- Mother, with husband Vondie Curtis-Hall, of son Henry Hunter Hall (b. 1996), and daughter Zora Hall (b. 1999).
- Was member of the dramatic jury at the Sundance Film Festival in 2001.
- Her name is pronounced "Casey".
- She has appeared in one film that has been selected for the National Film Registry by the Library of Congress as being "culturally, historically or aesthetically" significant: The Silence of the Lambs (1991). She has also directed one film that is in the registry: Eve's Bayou (1997).
- Directed 1 actress to an Oscar nomination: Cynthia Erivo, who was nominated for Harriet (2019).
- It was uncovered in a 2021 episode of Finding Your Roots with Henry Louis Gates, Jr. (2012) that Lemmons' third-great-grandfather was transported to the United States from Africa in the slave trade, and that she is also a distant relative of actor Kevin Bacon.
- On the show Finding Your Roots with Henry Louis Gates, Jr. (2012), she discovered that her patrilineal great-great-great-grandfather was likely born in Africa, and was brought to the U.S. in the early 1800s. His son Primus believed the family name to have already been "Lemons," or a variation, in Africa.
- She is the daughter of Dorothy Othello (Stallworth), a counselor and psychologist, and Milton Francis Lemmons, a biology teacher. She was raised mostly in Boston.
- Sister-in-law of Kevan Hall.
- Kasi means eight in Finnish.
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