Lifelong learner. Clinical Breast Cancer. Research Scientist at @aiims_newdelhi 🧑🔬Standing on the shoulders of giants🧑🔬
Jan 1, 2022 • 781 tweets • >60 min read
For the year 2022, I aim to read one research (/review) article per day, every day. This thread will summarise the essence of the paper. While oncology is my field of interest, I will also explore papers from other domains and classics, of course. Bon voyage.📋 #APaperADay
Day 1 of #APaperADay challenge. I read this classic piece of Dr Barbara McClintock where she described the transposons. It was a seminal discovery breaking the age-old concept of the linear arrangement of genes like beads on a string. pnas.org/content/36/6/3…
Dec 19, 2020 • 41 tweets • 23 min read
Briefing on Gene knockdown and knockout in today's #365DaysOfScience. These two are classical genome editing tools used to study gene function and probable effects of inhibiting the target gene. These tools find relevance in molecular genetics and drug discovery.
Gene knockout is the 'knocking out' of a gene. It is attributed by the permanent deactivation or complete elimination of gene function to evaluate the functional specificity of that gene. It is achieved by homologous recombination, endonucleases, or CRISPR/Cas9. #365DaysOfScience
Jan 1, 2020 • 833 tweets • >60 min read
The new year begins and I usher into a scientific journey where I shall be challenging myself with scientific quest and reviewing a scientific article/blog/interview/technique or facts on a daily basis. (or at least try😉) #365DaysOfScience
Let the journey begin.
The most cited article (over 300,000 times) is the @jbiolchem paper for a technique to estimate protein concentration in a solution. The paper is "Protein measurement with the folin phenol reagent". #365DaysOfScience
Image: @nature
