I've given this movie one more star than I might otherwise have because, despite its flaws, I really enjoyed this one a lot.
The only reason I saw this movie in the first place is because after watching Goodbye Charlie (1964) I wanted to see all the remakes for comparison. I found and watched three true remakes and eight similarly premised movies that I wouldn't call remakes. Of this dozen movies (including the original), I liked Sam the best by far. Natalie Knepp really sold the female version of the main character as a man suddenly in a woman's body. What's more she sold it while making the role likeable. And, she made her basically despicable character extremely amusing and likeable despite her flaws. It was easy to care how things turned out for her. Sein Kleier, Sara Scott, and Brock Harris were particularly good in their roles as well. And, none of the acting was bad. But, Natalie was the true stand-out.
That all being said, I can't help but find fault as well. The office environment, while played for laughs, is unbelievable in this day and age. Seymour and Lulu are just a bit too silly. While Brock Harris had his character pegged, he really needed to have the same hair and eye color as Natalie for one of the plot points to work.
The movie is unrated, but I would mostly call it PG13. Older kids should enjoy it safely. There is some profanity, but it's infrequent compared to a lot of movies.