I found this film on the Kanopy service offered through my public library. It was a bit difficult to watch given all the cringe worthy scenarios. The description and reviews talk a lot about loneliness and there is a lot of that. However, if this movie was a real world documentary/biography I would assume Eddie to be a relatively high functioning adult with autism or a similar disorder. I felt more frustration from his character than loneliness. His condition may make it impossible to experience physically crippling depression. Folks on the spectrum tend not to completely give up or draw the conclusion that their efforts will never yield fruit hence the OCD/repetitive behavior. They get frustrated and understand that something is wrong but are more prone to lash out in a fit versus collapsing in bed for weeks on end. Given all that this movie was more about how frustrating it can be to not connect with the world like others around you seem to do so easily.
The Irene character was a monster so the actress did her job well because that was the role to be portrayed. WHAT DID I LEARN BY WATCHING THIS: If you are feeling down and want someone to agree with you or laugh at your jokes then hire a prostitute...they'll do whatever it takes as long as the meter is running.