PREVENTION CONTROL AND TREATMENT OF CANCER IN UGANDA

British Journal of Cancer, 2000

Incidence rates of different cancers have been calculated for the population of Kyadondo County (Kampala, Uganda) for four time periods (1960–1966; 1967–1971; 1991–1994; 1995–1997), spanning 38 years in total. The period coincides with marked social and lifestyle changes and with the emergence of the AIDS epidemic. Most cancers have increased in incidence over time, the only exceptions being cancers of

International Journal of Cancer, 2018

Novelty & Impact: First data from this rural population in Northern Uganda, showing a cancer profile rather different to that in the urban population of Kampala (hitherto the only data on cancer in the country) with high rates of cancer of the cervix, liver and non-Hodgkin lymphoma (especially Burkitt lymphoma of childhood)

IARC scientific publications, 2011

The Kampala cancer registry was established in 1954 as a population-based cancer registry, and registration of cases is done by active methods. The registry contributed data on survival for 15 cancer sites or types registered in 1993-1997. For Kaposi sarcoma, only a random sample of the total incident cases was provided for survival study. Follow-up has been carried out predominantly by active methods, with median follow-up ranging from 4-26 months. The proportion with histologically verified diagnosis for various cancers ranged between 36-83%; death certificate only (DCO) cases were negligible; 58-92% of total registered cases were included for survival analysis. Complete follow-up at five years ranged between 47-87% for different cancers. Five-year age-standardized relative survival rates for selected cancers were Kaposi sarcoma (22%), cervix (19%), oesophagus (5%), non-Hodgkin lymphoma (26%), breast (36%) and prostate (46%). None survived beyond 5 years for cancers of the stomach...

Annals of Global Health, 2020

Background Cancer is the second leading cause of death worldwide, with over 18 million new cases and 9.6 million cancer deaths estimated to have occurred in 2018 [1]. By 2030, it is projected that there will be approximately 26 million new cancer cases and 17 million cancer deaths per year [1]. Approximately 50% of all new cancer cases and 70% of all deaths due to cancer worldwide occur in low-and middle-income countries and cancer burden in Africa is estimated to double by 2030 [2]. In Uganda, 32,000 new cases and 21,000 deaths caused by cancer occurred in 2018 and 56,238 people were living with cancer by 2018 [2]. According to the Globocan cancer statistics report of 2018 [2], the top seven cancers in Uganda-cancer of the cervix, KS, breast, prostate, NHL, liver and esophageal-account for 70% of new cancer cases. Late presentation that is estimated to stand at 80% and limited access to diagnosis and treatment services contribute to the high cancer death rate in Uganda. The World Health Organization estimates that between 30-50% of all cancers are avoidable by preventing or reducing exposure to cancer risk factors. Therefore, based on the current cancer incidence [1], a majority of the top seven cancers in Uganda, that account for 70% of new cancer cases, can be prevented by modifying their risk factors. Research into aetiologies of these most common cancers and implementation of primary

Pediatric Blood & Cancer, 2020

2019

Background: In high-income countries, haematological malignancies are the most common. World Age-Standardized Incidence Rates in Ireland averaged 142 cases per million children per year, higher than European average and lower than US average. In Africa, distribution of childhood cancers is quite similar, commonest being Kaposi sarcoma (KS), and Burkitt’s lymphoma and Hodgkin Lymphomas (HL). Among adolescent in Zimbabwe, leukaemia has highest incidence rates then osteosarcoma, NonHodgkin lymphoma (NHL) and KS. Only 30 functional cancer registries exist currently in 23 countries in Africa. Yet these are vital in planning cancer control programs. This study sought to describe the incidence of cancer among children and adolescents in Kyadondo County, Uganda from 2009 to 2014 using a population based cancer registry which is necessary for planning of cancer control programs. Methods: Descriptive cross-sectional study which involved review of data from Kampala Cancer Registry that gathers...

International Journal of Cancer, 2021

We examined trends in childhood cancer incidence in sub-Saharan Africa using data from two population-based cancer registries in Harare (Zimbabwe) and Kyadondo (Uganda) with cases classified according to the International Classification of Childhood Cancer and explored reasons for observed variations and changes. Over the whole 25-year period (1991-2015) studied, there were only small, and nonsignificant overall trends in incidence. Nevertheless, within the period, peaks in incidence occurred from 1996 to 2001 in Harare (Zimbabwe) and from 2003 to 2006 in Kyadondo (Uganda). Kaposi sarcoma and non-Hodgkin lymphoma accounted for the majority of the cases during these periods. These fluctuations in incidence rates in both registries can be linked to similar trends in the prevalence of HIV, and the availability of antiretroviral therapy. In addition, we noted that, in Harare, incidence rates dropped from 2003 to 2004 and 2007 to 2008, correlating with declines in national gross domestic product. The results indicate that the registration of childhood cancer cases in resource-poor settings is linked to the availability of diagnostic services

Cancer, 2000

BACKGROUND. There are few data concerning cancer incidence rates in contemporary West Africa. The first data from the cancer registry of Abidjan, the capital of Ivory Coast, for the period 1995-1997 are reported in the current study.