Papers by Tadesse Belayneh
International Journal of Health Sciences, 2019
Objective: Cervical cancer, which is caused by human papillomavirus, is one of the common cancers... more Objective: Cervical cancer, which is caused by human papillomavirus, is one of the common cancers in women worldwide. The proportion of precancerous cervical lesion among HIV-infected women has not been investigated yet in this study area. The aim of this study was to determine the proportion of precancerous cervical lesion and associated factors among HIV-infected women on ART in Woldia and Dessie Hospitals, Amhara Regional State, Ethiopia. Methods: A hospital-based cross-sectional study was conducted on 284 HIV patients. Data were collected using a structured questionnaire and visual inspection. Pap smear test was employed for confirmation of cancer. Descriptive statistics were used to summarize findings. A logistic regression model was considered to identify predictors of precancerous cervical lesions. Those variables with P < 0.05 at a 95% confidence interval were considered as statistically significant. Results: The overall proportion of precancerous lesion among HIV-infecte...
Ecology Letters, 2010
Matrix projection models are among the most widely used tools in plant ecology. However, the way ... more Matrix projection models are among the most widely used tools in plant ecology. However, the way in which plant ecologists use and interpret these models differs from the way in which they are presented in the broader academic literature. In contrast to calls from earlier reviews, most studies of plant populations are based on < 5 matrices and present simple metrics such as deterministic population growth rates. However, plant ecologists also cautioned against literal interpretation of model predictions. Although academic studies have emphasized testing quantitative model predictions, such forecasts are not the way in which plant ecologists find matrix models to be most useful. Improving forecasting ability would necessitate increased model complexity and longer studies. Therefore, in addition to longer term studies with better links to environmental drivers, priorities for research include critically evaluating relative ⁄ comparative uses of matrix models and asking how we can use many short-term studies to understand long-term population dynamics.
Journal of Blood Transfusion, Nov 28, 2013
Background. Although blood ordering is a common practice in surgical field, the average requireme... more Background. Although blood ordering is a common practice in surgical field, the average requirement for a particular procedure is usually based on subjective anticipation of blood loss rather than on evidence based estimates. Overordering with minimal utilization squanders technical time, reagent and imposes extra expenses on patients. This study was conducted to assess blood utilization practices. Methods. Cross-sectional study was conducted in Gondar Hospital. Five-month data were collected from all discharged surgical patients and blood bank registries. Blood utilization was calculated using crossmatch to transfusion ratio (C/T), transfusion probability (%T), and transfusion index (TI) indices. Results. A total of 982 patients were requested to prepare 1,072 crossmatched units. Of these, 468 units were transfused for 286 patients. The overall ratios of C/T, %T, and TI index were 2.3, 47%, and 0.77, respectively. Blood transfusion from the units crossmatched was 43.6%. Moreover, the highest C/T ratio was observed in elective surgical patients. Conclusions. The overall blood utilization was encouraging, but excessive crossmatching with minimal transfusion practice was observed in elective surgical patients. Blood ordering pattern for elective procedures needs to be revised and overordering of blood should be minimized. Moreover, the hospital with blood transfusion committee should formulate maximum surgical blood ordering policies for elective surgical procedures and conduct regular auditing.
