El espinazo del diablo

Creencias, fiestas, devoción, historia, política, controversias y trasfondos. Usos del patrimonio cultural en el área andina.

Policromía, 2016

Ensayo acerca de la figura del mal en la cultura occidental.

Memoria Americana, 2006

El perfume del diablo, 2020

Este libro es el resultado final del proyecto de investigación «Mineros del Alto Cielo: Arqueología e Historia en Ollagüe (s. XX)» (Fondart 2017, Folio 400081). Este fue un trabajo que unió a profesionales de distintas áreas de estudio (arqueología, antropología, arquitectura), en la investigación de la historia de la explotación del azufre en la comuna de Ollagüe, Región de Antofagasta. El objetivo principal fue comprender las transformaciones económicas y socioculturales generadas por la llegada de la explotación minera del azufre durante el siglo XX en la comunidad local.

A discussion about Sokal's philosophy of science perspective and other epistemic paradigms

N Ú M . 7 0 e n e r o -F e b r e r o d e 2 0 0 7 issn: 1870-1760

Diabetologia, 2003

Aims/hypothesis. Drop-out of capillary pericytes occurs early and selectively in diabetic retinopathy. High glucose concentrations decrease replication and increase apoptosis of cultured pericytes. Since glucose activates protein kinase C, we investigated the effects of modulating this intracellular mediator on replication, cell cycle and apoptosis of cultured bovine retinal pericytes. Methods. Pericytes cultured in 5.6 or 28 mmol/l glucose were exposed to a protein kinase C activator (phorbol 12-myristate 13-acetate) and/or a selective inhibitor of its β2 isoform (LY379196). Cells were counted after 7 days. Proliferation by the tetrazolium to formazan assay and DNA synthesis by 5-bromo-2′-deoxyuridine incorporation were measured at day 4. Cell cycle by flow cytometry and apoptosis by ELISA were assessed at day 2. Results. High glucose reduced pericyte replication and increased apoptosis. Protein kinase C activation increased proliferation, while inhibition of its β2 isoform decreased it. Cell cycle was accelerated by protein kinase C activation and delayed by inhibition. Apoptosis was enhanced by protein kinase C inhibition and reduced by activation. Conclusions/interpretation. Protein kinase C inhibition amplifies the anti-proliferative and pro-apoptotic effects of high glucose on cultured pericytes, whereas stimulation reduces apoptosis and promotes proliferation both in physiological glucose and high glucose. Protein kinase C inhibition, proposed for the treatment of diabetic macular edema and proliferative retinopathy, might accelerate pericyte dropout in earlier stages when these cells are still present in retinal capillaries.

2012

Measurements of cross sections of inelastic and diffractive processes in proton-proton collisions at LHC energies were carried out with the ALICE detector. The fractions of diffractive processes in inelastic collisions were determined from a study of gaps in charged particle pseudorapidity distributions: for single diffraction (diffractive mass M X < 200 GeV/c 2 ) σ SD /σ INEL = 0.21 ± 0.03, 0.20 +0.07 −0.08 , and 0.20 +0.04 −0.07 , respectively at centre-of-mass energies