Don Ameche was originally intended for the role of Jonathan as an adult, but director Henry King was able to persuade the studio to use the unknown 22-year-old Tyrone Power in the role that would make him a star.
Loretta Young was originally suppose to star as Lady Elizabeth but she declined the role; Fox ended up putting her on suspension for her refusal.
Lloyd's became rich through the slave trade, a fact that is not mentioned in the film.