The aim of the present study was to establish the changes that occur in dancers’ static body bala... more The aim of the present study was to establish the changes that occur in dancers’ static body balance indicators during rest, in case of interfering factors and in stress condition. The sample consisted of 14 advanced female folk dancers at the age of 16–20 years. The participants’ static body balance was measured at the beginning (in the autumn) and at the end (in the spring) of the eight-month dancing period. Static body balance indicators were registered on a dynamographic platform within 30 seconds, standing on bipedal on stable and unstable support surface in eyes-open (EO) and eyes-closed (EC) conditions. The Flamingo test balance control, the balance control after spinning around and jumping tests were conducted only in EO condition. The following parameters were registered: the movements of the centre of pressure (CoP) in the anterior-posterior (AP) and medio-lateral (ML) dimensions; the length, speed and area of the trajectory. According to the study, folk dancers’ CoP movem...
Our aim with the current study was to compare upper extremity and cue kinematics, and electromyog... more Our aim with the current study was to compare upper extremity and cue kinematics, and electromyographic (EMG) activation of shoulder muscles during novus (a special form of billiards) shots of different difficulty levels. Ten proficient and 10 less-skilled novus players performed 3 types of novus shots (penalties, cuts, rebounds) 10 times each. During each shot, elbow flexion and cue–forearm angles (using a movement analysis system), and surface EMG activity of the trapezius, posterior, and lateral deltoid muscles of each subject’s dominant side, were measured. Data were compared between more- and less-skilled players, and successful compared with unsuccessful shots. Elbow flexion angle among the more-skilled players was 24.5% larger (P < .001) during unsuccessful cut shots than successful ones. The more-skilled players performed successful penalty and rebound shots with 26.8% and 49.8% lower (P < .01 and P < .001, respectively) EMG activity of the trapezius muscle than uns...
Consensus on clinically valid diagnostic criteria for sarcopenia requires a systematical assessme... more Consensus on clinically valid diagnostic criteria for sarcopenia requires a systematical assessment of the association of its candidate measures of muscle mass, muscle strength, and physical performance on one side and muscle-related clinical parameters on the other side. In this study, we systematically assessed associations between serum albumin as a muscle-related parameter and muscle measures in 172 healthy young (aged 18-30 years) and 271 old participants (aged 69-81 year) from the European MYOAGE study. Muscle measures included relative muscle mass, i.e., total-and appendicular lean mass (ALM) percentage, absolute muscle mass, i.e., ALM/height 2 and total lean mass in kilograms, handgrip strength, and walking speed. Muscle measures were standardized and analyzed in multivariate linear regression models, stratified by age. Adjustment models included age, body composition, C-reactive protein and lifestyle factors. In young participants, serum albumin was positively associated with lean mass percentage (p=0.007) and with ALM percentage (p=0.001). In old participants, serum albumin was not associated with any of the muscle
Isokinetic torque deficit of the knee extensor muscles in the operated leg was measured in 21 mal... more Isokinetic torque deficit of the knee extensor muscles in the operated leg was measured in 21 male patients (mean age 26.4 +/- 1.9 years) who had undergone arthroscopic partial medial meniscectomy. The isokinetic torque testing was performed 1, 3, and 6 months postoperatively using the Cybex II dynamometer according to standard technique. Isokinetic knee extension peak torque (PT) at angular velocities of 60 degrees and 180 degrees/s was determined in both legs, and the proportional PT deficit in the operated leg was compared with that in the nonoperated leg. A significant (P&lt;0.001) isokinetic PT deficit in the operated leg in testing with angular velocity of 60 degrees and 80 degrees/s was observed at 1 month (28.6% and 31.0%, respectively) and 3 months (19.8% and 15.8%, respectively) postoperatively. At 6 months postoperatively a significant (P&lt;0.001) isokinetic PT deficit (18.2%) of the knee extensor muscles in the operated leg was observed only in testing with angular velocity of 60 degrees/s; no significant differences (P&gt;0.05) in isokinetic PT between the operated and nonoperated leg in testing with angular velocity of 180 degrees/s was found 6 months postoperatively. Thus in patients with arthroscopic partial meniscectomy the postoperative recovery of isokinetic strength of the knee extensor muscles in the injured leg is closely related to testing velocity, while it is more delayed at low than intermediate angular velocities.
