In a 2-year period, 30 patients with culture-proven mycoses (chromoblastomycosis, sporotrichosis,... more In a 2-year period, 30 patients with culture-proven mycoses (chromoblastomycosis, sporotrichosis, and paracoccidioidomycosis) were treated with the new orally administered triazole, saperconazole (spz) (R66905), The daily dose varied from 100 to 200 mg. All patients responded to treatment; the mean time required to heal the lesions and convert the cultures to negative was 3,5 months for sporotrichosis, 4,6 for paracoccidioidomycosis, and 9,0 for chromoblastomycosis. Evaluation by a scoring system indicated that 36,6% of the patients achieved complete resolution of the pretherapy abnormalities, while the remaining (63,3%) experienced major improvement. No colateral effects were reported; there were no bone-marrow or liver toxicities, SPZ is an effective drug for the treatment of the above-mentioned mycoses and appears to be suitable for the control of chromoblastomycosis, Int J Dermatol 1992; 31:725-729
The sublittoral red alga Delesseria sanguinea was pre-cultivated in the laboratory in a predomina... more The sublittoral red alga Delesseria sanguinea was pre-cultivated in the laboratory in a predominantly green light field at 10 µmol m s (10 °C), with an approximately 0.5% daily increase in blade area. Such pre-cultivated blades were exposed horizontally in flow-through chambers for 5–6 days in April and May to solar radiation reduced to 19% and 11%, respectively, by neutral density screens. In all
Endothelins -specially ET1- are the most potent vaso- constrictors known so far. This effect migh... more Endothelins -specially ET1- are the most potent vaso- constrictors known so far. This effect might be media- ted by an increase in intracellular calcium concentra- tion through ET-A receptor. Although most of the at- tention has been focused this receptor, we will try to explain the relevance that ET-B receptor would have in regulating renal medullar blood flow and natriure-
For the first time, the photosynthetic performance of field-grown macroalgae from the Magellan St... more For the first time, the photosynthetic performance of field-grown macroalgae from the Magellan Strait was evaluated with respect to their photoadaptation in the field and acclimation potential to ultraviolet radiation. Five macroalgal species were collected in the eulittoral and the upper sublittoral: Ulva intestinalis, Porphyra columbina, Adenocystis utricularis, Desmarestia confervoides and D. ligulata. Photosynthesis vs. irradiance (P-I) curves of macroalgae cultivated in the laboratory under low white light intensities more than a week were used to assess the acclimation potential to irradiance conditions in the field. Both, photosynthetic parameters referred to as maximum electron transport rate (ETRmax) and light saturation points of photosynthesis (I k ) were species-specific and did not correlate with the position on the shore. I k ranging between 80 and 215 μmol photons m -2 s -1 was indicative of moderate sun-adaptation in all studied species. The acclimation potential to UV-radiation was determined as the extent and the rates (m inh ) of PSII inhibition (resulting from decreased maximum PSII-quantum yield (Fv/Fm)) after four hours of UV-exposure and as the subsequent rates of recovery (m rec ) in dim PAR. The results suggest that photosynthesis of each species during UV-exposure was transiently down regulated rather than damaged. Furthermore, no reductions in ETRmax were detected after 4 h exposure to UV-A and UV-B-radiation, and consequently the Calvin cycle could not be affected. Thus, Fv/Fm was a more sensitive parameter than ETRmax explaining the photosynthetic UV acclimation. Both, the rates of inhibition and the rates of recovery were not correlated with the morpho-functional groups of macroalgae nor to their vertical distribution. Thus, although the capacity to acclimate to UV-radiation varied among the different species, data suggest that such responses are based on metabolic adjustments or possibly photoprotective strategies. In conclusion and taking into account the light adaptation characteristics, all species collected in the midlittoral and the upper sublittoral at the Strait of Magellan seem to be well acclimated to UV-B doses occurring at their habitat, which might be a pre-requisite to withstand enhanced solar UV-B during ozone depletion or summertime irradiance conditions. La actividad fotosintética de algas provenientes del Estrecho de Magallanes fue medida por primera vez con el propósito de determinar su fotoadaptación en terreno y su potencial de aclimatación a la radiación ultravioleta. Cinco especies fueron recolectadas desde la zona eulitoral y sublitoral superior: Ulva intestinalis, Porphyra columbina, Adenocystis utricularis, Desmarestia confervoides y D. ligulata. Curvas de fotosíntesis versus irradiancia (P-I) medidas en algas cultivadas en el laboratorio por más de una semana fueron usadas para determinar la aclimatación potencial de las algas en su hábitat. Tanto las capacidades fotosintéticas, determinadas a través de la tasa máxima de transporte de electrones (ETRmax), como los puntos de saturación de fotosíntesis (I k ) fueron especies-específicas, no observándose correlaciones con la distribución vertical de Palabras clave: radiación UV, macroalgas, fotosíntesis, fotoaclimatación, Estrecho de Magallanes.
