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    Pathophysiology Acute Respiratory Failure

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    Kimberly Regacho
    A 60-year-old man with a history of respiratory disease and diabetes was admitted with Klebsiella pneumoniae infection, exacerbated by pollution from vehicle emissions. This caused inflammation in his lungs, decreased ability of his cilia and macrophages to clear mucus, and damage to his alveoli and airways. As a result, he developed respiratory failure due to impaired gas exchange across the alveolar-capillary membrane and inability to effectively clear secretions.

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    Pathophysiology Acute Respiratory Failure

    Uploaded by

    Kimberly Regacho
    3K views2 pages
    A 60-year-old man with a history of respiratory disease and diabetes was admitted with Klebsiella pneumoniae infection, exacerbated by pollution from vehicle emissions. This caused inflammation in his lungs, decreased ability of his cilia and macrophages to clear mucus, and damage to his alveoli and airways. As a result, he developed respiratory failure due to impaired gas exchange across the alveolar-capillary membrane and inability to effectively clear secretions.

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    pathophysiology acute respiratory failure

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    A 60-year-old man with a history of respiratory disease and diabetes was admitted with Klebsiella pneumoniae infection, exacerbated by pollution from vehicle emissions. This caused inflammation in his lungs, decreased ability of his cilia and macrophages to clear mucus, and damage to his alveoli and airways. As a result, he developed respiratory failure due to impaired gas exchange across the alveolar-capillary membrane and inability to effectively clear secretions.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    3K views2 pages

    Pathophysiology Acute Respiratory Failure

    Uploaded by

    Kimberly Regacho
    A 60-year-old man with a history of respiratory disease and diabetes was admitted with Klebsiella pneumoniae infection, exacerbated by pollution from vehicle emissions. This caused inflammation in his lungs, decreased ability of his cilia and macrophages to clear mucus, and damage to his alveoli and airways. As a result, he developed respiratory failure due to impaired gas exchange across the alveolar-capillary membrane and inability to effectively clear secretions.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 2

    Predisposing factors, old age

    (60 years old) history of


    respiratory disease, Male,
    DM

    Precipitating factors: COPD, causative


    organism K pneumoniae, pollution
    from smoke belching vehicles

    K
    Pneumoniae

    Decrease ciliary action and


    macrophage action

    Alveolar inflammation and

    Area of decrease
    ventilation
    Capillaries are engorged in
    blood
    Stasi
    Alveolar capillary membrane
    Alveoli fill with blood and
    Atelectas
    is

    Impaired gas
    exchange related
    to alveolarcapillary
    membrane

    Inflammation and increase mucus


    production
    Destruction of alveolar
    Perbronchiolar
    Mucus plug, narrowed
    airway

    Ineffective airway clearance


    related to retained secretions

    Air
    trapping
    Airways narrow and gas flow
    prevented
    Decrease alveolar minute
    ventilation
    Decrease PaO2 level and increase in
    Hypoxem

    SNS triggers
    vasoconstriction

    Increase in PVR increase


    R-L
    Decrease
    Tissue
    hypoxemia
    Risk for fall
    related to
    insufficient
    O2 supply

    Ineffective tissue perfusion


    related to impaired transport
    of O2 across alveolar and
    capillary membrane

    Anaerobic metabolism and lactic


    acidosis
    Dizzine
    ss

    Cerebral
    depressi

    Insufficien
    t O2
    supply

    Hypercap

    Decrease O2 absoption and decrease in CO2


    elimination
    Increase O2 demand vs
    supply
    Tachypnea as
    compensatory
    Respiratory
    exhaustion
    Lost ability to
    ventilate
    O2 absorption and CO2 elimination did
    not occur
    Acute Respiratory
    Failure

    Exertiona
    l
    discomfo

    Fatigu
    e

    Activity
    intolerance
    related to

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