Relative and absolute muscle mass and muscle strength are used as diagnostic criteria for sarcope... more Relative and absolute muscle mass and muscle strength are used as diagnostic criteria for sarcopenia. We aimed to assess which diagnostic criteria are most associated with physical performance in 180 young (18-30 years) and 281 healthy old participants (69-81 years) of the European study MYOAGE. Diagnostic criteria included relative muscle mass (total or appendicular lean mass (ALM) as percentage of body mass), absolute muscle mass (ALM/height squared and total lean mass), knee extension torque, and handgrip strength. Physical performance comprised walking speed, Timed Up and Go test (TUG), and in a subgroup physical fitness. Diagnostic criteria for sarcopenia and physical performance were standardized, and the associations were analyzed using linear regression models stratified by age category, with adjustments for age, gender, and country. In old participants, relative muscle mass was associated with faster walking speed, faster TUG, and higher physical fitness (all p<0.001). Absolute muscle mass was not associated with physical
On last year’s more popular become muscle testing method of applied kinesiology (AK). There is qu... more On last year’s more popular become muscle testing method of applied kinesiology (AK). There is question about what the tester determines with this muscle testing method – maximum voluntary contraction (MVC), force or myothatical reflex? On science this method is called subjective method. Therefore it is necessary to explain this term “week-tested muscle” and record changes in the body with objective methods. One of the recent articles show that it’s significant changes on muscle local blood flow in muscle with normal neuromuscular regulation and exchanged neuromuscular regulation or normal and week-tested muscle. Subcortical level of central nervous system (CNS) coordinates all these systems (muscle local blood flow, motor pattern of active muscle or muscle tone). On literature are articles about normal and exchanged neuromuscular regulation equally about muscle tone, but there is just few interdisciplinary articles. The aim of the study is to compare differences of muscle tone with...
The kynurenine pathway (KP) is gaining attention in several clinical fields. Recent studies show ... more The kynurenine pathway (KP) is gaining attention in several clinical fields. Recent studies show that physical exercise offers a therapeutic way to improve ratios of neurotoxic to neuroprotective KP metabolites. Antioxidant supplementation can blunt beneficial responses to physical exercise. We here studied the effects of endurance training in the form of sprint interval training (SIT; three sessions of 4–6 × 30 s cycling sprints per week for three weeks) in elderly (~65 years) men exposed to either placebo (n = 9) or the antioxidants vitamin C (1 g/day) and E (235 mg/day) (n = 11). Blood samples and muscle biopsies were taken under resting conditions in association with the first (untrained state) and last (trained state) SIT sessions. In the placebo group, the blood plasma level of the neurotoxic quinolinic acid was lower (~30%) and the neuroprotective kynurenic acid to quinolinic acid ratio was higher (~50%) in the trained than in the untrained state. Moreover, muscle biopsies sh...
Sprint interval training (SIT) has emerged as a time-efficient training regimen for young individ... more Sprint interval training (SIT) has emerged as a time-efficient training regimen for young individuals. Here, we studied whether SIT is effective also in elderly individuals and whether the training response was affected by treatment with the antioxidants vitamin C and E. Recreationally active elderly (mean age 65) men received either vitamin C (1 g/day) and vitamin E (235 mg/day) or placebo. Training consisted of nine SIT sessions (three sessions/week for three weeks of 4-6 repetitions of 30-s all-out cycling sprints) interposed by 4 min rest. Vastus lateralis muscle biopsies were taken before, 1 h after, and 24 h after the first and last SIT sessions. At the end of the three weeks of training, SIT-induced changes in relative mRNA expression of reactive oxygen/nitrogen species (ROS)- and mitochondria-related proteins, inflammatory mediators, and the sarcoplasmic reticulum Ca2+ channel, the ryanodine receptor 1 (RyR1), were blunted in the vitamin treated group. Western blots frequent...
