Copi

El artículo compara las experimentaciones lingüísticas de Xul Solar en San Signos (2012) y de Oliverio Girondo en En la masmédula (1954). Ambas escrituras son analizadas a partir del contexto vanguardista y de los conflictos de este con el proceso inmigratorio argentino. Esta perspectiva revela afinidades (la visualidad de la común experiencia del viaje) y asimetrías, especialmente las referidas a la escucha de la alteridad sonora o exofonía (Rivera Garza 2013). El artículo propone entender la predisposicion acústica de Xul Solar como el marco crítico ideal para la recepción de la poética de En la masmédula.

Per Copi teatro e fumetto sono due possibilità, differenti e parallele, per rappresentare il mondo. Beninteso, il suo mondo. Che è al tempo stesso fantastico e iperrealista, fiabesco e grottesco, delicato e crudele, comico e tragico, basato su rigide sicurezze e sfrangiato in mille ambiguità. Sembra fin troppo facile descrivere il mondo di un autore per opposizioni, ma per Copi è davvero difficile fare altrimenti, anche se a dir la verità quello di Copi non è un mondo di semplici opposizioni, bensì un mondo mutevole e cangiante, dove qualunque elemento può essere il suo opposto ma anche tante altre cose ancora, e dove tutto si sfalda dal punto di vista semantico senza mai rinunciare alla logica cristallina della struttura formale. Del resto parliamo di un autore nato in Argentina, cresciuto in un ambiente cosmopolita e approdato nella Parigi degli anni 60 99 ; disegnatore, romanziere, autore di teatro e attore en travesti; linguisticamente trasversale tra francese, spagnolo e un pizzico d'italiano; omosessuale e anarchico. Come pensare che il mondo rispecchiato nelle sue opere possa essere chiaro e limpido?

El artículo indaga las modalidades mediante las cuales Copi, en su texto La torre de La Defensa, desmantela el archivo de la historia teatral, con el objeto de deconstruir los ideales integracionistas comunitarios, resquebrajar las narraciones identitarias estables del género y valorar la potencialidad política de las diferencias. Al mismo tiempo, se señalan las críticas del autor al contexto epocal parisino que utiliza, en la obra, como telón de fondo.

El concepto de pathosformel proviene de la obra del historiador de arte alemán Aby Warburg. A lo largo de sus prolongados y eruditos estudios sobre la imagen, este intelectual desarrolló el concepto de pathosformel como parte de su preocupación más amplia con la transmisión y supervivencia de elementos expresivos de la antigüedad, temporalmente y espacialmente, tanto en el arte elevado como en la cultura popular. La pathosformel para Warburg era un tropo visual emocionalmente cargado, que reaparecía a lo largo de la historia de la cultura visual en diversos soportes y contextos culturales. Nuestro objetivo aquí es más humilde: trazar la aparición de una serie de marcas gráficas de Saul Steinberg en el grupo de dibujantes argentinos humorísticos del período 1950-1970 que acusaron su influencia de forma más directa.

La lógica de Copi es neobarroca. ¿Pero de qué clase de barroco hablamos al decir algo semejante?
Leído en el Congreso de la Latin American Studies Association (LASA 2016/ LASA del cincuentenario) que se realizó en la ciudad de Nueva York entre los días 27 y 30 de mayo de 2016)

Este trabajo propone una lectura de la novela La guerra de las mariconas en términos de civilización y barbarie y busca mostrar cómo el clásico binomio sarmientino se reformula a través de las amazonas y los homosexuales de Copi. De las nociones clásicas de las letras decimonónicas que se siguen de tal binomio, se tendrán en cuenta, sobre todo, aquellas que vinculan lo barbárico a las conductas de naturaleza americana y lo civilizado a las culturas europeas, en particular la francesa. Para ello, se analizarán las características que vinculan a las travestis brasileñas devenidas amazonas con animales o bestias salvajes, contra aquellas que identifican a la humanidad con los homosexuales. Según se desprenderá del presente trabajo, los rasgos identificados a lo barbárico aparecen como mecanismos discursivos que explican la identificación de travestis/amazonas como divertimento erótico exótico, peligro u objeto de contemplación zoológico vinculados a un imaginario latinoamericano europeizante. En este sentido, entenderé como política cuir la desestabilización producida por las amazonas contra la cosmopolítica queer eminentemente homosexual que propone instaurar una “civilización” y buscaré contextualizar estas definiciones en términos políticos.

