L’objectif de cette presente etude est de mettre en evidences les proprietes antioxydantes in vit... more L’objectif de cette presente etude est de mettre en evidences les proprietes antioxydantes in vitro d’un extrait d’ecorces d’ Anacardium occidentale (Anacardiaceae). Differentes concentrations de l’extrait ont ete testees comparativement a une solution de reference d’acide ascorbique. Le test au DPPH a ete utilise. Nos resultats indiquent que l’extrait presente une activite oxydante. Cette activite est dose-dependante et l’IC50 de l’extrait est inferieure a celle de l’acide ascorbique. Ces resultats suggerent une activite anti-oxydante de l’extrait plus importante que celle de la solution de reference (acide ascorbique). Ces resultats peuvent constituer un apport reel dans la recherche de molecules bioactives, pouvant prevenir ou traiter des pathologies liees au stress oxydatifs. Mots cles : Anacardium occidentale, activite antioxydante, DPPH. ABSTRACT The aim of this study is to show the in vitro anti-free radical effects of the extract of bark of Anacardium occidentale (Anacardia...
Combretum micranthum (kinkeliba) is one of the most used medicinal plants in Senegal. However, it... more Combretum micranthum (kinkeliba) is one of the most used medicinal plants in Senegal. However, its commercialization is poorly studied. The objective of this study is to analyze the commercialization of Combretum micranthum in Senegal. The study was carried out in two main regions of kinkeliba marketing in Senegal: Dakar, where kinkeliba is marketed; and Thies, where kinkeliba is produced and marketed. Structured and unstructured surveys were administered to different categories of stakeholders: herbalists / traditional practitioners, collectors/ suppliers, retailers and consumers. Production sites that supply Dakar include the following: Diass, Sindia, Kiniabour, Pout, Thies Lalane. The main sales points in Dakar are the Thiaroye and Grand Yoff markets. The kinkeliba marketing chain has short channels and women are the main stakeholders. Procurement is done by harvesting in the natural environment and by purchase for herbalists / traditional practitioners. The benefits and added va...
This study examines the total polyphenol content and the antiradical properties of extract from C... more This study examines the total polyphenol content and the antiradical properties of extract from Combretum micranthum leaves harvested in Diass, Sandiara in west-central Senegal and in Essyl in the south, during the rainy season versus the after-rainy season. The total polyphenol content expressed in tannic acid equivalent per 100 g of dry matter during the rainy season and the after-rainy season are respectively:
Combretum micranthum (kinkeliba) is one of the most used medicinal plants in Senegal. However, it... more Combretum micranthum (kinkeliba) is one of the most used medicinal plants in Senegal. However, its commercialization is poorly studied. The objective of this study is to analyze the commercialization of Combretum micranthum in Senegal. The study was carried out in two main regions of kinkeliba marketing in Senegal: Dakar, where kinkeliba is marketed; and Thies, where kinkeliba is produced and marketed. Structured and unstructured surveys were administered to different categories of stakeholders: herbalists / traditional practitioners, collectors/ suppliers, retailers and consumers. Production sites that supply Dakar include the following: Diass, Sindia, Kiniabour, Pout, Thies Lalane. The main sales points in Dakar are the Thiaroye and Grand Yoff markets. The kinkeliba marketing chain has short channels and women are the main stakeholders. Procurement is done by harvesting in the natural environment and by purchase for herbalists / traditional practitioners. The benefits and added va...
Background: In recent decades, fertility appears to be increasing, which is a public health probl... more Background: In recent decades, fertility appears to be increasing, which is a public health problem and involving all health actors. Thus, the varicocele is one of the causes affects about 12% of the male population. Aim/Objective: The aim of this study is to inventory the plants used against the treatment of varicocele because the populations often resort to phytotherapy. Methods: It is in this sense that a survey of twenty two traditional practitioners and six herbalists were conducted to identify the plants used in the management of varicocele in the Dakar and Mbour departments. Original Research Article Diatta et al.; AJRIB, 3(1): 8-17, 2020; Article no.AJRIB.52855 9 Results: Thirty five plants could be identified and divided into thirty three genera and twenty two families. Fabaceae was the most represented family with 5 species followed by Anacardiaceae (4 species), Asclepiadaceae, Combretaceae, Menispermaceae, Rhamnaceae, Rubiaceae and Zingiberaceae each with 2 species, Annon...