Scientific and Technical Journal of Information Technologies, Mechanics and Optics, 2020
Предмет исследования. Предложен новый подход к анализу экспериментальных данных ходьбы, заключающ... more Предмет исследования. Предложен новый подход к анализу экспериментальных данных ходьбы, заключающийся в использовании статистик передаточных отношений. В основу исследований положены экспериментальные данные сгибания-разгибания-ротации коленного сустава, полученные в лаборатории кинезиологии и биомеханики Тартуского университета Эстонии. Методы. Для каждой из фаз данных движения были рассчитаны угловые скорости. Моменты времени изменения знака угловых скоростей представлены в качестве случайного процесса. Рассмотрена роль распределения Пуассона для моделирования распределения точек перехода через нуль. Построены корреляционные функции и спектральные плотности этих процессов. Описана роль равномерного распределения в оценке передаточных отношений. Изучена роль крестообразных связок в передаче движения. Основные результаты. В результате обработки данных с использованием статистик Пуассона и Фишера рассчитаны средние значения и дисперсия передаточных отношений. Предложена модель механизма упругой передачи движения сгибания-разгибания-ротации коленного сустава с использованием передаточного отношения и особенностей спиральной анизотропии в применении к механике крестообразных связок. Практическая значимость работы определяется поиском решения задач модернизации эластичных актуаторов, используемых в конструкциях коленных ортезов. Ключевые слова коленный сустав, сгибание/разгибание, ротация, распределения, передаточные отношения, крестообразные связки, спиральная анизотропия
The aim of this study was to assess associations between performance in the timed up-and-go (TUG)... more The aim of this study was to assess associations between performance in the timed up-and-go (TUG) and six-minute walk distance (6MWD) with physiological characteristics in young and old healthy adults. Thereto, we determined TUG, 6MWD, normalised jump power, centre of pressure displacement during 1-leg standing, forced expiratory volume in 1 s, percentage of age-predicted maximal heart rate (HR%) and height in 419 healthy young (men: 23.5 ± 2.8 years, women: 23.2 ± 2.9 years) and old (men: 74.6 ± 3.2 years, women: 74.1 ± 3.2 years) adults. Normalised jump power explained 8% and 19% of TUG in young (p = 0.025) and older men (p < 0.001), respectively. When fat mass percentage and age were added to normalised jump power, 30% of TUG was explained in older men (R2adj = 0.30, p < 0.001 to 0.106). Appendicular lean muscle mass percentage (ALM%) and age were the best determinants of TUG for older women (R2adj = 0.16, p < 0.001 to 0.01). HR% explained 17–39% of 6MWD across all group...
Chronic low-grade inflammation during aging (inflammaging) is associated with cognitive decline a... more Chronic low-grade inflammation during aging (inflammaging) is associated with cognitive decline and neurodegeneration; however, the mechanisms underlying inflammaging are unclear. We studied a population (n = 361) of healthy young and old adults from the MyoAge cohort. Peripheral levels of C-X-C motif chemokine ligand 10 (CXCL10) was found to be higher in older adults, compared with young, and negatively associated with working memory performance. This coincided with an age-related reduction in blood DNA methylation at specific CpGs within the CXCL10 gene promoter. In vitro analysis supported the role of DNA methylation in regulating CXCL10 transcription. A polymorphism (rs56061981) that altered methylation at one of these CpG sites further associated with working memory performance in 2 independent aging cohorts. Studying prefrontal cortex samples, we found higher CXCL10 protein levels in those with Alzheimer's disease, compared with aged controls. These findings support the as...
Bone mineral density declines with increasing older age. We examined the levels of circulating fa... more Bone mineral density declines with increasing older age. We examined the levels of circulating factors known to regulate bone metabolism in healthy young and older adults. The circulating levels of dickkopf-1, osteocalcin, osteoprotegerin and sclerostin were positively associated with WBMD in older adults, despite the average WBMD being lower and circulating dickkopf-1, osteoprotegerin and sclerostin being higher in old than young.
