Scribd Logo
Upload

Welcome to Scribd!

  • 98 views

    What Is Haemostasis

    Uploaded by

    shamn15
    Haemostasis is the body's response to blood vessel injury and bleeding, involving platelets, endothelial cells, and blood clotting factors working together to form a blood clot. It occurs in two stages: primary haemostasis where platelets adhere to the damaged vessel, become activated, and form a platelet plug; and secondary haemostasis or the coagulation cascade where fibrin strands form within the platelet plug to strengthen the clot while trapping red blood cells and releasing growth factors to aid tissue repair.

    Copyright:

    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd

    What Is Haemostasis

    Uploaded by

    shamn15
    98 views1 page
    Haemostasis is the body's response to blood vessel injury and bleeding, involving platelets, endothelial cells, and blood clotting factors working together to form a blood clot. It occurs in two stages: primary haemostasis where platelets adhere to the damaged vessel, become activated, and form a platelet plug; and secondary haemostasis or the coagulation cascade where fibrin strands form within the platelet plug to strengthen the clot while trapping red blood cells and releasing growth factors to aid tissue repair.

    Original Description:

    F

    Original Title

    What is Haemostasis

    Copyright

    © © All Rights Reserved

    Available Formats

    DOC, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Haemostasis is the body's response to blood vessel injury and bleeding, involving platelets, endothelial cells, and blood clotting factors working together to form a blood clot. It occurs in two stages: primary haemostasis where platelets adhere to the damaged vessel, become activated, and form a platelet plug; and secondary haemostasis or the coagulation cascade where fibrin strands form within the platelet plug to strengthen the clot while trapping red blood cells and releasing growth factors to aid tissue repair.

    Copyright:

    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    98 views1 page

    What Is Haemostasis

    Uploaded by

    shamn15
    Haemostasis is the body's response to blood vessel injury and bleeding, involving platelets, endothelial cells, and blood clotting factors working together to form a blood clot. It occurs in two stages: primary haemostasis where platelets adhere to the damaged vessel, become activated, and form a platelet plug; and secondary haemostasis or the coagulation cascade where fibrin strands form within the platelet plug to strengthen the clot while trapping red blood cells and releasing growth factors to aid tissue repair.

    Copyright:

    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    of 1

    What is Haemostasis?

    Haemostasis is the human bodys response to


    blood vessel injury and bleeding. It involves a
    co-ordinated effort between platelets,
    endothelial cells, blood clotting factors including
    tissue factor, which results in blood clot
    formation.1 Achieving haemostasis helps control
    blood loss and the release of growth factors.
    Stages of Haemostasis
    Primary Haemostasis
    1. Vaso-constriction to minimise blood loss by reducing blood flow
    to the site of damage.
    2. Damaged endothelial cells locally activate platelets.
    3. Platelet adhesion to damaged endothelium.
    4. Adhered platelets activate other nearby platelets.
    5. Activated platelets become sticky, fuse together with adhered
    platelets, forming a platelet plug.
    Secondary Haemostasis - Coagulation cascade
    1. Activated platelets in the platelet plug trap red blood cells.
    2. Fibrin strands form, strengthening the clot.
    3. Ca2+ ions, also known as clotting factor IV, are essential in
    several stages of the coagulation cascade.
    4. Further factors released during coagulation cascade include
    growth factors for tissue repair.

    You might also like