Drug Study

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Some of the key drugs mentioned include ivabradin for angina, citicoline for cerebrovascular disorders, phenobarbital as an anticonvulsant, and phenytoin for seizure prevention. Lactulose is also discussed as a laxative.

Ivabradin is used for symptomatic treatment of chronic stable angina. Citicoline functions to repair cell membranes and is used for cerebrovascular disorders like stroke. Phenobarbital is an anticonvulsant and sedative/hypnotic. Phenytoin prevents tonic-clonic and complex partial seizures.

Potential side effects of phenobarbital include CNS effects like delirium, depression, and drowsiness. It can also cause respiratory depression, gastrointestinal issues, dermatological reactions, and musculoskeletal problems like arthralgia and myalgia.

GENERIC NAME BRAND NAME CLASSIFICATION MECHANISM OF ACTION INDICATION ADVERSE REACTION NURSING CONSIDERATION

Amino vita

Dosage: 1 cap
Stock dose:
Timing:TID
citicholine sodium Cholinerv Psychostimulant Citicoline is a complex Cerebrovascular GI: stomach pain,
organic molecule that disorders including diarrhea
Dosage: 1 cap functions as an Vascular: hypotension,
eschemic stroke,
Stock dose: 500 mg intermediate in the tachycardia
parkinsonism and
Timing: OD (8am) biosynthesis of cell
membrane phospholipids. head injury
It is also known as CDP-
choline or cytidine
diphosphate choline
(cytidine 5'-
diphosphocholine). CDP-
choline belongs to the
group of biomolecules in
living systems known as
nucleotides that play
important roles in cellular
metabolism.
ivabradin HCl Coralan Anti anginal Ivabradine is a pure Symptomatic Cardiovascular:
heart rate-lowering treatment bradycardia, palpitations,
Dosage: 1 tab agent, acting by selective of chronic stable supraventricular
and specific inhibition of angina extrasystoles
Stock dose: 5mg
the cardiac pectoris in corona GI: nausea, constipation
Timing: OD lunch ry artery
pacemaker Ifcurrent that
controls the diseasepatients
spontaneous diastolic w/ normal sinus
rhythm.
depolarisation in the
sinus node and regulates
heart rate. The cardiac
effects are specific to the
sinus node with no effect
on intra-atrial,
atrioventricular or
intraventricular
conduction times, nor on
myocardial contractility
or ventricular
repolarisation
phenobarbital Solfoton Therapeutic: Produces all levels of CNS Anticonvulsant CNS: Hangover, delirium, Assessment:
Anticonvulsant, depression. Depresses the depression, drowsiness, 1. Monitor drug level closely.
Dosage: 1 tablet sedative/hypnotics sensory cortex, decreases excitation, lethargy, Therapeutic level is 15 to 40
Stock dose: 60 motor activity, and alters vertigo. mcg/ml.
mg/tab Pharmacologics: cerebellar function. RESPI: Respiratory Implementation:
Timing: OD (8am) Barbiturates Inhibits transmission in the depression. 2. Educate patient that this drug
nervous system and raises GI: Constipation, can make him drowsy and less
the seizure threshold. diarrhea, nausea, anxious; do not try to get up
vomiting. after receiving this drug.
DERM: Photosensitivity, 3. Don’t abruptly stop giving the
rashes, urticaria. drug; seizures may worsen.
MS: arthralgia, myalgia,
neuralgia.
MISC: Hypersensitivity
reaction including
angioedema, and serum
sickness, physical
dependence, and
psychological
dependence.
Phenytoin Dilantin Therapeutic: Limit seizure propagation Phenytoin: CNS: ataxia, confusion, Assessment:
Antiarrhythmics by altering ion transport. Treatment or dizziness, headache, 1. Monitor phenytoin level;
Dosage: 1 Capsule and Antiarrhythmic properties prevention of tonic insomnia, nervousness, therapeutic level is 10 to 20
Stock dose: 100 anticonvulsant as a result o improvement clonic seizures and slurred speech, twitching mcg/ml.
mg/Cap in AV conduction. May also complex partial CV: hypotension 2. Monitor CBC and calcium level
Timing: ODHS Pharmacologic: decrease synaptic seizures. EENT: blurred vision, every 6 months, and
Hydantoins transmission. diplopia,nystagmus periodically monitor hepatic
Fosphenytoin is rapidly GI: nausea, vomiting function.
converted to phenytoin, Hematologic: Implementation:
which is responsible for its agranulocytosis, anemia, 1. Dilantin capsule is only PO
pharmacologic effects. leucopenia,pancytopenia form that can be given once
, thrombocytopenia daily. If any brand or form is
Hepatic: toxic hepatitis given once daily, toxic level
Metabolic: may result.
hyperglycemia 2. Give oral drug with or without
Musculoskeletal: food in a consistent manner.
osteomalacia Give with food if patient
Skin:exfoliative, complains of GI upset.
photosensitivity reaction, 3. Don’t abruptly stop giving the
toxic epidermal drug; seizure may worsen.
necrolysis 4. Maintain good oral hygiene
(regular toothbrush and
flossing) to prevent gum
disease.
Lactulose Constilac Therapeutic: Increases water content Treatment of GI: Belching, cramps, Assessment:
Laxative and softens the stool. chronic distention, flatulence, 1. Assess patient or abdominal
Dosage: 30 mL Lowers the pH of the colon constipation in diarrhea. distention, presence of bowel
Timing: OD Pharmacologic: which inhibits the diffusion adults and geriatric ENDO: Hyperglycemia. sounds and normal pattern of
Route: PO Osmotics of ammonia from the colon patients. bowel function.
into the blood, thereby 2. Assess color, consistency, and
reducing ammonia levels. the amount of stool produced.
Implementation:
1. Mix with fruit juice, water,
milk to improve flavor. May be
administered on an empty
stomach for more rapid result.
2. Darkening of solution does not
alter potency.
3. Encourage patient to increase
fluid intake to 1-2L/day.

Mucosulvan

Dosage: 1 tab
Stock dose:30 mg
Timing: BID
Risek

Dosage: 1 cap
Stock dose: 500 mg
Timing: OD pc
Vastaril MR

Dosage: 1 tab
Stock dose:
Timing: BID

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