During the ice-cream-cake fiasco scene, Phil comes on screen with a video chat for Alice. Alice rushes over to turn it off and the screen is clean. When Harper and Alice start playing tug of war over the ice-cream-cake a few moments later (after the boys go to hide under the counter and are no longer running around), the screen has a frosting handprint on it.
When Artie is doing play-by-play for the Braves vs Giants game, he mentions Hudson as the starter for the Braves. When the game is shown on TV, clearly Derek Lowe is the pitcher for the Braves.
When Diane greets the grandchildren, she kisses them. The lipstick is really light with the first kiss and becomes darker at the end. It should be the other way around so Bette Midler had to re-apply lipstick so that it would show up on film.
When Artie is searched by the TSA there are (what appear to be) U.S. Marines behind him to his right wearing desert camouflage uniforms. U.S. Marines are not authorized to wear camouflage uniforms off-base unless authorized by their command(s). Also, from October 2011 through March 2014 Marines did not wear their sleeves rolled up.
At the beginning of the movie, when Artie mentions team names that he gets to announce, one is the "Rancho Cucamonga Quakes." Though that is a real team, they are a single-A team, and would not play against the Fresno Grizzlies, who are a triple-A team.
Artie's reason for being terminated is for being old-school. This reason is completely illegal and unjustifiable. His boss could have easily given him the chance to get with the times, but goes straight to termination; his boss pretty much fired him just because. Artie could've easily sued his boss and won for unjustifiable termination.
Artie mentions a kiss-cam and marriage proposal happening on the scoreboard, which is happening during a conference on the mound. These events typically are shown between innings instead of in the middle of one. And marriage proposals are typically done in the fourth inning, not the ninth.
Turner's re-creation of the famous Russ Hodges call of the "Shot Heard 'Round the World" is not exactly accurate. He fails to mention that Clint Hartung was on third when Whitey Lockman was on second.
When Artie drops Barker off at school, the car seat has the seat-belt going in front of the child and not through the car seat itself. This is not the correct way to install the car seat. However, if they hadn't done it that way it might not have been as funny.
When the organ is being played in the beginning of the film, none of the keys are being pressed.
Artie gets fired at the end of the baseball season (early September for Fresno Grizzlies). Then he goes to see his grandson's little league game (Fall Little League begins in August in Metro Atlanta). (The two older kids have school, so it must be during the school year.) Then he goes to audition to be an announcer for the X-Games--which have never been held in Atlanta.
In the beginning of the film, Artie mentions that he "feels 10 years younger" than he is, and "looks 10 years younger than that." Diane responds by mentioning that if he's 38 years old, he should paint the house. This means that Artie is 58 years old. Later, Alice says that she had Harper when she was 26, and because Harper is 12, Alice is 38 at the time of the movie. This means that Artie had Alice when he was 20, not 23 as he says.