At present L-[methyl-¹¹C]methionine (L-Met) is one of the most widely used positron-emission-tomography (PET) radiopharmaceuticals. It has successfully been applied for diagnosing various tumor types, for studying biochemical processes in vivo, for estimating the metabolism of aminoacids, and for determining the rate of protein synthesis. The L-isomer of methionine is used as a radiotracer since the D-isomer is not normally metabolized.
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