International Journal of Biological and Chemical Sciences, 2015
L'objectif de la présente étude était d'évaluer l'activité antioxydante des extraits des feuilles... more L'objectif de la présente étude était d'évaluer l'activité antioxydante des extraits des feuilles de Vitex doniana par spectrophotométrie en utilisant les méthodes de piégeage des radicaux libres 2,2-diphényl-1picryl-hydrazyle (DPPH •) et acide 2,2'-azino-bis-(3-éthylbenzothiazoline-6-sulfonique) (ABTS +•). Une extraction éthanolique des feuilles de Vitex doniana a été effectuée au Soxhlet. L'extrait sec recueilli a été redissout dans de l'eau puis fractionné en utilisant successivement de l'hexane, du dichlorométhane et de l'acétate d'éthyle. Les propriétés antioxydantes de l'extrait éthanolique et celles de ses différentes fractions ont été évaluées aux concentrations de 2,5 ; 10 ; 100 et 200 µg/mL. Les pourcentages d'inhibition (PI) expriment l'effet antioxydant mesuré. L'extrait éthanolique et ses différentes fractions ont présenté une activité de piégeage des deux radicaux libres. Lors des tests d'inhibition de l'absorbance du radical DPPH • , les PI ont varié de (18,15±0,01)% pour la fraction hexanique (2,5 µg/mL) à (92,45±0,01)% pour la fraction d'acétate d'éthyle (100 µg/mL). Avec le radical ABTS +• , les PI ont varié de (52,76±0,05)% pour la fraction hexanique (2,5 µg/mL) à (98,27±0,12)% pour la fraction d'acétate d'éthyle (100 µg/mL). Ainsi, l'extrait éthanolique des feuilles de Vitex doniana et ses différentes fractions possèdent un pouvoir antioxydant significatif.
Journal of Physiology and Pharmacology Advances, 2015
The aim of this study was to determine whether an hydro-alcoolic extract of cloves of Allium sati... more The aim of this study was to determine whether an hydro-alcoolic extract of cloves of Allium sativum is able to induce a relaxant effect in the rat aorta and so the mechanism underlying this effect. Rat aortic rings were suspended in organ chambers for recording of changes in isometric forces. Rings with endothelium were incubated or not with L-Nitro Arginine Methyl Ester (L-NAME) to block NO synthase, before contraction with adrenalin and a concentration relaxation curve to the hydro-alcoolic extract. In some experiments, endothelium was removed before contraction with adrenalin and concentration relaxation to the extract. Prevent effect of the extract was determine with contraction curve to adrenaline in rings with and without endothelium incubated with the extract of Allium sativum. The hydro-alcoolic extract of Allium sativum induces a vasodilatatory effect in the rat aorta contracted with adrenalin. This effect is not endothelium-dependent and is not mediated by NO. Furthermore the extract incubated with aorta rings, is able to prevent the contraction induced by adrenalin. Allium sativum induces vascular relaxation which can explain the benefic effect of this plant in treatment of high blood pressure in Senegal.
In Africa, the use of plants for therapeutic purposes is an ancient practice. In recent years, mu... more In Africa, the use of plants for therapeutic purposes is an ancient practice. In recent years, much scientific work has been spent to the chemistry and toxicology of medicinal plants; there is a particular focus on natural antioxidants in relation to their various therapeutic properties. Therefore, the purpose of our study is to determine the antioxidant activity of aqueous and hydroethanol extracts from the leaves of Azadirachta indica A. Juss a plant known for its many pharmacological properties. The leaves of Azadirachta indica A. Juss were oven dried at 60 degrees for 24 hours and reduced to a fine powder. And, the powder is first extracted with distilled water to obtain the aqueous extract, then with a mixture of distilled water and ethanol 50/50 (v / v) to obtain the hydroethanol extract. Short Research Article Diatta et al.; AJRIB, 2(4): 1-8, 2019; Article no.AJRIB.50878 2 Antioxidant activity was done through the DPPH test, the FRAP method and the fixation of the radical nit...
