Parasitology Lab Study Chart
Parasitology Lab Study Chart
Parasitology Lab Study Chart
Pathogenesis "Liver Rot", Fascioliasis - obstruction of bile duct, enlarged liver, abcesses, eosinophilia
Distribution Worldwide
Morphology Leaf-shaped, large cone shaped projections on anterior end, extensive vitellaria
Similar to Fasciola hepatica, sheep host die, cattle dead end hosts, deer; no anterior cone or shoulders Very similar to Fasciola hepatica but no human hosts, obviously larger, different snail vector; Asia Afica and Hawaii Feed on intestinal epithelial cells, ulcerations, Common hemorrhage and abcesses of SI, 25K eggs per day parasite in Orient
Snail
Largest fluke in Humans, Pigs / Intestines Humans, Dogs, Cats (RH) / lumen of bile duct Sheep, Cattle, Goats, Pigs, (rare in man) / bile ducts
Light infection: asymptomatic; chronic infection cholangiocarcinoma (bile duct cancer); Dx: eggs in stool
Far East: China, Japan Vietnam, Korea (25% Chinese immigrants) North America, Europe, Asia, Australia
1st: aquatic snail; 2nd: freshwater fish (grass carp) 1st: land snail (Cionella lubrica) 2nd: common brown ant (formica fusca) 1st: snail; 2nd: dragon fly nymph
Large adult (20-75mm L, 20mm W) branched ovaries anterior to testes, no branched ceca, acetabulum large/close to oral sucker, testes tandem in posterior, extensive vitellaria Adults with lancet appearance, weakly developed suckers, branched testes in tandem near posterior end, tegument lacks spines Pointed on both ends in adults, simple ceca, unbranced (lobate) testes, anterior to ovary
Male birds: bursa atrophies; Female: damage to oviduct > decreased or prevention of egg laying
Metacercaria in 2nd intermediate host Japan, China, Korea. (Asia), Africa, Central/South America Metacercaria in 2nd intermediate host
Bird / Bursa or Fabricius of oviduct Humans, various RH / lungs, induce host formation of fibrotic capsule Humans / villi of small intestines
Lung lesions (pseudotubercles), deep blood tinged cough, pleural pain, dyspnea; Dx: eggs in sputum
Egg hatches eaten by snail, cercaria encyst in fly muscle, eaten by bird Eating raw or undercooked crustaceans
Coffee bean fluke, small dark reddish brown color, thick testes oblique to each other, finger like lobed ovary, ovary and uterus easy to see; Eggs ovoid and operculated (flat end)
Potential human pathogens; gastric diseases, malaise, fatigue, diarrhea, fatal if damages heart; Dx: eggs > feces
Eggs cause pathology, traverse tissues, trapped eggs secrete SEA's which trigger inflammation > chronic granulomatous fibrosing lesions. Schistosomiasis (3 phases)- 1) Migratory: asymptomatic, penetration to maturity/egg production; 2) Acute: "Katayama fever" heavy infection, mainly mansoni and japonicum; 3) Chronic: granulomas of macs, etc become fibrous (pseudotubercules), eggs in liver form granulomas > cause fibrosis, eggs in gut wall ulcerate, can have bloody diarrhea (haematobium causes bloody urine), some progress to severe - fibrosis causes enlarged liver and spleen and ascites (accumulation of abdominal fluid); urinary can develop squamous cell carcinomas; Dx: eggs in excreta
Africa (Egypt, Sudan) Middle East, South America, Caribbean Japan, China, Malaysia, Philippines, Indonesia
Cercaria; eggs not operculated (require water) find snail in 5-6 hours, NO REDIA, free swimming cercariae must find host in 1-3 days; schistosomule once enters circulation
Snail, no second intermediate host; no snail hosts for human Schistosoma indigenous to USA
Humans, birds, turtles, fish / Veins of urinary bladder plexus Veins draining large intestine (inferior mesenteric plexus) Veins draining small intestine (superior mesenteric veins)
Human waste contamination of water sources, appropriate species of snail as intermediate host, using human waste as fertilizer for crops; washing, bathing, using water from contaminated streams. Control: Education, Rx with praziquantel, vector control, no vaccine