Jorge Folch-mallol

Universidad Autónoma del Estado de Morelos, Centro De Investigación En Biotecnología, Faculty Member

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Dr. Jorge L. Folch-Mallol obtained his degree in Basic Biomedical Research studying the genetics of nitrogen assimilation in the yeast Saccharomyces cerevisiae at the National Autonomous University of Mexico (UNAM). Then he went to Spain for his Ph.D. studies where he worked in the genetics and molecular biology of the symbiotic relation between Rhizobium tropici and several host plants in a collaboration with Dr. Herman Spaink at the University of Leiden (The Netherlands).
Back in Mexico, he worked as an associate researcher in the Institute of Biotechnology of the UNAM using S. cerevisiae as a model to study heat stress.

He has been dedicated for the last 15 years to study ligninolyitc fungi and their lignocellulose decomposing machinery (cellulases, laccases, esterases and peroxidases, for example), since this substrate is a proved source for biofuel production. We have described novel fungal accessory proteins such as amorphogenetic proteins that disrupt the crystalline structure of cellulose (loosenins and expansins) and esterases. We have also studied thermostable xylanases and cellulases from ascomycetes and basidiomycetes.

The oxidative enzymes from these fungi also have capabilities to degrade xenobiotic compounds. Through molecular biology techniques he has described novel genes and enzymes involved in the transformation of industrial dyes, endocrine disruptors, pesticides and aromatic polycyclic hydrocarbons. Currently he and his group are working on the search for robust enzymes that can degrade xenobiotic substances or be used for biorefinery purposes.
We have recently begun to study plant growth-promoting organisms based on their properties to affect cell wall structure

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Assessment of non-cultured aquatic fungal diversity from different habitats in Mexico Estimación de la diversidad de hongos acuáticos no-cultivables de diferentes hábitats en México

With the aim to explore the diversity of aquatic fungi in Mexico we present an investigation usin... more With the aim to explore the diversity of aquatic fungi in Mexico we present an investigation using a fragment of the 18S ribosomal DNA as a molecular marker obtained from different water bodies (marine, brackish and fresh water). Ribosomal gene fragments were obtained by DNA amplification, the resulting sequences were compared using multiple alignments against a collection of classified reference fungal sequences and then subjected to phylogenetic clustering allowing the identification and classification of DNA sequences from environmental isolates as fungal down to the family level, provided enough reference sequence were available. From our ensemble of 2,020 sequences identified as fungal, 23.8% were classified at the family level, 48.5% at the order level, 13% at the class/subphylum level and 14.7% of the sequences (all from the same site) could not be unambiguously positioned in any of our reference fungal groups but were closely related to uncultivated marine fungi. The most frequently recovered phylum was Ascomycota (89.1%), followed by Chytridiomycota (8.1%), Basidiomycota (2.8%) and Mucoromycotina (1.3%).

Jorge Folch-mallol

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