As a result of their morphological complexity, large macroalgae show intra-thallus variations in ... more As a result of their morphological complexity, large macroalgae show intra-thallus variations in their nutritional composition and secondary metabolite content, which influences the trophic ecology of herbivorous invertebrates, and ultimately their fitness. In this study, we evaluated for the first time the variability in nutritional quality (protein content, carbohydrates, lipids, and total organic matter), secondary metabolites (phlorotannins), and structure (shape
So far, very few studies exist on the naı̈ve T cell population of elderly persons. Only recently ... more So far, very few studies exist on the naı̈ve T cell population of elderly persons. Only recently an increase in the percentage of long lived CD4+CD31− naı̈ve T cells has been claimed to occur with aging. We, therefore, characterised CD31+ and CD31− CD45RA+ CD4+ T cells in young and healthy elderly persons. The production of IL-2 and IFN-γ by the
The relationship between O(2)-based gross photosynthesis (GP) and in vivo chlorophyll fluorescenc... more The relationship between O(2)-based gross photosynthesis (GP) and in vivo chlorophyll fluorescence of Photosystem II-based electron transport rate (ETR) as well as the relationship between effective quantum yield of fluorescence (Phi(PSII)) and quantum yield of oxygen evolution (Phi(O_2)) were examined in the green algae Ulva rotundata and Ulva olivascens and the red alga Porphyra leucosticta collected from the field and incubated for 3 days at 100 mumol m(-2) s(-1) in nutrient enriched seawater. Maximal GP was twice as high in Ulva species than that measured in P. leucosticta. In all species ETR was saturated at much higher irradiance than GP. The initial slope of ETR versus absorbed irradiance was higher than that of GP versus absorbed irradiance. Only under absorbed irradiances below saturation or at values of GP <2 mumol O(2) m(-2) s(-1) a linear relationship was observed. In the linear phase, calculated O(2) evolved /ETR molar ratios were closed to the theoretical value of 0...
ObjectivesThe objective of this study was to evaluate whether previous verification of the immune... more ObjectivesThe objective of this study was to evaluate whether previous verification of the immune status against varicella by serology is efficient compared with routine vaccination in all adolescents whose clinical history shows they have not suffered varicella infection.
Understanding the variation of biodiversity along environmental gradients and multiple spatial sc... more Understanding the variation of biodiversity along environmental gradients and multiple spatial scales is relevant for theoretical and management purposes. Hereby, we analysed the spatial variability in diversity and structure of intertidal and subtidal macrobenthic Antarctic communities along vertical environmental stress gradients and across multiple horizontal spatial scales. Since biotic interactions and local topographic features are likely major factors for coastal assemblages, we tested the hypothesis that fine-scale processes influence the effects of the vertical environmental stress gradients on the macrobenthic diversity and structure. We used nested sampling designs in the intertidal and subtidal habitats, including horizontal spatial scales ranging from few centimetres to 1000s of metres along the rocky shore of Fildes Peninsula, King George Island. In both intertidal and subtidal habitats, univariate and multivariate analyses showed a marked vertical zonation in taxon ri...
In this paper, we describe methods for the analysis and design of Cooperative Object-oriented Inf... more In this paper, we describe methods for the analysis and design of Cooperative Object-oriented Information Systems. These methods involve users in the development of general Information Systems much more than traditional ones like Metrica or UML. We introduce a set of cooperative tools, based on a powerful and user friendly graphic interface that facilitates user participation in new stages of
In this paper we present Propos, a novel dynamic Web tool for managing probabilistic and possibil... more In this paper we present Propos, a novel dynamic Web tool for managing probabilistic and possibilistic temporal constraint networks. These networks are a special sort of temporal constraint satisfaction problems, useful for representing and reasoning with uncertain temporal relations between temporal points. They can be applied as an effective formalism in a very different kind of domains. Propos has been developed using dynamic Web technology for mainly, make easier the complex process of interpreting, evaluating, and finally, extracting useful knowledge from the network. It can be viewed as a novel knowledge acquisition tool and, for practical purposes, it will be used for work with temporal patterns extracted from temporal data mining processes.
