CHD Handout

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Lipid Deposits in arteries Risk Factors/Causes

•Fats and cholesterol are deposited within


the walls of the arteries (plaque) Increased levels of cholesterol in blood •Diet high in saturated fat
•This leads to hardening of the arteries, and cholesterol
decreasing elasticity of the walls
(atherosclerosis) Nicotine increases levels of lipids in the blood, •Smoking:
Narrows blood vessels due to constriction
•Eventually leads to narrowing of lumen, Carbon monoxide and nicotine damage endothelium •Nicotine causes
reducing blood flow constriction of blood vessels,
increases blood pressure
•Production of more
blood clotting
Increased risk of
If this occurs in the coronary arteries…

fibrinogen
Thrombosis •Hypertension
•Plaque may rupture, which causes Increased risk of plaque rupture
clotting to occur at the region •High blood glucose
•Obesity
•Stress
Heart Attack •Lack of exercise
•Total blockage of coronary artery
•Supply of oxygen and nutrients cut off
•Leads to damage/death of tissue

If
th
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os
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Coronary
cu
rs
Narrowing of coronary arteries
•Insufficient supply oxygen and

Heart Disease
nutrients to cardiac muscle Factors increase
•Pain (angina) usually in chest, arm, risk of developing
shoulder may be experienced

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