En Afrique, l'espèce Zanthoxylum zanthoxyloides est largement utilisée dans le traitement de nomb... more En Afrique, l'espèce Zanthoxylum zanthoxyloides est largement utilisée dans le traitement de nombreuses affections comme la drépanocytose, les maladies inflammatoires et les douleurs. Les racines restent les parties de la plante les plus utilisées, ce qui pose le problème de la survie et de l'exploitation durable de l'espèce. Cette présente étude tente de trouver une alternative à l'utilisation des racines en médecine traditionnelle. L'activité anti-inflammatoire a été évaluée sur un modèle d'oedème induit par la carraghénine sur la patte de rat Wistar. L'activité analgésique a été quant à elle, évaluée sur un modèle de douleur à l'acide acétique sur la souris. L'extrait hydroalcoolique de feuilles montre une activité anti-inflammatoire à la dose de 100 mg/kg per os, avec des pourcentages d'inhibition de l'oedème de 36,64% et 50,13% respectivement à la quatrième et sixième heures. A la sixième heure, la dose de 300 mg/kg a une activité supérieure à celle de l'acide acétylsalicylique à la dose de 100 mg/kg, avec des pourcentages d'inhibition respectifs de 85,28% et 55,93%. Cet extrait à la dose de 300 mg/kg est doublé d'un effet analgésique qui est comparable à celui de l'acide acétylsalicylique à la dose de 100 mg/kg per os avec des pourcentages d'inhibition de la douleur respectifs de 72,91% et 73,21%. Ces résultats montrent que les feuilles et les racines sont douées de propriétés anti-inflammatoires et analgésiques. Dans une perspective de sauvegarde de l'espèce, les feuilles pourraient être utilisées à la place des racines dans la prise en charge de ces pathologies.
An ethno-apicultural survey was carried out for the plant species pollinated by honey bees in the... more An ethno-apicultural survey was carried out for the plant species pollinated by honey bees in the green district of Casamance (South Senegal). This survey followed a well-established questionnaire concerning beekeepers in these areas. The listed melliferous flora was made of 61 species either. It’s divided into 58 genera and 30 families though the most represented are in decreasing order Fabaceae with 12 species (19.67%) followed by Rutaceae and Malvaceae with 4 species (6.55% each), Arecaceae, Anacardiaceae, Combretaceae, Gramineae, Myrtaceae, with 3 species (4.91% each), then Chrysobalanaceae, Lamiaceae, Meliaceae and Rubiaceae with 2 species (3.27% each) and then Acanthaceae, Asteraceae, Canabaceae, Verbenaceae, Apocynaceae, Bignoniaceae, Annonaceae, Hymenocardiaceae, Icacinaceae, Lauraceae, Moringaceae, Musaceae, Celastraceae, Rhizophoraceae, Sapindaceae, Sterculiceae, Moraceae, Ochnaceae, with 1 species (1.63% each). Melliferous plants include 47.54% nectariferous plants follow...
Use of plants as remedies dates back to the time of the oldest civilizations. Among these active ... more Use of plants as remedies dates back to the time of the oldest civilizations. Among these active ingredients, polyphenols play an important role. Piliostigma reticulatum, a plant whose barks are rich in condensed tannin is often used as an anti-inflammatory. The purpose of this work was to correlate the anti-inflammatory activity of extracts with their chemical composition through chromatography fractionation analyses (HPLC-DAD and HPLC-MS). The barks were extracted by moderate hydroethanol decoction followed by silica gel splitting with successively ethyl acetate, methanol and water. Anti-inflammatory activity was evaluated by the method of carrageenan induced hind paw edema in Wistar rats. The chemical study was carried out by HPLC-DAD and HPLC-MS after isolation of the compounds by fractionation on Sephadex LH-20 gel. The bark hydroethanolic extract had shown ability to inhibit significantly the inflammation induced by carraghenan. Among the hydroethanolic bark extract fractions...
Spilanthes oleracea Jacq. is an herbaceous plant whose scientific literature attributes among oth... more Spilanthes oleracea Jacq. is an herbaceous plant whose scientific literature attributes among others, anti-malarial and anti-bilharzia properties. These virtues justify the placing on the market of drugs based on the plant.Our study consisted on the one hand to evaluate the biomass of the plant on a soil of dune amended and on soil of unamended dune and to test its vegetative multiplication by transplanting, cuttings and layering.The results show that the growth of the species is greater on dune soil amended with an average biomass of 106.06 g compared to 71.06 g for un-amended soil plants. The transplanting of the plants and the layering were techniques that made it possible to multiply the plants.Spilanthes oleracea Jacq. can be produced using this agronomic data.
Background: The use of plants for healing dates back to very remote times. Nowadays with the acce... more Background: The use of plants for healing dates back to very remote times. Nowadays with the accession of new diseases plants are increasingly used for the formulation of new drugs able to overcome the many diseases (cancer, atherosclerosis) often caused by the disorder of the system prooxidant/antioxidant. Aim/Objective: On the strength of this observation, the research of an antioxidant plant is essential, hence the aim of this study, which is to determine the antioxidant activity of the stalk and the fruit of Solanum aethiopicum L. Methods: The fruits and stalk were washed, cut into fine slats, then dried in the incubator for three days and finally crushed into powder. An extraction by decoction with ethanol (stalks and fruits) and water (fruit) was subsequently carried out to obtain three extracts (ethanol and water). Antioxidant activity was evaluated through the FRAP method, and the trapping of radical DPPH. Results: For the FRAP method, at the highest concentration (1 mg/ml) ...
