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    Pathophy

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    mharz_astillo
    This document summarizes the pathophysiology of post-streptococcal glomerulonephritis. [1] Bacteria release antigens into the bloodstream, triggering antibody formation. [2] Immune complexes deposit in the glomerular capillaries, causing inflammation. [3] This leads to swelling of the capillary membrane, infiltration of leukocytes, increased permeability, and occlusion of capillaries - reducing the kidney's ability to filter waste from the blood and causing retention of water and sodium in the body.

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    Pathophy

    Uploaded by

    mharz_astillo
    201 views2 pages
    This document summarizes the pathophysiology of post-streptococcal glomerulonephritis. [1] Bacteria release antigens into the bloodstream, triggering antibody formation. [2] Immune complexes deposit in the glomerular capillaries, causing inflammation. [3] This leads to swelling of the capillary membrane, infiltration of leukocytes, increased permeability, and occlusion of capillaries - reducing the kidney's ability to filter waste from the blood and causing retention of water and sodium in the body.

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    pathophy

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    This document summarizes the pathophysiology of post-streptococcal glomerulonephritis. [1] Bacteria release antigens into the bloodstream, triggering antibody formation. [2] Immune complexes deposit in the glomerular capillaries, causing inflammation. [3] This leads to swelling of the capillary membrane, infiltration of leukocytes, increased permeability, and occlusion of capillaries - reducing the kidney's ability to filter waste from the blood and causing retention of water and sodium in the body.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    201 views2 pages

    Pathophy

    Uploaded by

    mharz_astillo
    This document summarizes the pathophysiology of post-streptococcal glomerulonephritis. [1] Bacteria release antigens into the bloodstream, triggering antibody formation. [2] Immune complexes deposit in the glomerular capillaries, causing inflammation. [3] This leads to swelling of the capillary membrane, infiltration of leukocytes, increased permeability, and occlusion of capillaries - reducing the kidney's ability to filter waste from the blood and causing retention of water and sodium in the body.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 2

    Post – Streptococcal

    infection
    (Group A, beta hemolytic)

    Release of material from the


    organism, into the
    circulation (antigen)

    Formation of antibodies

    Immune complex reaction


    in the glomerular capillary

    Inflammatory response

    Proliferation of epithelial
    cells lining glomerolus &
    cells between endothelium
    & epithelium of capillary
    membrane

    Anemia Swelling capillary


    RBC membrane & infiltration
    Hematuria with leukocytes

    BUN &
    Cola / tea colored urine Creatinine
    ↑ Permeability of base
    +
    Urea, N , waste membrane

    Protein
    Azotemia
    Proteinuria Occlusion of the capillaries
    of the glomeruli vasospasm
    of afferent ventrioles
    Osmotic pressure

    Anasarca
    ↓ Ability to form filtrate
    from glomeruli plasma flow GFR

    Circulating
    blood volume Oliguria / Anoria

    Retention of H2O & Na;


    Blood flow to the circulatory congestion
    kidney

    RAAS (Renin Angiotensin


    aldosterone System)
    activation

    HPN Facial Edema Dyspnea (+) JVD Pulmonary


    Edema

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