Tom Cruise and Dustin Hoffman in Rain Man (1988)

Dustin Hoffman, Frances Barber, Richard Madden, Alessandro Sperduti, Guido Caprino, Annabel Scholey, Stuart Martin, and Valentina Bellè in Medici (2016)

Dustin Hoffman and Robert Evans in Marathon Man (1976)

John Cusack, Dustin Hoffman, Gene Hackman, and Rachel Weisz in Runaway Jury (2003)

Dustin Hoffman, Minnie Driver, Paul Giamatti, Rachelle Lefevre, and Rosamund Pike in Barney's Version (2010)

Dustin Hoffman, Dennis Franz, and Sean Nelson in American Buffalo (1996)

Dustin Hoffman and Warren Beatty in Ishtar (1987)

Robert De Niro, Dustin Hoffman, Barbra Streisand, Blythe Danner, Teri Polo, Ben Stiller, Jessica Alba, and Owen Wilson in Little Fockers (2010)

Dustin Hoffman and Robert Redford in All the President's Men (1976)

Brad Pitt, Robert De Niro, Dustin Hoffman, and Jason Patric in Sleepers (1996)

Dustin Hoffman, Isabelle Adjani, and Warren Beatty in Ishtar (1987)

Matthew Broderick, Sean Connery, and Dustin Hoffman in Family Business (1989)

Sean Connery and Dustin Hoffman in Family Business (1989)

Dustin Hoffman and Gene Hackman in Runaway Jury (2003)

Dustin Hoffman and Theresa Russell in Straight Time (1978)

Dustin Hoffman and Harry Dean Stanton in Straight Time (1978)

Dustin Hoffman, Harry Dean Stanton, and Rita Taggart in Straight Time (1978)

Dustin Hoffman and Edward Bunker in Straight Time (1978)

Dustin Hoffman and Sandy Baron in Straight Time (1978)

Dustin Hoffman and M. Emmet Walsh in Straight Time (1978)

Dustin Hoffman, Bill Murray, Andy Garcia, and Inés Sastre in The Lost City (2005)

Dustin Hoffman and Faye Dunaway in Little Big Man (1970)

Dustin Hoffman and Mia Farrow in John and Mary (1969)

Dustin Hoffman, Alan Rickman, Ben Whishaw, and Rachel Hurd-Wood in Perfume: The Story of a Murderer (2006)

Dustin Hoffman and Anne Bancroft in The Graduate (1967)