Biomédica : revista del Instituto Nacional de Salud
The nCD64 receptor, the soluble triggering receptor expressed in myeloid cells (s-TREM-1), and th... more The nCD64 receptor, the soluble triggering receptor expressed in myeloid cells (s-TREM-1), and the high mobility group-box 1 protein (HMGB-1) have been proposed as significant mediators in sepsis. To evaluate the prognostic value of these markers in patients with suspected infection recently admitted in an emergency department (ED). All patients who presented to the ED with suspected infection were eligible for enrollment in this study. Baseline clinical data, Sequential Organ Failure Assessment score (SOFA) score, APACHE II score, HMGB-1 levels, s-TREM-1 levels, and nCD64 levels were analyzed. The HMGB-1 and sTREM-1 serum concentrations were determined using commercially available ELISA kits, and CD64 on the surface of neutrophils was measured by flow cytometry. . A total of 579 patients with suspected infection as their admission diagnosis were enrolled in this study. The median patient age was 50 years (IQR = 35-68). Morbidity during the 28-day followup period was 11.1% (n=64). T...
Large quantities of floating macroalgae are traveling in coastal waters of the SE Pacific and in ... more Large quantities of floating macroalgae are traveling in coastal waters of the SE Pacific and in other temperate climate zones. While afloat, these algae are potentially exposed to full solar radiation, including UVA and UVB, which can have profound effects on their physiological and growth performance. Latitudinal variations in UV-radiation (UVR) are hypothesized to affect floating algae differently with higher
Structural damage detection is a very important research topic and, currently, there are not spec... more Structural damage detection is a very important research topic and, currently, there are not specific tools to solve it. A promising tool that can be used is the artificial neural network, ANN, which can deal with hard problems. This paper uses a back propagation ANN with Bayesian regularization training to locate and quantify damage in truss structures. The input parameters
Previous laboratory studies in species of the Laminariales have revealed that both the onset of g... more Previous laboratory studies in species of the Laminariales have revealed that both the onset of growth in early winter and the summer drop in growth rate are controlled by the annual course of daylength synchronizing endogenous, circannual clocks within the thallus. Moreover, it is known for some laminarian species that cultivation in the laboratory in constant short days (SD) leads
Thallus growth, photosynthetic oxygen evolution and rates of carbon fixation were determined alon... more Thallus growth, photosynthetic oxygen evolution and rates of carbon fixation were determined along the lamina of the endemic Antarctic brown alga Ascoseira mirabilis (Ascoseirales), grown under simulated Antarctic conditions. The meristem is basally located and forms new blade tissue under spring-conditions. Light saturated net photosynthesis (P max ), measured as O 2 production, was higher in the intermediate region of the plant (9.8 μηιοί Ο 2 g" 1 fw h"" 1 )· In general, photosynthetic parameters such as dark respiration, gross photosynthesis, photosynthetic efficiency (a) and photosynthetic light compensation (I c ) increased significantly towards the distal region. Carbon-fixation in A. mirabilis also showed thallus-dependent variation. Rates of light and light independent (dark) carbon fixation increased towards the distal regions ranging between 7.6-9.5 and 1.2-2.0 μηιοί C g" 1 fw h"" 1 respectively. The percentage of light independent carbon fixation (in relation to light 14 C-fixation) also increased from the basal to the distal parts reaching 24% in the distal region of the thallus. The contents of Chi a and Chic, were close to 0.37 and 0.14 mg g" 1 fw respectively and were notably uniform along the lamina. The results indicate that the formation of the blade by a basal meristem and the increase of light carbon fixation rates from base to the distal regions in A. mirabilis are similar compared with certain Laminariales, especially members of the genus Laminaria. However, light independent carbon fixation is highest in the meristems of Laminaria, opposite to the results obtained here for A. mirabilis.
With rare exceptions, the presence of cornoid lamellae in skin biopsy specimens is considered dia... more With rare exceptions, the presence of cornoid lamellae in skin biopsy specimens is considered diagnostic of porokeratosis. Since the initial descriptions of this condition by Mibelli (1893) ^"^ Respighi (1893), there has been debate concerning its relationship to the eccrine sweat duct.
ObjectiveTo determine the prevalence of depression and anxiety in main carers of dependent patien... more ObjectiveTo determine the prevalence of depression and anxiety in main carers of dependent patients as defined by the Dependent Care Law 39/2006.