Asian Journal of Research in Medical and Pharmaceutical Sciences
Background : Nowadays with the appearance of diseases such as cancer, atherosclerosis, free radic... more Background : Nowadays with the appearance of diseases such as cancer, atherosclerosis, free radicals are often singled out. What motivates scientific research in natural antioxidants. Aim/Objective : The aim of this study was to determine the antioxidant activity of the stalks and the fruit of Solanum melongena L. Study Duration : The period of the study was done on 25th July, 2015 at the Department of Pharmacy, Faculty of Medecine, Pharmacy and Odontology, University of Dakar, Senegal. Methodology : Antioxidant activity was evaluated through two methods (DPPH and FRAP). Results : For the FRAP test, at the highest concentration (83.3 µg/ml) the aqueous extract of the fruit (0.90±0.08) has a higher reducing power compared to those of ethanol extracts from the fruit (0.77±0.41) and the stalk (0.85±0.004). These results remain inferior to that of tannic acid (0.95± 0.0005). The DPPH test reveals that the ethanolic extract of the fruit is more effective in reducing the free radical DPPH...
Background: In Africa, particularly in Senegal, 70% of the population resort to traditional medic... more Background: In Africa, particularly in Senegal, 70% of the population resort to traditional medicine. Aim/Objective: The aim of this study is to inventory the plants used to the the treatment of erectile dysfunction, hypertension, diabetes etc because the populations often resort to phytotherapy. Methods: Fifty traditional practitioners, fifty herbalists and fifty resources persons were conducted to identify the plants used in the management of affections in the Tivaouane department. Results: Ninety seven plants could be identified and divided into eighty nine genera and forty eight families. Thus, Fabaceae families with 18 species, Euphorbiaceae (8 species), Combretaceae (5 species), Malvaceae (4 species), Anacardiaceae, Annonaceae, Asteraceae, Meliaceae Myrtaceae and Poaceae each with 3 species and Asclepiadaceae, Liliaceae, Lythraceae, Loganaceae and Menispermaceae each with 2 species; Apocynaceae, Balanitaceae, Bignoniaceae, Capparidaceae, Caricaceae, Casuarinaceae, Celastracea...
Asian Journal of Research in Medical and Pharmaceutical Sciences
HIV / AIDS infection is characterized by the reduction of the body's defenses favoring the oc... more HIV / AIDS infection is characterized by the reduction of the body's defenses favoring the occurrence "opportunistic" infections, as bronchitis, mycoses and tuberculosis etc. Thus, to fight against this virus, antiretrovirals are used. The Ziguinchor district (Senegal) has a higher seroprevalence rate of 2.2% above the national average of 0.7%. It is in this sense that a survey of two herbalists, 35 tradipraticians and eight resource persons was conducted to identify the plants used in the management of opportunistic AIDS diseases because as the populations often resort to phytotherapy. 88 plants were identified and divided into 79 genera and 38 families. Some species were mentioned very more frequently and in many diseases. These are: Cordila pinnata Poir. (78%), Guiera senegalensis (73.1%), Khaya senegalensis (67%), Icacina oliviformis (55%), Terminalia macroptera (55%), Cassia sieberiana (47%), etc. Leaves and roots constituted the greatest use in the form of macera...
This study has surveyed honey plants used by Apis mellifera in the Great Green Wall of Senegal b... more This study has surveyed honey plants used by Apis mellifera in the Great Green Wall of Senegal by involving 38 people (21 in Widou, 17 in Koyli Alpha). The study revealed seventeen species divided into fourteen genera and nine families. Fabaceae was the most represented family with 5 species followed by Combretaceae (3 species), Malvaceae and Rutaceae each with 2 species, and Anacardiaceae, Balanitaceae, Rhamnaceae, Sterculiaceae, Meliaceae each with one species. The most frequent melliferous plant species were : Combretum glutinosum, Guiera senegalensis, Balanites aegyptiaca, Acacia radiana, Lannea acida, Terminalia avicennoides, Sclerocarya birrea, Sterculia setigera and Maytenus senegalensis. The trees were more large with 58.82% followed by shrubs (35.29%) and herbs (5.88%). Spontaneous plants represent 76.47% and cultivated plants represent 23.53%. The melliferous flora was largely dominated by African and Afro-Indian species, which together accounted for 70.58% of the spec...