Context:The understanding of posttetanic potentiation (PTP) in human muscles induced by percutane... more Context:The understanding of posttetanic potentiation (PTP) in human muscles induced by percutaneous electrical stimulation (PES) is important for effective application of electrical stimulation in rehabilitation.Objective:To examine the effect of 7-second high-frequency (100-Hz) submaximal (25% of maximal voluntary contraction force) direct PES on contractile characteristics of the knee-extensor (KE) muscles.Design:Single-group repeated measures.Setting:Kinesiology laboratory.Subjects:13 healthy men age 18–27 years.Measurement:Peak force (PF), maximal rates of force development (RFD) and relaxation (RR) of supramaximal twitch, and PF of doublet and 10-Hz tetanic contractions before and after direct tetanic PES.Results:A significant potentiation of twitch, doublet, and 10-Hz tetanic-contraction PF has been observed at 1–5 minutes posttetanic. Twitch RFD and RR were markedly potentiated throughout the 10-minute posttetanic period.Conclusions:A brief high-frequency submaximal tetanic ...
Abstract. Working in the sitting position is often regarded as a cause for discomfort and pain in... more Abstract. Working in the sitting position is often regarded as a cause for discomfort and pain in the musculoskeletal system. The aim of the present study was to evaluate musculoskeletal symptoms in different body regions in association with the perceived fatigue and work characteristics in supermarket cashiers, who are predominantly working in the sitting position. The subjects were 67 female supermarket cashiers with the mean (±SD) age of 33.5 years, body mass index (BMI) of 23.8±0.4 kg m-2and the working time of 9.7 hours a day. All subjects completed the standardized Nordic Questionnaire and self-administered questionnaire concerning cashier’s work, biodemographic variables and fatigue. The results of this study indicated that 86.6% of subjects reported experiencing discomfort at least in one body area. Musculoskeletal symptoms in the last 6 months were localized primarily in the lower back and neck regions (67.2% and 53.7%, respectively) and in the last 7 days also in the lower...
The aim of the present study was to establish the changes that occur in dancers’ static body bala... more The aim of the present study was to establish the changes that occur in dancers’ static body balance indicators during rest, in case of interfering factors and in stress condition. The sample consisted of 14 advanced female folk dancers at the age of 16–20 years. The participants’ static body balance was measured at the beginning (in the autumn) and at the end (in the spring) of the eight-month dancing period. Static body balance indicators were registered on a dynamographic platform within 30 seconds, standing on bipedal on stable and unstable support surface in eyes-open (EO) and eyes-closed (EC) conditions. The Flamingo test balance control, the balance control after spinning around and jumping tests were conducted only in EO condition. The following parameters were registered: the movements of the centre of pressure (CoP) in the anterior-posterior (AP) and medio-lateral (ML) dimensions; the length, speed and area of the trajectory. According to the study, folk dancers’ CoP movem...
Our aim with the current study was to compare upper extremity and cue kinematics, and electromyog... more Our aim with the current study was to compare upper extremity and cue kinematics, and electromyographic (EMG) activation of shoulder muscles during novus (a special form of billiards) shots of different difficulty levels. Ten proficient and 10 less-skilled novus players performed 3 types of novus shots (penalties, cuts, rebounds) 10 times each. During each shot, elbow flexion and cue–forearm angles (using a movement analysis system), and surface EMG activity of the trapezius, posterior, and lateral deltoid muscles of each subject’s dominant side, were measured. Data were compared between more- and less-skilled players, and successful compared with unsuccessful shots. Elbow flexion angle among the more-skilled players was 24.5% larger (P < .001) during unsuccessful cut shots than successful ones. The more-skilled players performed successful penalty and rebound shots with 26.8% and 49.8% lower (P < .01 and P < .001, respectively) EMG activity of the trapezius muscle than uns...
