This film is a reboot to the original Spy Kids franchise and fifth installment in the series.
First vehicle in the Spy Kids series to not costar Danny Trejo.
The first film in the Spy Kids franchise not to feature Alexa PenaVega and Daryl Sabara as Carmen and Juni Cortez, respectively.
WILHELM SCREAM: Whenever a video game character loses a life.
The parents spy organization refers to themselves as OSS. OSS was the precursor to the CIA, the American spy agency.