Coeur, Teorema y El almuerzo desnudo. Alumna: Lucila María Sancineti (35.323.523) Comisión: Paula Croci Fecha de entrega: Lunes 7 de julio Imaginación del desastre: fuera del camino iluminado El Siglo XX comienza con un aborto: la muerte y la catástrofe marcan ya sus primeros años.

Capítulo de libro. Este texto reconstruye la trayectoria biográfica y profesional de Copi en los años 1955-1970, desde su inicio como artista gráfico hasta el estreno de la obra Eva Perón. No se centra en su rol en el interior del panorama intelectual francés, sino que se concentra en otra cuestión: ¿Qué tipo de vínculo une a Copi con la política argentina del período? Lo cual nos lleva directamente a otra pregunta: ¿De qué modo es observada la trayectoria y la obra de Copi, desde Argentina, en estos años? Estas preguntas nos permiten anudar los temas que venimos mencionando: por un lado se propone que se puede hablar de un Copi político, vinculado de manera decisiva con los acontecimientos argentinos por una biografía que se transforma en obra y por sus vínculos con la comunidad del humor gráfico en los siete años que vivió en Argentina hasta 1962. En segundo lugar, se postula que el período que se extiende entre la creación de La Mujer Sentada en 1964 y el estreno de Eva Perón en 1970 constituye un período en el que el problema, desde nuestro país, es uno de importación: se intenta publicarlo en diversos medios, con escaso éxito, hasta el momento en que su exilio personal se troca en exilio político y artístico.

La novela epistolar La cité des rats comienza con una advertencia: el autor y el editor del texto invitan a los amantes de las normas consensuadas del "escribir bien" a abandonar el libro y regresar a sus lecturas favoritas. Esa nota inicial no sólo atañe a aspectos estilísticos, sino que tiene también, por supuesto, implicaciones ideológicas. En efecto, La ciudad de las ratas desafía la ética y la estética de los discursos humanistas mediante lo que César Aira ha denominado "antropología del continuo", rastreable, por ejemplo, en las condensaciones espacio-temporales o en la sistemática desarticulación de las analogías y las construcciones metafóricas. Mediante estos procedimientos, la novela transfigura el universo miniaturizado de las ratas, tierno y domesticado, en un nuevo mundo hecho de fronteras, umbrales, territorios liminares. Nos proponemos hacer una lectura de estos pasajes para analizar los modos en que la escritura de Copi hace emerger, en el espacio que une y separa el universo animal y el humano, la fuerza desestabilizadora de lo imaginario.

During vesicular transport, the assembly of the coat complexes and the selection of cargo proteins must be coordinated with the subsequent translocation of vesicles from the donor to an acceptor compartment. Here, we review recent progress toward uncovering the molecular mechanisms that connect transport vesicles to the protein machinery responsible for cytoskeleton-mediated motility. An emerging theme is that vesicle cargo proteins, either directly or through binding interactions with coat proteins, are able to influence cytoskeletal dynamics and motor protein function. Hence, a vesicle's cargo composition may help direct its intracellular motility and targeting.

La novela epistolar La cite des rats comienza con una advertencia: el autor y el editor del texto invitan a los amantes de las normas consensuadas del “escribir bien” a abandonar el libro y regresar a sus lecturas favoritas. Esa nota inicial no solo atane a aspectos estilisticos, sino que tiene tambien implicaciones ideologicas. En efecto, la novela desafia la etica y la estetica de los discursos humanistas mediante lo que Cesar Aira ha denominado “antropologia del continuo”, procedimiento con el que la novela transfigura el universo en miniatura de las ratas, tierno y domesticado, en un nuevo mundo hecho de umbrales y territorios liminares. Nos proponemos realizar una lectura de esos pasajes para investigar los modos en que la escritura de Copi hace emerger, en el espacio que une y separa el universo animal y el humano, la fuerza desestabilizadora de lo imaginario.

ARHGAP21 is a Rho family GTPase-activating protein (RhoGAP) that controls the Arp2/3 complex and F-actin dynamics at the Golgi complex by regulating the activity of the small GTPase Cdc42. ARHGAP21 is recruited to the Golgi by binding to another small GTPase, ARF1. Here, we present the crystal structure of the activated GTP-bound form of ARF1 in a complex with the Arf-binding domain (ArfBD) of ARHGAP21 at 2.1 Å resolution. We show that ArfBD comprises a PH domain adjoining a C-terminal a helix, and that ARF1 interacts with both of these structural motifs through its switch regions and triggers structural rearrangement of the PH domain. We used site-directed mutagenesis to confirm that both the PH domain and the helical motif are essential for the binding of ArfBD to ARF1 and for its recruitment to the Golgi. Our data demonstrate that two well-known small GTPase-binding motifs, the PH domain and the a helical motif, can combine to create a novel mode of binding to Arfs.

