- Directed one Oscar-nominated performance: Nicole Kidman in Rabbit Hole (2010).
- His favorite film is A Woman Under the Influence (1974). Other favorites include Dr. Strangelove or: How I Learned to Stop Worrying and Love the Bomb (1964), Fanny and Alexander (1982), The King of Comedy (1982), Nashville (1975), Nights of Cabiria (1957), and The Conversation (1974).
- Co-wrote the song "Snapshot in LA" alongside Marion Cotillard especially for a Lady Dior advertising campaign in 2014.
- Named one of People Magazine's Breakthrough Stars of 2001.
- According to manga artist Mitsurou Kubo, he's the visual inspiration for the character of Viktor Nikiforov from the manga and hit anime Yuri on Ice.
- Listed as one of twelve "Promising New Actors of 1991" in John Willis' Screen World, Vol. 43.
- Host of Escape From Hollywood on the IFC network.
- Brother of Colin Mitchell.
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