptic malignant syndrome CV: Orthostatic hypotension, peripheral edema, tachycardia GI: Constipation, abdominal pain Respiratory: Cough, pharyn gitis Other: Fever, development of diabetes mellitus
Assess for history of allergy to olanzapine. Monitor for the many possible drug interaction before beginning therapy. Encourage patient to void before taking the drug to help decrease anti cholinergic eff ects of urinary retention. Take this drug exactly as prescribed; do not change dose without consulting your health care provider.
NAME Generic Name:
DRUG NAME DRUG
DOSAGE & ROUTE OF THE DOSAGE DRUG & ROUTE OF THE DRUG Dosage:
MECHANISM OF ACTION OF THE MECHANISM DRUG OF ACTION OF THE DRUG
INDICATIO N INDICATION
Reduces anxiety,
CONTRAINDICA TION CONTRAINDICA

Hypersensitivity Kidney disease Cardiovascular disease Contraindicated inpatients hypersensitive Seizure disorder, to drug or soy protein; in myasthenia gravis patients experiencing Dehydration shock, coma, or acute Hypothyroidism alcohol intoxication(parenteral form); inpregnant women, especially in first trimester; and in children younger than age 6 months (oral form).
TION
ADVERSE REACTION / ADVERSE SIDE EFFECTS REACTION / SIDE EFFECTS CNS: headache, tremors, confusion,
NURSING RESPONSIBILITI NURSING ES RESPONSIBILITI ES
Carbamazepine 200mg Generic Name: Dosage: Brand Name: Diazepam 10mg Tegretol, Tegretol Route: XR , Equetro, Brand Name: Oral Carbatrol Route: Antenex,ApoFrequency: Diazepam,Diastat P.O ,Diazemuls,Diaze Classification: pamIntensol,Duce Timing: ne,NovoFrequency: Anticonvulstant Dipam,PMS8 pm Diazepam,Valium TID ,Vivol Classification: Anxiolytic
Decreases synaptic transmission in the CNS irritability, elation Anxiety by affecting sodium Impulse control A benzodiazepine channels in neurons that probably Acute alcohol behaviour. potentiates the Prevention of seizureswithdrawal effects of GABA, Depresses the CNS, Before endoscopic and suppresses the procedures spread of seizure activity Muscle spasm Preoperative sedation Cardio version
Timing:
Adjunct treatment For seizure disorders. Status epilepticus, severe recurrent seizures. Patients on stable regimens of antiepileptic drugs who need diazepam intermittently to control bouts of increased seizure activity.
Administer medication with food CNS: drowsiness, Assess for history restlessness, to minimize gastric of dysarthria, slurred allergy to Tablets diazepam irritation. memory loss, CV: hypotension, may be crushed if CV collapse, Use of has this difficulty drug seizures, slurred patient bradycardia. may lead to swallowing. abuse Do not speech, muscle EENT: diplopia, and addiction. crush or chew Dont blurred vision, withdraw drug weakness, lack of extended-release nystagmus. abruptly tablets. after longcoordination, GI: nausea, term use; patient withdrawal Instruct to constipation, diarrhea symptoms may lethargy, stupor take carbamazepine with rectal form. occur. around the clock, EENT: blurred Hematologic: exactly as directed. neutropenia. Monitor vision, tinnitus If a doseelderly is missed, Dias tat rectal gel is Hepatic: jaundice. patients for take as soon as GI: anorexia, contraindicated inpatients Respiratory: dizziness, ataxia, possible but not just with acute angle-closure respiratory and mental status nausea, vomiting, before next dose; do glaucoma. depression, apnea. changes. Patients not double doses. abdominal Skin: rash. cramps or are at an increased Medication should Use cautiously inpatients Other: altered libido, risk for falls. pain, diarrhea, dry be gradually with liver or renal physical discontinued to mouth, extreme impairment, depression, or psychological prevent seizures. or chronicopen-angle dependence, pain, thirst, metallic taste, May cause glaucoma. Use cautiously phlebitis at injection dizziness or weight gain in elderly and debilitated site. drowsiness. patients. Skin: rash, pruritus, Instruct patients that fever, sore alopecia, sweating, throat, mouth ulcers, dryness or thinning easy bruising, petechiae, unusual of hair bleeding, abdominal pain, chills, rash, pale stools, dark urine or jaundice should be reported. Advise patient not to take alcohol or
DRUG NAME
Generic Name: Levomepromazine
INDICATION
CONTRAINDICA TION
Dosage:
Brand Name: Route:
Classification: Frequency:
Timing:
DRUG NAME
INDICATION
CONTRAINDICA TION

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DRUG NAME

Generic Name: olanzapine Brand Name: Zyprexa Classification:

DOSAGE & ROUTE OF THE DRUG

MECHANISM OF ACTION OF THE DRUG

ADVERSE REACTION / SIDE EFFECTS

Antipsychotic Dopaminergic blocker

Frequency: HS Timing: 7pm

Treatment of agitation associated with schizophrenia and bipolar 1 mania (injection)

NAME Generic Name:

DRUG NAME DRUG

MECHANISM OF ACTION OF THE MECHANISM DRUG OF ACTION OF THE DRUG

CONTRAINDICA TION CONTRAINDICA

NURSING RESPONSIBILITI NURSING ES RESPONSIBILITI ES

DOSAGE & ROUTE OF THE DRUG

MECHANISM OF ACTION OF THE DRUG

ADVERSE REACTION / SIDE EFFECTS

Brand Name: Route:

DOSAGE & ROUTE OF THE DRUG

MECHANISM OF ACTION OF THE DRUG

ADVERSE REACTION / SIDE EFFECTS

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