L’objectif de cette presente etude est de mettre en evidences les proprietes antioxydantes in vit... more L’objectif de cette presente etude est de mettre en evidences les proprietes antioxydantes in vitro d’un extrait d’ecorces d’ Anacardium occidentale (Anacardiaceae). Differentes concentrations de l’extrait ont ete testees comparativement a une solution de reference d’acide ascorbique. Le test au DPPH a ete utilise. Nos resultats indiquent que l’extrait presente une activite oxydante. Cette activite est dose-dependante et l’IC50 de l’extrait est inferieure a celle de l’acide ascorbique. Ces resultats suggerent une activite anti-oxydante de l’extrait plus importante que celle de la solution de reference (acide ascorbique). Ces resultats peuvent constituer un apport reel dans la recherche de molecules bioactives, pouvant prevenir ou traiter des pathologies liees au stress oxydatifs. Mots cles : Anacardium occidentale, activite antioxydante, DPPH. ABSTRACT The aim of this study is to show the in vitro anti-free radical effects of the extract of bark of Anacardium occidentale (Anacardia...
Combretum micranthum (kinkeliba) is one of the most used medicinal plants in Senegal. However, it... more Combretum micranthum (kinkeliba) is one of the most used medicinal plants in Senegal. However, its commercialization is poorly studied. The objective of this study is to analyze the commercialization of Combretum micranthum in Senegal. The study was carried out in two main regions of kinkeliba marketing in Senegal: Dakar, where kinkeliba is marketed; and Thies, where kinkeliba is produced and marketed. Structured and unstructured surveys were administered to different categories of stakeholders: herbalists / traditional practitioners, collectors/ suppliers, retailers and consumers. Production sites that supply Dakar include the following: Diass, Sindia, Kiniabour, Pout, Thies Lalane. The main sales points in Dakar are the Thiaroye and Grand Yoff markets. The kinkeliba marketing chain has short channels and women are the main stakeholders. Procurement is done by harvesting in the natural environment and by purchase for herbalists / traditional practitioners. The benefits and added va...
This study examines the total polyphenol content and the antiradical properties of extract from C... more This study examines the total polyphenol content and the antiradical properties of extract from Combretum micranthum leaves harvested in Diass, Sandiara in west-central Senegal and in Essyl in the south, during the rainy season versus the after-rainy season. The total polyphenol content expressed in tannic acid equivalent per 100 g of dry matter during the rainy season and the after-rainy season are respectively:
Combretum micranthum (kinkeliba) is one of the most used medicinal plants in Senegal. However, it... more Combretum micranthum (kinkeliba) is one of the most used medicinal plants in Senegal. However, its commercialization is poorly studied. The objective of this study is to analyze the commercialization of Combretum micranthum in Senegal. The study was carried out in two main regions of kinkeliba marketing in Senegal: Dakar, where kinkeliba is marketed; and Thies, where kinkeliba is produced and marketed. Structured and unstructured surveys were administered to different categories of stakeholders: herbalists / traditional practitioners, collectors/ suppliers, retailers and consumers. Production sites that supply Dakar include the following: Diass, Sindia, Kiniabour, Pout, Thies Lalane. The main sales points in Dakar are the Thiaroye and Grand Yoff markets. The kinkeliba marketing chain has short channels and women are the main stakeholders. Procurement is done by harvesting in the natural environment and by purchase for herbalists / traditional practitioners. The benefits and added va...
Background: In recent decades, fertility appears to be increasing, which is a public health probl... more Background: In recent decades, fertility appears to be increasing, which is a public health problem and involving all health actors. Thus, the varicocele is one of the causes affects about 12% of the male population. Aim/Objective: The aim of this study is to inventory the plants used against the treatment of varicocele because the populations often resort to phytotherapy. Methods: It is in this sense that a survey of twenty two traditional practitioners and six herbalists were conducted to identify the plants used in the management of varicocele in the Dakar and Mbour departments. Original Research Article Diatta et al.; AJRIB, 3(1): 8-17, 2020; Article no.AJRIB.52855 9 Results: Thirty five plants could be identified and divided into thirty three genera and twenty two families. Fabaceae was the most represented family with 5 species followed by Anacardiaceae (4 species), Asclepiadaceae, Combretaceae, Menispermaceae, Rhamnaceae, Rubiaceae and Zingiberaceae each with 2 species, Annon...