La siguiente ponencia se propone explorar la relación de sujetos "buenos" y "malos" en La guerra de las mariconas en términos de civilización y barbarie, reformulando el clásico binomio sarmientino a través de las amazonas y los homosexuales de Copi.

Golgi-derived coat protein I (COPI) vesicles mediate transport in the early secretory pathway. The minimal machinery required for COPI vesicle formation from Golgi membranes in vitro consists of (i) the hetero-heptameric protein complex coatomer, (ii) the small guanosine triphosphatase ADP-ribosylation factor 1 (Arf1) and (iii) transmembrane proteins that function as coat receptors, such as p24 proteins. Various and opposing reports exist on a role of ArfGAP1 in COPI vesicle biogenesis. In this study, we show that, in contrast to data in the literature, ArfGAP1 is not required for COPI vesicle formation. To investigate roles of ArfGAP1 in vesicle formation, we titrated the enzyme into a defined reconstitution assay to form and purify COPI vesicles. We find that catalytic amounts of Arf1GAP1 significantly reduce the yield of purified COPI vesicles and that Arf1 rather than ArfGAP1 constitutes a stoichiometric component of the COPI coat. Combining the controversial reports with the results presented in this study, we suggest a novel role for ArfGAP1 in membrane trafficking.

Transport of cargo to, through and from the Golgi complex is mediated by vesicular carriers and transient tubular connections. In this review, we describe vesicle tethering events with the understanding that similar events occur during transport via larger structures. Tethering factors can be generally divided into a group of coiled-coil proteins and a group of multi-subunit complexes. Current evidence suggests that these factors function in a variety of membrane -membrane tethering events at the Golgi complex, interact with SNARE molecules, and are regulated by small GTPases of the Rab and Arl families. D

The ArfGAP Glo3 is required for coat protein I vesicle generation in the Golgi–endoplasmic reticulum (ER) shuttle. The best-understood role of Glo3 is the stimulation of the GTPase activity of Arf1. In this study, we characterized functional domains of the ArfGAP Glo3 and identified an interaction interface for coatomer, SNAREs and cargo in the central region of Glo3 (BoCCS region). The GAP domain together with the BoCCS region is necessary and sufficient for all vital Glo3 functions. Expression of a truncated Glo3 lacking the GAP domain results in a dominant negative growth phenotype in glo3Δ cells at 37°C. This phenotype was alleviated by mutating either the BoCCS region or the Glo3 regulatory motif (GRM), or by overexpression of ER–Golgi SNAREs or the ArfGAP Gcs1. The GRM is not essential for Glo3 function; it may act as an intrinsic sensor coupling GAP activity to SNARE binding to avoid dead-end complex formation at the Golgi membrane. Our data suggest that membrane-interaction modules and cargo-sensing regions have evolved independently in ArfGAP1s versus ArfGAP2/3s.

Objective: High flow rates during cardiopulmonary bypass are assumed to increase fluid accumulation. This study aimed to determine whether two different flow rates during cardiopulmonary bypass alter the intraoperative fluid balance and extravasation rate.

Objective: High flow rates during cardiopulmonary bypass are assumed to increase fluid accumulation. This study aimed to determine whether two different flow rates during cardiopulmonary bypass alter the intraoperative fluid balance and extravasation rate.

The primary functio of salivary glands is fluid and protein secretion during feeding. Compared to mammalian systems, little is known about salivary protein secretion processes and the effect of diet on the salivary proteome in insect models. Therefore, the effect of diet nutritional quality on caterpillar labial salivary gland proteins was investigated using an unbiased global proteomic approach by nanoLC/ESI/ tandem MS. Caterpillars of the beet armyworm, Spodoptera exigua Hübner, were fed one of three diets: an artificial diet containing their self-selected protein to carbohydrate (p:c) ratio (22p:20c), an artificial diet containing a higher nutritional content but the same p:c ratio (33p:30c) or the plant Medicago truncatula Gaertn. As expected, most identified proteins were associated with secretory processes and not influenced by diet. However, some diet-specific differences were observed. Nutrient stress-associated proteins, such as peptidyl-propyl cis-trans isomerase and glucose-regulated protein94/endoplasmin, and glyceraldehyde 3-phosphate dehydrogenase were identified in the labial salivary glands of caterpillars fed nutritionally poor diets, suggesting a link between nutritional status and vesicular exocytosis. Heat shock proteins and proteins involved in endoplasmic reticulum-associated protein degradation were also abundant in the labial salivary glands of these caterpillars. In comparison, proteins associated with development, such as arylphorin, were found in labial salivary glands of caterpillars fed 33p:30c. These results suggest that caterpillars fed balanced or nutritionally-poor diets have accelerated secretion pathways compared to those fed a protein-rich diet.