Research Square (Research Square), Dec 22, 2020
Background Symptomatic prolapse impairs quality of life. Health-related quality of life (HRQoL) i... more Background Symptomatic prolapse impairs quality of life. Health-related quality of life (HRQoL) is considered an important outcome of pelvic organ prolapse (POP) surgery. However, it is rarely reported, and measures are inadequately used. Thus, studies reporting patient-reported surgical outcomes in lowincome contexts are needed. This study aims to evaluate the effect of prolapse surgery on patient HRQoL and determine the predictive factors for change in HRQoL. Methods A total of 215 patients who had prolapse stage III or IV were enrolled. Patients underwent vaginal native tissue repair, and their HRQoL was evaluated at baseline, 3 and 6 months postoperatively. Effect of surgery on subjective outcomes were measured using validated Prolapse Quality of Life (P-QoL-20), Prolapse Symptom Score (POP-SS), Body Image in Prolapse (BIPOP), Patient Health Questionnaire (PHQ-9), and Patient Global Index of Improvement (PGI-I) tools. A linear mixed-effect model was used to compare pre-and postoperative P-QoL scores and investigate potential predictors of the changes in P-QoL scores. Results In total, 193 (89.7%) patients were eligible for analysis at 3 months, and 185 (86.0%) at 6 months. Participant's mean age was 49.3±9.4 years. The majority of patients had prolapse stage III (81.9%) and underwent vaginal hysterectomy (55.3%). All domains of P-QoL improved signi cantly after surgery. Altogether more than 72% of patients reported clinically meaningful improvement in condition-speci c quality of life measured with P-QoL-20 at 6 months. An improvement in POP-SS, BIPOP, and the PHQ-9 scores were also observed during both follow-up assessments. At 6 months after surgery, only 2.7% of
Annals of medicine and surgery, Sep 1, 2021
Background Knowledge of health care professionals on postoperative nausea and vomiting (PONV) and... more Background Knowledge of health care professionals on postoperative nausea and vomiting (PONV) and antiemetic prescription trends affects patient's outcome after surgery and anesthesia and also patient and family satisfaction. Hence, knowing the knowledge status of health professionals towards PONV management is vital for the optimal care of surgical patients. Therefore, the study aimed to assess the knowledge and factors associated with PONV management among health professionals in referral hospitals of Northwest Ethiopia. Methods An institutional based cross-sectional study was conducted on 407 health care professionals from March 1 to 30, 2019. A Simple random sampling technique was used to select the study participants. Both bivariable and multivariable logistic regression analysis were used to identify factors associated with the knowledge level of health professionals on PONV management. In the multivariable analysis, variables with a p-value <0.05 were considered statistically significant. Results In this study, about 52.8% (95% CI: 47.9, 57.2) of the participants had good knowledge of PONV management. Being male (AOR = 1.95; 95% CI: 1.20, 3.17), Physician (AOR = 5.36; 95% CI: 2.20, 13.5), Anesthetist (AOR = 3.88; 95% CI: 1.66, 9.08), and taking training on PONV management (AOR = 5.32; 95%CI: 1.58, 17.89) were positively associated with good knowledgeable of health professionals about PONV management. Conclusion and recommendation: More than half of health care professionals who are working in the perioperative sites of the referral hospitals had good knowledge about the PONV management. Being male, Physician, Anesthetist and taking in-service training on PONV management were significantly affecting the knowledge level of health professionals on PONV management. Thus, providing regular in-service training on PONV management, especially for physician and anesthetist is highly recommended.
International Urogynecology Journal, Nov 21, 2018
Introduction and hypothesis We aimed to translate and culturally adapt the Pelvic Organ Prolapse ... more Introduction and hypothesis We aimed to translate and culturally adapt the Pelvic Organ Prolapse Symptom Score (POP-SS) into Amharic and evaluate its psychometric properties. Methods We followed an intercultural adaptation procedure to translate and adapt the POP-SS. One hundred and eighty-six women with POP symptoms completed the Amharic POP-SS and Prolapse Quality of Life (P-QoL) questionnaires. All women were examined using a simplified Pelvic Organ Prolapse Quantification (SPOP-Q) system and were divided into four groups based on the POP-Q scores as stage 1, 2, 3, and 4. Internal consistency and test-retest reliability were determined using Cronbach's alpha and the intraclass correlation coefficient (ICC), respectively. Criterion validity was assessed against the SPOP-Q stage and the P-QoL scale. Furthermore, we tested construct validity using exploratory factor analysis. Results The POP-SS score was successfully translated and achieved good content validity. It had high internal consistency (Cronbach's alpha = 0.86) and test-retest reliability (ICC = 0.81; p < 0.001). There was a statistically significant difference among four groups of stages in POP-SS score. and women with stage 3 had the highest median score (Kruskal-Wallis test; p < 0.05). The POP-SS score was also significantly correlated with the P-QoL score (Spearman's correlation coefficient = 0.28, p < 0.001). The exploratory factor analysis identified two factors, namely, physical symptoms and evacuation symptoms. Conclusions The POP-SS scale was successfully translated to Amharic and appears reliable and valid for women with symptoms of POP. However, further studies are needed to evaluate its responsiveness.
Tuberculosis Research and Treatment, 2016
Background. During tuberculosis treatment, patients may transfer to continue treatment at another... more Background. During tuberculosis treatment, patients may transfer to continue treatment at another health facility. To ensure adherence until treatment completion, keeping track of patients is paramount. This study aimed to investigate treatment outcomes of patients who transferred out from the University of Gondar Hospital. Methods. This was a retrospective cohort evaluation of patients registered from 2009 to 2013. Treatment outcomes were collected from the TB registers of receiving units using a standardized data capture format. Results. During the study period 3,707 patients initiated treatment and 47.5% (1,760) transferred out. The study evaluated the outcome of 26% (457/1,760) patients, of whom 403 (88%) arrived in the receiving units. Overall, 79% were successfully treated and 13.8% transferred out for a second time. For all transferred-out cases, treatment outcomes were not reported to the referring unit. Conclusion and Recommendation. About half of the patients were transferred out to complete treatment elsewhere. Although successful treatment outcome was obtained in 79% of patients, these results were not fed back to the referring unit. Implementing a clear mechanism to communicate the arrival of and treatment outcome for transfer-out patients and appropriate patient education on treatment unit selection before treatment and during transfer-out are recommended.