International Journal of Biological and Chemical Sciences, 2015
L'objectif de la présente étude était d'évaluer l'activité antioxydante des extraits des feuilles... more L'objectif de la présente étude était d'évaluer l'activité antioxydante des extraits des feuilles de Vitex doniana par spectrophotométrie en utilisant les méthodes de piégeage des radicaux libres 2,2-diphényl-1picryl-hydrazyle (DPPH •) et acide 2,2'-azino-bis-(3-éthylbenzothiazoline-6-sulfonique) (ABTS +•). Une extraction éthanolique des feuilles de Vitex doniana a été effectuée au Soxhlet. L'extrait sec recueilli a été redissout dans de l'eau puis fractionné en utilisant successivement de l'hexane, du dichlorométhane et de l'acétate d'éthyle. Les propriétés antioxydantes de l'extrait éthanolique et celles de ses différentes fractions ont été évaluées aux concentrations de 2,5 ; 10 ; 100 et 200 µg/mL. Les pourcentages d'inhibition (PI) expriment l'effet antioxydant mesuré. L'extrait éthanolique et ses différentes fractions ont présenté une activité de piégeage des deux radicaux libres. Lors des tests d'inhibition de l'absorbance du radical DPPH • , les PI ont varié de (18,15±0,01)% pour la fraction hexanique (2,5 µg/mL) à (92,45±0,01)% pour la fraction d'acétate d'éthyle (100 µg/mL). Avec le radical ABTS +• , les PI ont varié de (52,76±0,05)% pour la fraction hexanique (2,5 µg/mL) à (98,27±0,12)% pour la fraction d'acétate d'éthyle (100 µg/mL). Ainsi, l'extrait éthanolique des feuilles de Vitex doniana et ses différentes fractions possèdent un pouvoir antioxydant significatif.
Journal of Physiology and Pharmacology Advances, 2015
The aim of this study was to determine whether an hydro-alcoolic extract of cloves of Allium sati... more The aim of this study was to determine whether an hydro-alcoolic extract of cloves of Allium sativum is able to induce a relaxant effect in the rat aorta and so the mechanism underlying this effect. Rat aortic rings were suspended in organ chambers for recording of changes in isometric forces. Rings with endothelium were incubated or not with L-Nitro Arginine Methyl Ester (L-NAME) to block NO synthase, before contraction with adrenalin and a concentration relaxation curve to the hydro-alcoolic extract. In some experiments, endothelium was removed before contraction with adrenalin and concentration relaxation to the extract. Prevent effect of the extract was determine with contraction curve to adrenaline in rings with and without endothelium incubated with the extract of Allium sativum. The hydro-alcoolic extract of Allium sativum induces a vasodilatatory effect in the rat aorta contracted with adrenalin. This effect is not endothelium-dependent and is not mediated by NO. Furthermore the extract incubated with aorta rings, is able to prevent the contraction induced by adrenalin. Allium sativum induces vascular relaxation which can explain the benefic effect of this plant in treatment of high blood pressure in Senegal.
In Africa, the use of plants for therapeutic purposes is an ancient practice. In recent years, mu... more In Africa, the use of plants for therapeutic purposes is an ancient practice. In recent years, much scientific work has been spent to the chemistry and toxicology of medicinal plants; there is a particular focus on natural antioxidants in relation to their various therapeutic properties. Therefore, the purpose of our study is to determine the antioxidant activity of aqueous and hydroethanol extracts from the leaves of Azadirachta indica A. Juss a plant known for its many pharmacological properties. The leaves of Azadirachta indica A. Juss were oven dried at 60 degrees for 24 hours and reduced to a fine powder. And, the powder is first extracted with distilled water to obtain the aqueous extract, then with a mixture of distilled water and ethanol 50/50 (v / v) to obtain the hydroethanol extract. Short Research Article Diatta et al.; AJRIB, 2(4): 1-8, 2019; Article no.AJRIB.50878 2 Antioxidant activity was done through the DPPH test, the FRAP method and the fixation of the radical nit...