In a 2-year period, 30 patients with culture-proven mycoses (chromoblastomycosis, sporotrichosis,... more In a 2-year period, 30 patients with culture-proven mycoses (chromoblastomycosis, sporotrichosis, and paracoccidioidomycosis) were treated with the new orally administered triazole, saperconazole (spz) (R66905), The daily dose varied from 100 to 200 mg. All patients responded to treatment; the mean time required to heal the lesions and convert the cultures to negative was 3,5 months for sporotrichosis, 4,6 for paracoccidioidomycosis, and 9,0 for chromoblastomycosis. Evaluation by a scoring system indicated that 36,6% of the patients achieved complete resolution of the pretherapy abnormalities, while the remaining (63,3%) experienced major improvement. No colateral effects were reported; there were no bone-marrow or liver toxicities, SPZ is an effective drug for the treatment of the above-mentioned mycoses and appears to be suitable for the control of chromoblastomycosis, Int J Dermatol 1992; 31:725-729
The sublittoral red alga Delesseria sanguinea was pre-cultivated in the laboratory in a predomina... more The sublittoral red alga Delesseria sanguinea was pre-cultivated in the laboratory in a predominantly green light field at 10 µmol m s (10 °C), with an approximately 0.5% daily increase in blade area. Such pre-cultivated blades were exposed horizontally in flow-through chambers for 5–6 days in April and May to solar radiation reduced to 19% and 11%, respectively, by neutral density screens. In all
Endothelins -specially ET1- are the most potent vaso- constrictors known so far. This effect migh... more Endothelins -specially ET1- are the most potent vaso- constrictors known so far. This effect might be media- ted by an increase in intracellular calcium concentra- tion through ET-A receptor. Although most of the at- tention has been focused this receptor, we will try to explain the relevance that ET-B receptor would have in regulating renal medullar blood flow and natriure-
For the first time, the photosynthetic performance of field-grown macroalgae from the Magellan St... more For the first time, the photosynthetic performance of field-grown macroalgae from the Magellan Strait was evaluated with respect to their photoadaptation in the field and acclimation potential to ultraviolet radiation. Five macroalgal species were collected in the eulittoral and the upper sublittoral: Ulva intestinalis, Porphyra columbina, Adenocystis utricularis, Desmarestia confervoides and D. ligulata. Photosynthesis vs. irradiance (P-I) curves of macroalgae cultivated in the laboratory under low white light intensities more than a week were used to assess the acclimation potential to irradiance conditions in the field. Both, photosynthetic parameters referred to as maximum electron transport rate (ETRmax) and light saturation points of photosynthesis (I k ) were species-specific and did not correlate with the position on the shore. I k ranging between 80 and 215 μmol photons m -2 s -1 was indicative of moderate sun-adaptation in all studied species. The acclimation potential to UV-radiation was determined as the extent and the rates (m inh ) of PSII inhibition (resulting from decreased maximum PSII-quantum yield (Fv/Fm)) after four hours of UV-exposure and as the subsequent rates of recovery (m rec ) in dim PAR. The results suggest that photosynthesis of each species during UV-exposure was transiently down regulated rather than damaged. Furthermore, no reductions in ETRmax were detected after 4 h exposure to UV-A and UV-B-radiation, and consequently the Calvin cycle could not be affected. Thus, Fv/Fm was a more sensitive parameter than ETRmax explaining the photosynthetic UV acclimation. Both, the rates of inhibition and the rates of recovery were not correlated with the morpho-functional groups of macroalgae nor to their vertical distribution. Thus, although the capacity to acclimate to UV-radiation varied among the different species, data suggest that such responses are based on metabolic adjustments or possibly photoprotective strategies. In conclusion and taking into account the light adaptation characteristics, all species collected in the midlittoral and the upper sublittoral at the Strait of Magellan seem to be well acclimated to UV-B doses occurring at their habitat, which might be a pre-requisite to withstand enhanced solar UV-B during ozone depletion or summertime irradiance conditions. La actividad fotosintética de algas provenientes del Estrecho de Magallanes fue medida por primera vez con el propósito de determinar su fotoadaptación en terreno y su potencial de aclimatación a la radiación ultravioleta. Cinco especies fueron recolectadas desde la zona eulitoral y sublitoral superior: Ulva intestinalis, Porphyra columbina, Adenocystis utricularis, Desmarestia confervoides y D. ligulata. Curvas de fotosíntesis versus irradiancia (P-I) medidas en algas cultivadas en el laboratorio por más de una semana fueron usadas para determinar la aclimatación potencial de las algas en su hábitat. Tanto las capacidades fotosintéticas, determinadas a través de la tasa máxima de transporte de electrones (ETRmax), como los puntos de saturación de fotosíntesis (I k ) fueron especies-específicas, no observándose correlaciones con la distribución vertical de Palabras clave: radiación UV, macroalgas, fotosíntesis, fotoaclimatación, Estrecho de Magallanes.