Consensus on clinically valid diagnostic criteria for sarcopenia requires a systematical assessme... more Consensus on clinically valid diagnostic criteria for sarcopenia requires a systematical assessment of the association of its candidate measures of muscle mass, muscle strength, and physical performance on one side and muscle-related clinical parameters on the other side. In this study, we systematically assessed associations between serum albumin as a muscle-related parameter and muscle measures in 172 healthy young (aged 18-30 years) and 271 old participants (aged 69-81 year) from the European MYOAGE study. Muscle measures included relative muscle mass, i.e., total-and appendicular lean mass (ALM) percentage, absolute muscle mass, i.e., ALM/height 2 and total lean mass in kilograms, handgrip strength, and walking speed. Muscle measures were standardized and analyzed in multivariate linear regression models, stratified by age. Adjustment models included age, body composition, C-reactive protein and lifestyle factors. In young participants, serum albumin was positively associated with lean mass percentage (p=0.007) and with ALM percentage (p=0.001). In old participants, serum albumin was not associated with any of the muscle
Isokinetic torque deficit of the knee extensor muscles in the operated leg was measured in 21 mal... more Isokinetic torque deficit of the knee extensor muscles in the operated leg was measured in 21 male patients (mean age 26.4 +/- 1.9 years) who had undergone arthroscopic partial medial meniscectomy. The isokinetic torque testing was performed 1, 3, and 6 months postoperatively using the Cybex II dynamometer according to standard technique. Isokinetic knee extension peak torque (PT) at angular velocities of 60 degrees and 180 degrees/s was determined in both legs, and the proportional PT deficit in the operated leg was compared with that in the nonoperated leg. A significant (P&lt;0.001) isokinetic PT deficit in the operated leg in testing with angular velocity of 60 degrees and 80 degrees/s was observed at 1 month (28.6% and 31.0%, respectively) and 3 months (19.8% and 15.8%, respectively) postoperatively. At 6 months postoperatively a significant (P&lt;0.001) isokinetic PT deficit (18.2%) of the knee extensor muscles in the operated leg was observed only in testing with angular velocity of 60 degrees/s; no significant differences (P&gt;0.05) in isokinetic PT between the operated and nonoperated leg in testing with angular velocity of 180 degrees/s was found 6 months postoperatively. Thus in patients with arthroscopic partial meniscectomy the postoperative recovery of isokinetic strength of the knee extensor muscles in the injured leg is closely related to testing velocity, while it is more delayed at low than intermediate angular velocities.
Relative and absolute muscle mass and muscle strength are used as diagnostic criteria for sarcope... more Relative and absolute muscle mass and muscle strength are used as diagnostic criteria for sarcopenia. We aimed to assess which diagnostic criteria are most associated with physical performance in 180 young (18-30 years) and 281 healthy old participants (69-81 years) of the European study MYOAGE. Diagnostic criteria included relative muscle mass (total or appendicular lean mass (ALM) as percentage of body mass), absolute muscle mass (ALM/height squared and total lean mass), knee extension torque, and handgrip strength. Physical performance comprised walking speed, Timed Up and Go test (TUG), and in a subgroup physical fitness. Diagnostic criteria for sarcopenia and physical performance were standardized, and the associations were analyzed using linear regression models stratified by age category, with adjustments for age, gender, and country. In old participants, relative muscle mass was associated with faster walking speed, faster TUG, and higher physical fitness (all p<0.001). Absolute muscle mass was not associated with physical
On last year’s more popular become muscle testing method of applied kinesiology (AK). There is qu... more On last year’s more popular become muscle testing method of applied kinesiology (AK). There is question about what the tester determines with this muscle testing method – maximum voluntary contraction (MVC), force or myothatical reflex? On science this method is called subjective method. Therefore it is necessary to explain this term “week-tested muscle” and record changes in the body with objective methods. One of the recent articles show that it’s significant changes on muscle local blood flow in muscle with normal neuromuscular regulation and exchanged neuromuscular regulation or normal and week-tested muscle. Subcortical level of central nervous system (CNS) coordinates all these systems (muscle local blood flow, motor pattern of active muscle or muscle tone). On literature are articles about normal and exchanged neuromuscular regulation equally about muscle tone, but there is just few interdisciplinary articles. The aim of the study is to compare differences of muscle tone with...