En Afrique, l'espèce Zanthoxylum zanthoxyloides est largement utilisée dans le traitement de nomb... more En Afrique, l'espèce Zanthoxylum zanthoxyloides est largement utilisée dans le traitement de nombreuses affections comme la drépanocytose, les maladies inflammatoires et les douleurs. Les racines restent les parties de la plante les plus utilisées, ce qui pose le problème de la survie et de l'exploitation durable de l'espèce. Cette présente étude tente de trouver une alternative à l'utilisation des racines en médecine traditionnelle. L'activité anti-inflammatoire a été évaluée sur un modèle d'oedème induit par la carraghénine sur la patte de rat Wistar. L'activité analgésique a été quant à elle, évaluée sur un modèle de douleur à l'acide acétique sur la souris. L'extrait hydroalcoolique de feuilles montre une activité anti-inflammatoire à la dose de 100 mg/kg per os, avec des pourcentages d'inhibition de l'oedème de 36,64% et 50,13% respectivement à la quatrième et sixième heures. A la sixième heure, la dose de 300 mg/kg a une activité supérieure à celle de l'acide acétylsalicylique à la dose de 100 mg/kg, avec des pourcentages d'inhibition respectifs de 85,28% et 55,93%. Cet extrait à la dose de 300 mg/kg est doublé d'un effet analgésique qui est comparable à celui de l'acide acétylsalicylique à la dose de 100 mg/kg per os avec des pourcentages d'inhibition de la douleur respectifs de 72,91% et 73,21%. Ces résultats montrent que les feuilles et les racines sont douées de propriétés anti-inflammatoires et analgésiques. Dans une perspective de sauvegarde de l'espèce, les feuilles pourraient être utilisées à la place des racines dans la prise en charge de ces pathologies.
An ethno-apicultural survey was carried out for the plant species pollinated by honey bees in the... more An ethno-apicultural survey was carried out for the plant species pollinated by honey bees in the green district of Casamance (South Senegal). This survey followed a well-established questionnaire concerning beekeepers in these areas. The listed melliferous flora was made of 61 species either. It’s divided into 58 genera and 30 families though the most represented are in decreasing order Fabaceae with 12 species (19.67%) followed by Rutaceae and Malvaceae with 4 species (6.55% each), Arecaceae, Anacardiaceae, Combretaceae, Gramineae, Myrtaceae, with 3 species (4.91% each), then Chrysobalanaceae, Lamiaceae, Meliaceae and Rubiaceae with 2 species (3.27% each) and then Acanthaceae, Asteraceae, Canabaceae, Verbenaceae, Apocynaceae, Bignoniaceae, Annonaceae, Hymenocardiaceae, Icacinaceae, Lauraceae, Moringaceae, Musaceae, Celastraceae, Rhizophoraceae, Sapindaceae, Sterculiceae, Moraceae, Ochnaceae, with 1 species (1.63% each). Melliferous plants include 47.54% nectariferous plants follow...
Use of plants as remedies dates back to the time of the oldest civilizations. Among these active ... more Use of plants as remedies dates back to the time of the oldest civilizations. Among these active ingredients, polyphenols play an important role. Piliostigma reticulatum, a plant whose barks are rich in condensed tannin is often used as an anti-inflammatory. The purpose of this work was to correlate the anti-inflammatory activity of extracts with their chemical composition through chromatography fractionation analyses (HPLC-DAD and HPLC-MS). The barks were extracted by moderate hydroethanol decoction followed by silica gel splitting with successively ethyl acetate, methanol and water. Anti-inflammatory activity was evaluated by the method of carrageenan induced hind paw edema in Wistar rats. The chemical study was carried out by HPLC-DAD and HPLC-MS after isolation of the compounds by fractionation on Sephadex LH-20 gel. The bark hydroethanolic extract had shown ability to inhibit significantly the inflammation induced by carraghenan. Among the hydroethanolic bark extract fractions...
Spilanthes oleracea Jacq. is an herbaceous plant whose scientific literature attributes among oth... more Spilanthes oleracea Jacq. is an herbaceous plant whose scientific literature attributes among others, anti-malarial and anti-bilharzia properties. These virtues justify the placing on the market of drugs based on the plant.Our study consisted on the one hand to evaluate the biomass of the plant on a soil of dune amended and on soil of unamended dune and to test its vegetative multiplication by transplanting, cuttings and layering.The results show that the growth of the species is greater on dune soil amended with an average biomass of 106.06 g compared to 71.06 g for un-amended soil plants. The transplanting of the plants and the layering were techniques that made it possible to multiply the plants.Spilanthes oleracea Jacq. can be produced using this agronomic data.
Background: The use of plants for healing dates back to very remote times. Nowadays with the acce... more Background: The use of plants for healing dates back to very remote times. Nowadays with the accession of new diseases plants are increasingly used for the formulation of new drugs able to overcome the many diseases (cancer, atherosclerosis) often caused by the disorder of the system prooxidant/antioxidant. Aim/Objective: On the strength of this observation, the research of an antioxidant plant is essential, hence the aim of this study, which is to determine the antioxidant activity of the stalk and the fruit of Solanum aethiopicum L. Methods: The fruits and stalk were washed, cut into fine slats, then dried in the incubator for three days and finally crushed into powder. An extraction by decoction with ethanol (stalks and fruits) and water (fruit) was subsequently carried out to obtain three extracts (ethanol and water). Antioxidant activity was evaluated through the FRAP method, and the trapping of radical DPPH. Results: For the FRAP method, at the highest concentration (1 mg/ml) ...
