Abstract
AIMS:
To assess the effectiveness of intra-articular injections of sodium hyaluronate (N... more Abstract AIMS: To assess the effectiveness of intra-articular injections of sodium hyaluronate (NaH) or corticosteroids (CS) for treatment of intracapsular temporomandibular disorders (TMD).
METHODS: Single- or double-blinded randomized controlled trials (RCTs) on the effectiveness of NaH or CS injections, compared to each other or to placebo, for the treatment of intracapsular TMD due to osteoarthritis and/or internal joint derangement were analyzed in this systematic review and meta-analysis. Electronic searches of MEDLINE through the PubMed, Web of Science, and Cochrane Library databases were conducted on March 17, 2015, and an updated search was conducted on June 7, 2017. Three reviewers independently extracted the data and assessed the risk of bias of included studies.
RESULTS: An initial search yielded 245 studies, and 5 additional studies were identified through cross referencing. A total of 22 studies were identified as relevant based on the abstracts, but only 7 RCTs met the inclusion criteria. Six of the included studies had unclear risk of bias, and one had high risk of bias. Four studies were eligible for meta-analysis. Pooled results showed no significant difference in short- or long-term pain improvement with NaH compared to CS. The number of responders to NaH was significantly more than placebo in one study, but not significantly higher than CS in another study.
CONCLUSION: Although there was no significant difference between the effectiveness of NaH and CS intra-articular injections, there was some evidence that NaH was better than placebo. Further research is needed to determine the minimum effective dose and long-term side effects of both injections.
This thesis is lovingly dedicated to my mother Norma Alvaro Moldez, most wonderful and compassion... more This thesis is lovingly dedicated to my mother Norma Alvaro Moldez, most wonderful and compassionate mother anyone could ever have.
Objective: To quantify relevant cephalometric parameters for Filipinos according to age and sex. ... more Objective: To quantify relevant cephalometric parameters for Filipinos according to age and sex. Materials and Methods: A total of 157 Filipino subjects (78 males, 79 females) who fulfilled specific criteria were selected from elementary, high school, and college students affiliated with Manila Central University. They were divided into comparison groups (GI, GII, GIII, and GIV) on the basis of chronological age and sex. Lateral cephalograms were taken for all subjects, and the mean and standard deviation for each parameter was recorded and compared among groups. Results: The male group had a longer anterior cranial base (S-N), total facial height (N-Me), longer lower anterior facial height (N-ANS), longer ramus height (Cd-Go), longer lower posterior dentoalveolar height (Mo-MiЈ), and total mandibular length (Gn-Cd) than the female group. All these linear measurements were statistically significantly different between males and females in GI, GIII, and GIV. On the other hand, SNB angle showed significant differences (P ϭ .0271) in GIV only. In the lower third of the face, significant opposite tendencies were found in GIV. The female group showed a clockwise rotation, whereas the male counterpart had a counterclockwise rotation of the mandibular plane. The denture pattern of both groups was characterized by a proclination of both lower incisor (Ii to MP) and upper incisor (Is to SN). Conclusions: Convexity due to dentoalveolar protrusion is the naturally occurring facial profile for Filipinos. The adult females showed steeper mandibular and occlusal plane angles than the male samples.
Abstract
AIMS:
To assess the effectiveness of intra-articular injections of sodium hyaluronate (N... more Abstract AIMS: To assess the effectiveness of intra-articular injections of sodium hyaluronate (NaH) or corticosteroids (CS) for treatment of intracapsular temporomandibular disorders (TMD).
METHODS: Single- or double-blinded randomized controlled trials (RCTs) on the effectiveness of NaH or CS injections, compared to each other or to placebo, for the treatment of intracapsular TMD due to osteoarthritis and/or internal joint derangement were analyzed in this systematic review and meta-analysis. Electronic searches of MEDLINE through the PubMed, Web of Science, and Cochrane Library databases were conducted on March 17, 2015, and an updated search was conducted on June 7, 2017. Three reviewers independently extracted the data and assessed the risk of bias of included studies.
RESULTS: An initial search yielded 245 studies, and 5 additional studies were identified through cross referencing. A total of 22 studies were identified as relevant based on the abstracts, but only 7 RCTs met the inclusion criteria. Six of the included studies had unclear risk of bias, and one had high risk of bias. Four studies were eligible for meta-analysis. Pooled results showed no significant difference in short- or long-term pain improvement with NaH compared to CS. The number of responders to NaH was significantly more than placebo in one study, but not significantly higher than CS in another study.
CONCLUSION: Although there was no significant difference between the effectiveness of NaH and CS intra-articular injections, there was some evidence that NaH was better than placebo. Further research is needed to determine the minimum effective dose and long-term side effects of both injections.
