Dr. Bloch is named after Robert Bloch, the author of the novel upon which Psycho (1960) was based and a friend of writer H.P. Lovecraft.
As with his earlier film, Re-Animator (1985), director Stuart Gordon made use of medical advisers to be sure that the actions taken by the doctors and nurses of the film followed proper medical procedures.
The address of the house is 666 Benevolent St.