Asian Journal of Research in Medical and Pharmaceutical Sciences
Background : Nowadays with the appearance of diseases such as cancer, atherosclerosis, free radic... more Background : Nowadays with the appearance of diseases such as cancer, atherosclerosis, free radicals are often singled out. What motivates scientific research in natural antioxidants. Aim/Objective : The aim of this study was to determine the antioxidant activity of the stalks and the fruit of Solanum melongena L. Study Duration : The period of the study was done on 25th July, 2015 at the Department of Pharmacy, Faculty of Medecine, Pharmacy and Odontology, University of Dakar, Senegal. Methodology : Antioxidant activity was evaluated through two methods (DPPH and FRAP). Results : For the FRAP test, at the highest concentration (83.3 µg/ml) the aqueous extract of the fruit (0.90±0.08) has a higher reducing power compared to those of ethanol extracts from the fruit (0.77±0.41) and the stalk (0.85±0.004). These results remain inferior to that of tannic acid (0.95± 0.0005). The DPPH test reveals that the ethanolic extract of the fruit is more effective in reducing the free radical DPPH...
Background: In Africa, particularly in Senegal, 70% of the population resort to traditional medic... more Background: In Africa, particularly in Senegal, 70% of the population resort to traditional medicine. Aim/Objective: The aim of this study is to inventory the plants used to the the treatment of erectile dysfunction, hypertension, diabetes etc because the populations often resort to phytotherapy. Methods: Fifty traditional practitioners, fifty herbalists and fifty resources persons were conducted to identify the plants used in the management of affections in the Tivaouane department. Results: Ninety seven plants could be identified and divided into eighty nine genera and forty eight families. Thus, Fabaceae families with 18 species, Euphorbiaceae (8 species), Combretaceae (5 species), Malvaceae (4 species), Anacardiaceae, Annonaceae, Asteraceae, Meliaceae Myrtaceae and Poaceae each with 3 species and Asclepiadaceae, Liliaceae, Lythraceae, Loganaceae and Menispermaceae each with 2 species; Apocynaceae, Balanitaceae, Bignoniaceae, Capparidaceae, Caricaceae, Casuarinaceae, Celastracea...
Asian Journal of Research in Medical and Pharmaceutical Sciences
HIV / AIDS infection is characterized by the reduction of the body's defenses favoring the oc... more HIV / AIDS infection is characterized by the reduction of the body's defenses favoring the occurrence "opportunistic" infections, as bronchitis, mycoses and tuberculosis etc. Thus, to fight against this virus, antiretrovirals are used. The Ziguinchor district (Senegal) has a higher seroprevalence rate of 2.2% above the national average of 0.7%. It is in this sense that a survey of two herbalists, 35 tradipraticians and eight resource persons was conducted to identify the plants used in the management of opportunistic AIDS diseases because as the populations often resort to phytotherapy. 88 plants were identified and divided into 79 genera and 38 families. Some species were mentioned very more frequently and in many diseases. These are: Cordila pinnata Poir. (78%), Guiera senegalensis (73.1%), Khaya senegalensis (67%), Icacina oliviformis (55%), Terminalia macroptera (55%), Cassia sieberiana (47%), etc. Leaves and roots constituted the greatest use in the form of macera...
This study has surveyed honey plants used by Apis mellifera in the Great Green Wall of Senegal b... more This study has surveyed honey plants used by Apis mellifera in the Great Green Wall of Senegal by involving 38 people (21 in Widou, 17 in Koyli Alpha). The study revealed seventeen species divided into fourteen genera and nine families. Fabaceae was the most represented family with 5 species followed by Combretaceae (3 species), Malvaceae and Rutaceae each with 2 species, and Anacardiaceae, Balanitaceae, Rhamnaceae, Sterculiaceae, Meliaceae each with one species. The most frequent melliferous plant species were : Combretum glutinosum, Guiera senegalensis, Balanites aegyptiaca, Acacia radiana, Lannea acida, Terminalia avicennoides, Sclerocarya birrea, Sterculia setigera and Maytenus senegalensis. The trees were more large with 58.82% followed by shrubs (35.29%) and herbs (5.88%). Spontaneous plants represent 76.47% and cultivated plants represent 23.53%. The melliferous flora was largely dominated by African and Afro-Indian species, which together accounted for 70.58% of the spec...
Uploads
Papers by kady diatta