Este trabajo propone una lectura de la novela La guerra de las mariconas en terminos de civilizacion y barbarie y busca mostrar como el clasico binomio sarmientino se reformula a traves de las amazonas y los homosexuales de Copi. De las nociones clasicas de las letras decimononicas que se siguen de tal binomio, se tendran en cuenta, sobre todo, aquellas que vinculan lo barbarico a las conductas de naturaleza americana y lo civilizado a las culturas europeas, en particular la francesa. Para ello, se analizaran las caracteristicas que vinculan a las travestis brasilenas devenidas amazonas con animales o bestias salvajes, contra aquellas que identifican a la humanidad con los homosexuales. Segun se desprendera del presente trabajo, los rasgos identificados a lo barbarico aparecen como mecanismos discursivos que explican la identificacion de travestis/amazonas como divertimento erotico exotico, peligro u objeto de contemplacion zoologico vinculados a un imaginario latinoamericano europe...

... Please use this identifier to cite or link to this item: Record Details. Record ID, 516830. Record Type, journalArticle. Author, Ilse Logie [801002040996] - Ghent University Ilse.Logie@UGent. be. Title, El desmontaje de los estereotipos fundadores de la identidad argentina en Copi. ...

Transport of cargo to, through and from the Golgi complex is mediated by vesicular carriers and transient tubular connections. In this review, we describe vesicle tethering events with the understanding that similar events occur during transport via larger structures. Tethering factors can be generally divided into a group of coiled-coil proteins and a group of multi-subunit complexes. Current evidence suggests that these factors function in a variety of membrane-membrane tethering events at the Golgi complex, interact with SNARE molecules, and are regulated by small GTPases of the Rab and Arl families.

Tethers are a diverse group of loosely related proteins and protein complexes grouped into 3 families based on structural and functional similarities. A well-accepted role for tethering factors is the initial attachment of transport carriers to acceptor membranes prior to fusion. However, accumulating evidence indicates that tethers are more than static bridges. Tethers have been shown to interact with components of the fusion machinery and with components involved in vesicle formation. Tethers belonging to the 3 families act at the same stage of traffic, suggesting that they mediate distinct events during vesicle tethering. Thus, multiple tether-facilitated events are required to provide selectivity to vesicle fusion. In this review, we highlight findings that support this model.

If a police officer sees something in plain view in a public place, the information collected is not classified as a search. Rule 2: If a police officer opens luggage and then observes something inside the luggage, the information collected is classified as a search. Rule 3: If a police officer listens surreptitiously to a conversation in a private place, it is classified as a search. These are three specific rules that are accepted based on specific kinds of cases that might previously have been decided by the courts. There is a more general kind of rule involved as well, called an 'analogywarranting rule' by Brewer. In the case of the drug-sniffing dog, the analogy-warranting rule (AWR) can be stated as follows (Weinreb, 2005, p. 24). AWR: If a police officer obtains information about a person or thing in a public place without intrusion on the person or taking possession of or interfering with the use of the thing, it is not a search for purposes of the Fourth Amendment. from an exceptional case (Walton, 1996, p. 92). Scheme for Argument from an Exceptional Case Major Premise : If the case of x is an exception, then the established rule can be waived in the case of x. Minor Premise : The case of a is an exception. Conclusion: Therefore, the established rule can be waived in the case of a. This form of argument is based on argument from verbal classification. The classification of x as an exception allows the application to it of the property "to be waived." The critical questions stem from the classification. Critical Questions for Argument from an Exceptional Case CQ1: Is the case of a a recognized type of exception? CQ2: If it is not a recognized case, can evidence why the established rule does not apply to it be given? CQ3: If it is a borderline case, can comparable cases be cited ? The last critical question indicates how argument from an exceptional case and its rebuttals are based on argument from analogy, as one case is compared to another. This connection will emerge even more dramatically when we consider arguments from precedent.