As a result of their morphological complexity, large macroalgae show intra-thallus variations in ... more As a result of their morphological complexity, large macroalgae show intra-thallus variations in their nutritional composition and secondary metabolite content, which influences the trophic ecology of herbivorous invertebrates, and ultimately their fitness. In this study, we evaluated for the first time the variability in nutritional quality (protein content, carbohydrates, lipids, and total organic matter), secondary metabolites (phlorotannins), and structure (shape
So far, very few studies exist on the naı̈ve T cell population of elderly persons. Only recently ... more So far, very few studies exist on the naı̈ve T cell population of elderly persons. Only recently an increase in the percentage of long lived CD4+CD31− naı̈ve T cells has been claimed to occur with aging. We, therefore, characterised CD31+ and CD31− CD45RA+ CD4+ T cells in young and healthy elderly persons. The production of IL-2 and IFN-γ by the
The relationship between O(2)-based gross photosynthesis (GP) and in vivo chlorophyll fluorescenc... more The relationship between O(2)-based gross photosynthesis (GP) and in vivo chlorophyll fluorescence of Photosystem II-based electron transport rate (ETR) as well as the relationship between effective quantum yield of fluorescence (Phi(PSII)) and quantum yield of oxygen evolution (Phi(O_2)) were examined in the green algae Ulva rotundata and Ulva olivascens and the red alga Porphyra leucosticta collected from the field and incubated for 3 days at 100 mumol m(-2) s(-1) in nutrient enriched seawater. Maximal GP was twice as high in Ulva species than that measured in P. leucosticta. In all species ETR was saturated at much higher irradiance than GP. The initial slope of ETR versus absorbed irradiance was higher than that of GP versus absorbed irradiance. Only under absorbed irradiances below saturation or at values of GP <2 mumol O(2) m(-2) s(-1) a linear relationship was observed. In the linear phase, calculated O(2) evolved /ETR molar ratios were closed to the theoretical value of 0...
ObjectivesThe objective of this study was to evaluate whether previous verification of the immune... more ObjectivesThe objective of this study was to evaluate whether previous verification of the immune status against varicella by serology is efficient compared with routine vaccination in all adolescents whose clinical history shows they have not suffered varicella infection.
Understanding the variation of biodiversity along environmental gradients and multiple spatial sc... more Understanding the variation of biodiversity along environmental gradients and multiple spatial scales is relevant for theoretical and management purposes. Hereby, we analysed the spatial variability in diversity and structure of intertidal and subtidal macrobenthic Antarctic communities along vertical environmental stress gradients and across multiple horizontal spatial scales. Since biotic interactions and local topographic features are likely major factors for coastal assemblages, we tested the hypothesis that fine-scale processes influence the effects of the vertical environmental stress gradients on the macrobenthic diversity and structure. We used nested sampling designs in the intertidal and subtidal habitats, including horizontal spatial scales ranging from few centimetres to 1000s of metres along the rocky shore of Fildes Peninsula, King George Island. In both intertidal and subtidal habitats, univariate and multivariate analyses showed a marked vertical zonation in taxon ri...
In this paper, we describe methods for the analysis and design of Cooperative Object-oriented Inf... more In this paper, we describe methods for the analysis and design of Cooperative Object-oriented Information Systems. These methods involve users in the development of general Information Systems much more than traditional ones like Metrica or UML. We introduce a set of cooperative tools, based on a powerful and user friendly graphic interface that facilitates user participation in new stages of
In this paper we present Propos, a novel dynamic Web tool for managing probabilistic and possibil... more In this paper we present Propos, a novel dynamic Web tool for managing probabilistic and possibilistic temporal constraint networks. These networks are a special sort of temporal constraint satisfaction problems, useful for representing and reasoning with uncertain temporal relations between temporal points. They can be applied as an effective formalism in a very different kind of domains. Propos has been developed using dynamic Web technology for mainly, make easier the complex process of interpreting, evaluating, and finally, extracting useful knowledge from the network. It can be viewed as a novel knowledge acquisition tool and, for practical purposes, it will be used for work with temporal patterns extracted from temporal data mining processes.
