I can usually find lots of things to complain about in everything I watch, but toradora gives me very few. There is more than one person who likes the main character, but you always know who he will actually end up with so that doesn't matter as much. The girl is a tsundere, but they become friends quickly and that doesn't impose on the story too much. I'd like to say that they took too long to get together but really that's just personal preference and I don't think them getting together sooner would have much positive impact on the story, unless we were to have an arc where they were already together.
One thing I do wish was different is that I wish they would have realized their feeling sooner, so that there wouldn't be as much drama or people being sad in the end.
Overall, if you like slice of life anime, or drama anime, or comedy anime, or romance anime, there is a very good chance that you will like this show.