Anãlisis comparado de las primeras narraciones escritas en francés por Copi y Héctor Bianciotti. Citar como: Gasparini, Pablo (2006). "Exil et déplacements linguistiques: sur le 'débout français' de Copi et de Bianciotti" en Joubert, Claire (sous la direction de) Le texte etranger, Vincennes-Saint Denis, Université Paris 8..

Formation of transport vesicles involves polymerization of cytoplasmic coat proteins (COP). In COPI vesicle biogenesis, the heptameric complex coatomer is recruited to donor membranes by the interaction of multiple coatomer subunits with the budding machinery. Specific binding to the trunk domain of g-COP by the Golgi membrane protein p23 induces a conformational change that causes polymerization of the complex. Using singlepair fluorescence resonance energy transfer, we find that this conformational change takes place in individual coatomer complexes, independent of each other, and that the conformational rearrangement induced in g-COP is transmitted within the complex to its a-subunit. We suggest that capture of membrane protein machinery triggers cage formation in the COPI system.

The Arf1 GTPase-activating protein ArfGAP1 regulates vesicular traffic through the COPI system. This protein consists of N-terminal catalytic domain, lipid packing sensors (the ALPS motifs) in the central region, and a carboxy part of unknown function. The carboxy part contains several diaromatic sequences that are reminiscent of motifs known to interact with clathrin adaptors. In pull-down experiments using GSTfused peptides from rat ArfGAP1, a peptide containing a 329 WETF sequence interacted strongly with clathrin adaptors AP1 and AP2, whereas a major coatomer-binding determinant was identified within the extreme carboxy terminal peptide ( 405 AADEGWDNQNW). Mutagenesis and peptide competition experiments revealed that this determinant is required for coatomer binding to full-length ArfGAP1, and that interaction is mediated through the d-subunit of the coatomer adaptor-like subcomplex. Evidence for a role of the carboxy motif in ArfGAP1-coatomer interaction in vivo is provided by means of a reporter fusion assay. Our findings point to mechanistic differences between ArfGAP1 and the other Arf-GAPs known to function in the COPI system.

Tethers are a diverse group of loosely related proteins and protein complexes grouped into 3 families based on structural and functional similarities. A well-accepted role for tethering factors is the initial attachment of transport carriers to acceptor membranes prior to fusion. However, accumulating evidence indicates that tethers are more than static bridges. Tethers have been shown to interact with components of the fusion machinery and with components involved in vesicle formation. Tethers belonging to the 3 families act at the same stage of traffic, suggesting that they mediate distinct events during vesicle tethering. Thus, multiple tether-facilitated events are required to provide selectivity to vesicle fusion. In this review, we highlight findings that support this model.

Trafficking of secretory proteins between the endoplasmic reticulum (ER) and the Golgi apparatus depends on coat protein complexes I (COPI) and II (COPII) machineries. To date, full characterization of the distribution and dynamics of these machineries in plant cells remains elusive. Furthermore, except for a presumed linkage between COPI and COPII for the maintenance of ER protein export, the mechanisms by which COPI influences COPII-mediated protein transport from the ER in plant cells are largely uncharacterized. Here we dissect the dynamics of COPI in intact cells using live-cell imaging and fluorescence recovery after photobleaching analyses to provide insights into the distribution of COPI and COPII machineries and the mechanisms by which COPI influences COPII-mediated protein export from the ER. We found that Arf1 and coatomer are dynamically associated with the Golgi apparatus and that the COPII coat proteins Sec24 and Sec23 localize at ER export sites that track with the Golgi apparatus in tobacco leaf epidermal cells. Arf1 is also localized at additional structures that originate from the Golgi apparatus but that lack coatomer, supporting the model that Arf1 also has a coatomer-independent role for post-Golgi protein transport in plants. When ER to Golgi protein transport is inhibited by mutations that hamper Arf1-GTPase activity without directly disrupting the COPII machinery for ER protein export, Golgi markers are localized in the ER and the punctate distribution of Sec24 and Sec23 at the ER export sites is lost. These findings suggest that Golgi membrane protein distribution is maintained by the balanced action of COPI and COPII systems, and that Arf1-coatomer is most likely indirectly required for forward trafficking out of the ER due to its role in recycling components that are essential for differentiation of the ER export domains formed by the Sar1-COPII system.