The kynurenine pathway (KP) is gaining attention in several clinical fields. Recent studies show ... more The kynurenine pathway (KP) is gaining attention in several clinical fields. Recent studies show that physical exercise offers a therapeutic way to improve ratios of neurotoxic to neuroprotective KP metabolites. Antioxidant supplementation can blunt beneficial responses to physical exercise. We here studied the effects of endurance training in the form of sprint interval training (SIT; three sessions of 4–6 × 30 s cycling sprints per week for three weeks) in elderly (~65 years) men exposed to either placebo (n = 9) or the antioxidants vitamin C (1 g/day) and E (235 mg/day) (n = 11). Blood samples and muscle biopsies were taken under resting conditions in association with the first (untrained state) and last (trained state) SIT sessions. In the placebo group, the blood plasma level of the neurotoxic quinolinic acid was lower (~30%) and the neuroprotective kynurenic acid to quinolinic acid ratio was higher (~50%) in the trained than in the untrained state. Moreover, muscle biopsies sh...
Sprint interval training (SIT) has emerged as a time-efficient training regimen for young individ... more Sprint interval training (SIT) has emerged as a time-efficient training regimen for young individuals. Here, we studied whether SIT is effective also in elderly individuals and whether the training response was affected by treatment with the antioxidants vitamin C and E. Recreationally active elderly (mean age 65) men received either vitamin C (1 g/day) and vitamin E (235 mg/day) or placebo. Training consisted of nine SIT sessions (three sessions/week for three weeks of 4-6 repetitions of 30-s all-out cycling sprints) interposed by 4 min rest. Vastus lateralis muscle biopsies were taken before, 1 h after, and 24 h after the first and last SIT sessions. At the end of the three weeks of training, SIT-induced changes in relative mRNA expression of reactive oxygen/nitrogen species (ROS)- and mitochondria-related proteins, inflammatory mediators, and the sarcoplasmic reticulum Ca2+ channel, the ryanodine receptor 1 (RyR1), were blunted in the vitamin treated group. Western blots frequent...
Scientific and Technical Journal of Information Technologies, Mechanics and Optics, 2020
Предмет исследования. Предложен новый подход к анализу экспериментальных данных ходьбы, заключающ... more Предмет исследования. Предложен новый подход к анализу экспериментальных данных ходьбы, заключающийся в использовании статистик передаточных отношений. В основу исследований положены экспериментальные данные сгибания-разгибания-ротации коленного сустава, полученные в лаборатории кинезиологии и биомеханики Тартуского университета Эстонии. Методы. Для каждой из фаз данных движения были рассчитаны угловые скорости. Моменты времени изменения знака угловых скоростей представлены в качестве случайного процесса. Рассмотрена роль распределения Пуассона для моделирования распределения точек перехода через нуль. Построены корреляционные функции и спектральные плотности этих процессов. Описана роль равномерного распределения в оценке передаточных отношений. Изучена роль крестообразных связок в передаче движения. Основные результаты. В результате обработки данных с использованием статистик Пуассона и Фишера рассчитаны средние значения и дисперсия передаточных отношений. Предложена модель механизма упругой передачи движения сгибания-разгибания-ротации коленного сустава с использованием передаточного отношения и особенностей спиральной анизотропии в применении к механике крестообразных связок. Практическая значимость работы определяется поиском решения задач модернизации эластичных актуаторов, используемых в конструкциях коленных ортезов. Ключевые слова коленный сустав, сгибание/разгибание, ротация, распределения, передаточные отношения, крестообразные связки, спиральная анизотропия
The aim of this study was to assess associations between performance in the timed up-and-go (TUG)... more The aim of this study was to assess associations between performance in the timed up-and-go (TUG) and six-minute walk distance (6MWD) with physiological characteristics in young and old healthy adults. Thereto, we determined TUG, 6MWD, normalised jump power, centre of pressure displacement during 1-leg standing, forced expiratory volume in 1 s, percentage of age-predicted maximal heart rate (HR%) and height in 419 healthy young (men: 23.5 ± 2.8 years, women: 23.2 ± 2.9 years) and old (men: 74.6 ± 3.2 years, women: 74.1 ± 3.2 years) adults. Normalised jump power explained 8% and 19% of TUG in young (p = 0.025) and older men (p < 0.001), respectively. When fat mass percentage and age were added to normalised jump power, 30% of TUG was explained in older men (R2adj = 0.30, p < 0.001 to 0.106). Appendicular lean muscle mass percentage (ALM%) and age were the best determinants of TUG for older women (R2adj = 0.16, p < 0.001 to 0.01). HR% explained 17–39% of 6MWD across all group...
