Frank Langella went on record in an interview stating that playing Skeletor was one of his favorite roles. His young son was a huge fan and was running around the house shouting "By the power of Grayskull," so he took the role for him. He wrote some of his own lines, like: "Tell me about the loneliness of good, He-Man. Is it equal to the loneliness of evil?"
Skeletor's troops are robots because Mattel, which owned and produced the "Masters of the Universe" toyline, mandated early in production that He-Man couldn't kill anyone on screen.
Mattel, the toy company that produced the original He-Man toys, ran a contest in which the grand prize was a role in the He-Man movie. The production was under a great deal of pressure to finish in time and under budget, so director Gary Goddard had to squeeze the contest winner into the shoot. The winner, Richard Szponder, is Pigboy, who hands Skeletor his staff when he returns from Earth. He was even listed in the end credits.
Meg Foster's eyes are naturally blue/grey and with tiny pupils. She has been cast in many sci-fi/fantasy roles because of them, and jokes that she appeals to casting directors because she brings her own free special effect with her.
Dolph Lundgren said in a French magazine that working on this film was "a nightmare". The shooting schedule was five months, including two months of night shooting. He said he was approached to do a sequel during shooting, and he turned down the offer. However in an interview with the IO9 website promoting The Expendables (2010), Lundgren said he would return to appear in a new "Masters of the Universe" movie, as either a cameo or He-Man.