- 18 January 2008: Appointed UNICEF ambassador in Chile.
- (September 8, 2012) Lost his daughter, Blanca Vicuña, at the age 6 of multi-system organ failure after nine days hospitalized in induced coma by virus.
- Graduated from University of Chile in 2000 with a degree in arts, with a major in acting.
- Was in a relationship with Piel canela (2001) co-star Paz Bascuñán (2001-2004).
- Owns with his best friend, actor Gonzalo Valenzuela, Centro Mori (cultural center) in Santiago de Chile.
- Was in a relationship with Argentinian model Carolina Ardohain from 2005 to 2015.
- His stepfather is the Chilean billionaire Oussama Aboughazale.
- Became a father for the 1st time at age 27 when his (now ex) girlfriend Carolina Ardohain gave birth to their daughter Blanca Vicuña on May 15, 2006 in Santiago, Chile.
- Became a father for the 2nd time at age 29 when his (now ex) girlfriend Carolina Ardohain gave birth to their son Bautista Vicuña on February 29, 2008 in Buenos Aires, Argentina.
- Became a father for the 3rd time at age 33 when his (now ex) girlfriend Carolina Ardohain gave birth to their son Beltrán Vicuña on June 8, 2012 in Santiago, Chile.
- Became a father for the 4th time at age 35 when his (now ex) girlfriend Carolina Ardohain gave birth to their son Benicio Vicuña on October 12, 2014 in Santiago, Chile.
- Was in a relationship with Argentine actress The Red Thread (2016) co-star China Suárez from 2015 to 2021.
- Became a father for the 5th time at age 39 when his girlfriend China Suárez gave birth to their daughter Magnolia Vicuña on February 7, 2018 in Buenos Aires, Argentina.
- His parents, Juan Pablo Vicuña Parot and Isabel Luco Morandé, divorced when he was a young boy.
- Founded Theatre Company: "El Hijo", with friends and his then-girlfriend Manuela Oyarzún.
- Was in a relationship with Fernanda Urrejola (2004-2005).
- Younger brother of Carolina, María José (painter) and Juan Pablo (architect).
- Grew up in Santiago's commune Vitacura.
- Romantically linked with María Gracia Subercaseaux, Claudia Schmidt, Cecilia Bolocco and Milca Gili.
- Resides between Santiago and Buenos Aires.
- Became a father for the 6th time at age 41 when his girlfriend China Suárez gave birth to their son Amancio Vicuña on July 28, 2020 in Buenos Aires, Argentina.
- Ex-boyfriend of Eli Sulichín (2021-2022).
- Wrote the book "Blanca, la niña que quería volar" (2023) in memory for his daughter.
- Had extra-matrimonial affairs with his co-stars: Isabel Macedo, Romina Gaetani, Natalia Oreiro and China Suárez.
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