Journal of Pregnancy, 2014
Background. Early booking of antenatal care (ANC) is regarded as a cornerstone of maternal and ne... more Background. Early booking of antenatal care (ANC) is regarded as a cornerstone of maternal and neonatal health care. However, existing evidence from developing countries indicate that lots of pregnant woman begin ANC booking lately. Objective. It was aimed to assess timing of ANC booking and associated factors among pregnant women attending ANC clinic at University of Gondar Hospital, 2013. Methods. An institution based cross-sectional study design was used to collect data with a face-to-face interview technique. Bivariate and multivariate analysis was used to identify associated factors for early ANC visit using SPSS version 20. Results. From total women (N = 369) interviewed, 47.4% were timely booked. Mothers with younger age (AOR = 3.83, 95% CI: 1.89, 10.53), formal education (AOR = 1.06, 95% CI: 1.03, −7.61), previous early ANC visit (AOR = 2.39, 95% CI: 2.23, 9.86), and perceived ANC visit per pregnancy of four and greater were significantly associated with early ANC visit. Conclusions. Although late booking is a problem in this study, previous early utilization of ANC visit favors current timely booking. This indicates that the importance of early booking was appropriately addressed from previous visits. Counseling of timely booking during ANC visit should be strengthened. Moreover, empowering through education is also recommended.
International Journal of Surgery Open, 2020
Atomistic and coarse-grained simulations can be a great help in uncovering the mechanisms of phys... more Atomistic and coarse-grained simulations can be a great help in uncovering the mechanisms of physical processes at microscopic and mesoscopic levels at time scales ranging from femtoseconds to milliseconds. Any simulation study involves (1) setting up an appropriate simulation system representing the physical problem, (2) running the simulation and collecting information about the system, and (3) analyzing the collected data. The last step eventually leads to final conclusions about the system. Software for molecular simulation has been in development for many years and a number of high quality freely distributed general purpose simulation packages is available for researchers. Data analysis tools are usually less general as they often depend on a specific research project and the system under investigation. While many simulation packages come with a set of some general data analysis utilities, it is not unusual for such analysis tools to be developed on a per project basis inside research groups. Interestingly, there is a very limited set of available tools for setting up simulation systems, even though this is the very first and vital step of every simulation study. This lack of convenient general simulation system generators sometimes may even dictate the kind of simulations done based on the available initial systems rather than on the system being the best for a particular problem. In this work we describe a general software tool, bio.b-gen, for the creation of initial systems for biological molecular simulations. A number of case systems are demonstrated using an atomistic force field as well as the coarse grained MARTINI force field. The tool is designed to generate initial systems for the GROMACS general simulation package.
Journal of Anesthesia and Clinical Research, 2014
Background: Hypothermia (i.e., temperature <36°C) is a common incident in the immediate postopera... more Background: Hypothermia (i.e., temperature <36°C) is a common incident in the immediate postoperative period. However, it is usually diagnosed and treated infrequently. Maintaining normal body temperature will reduce hospital stay, surgical site infection, postoperative blood transfusions, pressure ulcers, subjective discomfort and mortality. The aim of this study was to identify magnitude and factors associated with postoperative hypothermia. Methods: Hospital based cross sectional study was conducted at University of Gondar Hospital. All consecutive postoperative (N= 384) patients that underwent scheduled or emergency surgery were included. Tympanic membrane temperature was measured before surgery and on arrival at recovery room via clinical nurses. Analysis was done using version 20 SPSS and binary logistic regression was utilized to identify associated factors. Result: The incidence of postoperative hypothermia at Recovery Room was 30.72%. Of these, 30 (27.96%) and 43 (34.44%) were mild and moderate respectively, with no severe hypothermia. Surgical patient operated under general anesthesia was more likely to develop postoperative hypothermia than spinal anesthesia (AOR, 1.84; 95% CI, 1.17; 3.24). Additionally, those with higher ASA physical status were at higher risk of postoperative hypothermia (AOR, 1.99; 95% CI, 1.16; 3.44). Temperature was not routinely taken by health care providers in the preoperative and intraoperative period. Conclusion and recommendation: Incidence of postoperative hypothermia at Recovery Room was high. Patient with high ASA physical status and operated under general anesthesia were significant factors for the development of postoperative hypothermia. Anesthesia providers along with perioperative surgical team should participate to reduce the occurrence of postoperative hypothermia with early prediction and diagnosis, especially in high risk groups.