This thesis is lovingly dedicated to my mother Norma Alvaro Moldez, most wonderful and compassion... more This thesis is lovingly dedicated to my mother Norma Alvaro Moldez, most wonderful and compassionate mother anyone could ever have.
Objective: To quantify relevant cephalometric parameters for Filipinos according to age and sex. ... more Objective: To quantify relevant cephalometric parameters for Filipinos according to age and sex. Materials and Methods: A total of 157 Filipino subjects (78 males, 79 females) who fulfilled specific criteria were selected from elementary, high school, and college students affiliated with Manila Central University. They were divided into comparison groups (GI, GII, GIII, and GIV) on the basis of chronological age and sex. Lateral cephalograms were taken for all subjects, and the mean and standard deviation for each parameter was recorded and compared among groups. Results: The male group had a longer anterior cranial base (S-N), total facial height (N-Me), longer lower anterior facial height (N-ANS), longer ramus height (Cd-Go), longer lower posterior dentoalveolar height (Mo-MiЈ), and total mandibular length (Gn-Cd) than the female group. All these linear measurements were statistically significantly different between males and females in GI, GIII, and GIV. On the other hand, SNB angle showed significant differences (P ϭ .0271) in GIV only. In the lower third of the face, significant opposite tendencies were found in GIV. The female group showed a clockwise rotation, whereas the male counterpart had a counterclockwise rotation of the mandibular plane. The denture pattern of both groups was characterized by a proclination of both lower incisor (Ii to MP) and upper incisor (Is to SN). Conclusions: Convexity due to dentoalveolar protrusion is the naturally occurring facial profile for Filipinos. The adult females showed steeper mandibular and occlusal plane angles than the male samples.
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Papers by Marlon Moldez
AIMS:
To assess the effectiveness of intra-articular injections of sodium hyaluronate (NaH) or corticosteroids (CS) for treatment of intracapsular temporomandibular disorders (TMD).
METHODS:
Single- or double-blinded randomized controlled trials (RCTs) on the effectiveness of NaH or CS injections, compared to each other or to placebo, for the treatment of intracapsular TMD due to osteoarthritis and/or internal joint derangement were analyzed in this systematic review and meta-analysis. Electronic searches of MEDLINE through the PubMed, Web of Science, and Cochrane Library databases were conducted on March 17, 2015, and an updated search was conducted on June 7, 2017. Three reviewers independently extracted the data and assessed the risk of bias of included studies.
RESULTS:
An initial search yielded 245 studies, and 5 additional studies were identified through cross referencing. A total of 22 studies were identified as relevant based on the abstracts, but only 7 RCTs met the inclusion criteria. Six of the included studies had unclear risk of bias, and one had high risk of bias. Four studies were eligible for meta-analysis. Pooled results showed no significant difference in short- or long-term pain improvement with NaH compared to CS. The number of responders to NaH was significantly more than placebo in one study, but not significantly higher than CS in another study.
CONCLUSION:
Although there was no significant difference between the effectiveness of NaH and CS intra-articular injections, there was some evidence that NaH was better than placebo. Further research is needed to determine the minimum effective dose and long-term side effects of both injections.
AIMS:
To assess the effectiveness of intra-articular injections of sodium hyaluronate (NaH) or corticosteroids (CS) for treatment of intracapsular temporomandibular disorders (TMD).
METHODS:
Single- or double-blinded randomized controlled trials (RCTs) on the effectiveness of NaH or CS injections, compared to each other or to placebo, for the treatment of intracapsular TMD due to osteoarthritis and/or internal joint derangement were analyzed in this systematic review and meta-analysis. Electronic searches of MEDLINE through the PubMed, Web of Science, and Cochrane Library databases were conducted on March 17, 2015, and an updated search was conducted on June 7, 2017. Three reviewers independently extracted the data and assessed the risk of bias of included studies.
RESULTS:
An initial search yielded 245 studies, and 5 additional studies were identified through cross referencing. A total of 22 studies were identified as relevant based on the abstracts, but only 7 RCTs met the inclusion criteria. Six of the included studies had unclear risk of bias, and one had high risk of bias. Four studies were eligible for meta-analysis. Pooled results showed no significant difference in short- or long-term pain improvement with NaH compared to CS. The number of responders to NaH was significantly more than placebo in one study, but not significantly higher than CS in another study.
CONCLUSION:
Although there was no significant difference between the effectiveness of NaH and CS intra-articular injections, there was some evidence that NaH was better than placebo. Further research is needed to determine the minimum effective dose and long-term side effects of both injections.