Parental Guidance Is Recommended
Parental Guidance Is Recommended
Parental Guidance Is Recommended
recommended.
Other Name
- Pox
- Scab
- Syph
- The Great Masquerader
Treponema
pallidum
IVE
T
A T *Spirochete
S
U EN
A
C G *Slender
A
*Spiral-
shaped
*Like a cork
screw
U BA T I ON
INC
PE R I OD
10 to 90 days
3 weeks in average
MODE OF TRANSMISSION
• DIRECT CONTACT with lesions, body
secretions, mucous membrane,
blood, semen, saliva and vaginal
discharges during sexual contact
• BLOOD TRANSFUSION
• TRANSPLACENTALLY from mother to
fetus.
DIAGNOSTIC PROCEDURES:
1. Darkfield Microscopy
2. Venereal Disease Research
Laboratory serum test (VDRL)
3. Fluorescent treponemal antibody
absorption test (FTA-Abs)
4. Microhemagglutin Assay for
Treponema Pallidum (MHA-TP)
5. Rapid Plasma Reagin (RPR)
Stages of
Syphilis
1. PRIMARY SYPHILIS
• Appearance of CHANCRE, first sign of syphilis
• Appears on the site of entry or inoculation
• Most often in genitalia, lips, nipples and hands, and
in the oral cavity, anus and rectum.
• TYPICAL APPEARANCE: Painless, indurated, smooth
weeping lesions.
2. SECONDARY SYPHILIS
• 6 weeks to 6 months after primary syphilis
• Systemic disease; spirochetes circulate in the
bloodstream
• SIGNS&SYMPTOMS: Influenza-like symptoms;
GENERALIZED RASHES [palms and soles of feet]
3. LATENT SYPHILIS
A. EARLY LATENT: occur during first year after
infection and infectious lesions can recur.
B. LATE LATENT: more than 1 year in duration
after infection; not infectious except for
fetus of pregnant woman
4. TERTIARY SYPHILIS
• Occur 4 to 20 years
• “The Great Masquerader”
• SIGNS&SYMPTOMS: Benign Lesions;
Cardiovascular Syphilis; Neurosyphilis
TREATMENT
Drug of Choice:
Benzyl Penicillin G
IM, 2.4 million unit dosage
*Jarisch-Herxheimer reaction
E N TI ON
P R E V
1. EDUCATION – most important
aspect of prevention