Biomédica : revista del Instituto Nacional de Salud
The nCD64 receptor, the soluble triggering receptor expressed in myeloid cells (s-TREM-1), and th... more The nCD64 receptor, the soluble triggering receptor expressed in myeloid cells (s-TREM-1), and the high mobility group-box 1 protein (HMGB-1) have been proposed as significant mediators in sepsis. To evaluate the prognostic value of these markers in patients with suspected infection recently admitted in an emergency department (ED). All patients who presented to the ED with suspected infection were eligible for enrollment in this study. Baseline clinical data, Sequential Organ Failure Assessment score (SOFA) score, APACHE II score, HMGB-1 levels, s-TREM-1 levels, and nCD64 levels were analyzed. The HMGB-1 and sTREM-1 serum concentrations were determined using commercially available ELISA kits, and CD64 on the surface of neutrophils was measured by flow cytometry. . A total of 579 patients with suspected infection as their admission diagnosis were enrolled in this study. The median patient age was 50 years (IQR = 35-68). Morbidity during the 28-day followup period was 11.1% (n=64). T...
Large quantities of floating macroalgae are traveling in coastal waters of the SE Pacific and in ... more Large quantities of floating macroalgae are traveling in coastal waters of the SE Pacific and in other temperate climate zones. While afloat, these algae are potentially exposed to full solar radiation, including UVA and UVB, which can have profound effects on their physiological and growth performance. Latitudinal variations in UV-radiation (UVR) are hypothesized to affect floating algae differently with higher
Structural damage detection is a very important research topic and, currently, there are not spec... more Structural damage detection is a very important research topic and, currently, there are not specific tools to solve it. A promising tool that can be used is the artificial neural network, ANN, which can deal with hard problems. This paper uses a back propagation ANN with Bayesian regularization training to locate and quantify damage in truss structures. The input parameters
Previous laboratory studies in species of the Laminariales have revealed that both the onset of g... more Previous laboratory studies in species of the Laminariales have revealed that both the onset of growth in early winter and the summer drop in growth rate are controlled by the annual course of daylength synchronizing endogenous, circannual clocks within the thallus. Moreover, it is known for some laminarian species that cultivation in the laboratory in constant short days (SD) leads
Thallus growth, photosynthetic oxygen evolution and rates of carbon fixation were determined alon... more Thallus growth, photosynthetic oxygen evolution and rates of carbon fixation were determined along the lamina of the endemic Antarctic brown alga Ascoseira mirabilis (Ascoseirales), grown under simulated Antarctic conditions. The meristem is basally located and forms new blade tissue under spring-conditions. Light saturated net photosynthesis (P max ), measured as O 2 production, was higher in the intermediate region of the plant (9.8 μηιοί Ο 2 g" 1 fw h"" 1 )· In general, photosynthetic parameters such as dark respiration, gross photosynthesis, photosynthetic efficiency (a) and photosynthetic light compensation (I c ) increased significantly towards the distal region. Carbon-fixation in A. mirabilis also showed thallus-dependent variation. Rates of light and light independent (dark) carbon fixation increased towards the distal regions ranging between 7.6-9.5 and 1.2-2.0 μηιοί C g" 1 fw h"" 1 respectively. The percentage of light independent carbon fixation (in relation to light 14 C-fixation) also increased from the basal to the distal parts reaching 24% in the distal region of the thallus. The contents of Chi a and Chic, were close to 0.37 and 0.14 mg g" 1 fw respectively and were notably uniform along the lamina. The results indicate that the formation of the blade by a basal meristem and the increase of light carbon fixation rates from base to the distal regions in A. mirabilis are similar compared with certain Laminariales, especially members of the genus Laminaria. However, light independent carbon fixation is highest in the meristems of Laminaria, opposite to the results obtained here for A. mirabilis.
With rare exceptions, the presence of cornoid lamellae in skin biopsy specimens is considered dia... more With rare exceptions, the presence of cornoid lamellae in skin biopsy specimens is considered diagnostic of porokeratosis. Since the initial descriptions of this condition by Mibelli (1893) ^"^ Respighi (1893), there has been debate concerning its relationship to the eccrine sweat duct.
ObjectiveTo determine the prevalence of depression and anxiety in main carers of dependent patien... more ObjectiveTo determine the prevalence of depression and anxiety in main carers of dependent patients as defined by the Dependent Care Law 39/2006.
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Papers by Ivan Gomez