International Urogynecology Journal, Apr 26, 2019
Introduction and hypothesisDue to linguistic and cultural differences, there is a need to test th... more Introduction and hypothesisDue to linguistic and cultural differences, there is a need to test the psychometrics of the translated versions of any patient-reported outcome measures. We investigated the psychometric properties of the Prolapse Quality of Life (P-QoL) questionnaire for non-English-speaking populations by conducting a systematic review of studies that examined the psychometric properties of non-English versions.MethodsWe searched PubMed, Latin American and Caribbean Health Science Information Center (LILACS), and Science Direct databases for articles published in English up to February 2018. Methodological quality and quality of psychometric properties were assessed by two independent reviewers using the Consensus-based Standards for the Selection of Health Measurement Instruments (COSMIN) checklist and validated quality assessment criteria. The two assessments were combined to produce the best level of evidence per language/translation.ResultsSixteen articles in 13 languages were retrieved. Most (n = 9; 56.3%) were not rigorously translated or reported, and there was poor evidence for structural validity. Internal consistency was reported in all studies, and all studies had good methodological quality. There was fair evidence for construct and good to fair for criterion validity. Evidence for responsiveness was good, although this was evaluated only in three studies.ConclusionsThere is limited evidence supporting the psychometric robustness of the original validation and translated versions of P-QoL. Cross-cultural adaptations are insufficient. Given this variability, the individual psychometrics of a translation must be considered prior to use. Responsiveness, measurement error, and cutoff values should also be assessed to increase the clinical utility and psychometric robustness of the translated versions.
Health and Quality of Life Outcomes, Jan 14, 2019
Background: The Prolapse Quality of Life (P-QoL) is a disease-specific instrument designed to mea... more Background: The Prolapse Quality of Life (P-QoL) is a disease-specific instrument designed to measure the healthrelated quality of life in women with prolapse; however, there is no Amharic version of the instrument. The aim of this study were to translate the P-QoL into Amharic and evaluate its psychometric properties among adult women. Methods: We followed an intercultural adaptation procedure to translate and adapt the P-QoL. A forwardbackward translation, face validity interviews with experts and cognitive debriefing of the translated version with ten adults from the target group were performed. The Amharic version was then completed by 230 adult women with and without POP symptoms. All women were examined using a simplified Pelvic Organ Prolapse Quantification (SPOP-Q) system. We examined internal consistency (Cronbach's alpha) and test-retest reliability (intraclass correlation coefficient = ICC). Confirmatory factor analysis (CFA) was conducted and model fit was discussed. We extracted a new factor structure by exploratory factor analysis (EFA). Criterion validity was also assessed against the SPOP-Q stage. Results: The translated measure was found acceptable by the experts and target group, with only minor adaptations required for the Amharic context. It had high internal consistency (α = 0.96) and test-retest reliability (ICC = 0.87; p < 0.001). In CFA results, the model fit indices were unacceptable (CFI = 0.69, RMSEA = 0.17, SRMR = 0.43, TLI = 0.65, and PCLOSE = 0.00). EFA extracted three-factor with satisfactory convergent and discriminant validity. The P-QoL median scores were significantly higher in symptomatic women (Mann-Whitney U Test; p < 0.001). The score was also significantly correlated with stage of prolapse (Spearman's correlation coefficient = 0.42 to 0.64, p < 0.001). Conclusions: The P-QoL scale was successfully translated to Amharic and appears feasible, reliable and valid for Amharicspeaking women. Factor analysis confirmed a three-factor structure, inconsistent with the original English version. Further studies are needed to evaluate responsiveness of the Amharic P-QoL score.
PLOS ONE, Nov 26, 2018
Background The majority of women suffering from maternal morbidities live in resource-constrained... more Background The majority of women suffering from maternal morbidities live in resource-constrained settings with diverse barriers preventing access to quality biomedical health care services. This study aims to highlight the dynamics between the public health system and alternative healing through an exploration of the experiences of health care seeking among women living with severe symptomatic pelvic organ prolapse in an impoverished setting.