Chronic low-grade inflammation during aging (inflammaging) is associated with cognitive decline a... more Chronic low-grade inflammation during aging (inflammaging) is associated with cognitive decline and neurodegeneration; however, the mechanisms underlying inflammaging are unclear. We studied a population (n = 361) of healthy young and old adults from the MyoAge cohort. Peripheral levels of C-X-C motif chemokine ligand 10 (CXCL10) was found to be higher in older adults, compared with young, and negatively associated with working memory performance. This coincided with an age-related reduction in blood DNA methylation at specific CpGs within the CXCL10 gene promoter. In vitro analysis supported the role of DNA methylation in regulating CXCL10 transcription. A polymorphism (rs56061981) that altered methylation at one of these CpG sites further associated with working memory performance in 2 independent aging cohorts. Studying prefrontal cortex samples, we found higher CXCL10 protein levels in those with Alzheimer's disease, compared with aged controls. These findings support the as...
Bone mineral density declines with increasing older age. We examined the levels of circulating fa... more Bone mineral density declines with increasing older age. We examined the levels of circulating factors known to regulate bone metabolism in healthy young and older adults. The circulating levels of dickkopf-1, osteocalcin, osteoprotegerin and sclerostin were positively associated with WBMD in older adults, despite the average WBMD being lower and circulating dickkopf-1, osteoprotegerin and sclerostin being higher in old than young.
Context:The understanding of posttetanic potentiation (PTP) in human muscles induced by percutane... more Context:The understanding of posttetanic potentiation (PTP) in human muscles induced by percutaneous electrical stimulation (PES) is important for effective application of electrical stimulation in rehabilitation.Objective:To examine the effect of 7-second high-frequency (100-Hz) submaximal (25% of maximal voluntary contraction force) direct PES on contractile characteristics of the knee-extensor (KE) muscles.Design:Single-group repeated measures.Setting:Kinesiology laboratory.Subjects:13 healthy men age 18–27 years.Measurement:Peak force (PF), maximal rates of force development (RFD) and relaxation (RR) of supramaximal twitch, and PF of doublet and 10-Hz tetanic contractions before and after direct tetanic PES.Results:A significant potentiation of twitch, doublet, and 10-Hz tetanic-contraction PF has been observed at 1–5 minutes posttetanic. Twitch RFD and RR were markedly potentiated throughout the 10-minute posttetanic period.Conclusions:A brief high-frequency submaximal tetanic ...
Abstract. Working in the sitting position is often regarded as a cause for discomfort and pain in... more Abstract. Working in the sitting position is often regarded as a cause for discomfort and pain in the musculoskeletal system. The aim of the present study was to evaluate musculoskeletal symptoms in different body regions in association with the perceived fatigue and work characteristics in supermarket cashiers, who are predominantly working in the sitting position. The subjects were 67 female supermarket cashiers with the mean (±SD) age of 33.5 years, body mass index (BMI) of 23.8±0.4 kg m-2and the working time of 9.7 hours a day. All subjects completed the standardized Nordic Questionnaire and self-administered questionnaire concerning cashier’s work, biodemographic variables and fatigue. The results of this study indicated that 86.6% of subjects reported experiencing discomfort at least in one body area. Musculoskeletal symptoms in the last 6 months were localized primarily in the lower back and neck regions (67.2% and 53.7%, respectively) and in the last 7 days also in the lower...
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Papers by Mati Pääsuke