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DRUGS INDICATION ACTION SIDE EFFECTS NURSING CONSIDERATION PATIENT TEACHINGS

GENERIC NAME:  HIV infection, A synthetic Adverse reactions pertain to Alert: Stop treatment immediately and notify  Inform patient that long-term effects
Epivir, Epivir-HBV with other nucleoside the combination therapy of prescriber if signs, symptoms, or laboratory of drug aren't known.
antiretrovirals analogue that lamivudine and zidovudine. abnormalities suggest pancreatitis. Monitor  Stress importance of taking drug
BRAND NAME:  Chronic hepatitis inhibits HIV and  CNS: headache, fatigue, amylase level. exactly as prescribed.
lamivudine B with evidence HBV reverse fever, neuropathy, malaise, Alert: Lactic acidosis and hepatotoxicity have  Inform patient that drug doesn't cure
of hepatitis B transcription via dizziness, insomnia and been reported. Notify prescriber if signs of HIV infection, that opportunistic
CLASSIFICATION: virus (HBV) viral DNA chain other sleep disorders, lactic acidosis or hepatotoxicity occurs. infections and other complications of
antiretroviral replication and termination. RNA- depressive disorders. Hepatitis may recur in some patients with HIV infection may still occur, and that
active liver and DNA-  EENT: nasal symptoms. chronic HBV when they stop taking drug. transmission of HIV to others through
DOSAGE: inflammation dependent DNA  GI: nausea, diarrhea, Safety and effectiveness of Epivir-HBV for sexual contact or blood contamination
Epivir polymerase vomiting, anorexia, longer than 1 year haven't been established; is still possible.
Oral solution: 10 activities. abdominal pain, abdominal optimum duration of treatment isn't known.  Teach parents or guardians the signs
mg/ml cramps, dyspepsia, Test patients for HIV before starting and symptoms of pancreatitis. Advise
Tablets: 150 mg, 300 pancreatitis. treatment and during therapy because form them to report signs and symptoms
mg  Hematologic: neutropenia, and dosage of lamivudine in Epivir-HBV aren't immediately.
anemia, appropriate for those infected with both HBV
Epivir-HBV thrombocytopenia. and HIV. If lamivudine is given to patients
Oral solution: 5  Hepatic: hepatotoxicity. with HBV and HIV, use the higher dosage
mg/ml  Metabolic: lactic acidosis. indicated for HIV therapy as part of an
Tablets: 100 mg  Musculoskeletal: appropriate combination regimen.
musculoskeletal pain, Because of a high rate of early virologic
myalgia, arthralgia. resistance, don't use triple antiretroviral
 Respiratory: cough. therapy with abacavir or didanosine,
 Skin: rash. lamivudine, and tenofovir as new treatment
 Other: chills. for never-treated or pretreated patients.
Monitor patients currently taking this therapy
and those who take it with other
antiretrovirals, and consider a different
therapy..
Monitor patient's CBC, platelet count, and renal
and liver function studies. Report
abnormalities.

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