Background Good knowledge conjoined with evident practice of postoperative nausea, and vomiting m... more Background Good knowledge conjoined with evident practice of postoperative nausea, and vomiting management is vital for the optimal management of patients. On the other hand, inadequate knowledge and poor practice of health professionals on postoperative nausea vomiting risk reduction and management come up with complications, reduce patient satisfaction, increase patient, and hospital costs. Objective To assess knowledge, practice, and predictors of knowledge regarding postoperative nausea and vomiting management among health professionals working in referral hospitals in northwest Ethiopia. Methods A multicenter cross-sectional study was conducted on 407 health professionals from February 27 to March 30, 2019, in referral hospitals in northwest Ethiopia. Strati ed random Sampling followed by simple random sampling was used to select the study participants. Both bivariable and multivariable logistic regression were used to identify factors associated with the knowledge level of health professionals in PONV management. In the multivariable analysis, variables with a p-value <0.05 were considered statistically signi cant. Results 52.8% of the study participants had good knowledge of PONV management (95% CI: 47.9-57.2). Male professionals were 1.95 times more likely knowledgeable as compared with females. The odds of physicians being knowledgeable were 5.36 times more likely than midwives, while the odds of anesthetists being knowledgeable were 3.88 times more likely than midwives. Professionals trained on PONV management were 5.32 (AOR: 5.32; 95%CI: 1.58, 17.89) times more likely knowledgeable than those who did not train. Conclusions Nearly fty % of healthcare providers working in the perioperative working areas had poor knowledge of PONV management. Gender, profession, and training on PONV management were factors signi cantly affecting the knowledge level of health professionals. Regular training seminars, continuous professional development, adherence to the latest guidelines, and conducting clinical audits are recommended to increase knowledge and improve the practices of health professionals in postoperative nausea vomiting management.
PurposePelvic Floor Disorders (PFDs) affects many women and have a significant impact on their qu... more PurposePelvic Floor Disorders (PFDs) affects many women and have a significant impact on their quality of life. Pelvic Floor Impact Questionnaire (PFIQ-7) and Pelvic Floor Distress Inventory (PFDI-20) help to assess PFDs; however, both are not culturally translated into the Amharic-language. Hence, we aimed to translate the English versions of short forms of the PFDI-20 and PFIQ-7 into Amharic-language and evaluate their psychometric properties in Amharic-speaking Ethiopian women with symptomatic PFDs.MethodsThe PFDI-20 and PFIQ-7 were translated into Amharic language using standard procedures. The Amharic versions were completed by 197 patients (response rate 92%) with PFDs from University of Gondar specialized and comprehensive Hospital. Internal consistency and test-retest reliability were examined through Cronbach’s alpha and Intraclass correlation coefficients (ICC). A relative criterion standard, POP-SS-7 score, was correlated with total PFDI-20 and subscale POPDI-6 scores (sp...
Additional file 1. Health Related Quality of Life scores among follow-up and lost to follow-up pa... more Additional file 1. Health Related Quality of Life scores among follow-up and lost to follow-up participants.
Copyright © 2014 Tadesse Belayneh et al. This is an open access article distributed under the Cre... more Copyright © 2014 Tadesse Belayneh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Background. Early booking of antenatal care (ANC) is regarded as a cornerstone of maternal and neonatal health care. However, existing evidence fromdeveloping countries indicate that lots of pregnant woman beginANCbooking lately.Objective. It was aimed to assess timing of ANC booking and associated factors among pregnant women attending ANC clinic at University of Gondar Hospital, 2013. Methods. An institution based cross-sectional study design was used to collect data with a face-to-face interview technique. Bivariate and multivariate analysis was used to identify associated factors for early ANC visit using SPSS version 20. Results. From total women (N = 369) interviewed, 47.4 % were timely booked. Mothers with younger age (AOR =...
Copyright © 2013 Tadesse Belayneh et al. This is an open access article distributed under the Cre... more Copyright © 2013 Tadesse Belayneh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Background. Although blood ordering is a common practice in surgical field, the average requirement for a particular procedure is usually based on subjective anticipation of blood loss rather than on evidence based estimates. Overordering with minimal utilization squanders technical time, reagent and imposes extra expenses on patients. This study was conducted to assess blood utilization practices. Methods. Cross-sectional study was conducted in Gondar Hospital. Five-month data were collected from all discharged surgical patients and blood bank registries. Blood utilization was calculated using crossmatch to transfusion ratio (C/T), transfusion probability (%T), and transfusion index (TI) indices. Results. A total of 982 patients w...
Amharic version of P-QoL questionnaire. (DOCX 481 kb)
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Papers by Tadesse Belayneh